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1.0 6022 PubChem-compound 937 ChemSpider UDP-glucose 4-epimerase Galactose-1-phosphate uridylyltransferase 53477780 PubChem-compound 2956-16-3 CAS UTP--glucose-1-phosphate uridylyltransferase 1.0 C00794 KEGG Compound LACTOSE BioCyc 439153 PubChem-compound P09848 UniProt C18H32O16 Raffinose 504.16904 6133 PubChem-compound C00446 KEGG Compound 388480 ChemSpider ATP BioCyc C24H42O21 Stachyose 666.22186 53188-23-1 CAS myo-Inositol 559142 ChemSpider 1.0 P15291 UniProt SMILES COC1OC(CO)C(OC2OC(CO)C(OC)C(O)C2O)C(O)C1O 39300-87-3 CAS 1.0 BTO:0000759 BRENDA TISSUE ONTOLOGY 5743 ChemSpider 1.0 Galactose-1-phosphate uridylyltransferase 5742 ChemSpider Beta-galactosidase 2.0 2280-44-6 CAS ALPHA-GLUCOSE-16-BISPHOSPHATE BioCyc P16278 UniProt Alpha-galactosidase A MYO-INOSITOL BioCyc 11357 ChemSpider 2.0 SMILES OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O 2.0 UTP--glucose-1-phosphate uridylyltransferase 53477679 PubChem-compound 6031 PubChem-compound Epimelibiose 133-89-1 CAS Beta-galactosidase C00103 KEGG Compound 1.0 608-66-2 CAS 439165 PubChem-compound 1.0 PPI BioCyc C9H18O8 Galactosylglycerol 254.10017 C12H24O11 Melibiitol 344.13187 CHEBI:17268 ChEBI C6H13O9P Galactose 1-phosphate 260.02972 SubPathwayInteraction475 SubPathwayReaction SubPathway475Reaction 10239179 ChemSpider C00116 KEGG Compound HMDB0006790 HMDB 388558 ChemSpider 5768 ChemSpider SubPathwayInteraction479 SubPathwayReaction SubPathway479Reaction 59-56-3 CAS 388311 ChemSpider 50-70-4 CAS Adenosine triphosphate 1.0 Phosphoglucomutase-1 P15121 UniProt HMDB0006791 HMDB HMDB0006792 HMDB 8.0 389536 ChemSpider C6H12O6 D-Fructose 180.06339 C00009 KEGG Compound C00008 KEGG Compound 389538 ChemSpider 389537 ChemSpider C12H22O11 Epimelibiose 342.1162 C00243 KEGG Compound C00001 KEGG Compound CHEBI:18361 ChEBI Alpha-D-Glucose SubPathwayInput Lactase-phlorizin hydrolase C00004 KEGG Compound CHEBI:18367 ChEBI C00003 KEGG Compound C01697 KEGG Compound 1032 ChemSpider C00002 KEGG Compound C00492 KEGG Compound GLC-1-P BioCyc C6H12O6 Alpha-D-Glucose 180.06339 84571 PubChem-compound 388775 ChemSpider C21H28N7O14P2 NAD 664.11694 HMDB0000902 HMDB C00137 KEGG Compound Beta-1,4-galactosyltransferase 1 C00015 KEGG Compound Glucose-6-phosphatase C00013 KEGG Compound Extracellular Space C00029 KEGG Compound 59-23-4 CAS 56-65-5 CAS 53-84-9 CAS Galactose 1-phosphate C01235 KEGG Compound C00267 KEGG Compound 1.0 SubPathwayInteraction480 SubPathway480Reaction SubPathwayReaction SubPathwayInteraction481 SubPathwayReaction SubPathway481Reaction HMDB0004162 HMDB 1.0 C02336 KEGG Compound C00031 KEGG Compound C00159 KEGG Compound BiologicalState29 Homo sapiens, Liver SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O HMDB0001586 HMDB Water HMDB0005826 HMDB HMDB0000258 HMDB 123912 PubChem-compound SMILES OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O Intestinal Microflora SubPathway HMDB0000250 HMDB SMILES [O-]P([O-])(=O)OP([O-])([O-])=O