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Proteins

Showing 51 - 100 of 3622 proteins
ID Protein Pathways

P37689

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2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Gene Name: gpmM

P76082

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2,3-dehydroadipyl-CoA hydratase

Gene Name: paaF

Catalyzes the reversible conversion of enzymatically produced 2,3-dehydroadipyl-CoA into 3-hydroxyadipyl-CoA.

P15047

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2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

Gene Name: entA

Involved in oxidoreductase activity. 2,3-dihydro-2,3-dihydroxybenzoate + NAD(+) = 2,3-dihydroxybenzoate + NADH.

P0ABR9

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2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase

Gene Name: mhpB

Involved in iron ion binding. Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively.

P37672

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2,3-diketo-L-gulonate reductase

Gene Name: dlgD

Involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.

P32626

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2,3-dioxomethiopentane-1-phosphate enolase/phosphatase

Gene Name: UTR4

Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).

Q9LTV6

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2,4-dienoyl-CoA reductase

Gene Name: At3g12800

2,4-dienoyl-CoA reductase is an enzyme in the peroxisome that is theorized to catalyze a reaction in fatty acid beta-oxidation II whereby a trans-2,trans-4-dienoyl-CoA is converted into a trans-3-enoyl-CoA.

P42593

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2,4-dienoyl-CoA reductase [NADPH]

Gene Name: fadH

Involved in catalytic activity. Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA.

P33312

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2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase

Gene Name: RIB7

Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

Q46857

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2,5-diketo-D-gluconic acid reductase A

Gene Name: dkgA

Involved in oxidoreductase activity. Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives.

P30863

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2,5-diketo-D-gluconic acid reductase B

Gene Name: dkgB

Involved in oxidoreductase activity. Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).

P77231

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2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase

Gene Name: citG

Involved in ATP binding. Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA.

Q8TDX5

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HMDBP00261

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2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

Gene Name: ACMSD

Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.

P0AB77

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2-amino-3-ketobutyrate coenzyme A ligase

Gene Name: kbl

Involved in glycine C-acetyltransferase activity. Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.

O75600

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HMDBP00049

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2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

Gene Name: GCAT

P26281

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2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

Gene Name: folK

Involved in 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity. ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8- dihydropteridine = AMP + (2-amino-4-hydroxy-7,8-dihydropteridin-6- yl)methyl diphosphate.

Q96SZ5

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HMDBP08667

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2-aminoethanethiol dioxygenase

Gene Name: ADO

P62617

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2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

Gene Name: ispF

Involved in 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity. Converts 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) and CMP. Also converts 4-diphosphocytidyl-2-C-methyl-D- erythritol into 2-C-methyl-D-erythritol 3,4-cyclophosphate and CMP.

Q46893

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2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Gene Name: ispD

Involved in catalytic activity. Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP).

Z0Z000

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2-carboxy-1,4-naphthoquinol reductase

Gene Name: ?

2-carboxy-1,4-naphthoquinol reductase is a predicted enzyme in the chloroplast that is theorized to convert 2-carboxy-1,4-naphthoquinol into 2-carboxy-1,4-naphthoquinone.

Q0WUA3

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2-carboxy-1,4-naphthoquinone phytyltransferase

Gene Name: ABC4

2-carboxy-1,4-naphthoquinone phytyltransferase is an enzyme localized to the chloroplast membrane that catalyzes a reaction in the phylloquinol biosynthesis pathway whereby phytyl diphosphate and 2-carboxy-1,4-naphthoquinone are converted into demethylphylloquinone.

Q6BF16

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2-dehydro-3-deoxy-6-phosphogalactonate aldolase

Gene Name: dgoA

Involved in catalytic activity. 2-dehydro-3-deoxy-D-galactonate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate.

P37769

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2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase

Gene Name: kduD

Involved in 2-deoxy-D-gluconate 3-dehydrogenase activity. Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH.

P31459

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2-dehydro-3-deoxygalactonokinase

Gene Name: dgoK

Carbohydrate transport and metabolism. ATP + 2-dehydro-3-deoxy-D-galactonate = ADP + 2-dehydro-3-deoxy-D-galactonate 6-phosphate.

P37647

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2-dehydro-3-deoxygluconokinase

Gene Name: kdgK

Involved in phosphotransferase activity, alcohol group as acceptor. ATP + 2-dehydro-3-deoxy-D-gluconate = ADP + 6- phospho-2-dehydro-3-deoxy-D-gluconate.

