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C5H8O4 autoinducer 2 132.04225 247 PubChem-compound 454-29-5 CAS C5H8O4 (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one 132.04225 C02739 KEGG Compound C5H10O5 (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran 150.05283 6022 PubChem-compound C5H7O7P (4S)-4-hydroxy-2,3-pentanedione 5-phosphate 209.99403 C5H7O7P 3-hydroxy-2,4-pentanedione 5-phosphate 209.99403 C23H38N7O17P3S Acetyl-CoA 809.1258 937 ChemSpider autoinducer-2 kinase HMDB00250 HMDB 1.0 HMDB01341 HMDB C05330 KEGG Compound AI-2 transport protein TqsA 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase SMILES O 1.0 C5H11NO2 Betaine 117.07898 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2.0 (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran CHEBI:17230 ChEBI Autoinducer 2 import system permease protein lsrD ATP BioCyc 1.0 HMDB01473 HMDB P64461 UniProt 25200942 PubChem-compound 1.0 3-hydroxy-2,4-pentadione 5-phosphate thiolase Dihydroxyacetone phosphate 54758622 PubChem-compound 6816 PubChem-compound C3H7O6P Dihydroxyacetone phosphate 169.99803 242 ChemSpider 1009 PubChem-compound 559142 ChemSpider ADP BioCyc 3-hydroxy-2,4-pentadione 5-phosphate thiolase Quorum Sensing CHEBI:8968 ChEBI phospho-AI-2 isomerase HMDB00939 HMDB 49791978 PubChem-compound Transport376 false (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Extracellular Space LEFT_TO_RIGHT Transport375 false (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Periplasmic Space LEFT_TO_RIGHT C15H23N6O5S S-Adenosylmethionine 399.14505 1.0 HMDB01206 HMDB 1.0 5742 ChemSpider 1038 PubChem-compound AI-2 ABC transporter - ATP binding subunit A GO:0005829 GENE ONTOLOGY Betaine HMDB59597 HMDB 107-43-7 CAS PW000837 PathWhiz PW000836 PathWhiz SMP00856 SMPDB SMP00857 SMPDB ADENOSYL-HOMO-CYS BioCyc 1.0 CHEBI:71316 ChEBI Acetyl-CoA CHEBI:71677 ChEBI 1010 ChemSpider GO:0070258 GENE ONTOLOGY SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Adenine PPI BioCyc C5H5N5 Adenine 135.05449 1.0 BiologicalState109 CHEBI:44800 ChEBI HMDB01423 HMDB Hydrogen Ion 979-92-0 CAS C00111 KEGG Compound SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12 C15H26N5O20P4 Phosphoribosyl-ATP 720.01215 Cytosol C14H20N6O5S S-Adenosylhomocysteine 384.12158 Adenosine triphosphate Autoinducer-2 ABC transporter - periplasmic binding protein B Hydrogen Ion 1.0 Phosphoribosyl-ATP C00008 KEGG Compound CHEBI:15414 ChEBI ADENINE BioCyc C00001 KEGG Compound CHEBI:18361 ChEBI phospho-AI-2 isomerase 673 PubChem-compound Inner Membrane 3-hydroxy-2,4-pentadione 5-phosphate thiolase C00002 KEGG Compound ReactionCatalysis3039 ACTIVATION 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase AI-2 transport protein TqsA Autoinducer-2 ABC transporter - periplasmic binding protein B SMILES NC1=C2NC=NC2=NC=N1 AI-2 ABC transporter - ATP binding subunit A autoinducer-2 kinase 1.0 57-04-5 CAS ReactionCatalysis3038 ACTIVATION C00019 KEGG Compound ReactionCatalysis3040 ACTIVATION ReactionCoupledTransportCatalysis158 ACTIVATION ReactionCatalysis3041 ACTIVATION 1.0 S-ADENOSYLMETHIONINE BioCyc C00010 KEGG Compound Extracellular Space C00013 KEGG Compound O7P2 Pyrophosphate 173.91193 S-ribosylhomocysteine lyase 5957 PubChem-compound GO:0005620 GENE ONTOLOGY ReactionCatalysis3042 ACTIVATION SMILES NC(CCS)C(O)=O CHEBI:16708 ChEBI 562 TAXONOMY SMILES [H][C@@](O)(CO)C(=O)C(C)=O (4S)-4-hydroxy-2,3-pentanedione 5-phosphate H Hydrogen Ion 1.007825 3-hydroxy-2,4-pentanedione 5-phosphate 388301 ChemSpider