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Showing 1541 - 1560 of 1588 proteins

Protein ID

Protein

Pathways

Q9HAW7

View in UniProt

HMDBP00494

View in HMDB

UDP-glucuronosyltransferase 1-7

Gene Name: UGT1A7

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.

Q9HAW9

View in UniProt

HMDBP00485

View in HMDB

UDP-glucuronosyltransferase 1-8

Gene Name: UGT1A8

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.

O60656

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HMDBP00484

View in HMDB

UDP-glucuronosyltransferase 1-9

Gene Name: UGT1A9

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.

O75310

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HMDBP00491

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UDP-glucuronosyltransferase 2B11

Gene Name: UGT2B11

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.

P54855

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HMDBP00481

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UDP-glucuronosyltransferase 2B15

Gene Name: UGT2B15

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens.

O75795

View in UniProt

HMDBP00488

View in HMDB

UDP-glucuronosyltransferase 2B17

Gene Name: UGT2B17

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The major substrates of this isozyme are eugenol > 4-methylumbelliferone > dihydrotestosterone (DHT) > androstane-3-alpha,17-beta-diol (3-alpha-diol) > testosterone > androsterone (ADT).

P06133

View in UniProt

HMDBP00458

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UDP-glucuronosyltransferase 2B4

Gene Name: UGT2B4

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.

P16662

View in UniProt

HMDBP00480

View in HMDB

UDP-glucuronosyltransferase 2B7

Gene Name: UGT2B7

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Its unique specificity for 3,4-catechol estrogens and estriol suggests it may play an important role in regulating the level and activity of these potent and active estrogen metabolites. Is also active with androsterone, hyodeoxycholic acid and tetrachlorocatechol (in vitro).

Q16222

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HMDBP01079

View in HMDB

UDP-N-acetylhexosamine pyrophosphorylase

Gene Name: UAP1

Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.

P30085

View in UniProt

HMDBP00003

View in HMDB

UMP-CMP kinase

Gene Name: CMPK1

Catalyzes specific phosphoryl transfer from ATP to UMP and CMP.

Q5EBM0

View in UniProt

HMDBP07409

View in HMDB

UMP-CMP kinase 2, mitochondrial

Gene Name: CMPK2

May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs.

Unknown

View in UniProt

Unknown

Unknown

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Unknown

Q15849

View in UniProt

HMDBP02521

View in HMDB

Urea transporter 2

Gene Name: SLC14A2

Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.

A8K5J1

View in UniProt

Uridine monophosphate synthetase isoform A

Gene Name: UMPS

O95045

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HMDBP06424

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Uridine phosphorylase 2

Gene Name: UPP2

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.

Q9NWZ5

View in UniProt

HMDBP07410

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Uridine-cytidine kinase-like 1

Gene Name: UCKL1

May contribute to UTP accumulation needed for blast transformation and proliferation.

Q96N76

View in UniProt

HMDBP00914

View in HMDB

Urocanate hydratase

Gene Name: UROC1

DB00013

View in DrugBank

Urokinase

P06132

View in UniProt

HMDBP00250

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Uroporphyrinogen decarboxylase

Gene Name: UROD

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
Showing 1541 - 1560 of 1588 proteins