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CAD protein CAD protein CAD protein Dihydroorotate dehydrogenase (quinone), mitochondrial Uridine monophosphate synthetase isoform A Uridine monophosphate synthetase isoform A Soluble calcium- activated nucleotidase 1 UMP-CMP kinase 2, mitochondrial Nucleoside diphosphate kinase 6 Soluble calcium- activated nucleotidase 1 GTP:AMP phosphotransferase, mitochondrial Inosine triphosphate pyrophosphatase CTP synthase 1 Soluble calcium- activated nucleotidase 1 Nucleoside diphosphate kinase 6 Soluble calcium- activated nucleotidase 1 UMP-CMP kinase 2, mitochondrial Cytosolic purine 5'-nucleotidase Guanine deaminase Cytosolic purine 5'-nucleotidase Uridine phosphorylase 2 Dihydropyrimidine dehydrogenase [NADP(+)] Dihydropyrimidinase Beta- ureidopropionase Ribonucleoside- diphosphate reductase large subunit Nucleoside diphosphate kinase 6 UMP-CMP kinase 2, mitochondrial Cytosolic purine 5'-nucleotidase Uridine- cytidine kinase-like 1 Cytidine deaminase Thymidine phosphorylase Deoxycytidylate deaminase Thymidine kinase, cytosolic Thymidylate synthase Thymidylate synthase Soluble calcium- activated nucleotidase 1 Nucleoside diphosphate kinase 6 Soluble calcium- activated nucleotidase 1 Cytosolic purine 5'-nucleotidase Thymidine kinase, cytosolic Thymidine phosphorylase Dihydropyrimidine dehydrogenase [NADP(+)] Dihydropyrimidinase Beta- ureidopropionase Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial Nucleoside diphosphate kinase 6 Thymidylate synthase Ribonucleoside- diphosphate reductase large subunit Uridine- cytidine kinase-like 1 Beta- ureidopropionase Uridine triphosphate Cytidine triphosphate Uridine 5'-diphosphate CDP dCTP Thymidine 5'-triphosphate β-Alanine L-Glutamine Carbamoyl phosphate Phosphoribosyl pyrophosphate 3- Aminoisobutanoic acid ATP H 2 O Hydrogen carbonate ADP P i Ureidosuccinic acid L-Dihydroorotic acid Quinone Orotic acid Orotidylic acid Uridine 5'-monophosphate H 2 O P i ATP ADP ADP ATP H 2 O P i ADP AMP H 2 O PP i ATP ADP P i dCTP H 2 O P i ADP ATP H 2 O Cytidine monophosphate P i ADP ATP H 2 O Cytidine P i H 2 O Uridine NH 3 H 2 O P i P i Accumulation Uracil Ribose 1-phosphate NADP Dihydrouracil NADPH H 2 O Ureidopropionic acid H 2 O NH 3 CO 2 H 2 O dCDP ATP ADP dCMP ATP ADP H 2 O Deoxycytidine P i ATP ADP H 2 O Accumulation Deoxyuridine NH 3 P i Deoxyribose 1-phosphate H 2 O dUMP NH 3 ATP ADP 5,10-Methylene-THF 5-Thymidylic acid Dihydrofolic acid ATP dTDP ADP H 2 O P i ATP ADP H 2 O P i H 2 O Accumulation Thymidine P i