Quantitative metabolomics services for biomarker discovery and validation.
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Ca+ Na+ Ca+ Ca+ Na+ K+ K+ Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit alpha-3 Dimethylaniline monooxygenase [N-oxide- forming] 3 UDP- glucuronosyltransferase 1-4 UDP- glucuronosyltransferase 1-9 Cytochrome P450 2A6 Cytochrome P450 2B6 Aldehyde oxidase Cytochrome P450 2A6 UDP- glucuronosyltransferase 1-4 UDP- glucuronosyltransferase 1-9 Cytochrome P450 2A6 Alpha-1A adrenergic receptor 5- hydroxytryptamine receptor 1A D(1A) dopamine receptor Beta-endorphin Mu-type opioid receptor Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit alpha-4 Voltage- dependent P/Q-type calcium channel subunit alpha-1A Voltage- dependent L-type calcium channel subunit beta-1 Voltage- dependent calcium channel subunit alpha-2/delta-2 Potassium voltage-gated channel subfamily D member 2 Kv channel- interacting protein 2 Beta-endorphin Glutamate [NMDA] receptor subunit zeta-1 Glutamate [NMDA] receptor subunit epsilon-1 Glutamate [NMDA] receptor subunit 3A Sodium- dependent noradrenaline transporter Sodium- dependent serotonin transporter Sodium- dependent dopamine transporter Pro- opiomelanocortin Neuroendocrine convertase 2 Sodium/potassium- transporting ATPase subunit alpha-1 Nicotine Nicotine Nicotine Nornicotine Norcotinine Hydroxycotinine trans-3-Hydroxycotinine glucuronide Cotinine Cotinine N-oxide 5'-Hydroxycotinine O2 NADPH H+ Nicotine-1'-N-oxide H2O NADP Uridine diphosphate glucuronic acid Nicotine glucuronide Uridine 5'-diphosphate Nicotine imine H+ H2O O2 H2O"="">2 H+ O2 NADPH H+ H2O NADP Uridine diphosphate glucuronic acid Cotinine glucuronide Uridine 5'-diphosphate O2 NADH H2O Formaldehyde NAD FAD Heme Heme FAD Molybdopterin 2Fe-2S Heme Heme Norepinephrine Serotonin Dopamine Ca+ Na+ K+ Ca+ Ca+ Norepinephrine Serotonin Na+ Na+ Na+ Na+ Dopamine Na+ Na+ ATP H2O Na+ K+ ADP Pi Na+ K+ Sodium channel protein type 10 subunit alpha Neuronal acetylcholine receptor subunit alpha-4 Sodium channel subunit beta-1 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit gamma Neuronal acetylcholine receptor subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Dendrite Synaptic Vesicle Presynaptic Neuron Postsynaptic Neuron Synaptic Cleft Neuron Neuron Axon Action Potential Membrane Potential (mV) Resting Potential -70 Time +40 0 Depolarization Peak Action Potential Repolarization Hyperpolarization