HMDB0000131 HMDB HMDB0001341 HMDB 753 PubChem-compound GLYCEROL BioCyc Uridine 5'-diphosphate 15-DIDEOXY-15-IMINO-D-GALACTITOL BioCyc Uridine diphosphategalactose MELIBIOSE BioCyc SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 C00052 KEGG Compound SMILES OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO Aldose reductase C9H14N2O12P2 Uridine 5'-diphosphate 404.0022 D-Fructose HMDB0000143 HMDB UTP BioCyc 1.0 5903 ChemSpider 1.0 CHEBI:28061 ChEBI CHEBI:17164 ChEBI 18068 PubChem-compound Hexokinase-1 7732-18-5 CAS CHEBI:16077 ChEBI CHEBI:4170 ChEBI SMILES OC[C@H]1O[C@H](OC[C@H]2OC(O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1O HMDB0001487 HMDB 110443 ChemSpider Alpha-galactosidase A 1.0 1.0 492-62-6 CAS Lysosomal alpha-glucosidase C10H16N5O13P3 Adenosine triphosphate 506.99576 388624 ChemSpider 892 PubChem-compound 1.0 HMDB0000169 HMDB HMDB0000048 HMDB SMILES OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO SMILES OC[C@H]1O[C@H](OC2[C@H](O)[C@@H](O)C(O)[C@@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O CHEBI:28053 ChEBI HMDB0003553 HMDB HMDB0000286 HMDB HMDB0000285 HMDB 962 PubChem-compound 5800 ChemSpider 58-98-0 CAS C00075 KEGG Compound Phosphate CPD-170 BioCyc C05402 KEGG Compound 733 ChemSpider C05401 KEGG Compound Galactosylglycerol C6H12O6 D-Mannose 180.06339 HMDB0002111 HMDB HMDB0000295 HMDB SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O Sorbitol 5809 ChemSpider P07902 UniProt C12H22O11 Alpha-Lactose 342.1162 14265-44-2 CAS 1.0 C00089 KEGG Compound 58-64-0 CAS NADH C6H13O9P Glucose 1-phosphate 260.02972 C00092 KEGG Compound HMDB0003213 HMDB 71358 ChemSpider CHEBI:4167 ChEBI 2255-14-3 CAS 1.0 HMDB0000186 HMDB C15H24N2O17P2 Uridine diphosphategalactose 566.055 644102 PubChem-compound Stachyose 1.0 Glucose 1-phosphate 56-73-5 CAS Alpha-Lactose 10542 PubChem-compound 17893 ChemSpider SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O HMDB0003345 HMDB H2O Water 18.010565 UDP-glucose 4-epimerase NADH BioCyc SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O NAD BioCyc 1.0 CPD-169 BioCyc 1.0 C05796 KEGG Compound 1.0 SMILES OCC(O)CO 1.0 D-Mannose 2.0 SUCROSE BioCyc Alpha-Lactose CPD-535 BioCyc CHEBI:16813 ChEBI SMILES OC[C@H]1O[C@H](O[P@@](O)(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@@H](O)[C@H]1O MANNOSE BioCyc 11850 PubChem-compound UDP-GLACTOSE BioCyc 63-42-3 CAS Sucrose SubPathwayInput 56-81-5 CAS 656504 PubChem-compound SMILES O P35575 UniProt C12H22O11 Melibiose 342.1162 Pyrophosphate Glycerol Q14376 UniProt 439709 PubChem-compound HMDB0000538 HMDB GALACTOSE-1P BioCyc Amino Sugar Metabolism SubPathway Galactinol 1.0 C12H22O11 Galactinol 342.1162 HMDB0000302 HMDB Glycolysis SubPathway C6H14O6 Sorbitol 182.07904 CHEBI:15846 ChEBI ADP BioCyc Lactase-phlorizin hydrolase HMDB0000660 HMDB Lysosome UDP-glucose 4-epimerase HMDB0001401 HMDB Glucose-6-phosphatase Beta-1,4-galactosyltransferase 1 CHEBI:16908 ChEBI Galactinol 1.0 C6H12O6 myo-Inositol 