P0A715

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2-dehydro-3-deoxyphosphooctonate aldolase

Gene Name: kdsA

Involved in catalytic activity. Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth.

P0A9J4

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2-dehydropantoate 2-reductase

Gene Name: panE

Involved in oxidation-reduction process. Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

P38787

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2-dehydropantoate 2-reductase

Gene Name: PAN5

Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

P38071

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2-enoyl thioester reductase

Gene Name: ETR1

Required for respiration and the maintenance of the mitochondrial compartment. Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2-decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis.

P0ABQ2

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2-hydroxy-3-oxopropionate reductase

Gene Name: garR

Involved in 3-hydroxyisobutyrate dehydrogenase activity. (R)-glycerate + NAD(P)(+) = 2-hydroxy-3- oxopropanoate + NAD(P)H.

P77161

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2-hydroxy-3-oxopropionate reductase_

Gene Name: glxR

Involved in 3-hydroxyisobutyrate dehydrogenase activity. (R)-glycerate + NAD(P)(+) = 2-hydroxy-3- oxopropanoate + NAD(P)H.

P77044

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2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase

Gene Name: mhpC

Involved in catalytic activity. Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid.

Q9LF46

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2-hydroxyacyl-CoA lyase

Gene Name: HACL

Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.

Q9UJ83

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HMDBP08729

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2-hydroxyacyl-CoA lyase 1

Gene Name: HACL1

Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde.

Q16880

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HMDBP01101

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2-hydroxyacylsphingosine 1-beta-galactosyltransferase

Gene Name: UGT8

Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.

P06208

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2-isopropylmalate synthase

Gene Name: LEU4

Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).

P09151

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2-isopropylmalate synthase

Gene Name: leuA

Involved in 2-isopropylmalate synthase activity. Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).

Q12166

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2-isopropylmalate synthase LEU9

Gene Name: LEU9

Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). Redundant to LEU4, responsible of about 20% of alpha-IPMS activity. Involved in leucine synthesis.

P0A712

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2-keto-3-deoxygluconate permease

Gene Name: kdgT

Involved in 2-keto-3-deoxygluconate:hydrogen symporter activity. The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system.

P77608

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2-keto-4-pentenoate hydratase

Gene Name: mhpD

Involved in catalytic activity. Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid.

Q5HYK3

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HMDBP07419

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2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

Gene Name: COQ5

Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity).

Q9LY74

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2-methyl-6-phytyl-1,4-hydroquinone methyltransferase

Gene Name: VTE3

2-methyl-6-phytyl-1,4-hydroquinone methyltransferase is an enzyme localized to the chloroplast membrane that catalyzes a reaction in the plastoquinol-9 biosynthesis pathway whereby 2-methyl-6-solanesyl-1,4-benzoquinol is converted into plastoquinol-9.

P77243

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2-methylcitrate dehydratase

Gene Name: prpD

Involved in 2-methylcitrate dehydratase activity. Catalyzes the dehydration of 2-methylcitrate to 2- methyl-cis-aconitate. Also seems to be responsible for the residual aconitase activity of the acnAB-null strain.

P31660

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2-methylcitrate synthase

Gene Name: prpC

Involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer. Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate. Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity.

P13669

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2-O-α-mannosyl-D-glycerate PTS permease

Gene Name: mngR

Represses mngA and mngB. Regulates its own expression.

P75728

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2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase

Gene Name: ubiF

Involved in oxidoreductase activity. Oxygenase that introduces the hydroxyl group at carbon five of 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol.

P25534

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2-octaprenyl-6-methoxyphenol hydroxylase

Gene Name: ubiH

Involved in oxidoreductase activity. Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone.

A0A0A1AE59

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2-octaprenyl-6-methoxyphenyl hydroxylase

Gene Name: ECONIH1_16735

P25535

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2-octaprenylphenol hydroxylase

Gene Name: ubiI

FAD-dependent monooxygenase required for the aerobic hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the first hydroxylation step in coenzyme Q (ubiquinone) biosynthesis.

P0AFG3

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2-oxoglutarate dehydrogenase E1 component

Gene Name: sucA

Involved in oxoglutarate dehydrogenase (succinyl-transferring) activity. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components:2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
Showing 51 - 100 of 3622 proteins