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Sodium channel protein type 10 subunit alpha Sodium channel subunit beta-1 Cytochrome P450 1A2 Cytochrome P450 3A4 Cytochrome P450 1A2 Cytochrome P450 3A4 Alpha-1A adrenergic receptor 5- hydroxytryptamine receptor 1A D(1A) dopamine receptor Beta-endorphin Mu-type opioid receptor Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit alpha-4 Voltage- dependent P/Q-type calcium channel subunit alpha-1A Voltage- dependent L-type calcium channel subunit beta-1 Voltage- dependent calcium channel subunit alpha-2/delta-2 Sodium channel protein type 10 subunit alpha Sodium channel subunit beta-1 Potassium voltage-gated channel subfamily D member 2 Kv channel- interacting protein 2 Beta-endorphin Glutamate [NMDA] receptor subunit zeta-1 Glutamate [NMDA] receptor subunit epsilon-1 Glutamate [NMDA] receptor subunit 3A Sodium- dependent noradrenaline transporter Sodium- dependent serotonin transporter Sodium- dependent dopamine transporter Pro- opiomelanocortin Neuroendocrine convertase 2 Sodium/potassium- transporting ATPase subunit alpha-1 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Sodium/potassium- transporting ATPase subunit gamma Lidocaine Lidocaine 2,6-Dimethylaniline Monoethylglycinexylidide Glycinexylidide 2-Amino-3-methylbenzoate 4-Hydroxy-2,6-dimethylaniline 3-Hydroxylidocaine 3- Hydroxymonoethylglycinexylidide O 2 NADPH H + H 2 O NADP O 2 NADH H 2 O Formaldehyde NAD Heme Heme Heme Heme Norepinephrine Serotonin Dopamine Ca + Ca + Na + Na + K + K + Ca + Ca + Na + K + Ca + Ca + Norepinephrine Serotonin Na + Na + Na + Na + Dopamine Na + Na + ATP H 2 O Na + K + ADP P i Na + K + Axon Voltage-gated sodium channel (INa) Synaptic Vesicle