Guanosine diphosphate
Gβ
Guanine nucleotide-binding protein G(T) subunit gamma-T1
cAMP-dependent protein kinase catalytic subunit beta
CPD-8587
BioCyc
Ethylene-responsive transcription factor ESR1
C00035
KEGG Compound
ReactionCatalysis1841
ACTIVATION
1.0
ReactionCatalysis1845
ACTIVATION
cAMP-dependent protein kinase catalytic subunit beta
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
ReactionCatalysis1844
ACTIVATION
1.0
Adenosine triphosphate
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
HMDB0000250
HMDB
SMILES
[O-]P([O-])(=O)OP([O-])([O-])=O
14000-31-8
CAS
Guanine nucleotide-binding protein G(T) subunit gamma-T1
1.0
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Pyrophosphate
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Phosphate
HMDB0000538
HMDB
C00044
KEGG Compound
Ethylene-responsive transcription factor ESR1
ATP
BioCyc
1.0
P63092
UniProt
559142
ChemSpider
Cytoplasm
PW000448
PathWhiz
P01215
UniProt
Guanine nucleotide-binding protein gamma-beta
C10H12N5O6P
cAMP
329.05252
1.0
cAMP-dependent protein kinase catalytic subunit beta
cAMP
CHEBI:15422
ChEBI
Q08462
UniProt
1.0
Homo sapiens
P62136
UniProt
Glycoprotein hormones alpha chain
SubPathwayControl688
SubPathway688Control
ActivatingSubPathwayControl
5742
ChemSpider
Glycoprotein hormones alpha chain
SubPathwayActivator
C00575
KEGG Compound
2.7.11.11
false
2.7.11.11
Cyclic AMP-responsive element-binding protein 1 → Cyclic AMP-responsive element-binding protein 1 + Phosphate
LEFT_TO_RIGHT
1.0
4.6.1.1
false
4.6.1.1
Adenosine triphosphate → Pyrophosphate + cAMP
LEFT_TO_RIGHT
Reaction2129
false
Follicle-stimulating hormone receptor bound to G protein complex + Guanosine triphosphate → Follicle-stimulating hormone receptor + Guanine nucleotide-binding protein alpha + Guanine nucleotide-binding protein gamma-beta + Guanosine diphosphate
LEFT_TO_RIGHT
SubPathwayInteraction693
SubPathway693Reaction
SubPathwayReaction
Reaction2127
true
Adenylate cyclase type 2 + Guanine nucleotide-binding protein alpha → Adenylate cyclase bound to G(s) subunit alpha
LEFT_TO_RIGHT
SubPathwayInteraction694
SubPathway694Reaction
SubPathwayReaction
Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone
1.0
1.0
SubPathwayInteraction692
SubPathwayReaction
SubPathway692Reaction
C10H16N5O13P3
Adenosine triphosphate
506.99576
O4P
Phosphate
94.95342
8977
PubChem-compound
5851
ChemSpider
6830
PubChem-compound
C10H15N5O11P2
Guanosine diphosphate
443.02432
SMILES
NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O
PPI
BioCyc
1.0
ReactionCatalysis1992
ACTIVATION
9606
TAXONOMY
C10H16N5O14P3
Guanosine triphosphate
522.99066
Guanosine triphosphate
P62873
UniProt
Follicle-stimulating hormone receptor
Adenylate cyclase type 2
8630
ChemSpider
HMDB0000058
HMDB
SMILES
[O-]P([O-])([O-])=O
GO:0005886
GENE ONTOLOGY
Adenylate cyclase bound to G(s) subunit alpha
2.7.11.11
false
2.7.11.11
cAMP → cAMP + cAMP-dependent protein kinase catalytic subunit beta
LEFT_TO_RIGHT
Cell Membrane
1.0
C00009
KEGG Compound
Cyclic AMP-responsive element-binding protein 1
14265-44-2
CAS
6569
ChemSpider
HMDB0001429
HMDB
SMILES
NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
1.0
P22694
UniProt
CHEBI:18361
ChEBI
CHEBI:17552
ChEBI
SMILES
NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1
GTP
BioCyc
P63211
UniProt
CHEBI:18367
ChEBI
Follicle-stimulating hormone receptor
1032
ChemSpider
C00002
KEGG Compound
P16220
UniProt
P23945
UniProt
GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE
BioCyc
SMP0000333
SMPDB
GO:0005634
GENE ONTOLOGY
Adenylate cyclase type 2
HMDB0001273
HMDB
Follicle-stimulating hormone activation of follicle-stimulating hormone receptor bound to G protein complex
ActivatingSubPathway
CHEBI:17489
ChEBI
644102
PubChem-compound
CAMP
BioCyc
ReactionCatalysis1816
ACTIVATION
SMILES
NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1
1.0
1.0
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
C00013
KEGG Compound
Extracellular Space
HMDB0001201
HMDB
2.7.11.11
false
2.7.11.11
Ethylene-responsive transcription factor ESR1 → Ethylene-responsive transcription factor ESR1 + Phosphate
LEFT_TO_RIGHT
O7P2
Pyrophosphate
173.91193
Cyclic AMP-responsive element-binding protein 1
1.0
5957
PubChem-compound
Gonad Development
SubPathway
Q9SAD4
UniProt
Gamete Generation in Females
SubPathway
3.1.3.16
false
3.1.3.16
Cyclic AMP-responsive element-binding protein 1 + Phosphate → Cyclic AMP-responsive element-binding protein 1
LEFT_TO_RIGHT
Spermatogenesis in Males
SubPathway
1.0
3.1.3.16
false
3.1.3.16
Ethylene-responsive transcription factor ESR1 + Phosphate → Ethylene-responsive transcription factor ESR1
LEFT_TO_RIGHT
86-01-1
CAS
1.0
Nucleus
Follicle-stimulating hormone receptor bound to G protein complex
SubPathwayActivation
1061
PubChem-compound
6076
PubChem-compound
1.0
CHEBI:15996
ChEBI
Gβ
56-65-5
CAS
ReactionCatalysis1834
ACTIVATION
GO:0005615
GENE ONTOLOGY
1.0
GO:0005737
GENE ONTOLOGY
146-91-8
CAS
60-92-4
CAS
Q9UBI6
UniProt
cAMP
SubPathwayInput