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RAC-alpha serine/threonine- protein kinase Forkhead box protein O1 Mitogen- activated protein kinase 8 Insulin receptor Insulin RAC-alpha serine/threonine- protein kinase Solute carrier family 2, facilitated glucose transporter member 4 Activated Phosphatidylinositol 4,5- bisphosphate 3-kinase complex Phosphoinositide 3-kinase regulatory subunit 6 Insulin receptor substrate 2 Insulin receptor substrate 1 Phosphatidylinositol- 4,5- bisphosphate 3-kinase catalytic subunit gamma isoform GTPase HRas Phosphoinositide 3-kinase regulatory subunit 6 Phosphatidylinositol- 4,5- bisphosphate 3-kinase catalytic subunit gamma isoform Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 1 Insulin receptor substrate 2 SHC- transforming protein 1 SHC- transforming protein 1 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 SHC- transforming protein 1 Growth factor receptor-bound protein 2 Son of sevenless homolog 1 Insulin receptor substrate 1 SHC- transforming protein 1 Growth factor receptor-bound protein 2 Son of sevenless homolog 1 GTPase HRas GTPase HRas 3- phosphoinositide- dependent protein kinase 1 RAF proto-oncogene serine/threonine- protein kinase GTPase HRas RAF proto-oncogene serine/threonine- protein kinase Inactive Dual specificity mitogen- activated protein kinase kinase 1 Active Dual specificity mitogen- activated protein kinase kinase 1 Inactive Dual specificity mitogen- activated protein kinase kinase 2 Active Dual specificity mitogen- activated protein kinase kinase 2 Inactive Mitogen- activated protein kinase 1 Active Mitogen- activated protein kinase 1 Forkhead box protein O1 D-Glucose D-Glucose PIP2(16:0/16:0) PIP3(16:0/16:0) GTP GDP Magnesium Phosphate Guanosine triphosphate Phosphate Phosphate Phosphate Phosphate Phosphate Phosphate Phosphate Guanosine diphosphate Guanosine triphosphate Zinc Guanosine triphosphate Zinc Phosphate Phosphate Magnesium Magnesium Phosphate Phosphate Carbohydrate Protein Fatty Acid Starch and Sucrose Metabolism Insulin secretion Activation Activation Cytoplasm Blood Stream Mitgoensis Stress
AKT1 FOXO1 MAPK8 INSR Unknown AKT1 SLC2A4 PIK3CG Unknown Unknown Unknown PIK3CG HRAS Unknown PIK3CG Unknown Unknown Unknown Unknown Unknown Unknown GRB2 Unknown Unknown GRB2 SOS1 Unknown Unknown GRB2 SOS1 HRAS HRAS PDPK1 RAF1 HRAS RAF1 MAP2K1 MAP2K1 MAP2K2 MAP2K2 MAPK1 MAPK1 FOXO1 D-Glucose D-Glucose PIP2(16:0/16:0) PIP3(16:0/16:0) Guanosine triphosphate Guanosine diphosphate Carbohydrate Protein Fatty Acid Starch and Sucrose Metabolism Insulin secretion
AKT1 FOXO1 MAPK8 INSR AKT1 SLC2A4 PIK3CG PIK3CG HRAS PIK3CG GRB2 GRB2 SOS1 GRB2 SOS1 HRAS HRAS PDPK1 RAF1 HRAS RAF1 MAP2K1 MAP2K1 MAP2K2 MAP2K2 MAPK1 MAPK1 FOXO1 D-Glc D-Glc PIP216 PIP316 GTP GDP Mg2+ Pi GTP Pi Pi Pi Pi Pi Pi Pi GDP GTP Zinc GTP Zinc Pi Pi Mg2+ Mg2+ Pi Pi Carbohy Protein FA PW000150 PW122156 Activation Activation Cytoplasm Blood Stream Mitgoensis Stress
AKT1 FOXO1 MAPK8 INSR AKT1 SLC2A4 PIK3CG PIK3CG HRAS PIK3CG GRB2 GRB2 SOS1 GRB2 SOS1 HRAS HRAS PDPK1 RAF1 HRAS RAF1 MAP2K1 MAP2K1 MAP2K2 MAP2K2 MAPK1 MAPK1 FOXO1 D-Glc D-Glc PIP216 PIP316 GTP GDP Carbohy Protein FA PW000150 PW122156