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Acetyl-CoA acetyltransferase, mitochondrial Hydroxymethylglutaryl- CoA synthase, mitochondrial Hydroxymethylglutaryl- CoA lyase, mitochondrial Succinyl-CoA:3- ketoacid coenzyme A transferase 1, mitochondrial D-beta- hydroxybutyrate dehydrogenase, mitochondrial Acetoacetyl-CoA 3-Hydroxy-3- methylglutaryl- CoA Acetyl-CoA Acetone Acetone Acetone CoA H2O CoA Acetoacetic acid Succinyl-CoA Succinic acid (R)-3- Hydroxybutyric acid NAD NADH CO2 Fatty Acid Metabolism Pyruvate Metabolism Steroid Biosynthesis Pyruvate Metabolism Cytoplasm Extracellular Space Mitochondria Mitochondrial matrix
Mitochondria ACAT1 HMGCS2 HMGCL OXCT1 BDH1 Acetoacetyl-CoA 3-Hydroxy-3- methylglutaryl- CoA Acetyl-CoA Acetone Acetone Acetone Coenzyme A Water Coenzyme A Acetoacetic acid Succinyl-CoA Succinic acid (R)-3- Hydroxybutyric acid NAD NADH Carbon dioxide Fatty Acid Metabolism Pyruvate Metabolism Steroid Biosynthesis Pyruvate Metabolism
ACAT1 HMGCS2 HMGCL OXCT1 BDH1 ActaCoA HMG-CoA Ac-CoA Acetone Acetone Acetone CoA H2O CoA LIN Suc-CoA Succini BHIB NAD NADH CO2 PW000023 PW000054 PW000050 PW000054 Cytoplasm Extracellular Space Mitochondria Mitochondrial matrix
Mitochondria ACAT1 HMGCS2 HMGCL OXCT1 BDH1 ActaCoA HMG-CoA Ac-CoA Acetone Acetone Acetone CoA H2O CoA LIN Suc-CoA Succini BHIB NAD NADH CO2 PW000023 PW000054 PW000050 PW000054