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7722-84-1 CAS C00314 KEGG Compound 1.0 937 ChemSpider CHEBI:16134 ChEBI Sphingolipid Metabolism SubPathway HMDB0003125 HMDB Valine, Leucine, and Isoleucine Degradation SubPathway SMILES O SMILES OO CHEBI:28803 ChEBI H3N Ammonia 17.026548 2.7.1.35 false 2.7.1.35 Phosphoric acid + Pyridoxine → Pyridoxine 5'-phosphate + Water LEFT_TO_RIGHT Reaction1015 false 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate → 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate LEFT_TO_RIGHT Reaction1016 false Glycolaldehyde → Pyridoxine LEFT_TO_RIGHT 1.0 Reaction1014 false 4-Pyridoxic acid → 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate LEFT_TO_RIGHT 1.0 DIHYDROXYPHENYLGLYCOLALDEHYDE BioCyc 1004 PubChem-compound Q9NVS9 UniProt PW000051 PathWhiz Pyridoxamine 5'-phosphate 66-72-8 CAS Pyridoxamine C8H11NO3 Pyridoxine 169.0739 1026 ChemSpider 1025 ChemSpider 1024 ChemSpider 6723 PubChem-compound 1023 ChemSpider PW000042 PathWhiz 1022 ChemSpider 1021 ChemSpider 1.0 952 ChemSpider GO:0005829 GENE ONTOLOGY PYRIDOXAL_PHOSPHATE BioCyc C8H9NO4 4-Pyridoxic acid 183.05316 Ammonia PW000158 PathWhiz PW000157 PathWhiz 2.0 C8H12N2O2 Pyridoxamine 168.08987 CHEBI:16240 ChEBI PW000152 PathWhiz 1.0 Reaction1022 false Pyridoxal 5'-phosphate + Water → Phosphoric acid + Pyridoxal LEFT_TO_RIGHT Reaction1023 false Phosphoric acid + Pyridoxamine ← Pyridoxamine 5'-phosphate + Water RIGHT_TO_LEFT Reaction1021 false Pyridoxine 5'-phosphate + Water → Phosphoric acid + Pyridoxine LEFT_TO_RIGHT 529-96-4 CAS Hypophosphatasia ReactionCatalysis631 ACTIVATION CPD-455 BioCyc Cytosol 4-Pyridoxic acid CPD-6641 BioCyc 1.0 217 ChemSpider SMILES CC1=NC=C(CO)C(C(O)=O)=C1O PYRIDOXAMINE-5P BioCyc HMDB0001545 HMDB 7664-38-2 CAS ReactionCatalysis626 ACTIVATION SubPathwayInteraction111 SubPathway111Reaction SubPathwayReaction SubPathwayInteraction110 SubPathway110Reaction SubPathwayReaction C00009 KEGG Compound C00007 KEGG Compound Pyridoxal phosphate phosphatase SubPathwayInteraction106 SubPathwayReaction SubPathway106Reaction C04604 KEGG Compound SubPathwayInteraction105 SubPathwayReaction SubPathway105Reaction Pyridoxine 5'-phosphate SubPathwayInteraction108 SubPathwayReaction SubPathway108Reaction SubPathwayInteraction107 SubPathway107Reaction SubPathwayReaction C00001 KEGG Compound SubPathwayInteraction109 SubPathway109Reaction SubPathwayReaction SMILES CC1=C(O)C(CN)=C(CO)C=N1 141-46-8 CAS Glycolaldehyde HMDB0001431 HMDB Pyridoxine HMDB0001555 HMDB C00250 KEGG Compound C2H4O2 Glycolaldehyde 60.02113 ReactionCatalysis619 ACTIVATION 7664-41-7 CAS Phenylalanine and Tyrosine Metabolism SubPathway Gluconeogenesis SubPathway Tyrosine Metabolism SubPathway Glycine and Serine Metabolism SubPathway ReactionCatalysis652 ACTIVATION C00018 KEGG Compound ReactionCatalysis650 ACTIVATION CHEBI:18335 ChEBI SMP0000503 SMPDB HMDB0001319 HMDB C8H12NO6P Pyridoxine 5'-phosphate 249.04022 222 PubChem-compound 440403 PubChem-compound C00014 KEGG Compound Extracellular Space 1.0 SMILES OP(O)(O)=O HMDB0000239 HMDB Aldehyde oxidase ReactionCatalysis647 ACTIVATION CHEBI:16709 ChEBI Alkaline phosphatase, tissue-nonspecific isozyme C8H10NO6P Pyridoxal 5'-phosphate 247.02457 C00027 KEGG Compound Pyridoxal PYRIDOXAL BioCyc C00266 KEGG Compound CHEBI:26078 ChEBI 54-47-7 CAS GO:0005615 GENE ONTOLOGY 1.0 ReactionCatalysis638 ACTIVATION PYRIDOXAMINE BioCyc Porphyrin Metabolism SubPathway CHEBI:16410 ChEBI SMP0000128 SMPDB SMP0000008 SMPDB 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate SMP0000006 SMPDB Pyridoxine-5'-phosphate oxidase SMILES CC1=NC=C(COP(O)(O)=O)C(CO)=C1O SMILES CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O HMDB0000017 HMDB HYDROGEN-PEROXIDE BioCyc SMP0000004 SMPDB 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxine ← Hydrogen peroxide + Pyridoxal RIGHT_TO_LEFT 389728 ChemSpider 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxine 5'-phosphate ← Hydrogen peroxide + Pyridoxal 5'-phosphate RIGHT_TO_LEFT 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxamine + Water → Ammonia + Hydrogen peroxide + Pyridoxal LEFT_TO_RIGHT 1.4.3.5 false 1.4.3.5 Oxygen + Pyridoxamine 5'-phosphate + Water → Ammonia + Hydrogen peroxide + Pyridoxal 5'-phosphate LEFT_TO_RIGHT ReactionCatalysis664 ACTIVATION ReactionCatalysis662 ACTIVATION ReactionCatalysis660 ACTIVATION C00847 KEGG Compound 756 PubChem-compound Pyridoxal phosphate phosphatase Pyridoxal kinase 440898 PubChem-compound 65-23-6 CAS 763 ChemSpider CHEBI:17071 ChEBI ReactionCatalysis656 ACTIVATION ReactionCatalysis657 ACTIVATION ReactionCatalysis654 ACTIVATION 784 PubChem-compound Homo sapiens Pyridoxal 5'-phosphate SubPathwayInput 85-87-0 CAS Transport48 false Pyridoxamine (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT Transport47 false Pyridoxal (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell, Cytosol LEFT_TO_RIGHT 7732-18-5 CAS 82-82-6 CAS Pyridoxal kinase O2 Oxygen 31.98983 C8H9NO3 Pyridoxal 167.05824 AMMONIA BioCyc SMILES N Pyridoxamine 1.0 SMP0000024 SMPDB Water CHEBI:17978 ChEBI Phosphoric acid C00627 KEGG Compound Q96GD0 UniProt 2.0 7782-44-7 CAS HMDB0001377 HMDB C8H13N2O5P Pyridoxamine 5'-phosphate 248.05621 1.0 C8H7NO5 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate 197.03242 C8H7NO4 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate 181.0375 C06050 KEGG Compound SMP0000034 SMPDB HMDB0001491 HMDB 1.0 SMILES CC1=C(O)C(CO)=C(CO)C=N1 SMP0000032 SMPDB 9606 TAXONOMY 962 PubChem-compound 1050 PubChem-compound 1051 PubChem-compound CPD-1112 BioCyc 1052 PubChem-compound PW000142 PathWhiz 1.0 1.0 PW000148 PathWhiz 979 ChemSpider Hydrogen peroxide 736 ChemSpider 1053 PubChem-compound 1054 PubChem-compound 1055 PubChem-compound SMILES CC1=NC=C(CO)C(C=O)=C1O SMILES O=O H3O4P Phosphoric acid 97.9769 Pyridoxal phosphate phosphatase HMDB0006954 HMDB HMDB0006955 HMDB HMDB0000051 HMDB HMDB0002111 HMDB CHEBI:15377 ChEBI C00647 KEGG Compound CHEBI:15379 ChEBI CHEBI:18405 ChEBI 1.0 Q06278 UniProt Pyridoxine-5'-phosphate oxidase CHEBI:17310 ChEBI 1.0 Pyridoxal kinase Oxygen SMILES CC1=NC=C(C=O)C(C(O)=O)=C1O SMILES CC1=NC=C(C(O)=O)C(C(O)=O)=C1O SMILES CC1=NC=C(COP(O)(O)=O)C(CN)=C1O 447-05-2 CAS O00764 UniProt P05186 UniProt C00534 KEGG Compound Aldehyde oxidase CHEBI:17405 ChEBI PYRIDOXINE-5P BioCyc 1.0 H2O Water 18.010565 1.0 H2O2 Hydrogen peroxide 34.005478 Alkaline phosphatase, tissue-nonspecific isozyme 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate HMDB0003344 HMDB PW000479 PathWhiz 977 PubChem-compound 6467 ChemSpider 389354 ChemSpider Pyridoxal SMILES OCC=O Reaction102 false Oxygen + Pyridoxal + Water → 4-Pyridoxic acid + Hydrogen peroxide LEFT_TO_RIGHT 2.7.1.35 false 2.7.1.35 Phosphoric acid + Pyridoxamine → Pyridoxamine 5'-phosphate + Water LEFT_TO_RIGHT 3.1.3.1 false 3.1.3.1 Pyridoxal 5'-phosphate + Water ← Phosphoric acid + Pyridoxal RIGHT_TO_LEFT HMDB0002142 HMDB Alkaline phosphatase, tissue- nonspecific isozyme Pyridoxine- 5'-phosphate oxidase Aldehyde oxidase Pyridoxine- 5'-phosphate oxidase Pyridoxal kinase Pyridoxal kinase Pyridoxal kinase Pyridoxine- 5'-phosphate oxidase Pyridoxine- 5'-phosphate oxidase Alkaline phosphatase, tissue- nonspecific isozyme Pyridoxal phosphate phosphatase Pyridoxal phosphate phosphatase Pyridoxal phosphate phosphatase Pyridoxal 5'-phosphate Pyridoxal Pyridoxal Pyridoxamine Pyridoxamine Pyridoxal 5'-phosphate H 2 O P i H 2 O O 2 NH 3 H 2 O 2 O 2 H 2 O 4-Pyridoxic acid H 2 O 2 2-Methyl-3- hydroxy-5- formylpyridine- 4-carboxylate 3-Hydroxy-2- methylpyridine- 4,5- dicarboxylate Glycolaldehyde