180.06339 Galactitol CHEBI:15713 ChEBI O4P Phosphate 94.95342 5988 PubChem-compound 1.0 Lysosomal alpha-glucosidase Fructose and Mannose Degradation SubPathway 1.0 SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O Galactosemia 87-89-8 CAS CPD-458 BioCyc Reaction833 false Adenosine triphosphate + D-Galactose → Adenosine diphosphate + Galactose 1-phosphate LEFT_TO_RIGHT CHEBI:397485 ChEBI HMDB0000211 HMDB 570889 ChemSpider 58-68-4 CAS ReactionCatalysis1401 ACTIVATION C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc ReactionCatalysis1400 ACTIVATION C9H15N2O15P3 Uridine triphosphate 483.96854 SMP0000040 SMPDB 1.0 ReactionCatalysis1403 ACTIVATION 585-99-9 CAS ReactionCatalysis1402 ACTIVATION ReactionCatalysis1405 ACTIVATION SMILES [O-]P([O-])([O-])=O ReactionCatalysis1404 ACTIVATION CHEBI:36219 ChEBI ReactionCatalysis1406 ACTIVATION 1.0 SMP0000045 SMPDB GO:0005764 GENE ONTOLOGY C6H12O6 D-Glucose 180.06339 D-Galactose UTP--glucose-1-phosphate uridylyltransferase CHEBI:67119 ChEBI GLC BioCyc HMDB0001429 HMDB ReactionCatalysis1408 ACTIVATION SMILES O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O Liver Galactinol SubPathwayOutput HMDB0000107 HMDB CHEBI:4208 ChEBI C3H8O3 Glycerol 92.04734 CHEBI:17924 ChEBI D-Galactose SMP0000182 SMPDB 439531 PubChem-compound O7P2 Pyrophosphate 173.91193 Uridine diphosphate glucose C21H29N7O14P2 NADH 665.12476 5958 PubChem-compound D-Glucose SMILES OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O 5957 PubChem-compound Hexokinase-1 P10253 UniProt C12H22O11 Sucrose 342.1162 Uridine triphosphate SMP0000064 SMPDB 530-26-7 CAS Galactose-1-phosphate uridylyltransferase CHEBI:15754 ChEBI SMILES OC[C@H]1OC(OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O C05399 KEGG Compound SMILES OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O HMDB0000122 HMDB Adenosine diphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 GO:0005615 GENE ONTOLOGY HMDB0000247 HMDB C6H14O6 Galactitol 182.07904 P36871 UniProt 1.0 CHEBI:17925 ChEBI CHEBI:17505 ChEBI Beta-galactosidase false Galactan + Water → 2 D-Galactose LEFT_TO_RIGHT SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O CPD-8587 BioCyc Melibiose 76293 ChemSpider 5682 ChemSpider UDP BioCyc false D-Galactose + Glycerol ↔ Galactosylglycerol REVERSIBLE P19367 UniProt CHEBI:28645 ChEBI false Sucrose + Water → D-Fructose + D-Galactose LEFT_TO_RIGHT false Alpha-Lactose + Water → 2 D-Galactose LEFT_TO_RIGHT false Alpha-Lactose → D-Galactose + Melibiose LEFT_TO_RIGHT false Melibiose → 2 D-Galactose LEFT_TO_RIGHT false Stachyose → D-Galactose + Raffinose LEFT_TO_RIGHT C6H13O9P Glucose 6-phosphate 260.02972 false Raffinose → D-Galactose + Sucrose LEFT_TO_RIGHT 14000-31-8 CAS 470-55-3 CAS false D-Galactose + D-Mannose ↔ Epimelibiose REVERSIBLE false D-Galactose + myo-Inositol ↔ Galactinol REVERSIBLE 440658 PubChem-compound CHEBI:17992 ChEBI 440656 PubChem-compound Phosphoglucomutase-1 440655 PubChem-compound 1.0 false D-Galactose + Sorbitol ↔ Melibiitol REVERSIBLE PW000200 PathWhiz GALACTOSE BioCyc CHEBI:15422 ChEBI 5589 ChemSpider Homo sapiens 17296-19-4 CAS 388299 ChemSpider Reaction1671 false Uridine diphosphategalactose → Galactinol LEFT_TO_RIGHT C6H12O6 D-Galactose 180.06339 Reaction1670 false Alpha-D-Glucose + D-Galactose → Alpha-Lactose + Water LEFT_TO_RIGHT 439451 PubChem-compound C05400 KEGG Compound Glucose 6-phosphate SubPathwayInput Water CHEBI:17973 ChEBI 1.0 5576 ChemSpider C00984 KEGG Compound SMILES OC[C@H]1O[C@@](CO)(OC2O[C@H](COC3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O CHEBI:16761 ChEBI SMILES OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO[C@H]3O[C@H](CO[C@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O false D-Galactose + NAD → Galactitol + NADH LEFT_TO_RIGHT GLC-6-P BioCyc 17069 ChemSpider CHEBI:27527 ChEBI false Adenosine triphosphate + Alpha-D-Glucose → Adenosine diphosphate + Glucose 6-phosphate LEFT_TO_RIGHT false Glucose 1-phosphate → Glucose 6-phosphate LEFT_TO_RIGHT Raffinose false Alpha-D-Glucose + Phosphate → Glucose 6-phosphate + Water LEFT_TO_RIGHT Reaction1664 false Uridine diphosphategalactose → Uridine diphosphate glucose LEFT_TO_RIGHT Melibiitol false Pyrophosphate + Uridine diphosphate glucose → Glucose 1-phosphate + Uridine triphosphate LEFT_TO_RIGHT Reaction1662 false D-Glucose + Uridine diphosphategalactose → Alpha-Lactose + Uridine 5'-diphosphate LEFT_TO_RIGHT false Glucose 1-phosphate + Uridine diphosphategalactose → Galactose 1-phosphate + Uridine diphosphate glucose LEFT_TO_RIGHT 9606 TAXONOMY Sucrose PW000146 PathWhiz PW000025 PathWhiz 5893 PubChem-compound 1.0 439357 PubChem-compound Reaction311 false Adenosine triphosphate + Alpha-D-Glucose → Adenosine diphosphate + Glucose 6-phosphate LEFT_TO_RIGHT CHEBI:15377 ChEBI C01613 KEGG Compound 1.0 18950 PubChem-compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 1.0 79025 PubChem-compound PW000008 PathWhiz CHEBI:4808 ChEBI 5793 PubChem-compound CHEBI:17522 ChEBI SMILES OCC(O)CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)COC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O Aldose reductase 512-69-6 CAS NAD SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@H]1O ReactionCatalysis1389 ACTIVATION SMILES OC[C@H]1O[C@H](OC[C@H]2O[C@H](O)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@@H](O)[C@@H]1O 10102 ChemSpider ReactionCatalysis1388 ACTIVATION ReactionCatalysis1387 ACTIVATION 63-39-8 CAS 1061 PubChem-compound 1.0 Q16851 UniProt 5780 PubChem-compound 57-50-1 CAS CHEBI:17659 ChEBI ReactionCatalysis1391 ACTIVATION ReactionCatalysis1390 ACTIVATION P06280 UniProt SMILES OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O HMDB0000645 HMDB 1.0 ReactionCatalysis1393 ACTIVATION ReactionCatalysis1392 ACTIVATION Galactan ReactionCatalysis1395 ACTIVATION ReactionCatalysis1394 ACTIVATION ReactionCatalysis1397 ACTIVATION C14H26O11 Galactan 370.14752 ReactionCatalysis1396 ACTIVATION ReactionCatalysis1398 ACTIVATION