S-Adenosylhomocysteine S-ribosyl-L-homocysteine autoinducer 2 (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one autoinducer-2 ABC transporter (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran C00021 KEGG Compound 56-65-5 CAS C00147 KEGG Compound C00024 KEGG Compound P45578 UniProt Adenosine diphosphate Dimethylglycine GO:0005615 GENE ONTOLOGY Autoinducer 2 import system permease protein lsrC C10H15N5O10P2 Adenosine diphosphate 427.02942 1.0 1.0 1118-68-9 CAS ReactionCoupledTransport124 false (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + Phosphoribosyl-ATP + Water → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + Adenosine diphosphate + Hydrogen Ion + Pyrophosphate LEFT_TO_RIGHT 73-24-5 CAS C9H14NO6S S-ribosyl-L-homocysteine 264.05417 1.0 C4H9NO2 Dimethylglycine 103.06333 1.0 HMDB00092 HMDB (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran HMDB01185 HMDB CHEBI:1146900 ChEBI Water 653 ChemSpider 1.0 C00719 KEGG Compound C5H8O4 4,5-Dihydroxy-2,3-pentanedione 132.04225 P77257 UniProt SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS S-adenosyl-L-methionine biosynthesis SubPathway P0AF12 UniProt CO-A BioCyc 72-89-9 CAS 648 ChemSpider CHEBI:17750 ChEBI SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 HMDB00538 HMDB ReactionCatalysis5893 ACTIVATION SMILES CN(C)CC(O)=O P76142 UniProt Water P0AFS1 UniProt P76143 UniProt CHEBI:15422 ChEBI P0AFS5 UniProt 6557 ChemSpider 668 PubChem-compound CHEBI:17724 ChEBI Autoinducer 2 import system permease protein lsrC SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS SubPathwayInteraction1187 SubPathwayReaction SubPathway1187Reaction C01026 KEGG Compound 1.0 SMILES C[N+](C)(C)CC([O-])=O 1.0 (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 DIHYDROXY-ACETONE-PHOSPHATE BioCyc CHEBI:18263 ChEBI S-ribosylhomocysteine lyase CHEBI:16761 ChEBI SMILES OCC(=O)COP(O)(O)=O 2.0 962 PubChem-compound DIMETHYL-GLYCINE BioCyc 31983 ChemSpider 10.0 5800 ChemSpider 392413 ChemSpider HMDB02111 HMDB C00080 KEGG Compound 1.0 BETAINE BioCyc Periplasmic Space 1.0 4.1.2.- false 4.1.2.- 3-hydroxy-2,4-pentanedione 5-phosphate + Coenzyme A → Acetyl-CoA + Dihydroxyacetone phosphate LEFT_TO_RIGHT C4H9NO2S Homocysteine 135.0354 CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] HMDB00742 HMDB CHEBI:16108 ChEBI 58-64-0 CAS Reaction3072 false (4S)-4-hydroxy-2,3-pentanedione 5-phosphate → 3-hydroxy-2,4-pentanedione 5-phosphate LEFT_TO_RIGHT 2.7.1.- false 2.7.1.- (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + Adenosine triphosphate → (4S)-4-hydroxy-2,3-pentanedione 5-phosphate + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Reaction3070 true (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + Water LEFT_TO_RIGHT Reaction5929 false S-ribosyl-L-homocysteine → 4,5-Dihydroxy-2,3-pentanedione + Homocysteine LEFT_TO_RIGHT S-Adenosylmethionine HOMO-CYS BioCyc Reaction3069 true autoinducer 2 → (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one LEFT_TO_RIGHT 4.4.1.21 false 4.4.1.21 S-ribosyl-L-homocysteine → Homocysteine + autoinducer 2 LEFT_TO_RIGHT 3.2.2.9 false 3.2.2.9 S-Adenosylhomocysteine + Water → S-ribosyl-L-homocysteine + Adenine LEFT_TO_RIGHT 1.0 Reaction3066 false Dimethylglycine + S-Adenosylmethionine → Betaine + Hydrogen Ion + S-Adenosylhomocysteine LEFT_TO_RIGHT 1.0 Autoinducer 2 import system permease protein lsrD 1.0 1.0 SMILES CC(=O)C(=O)C(O)CO 1.0 SMILES [N+]C(CCSCC1OC(O)C(O)C1O)C([O-])=O TransportCatalysis322 ACTIVATION TransportCatalysis321 ACTIVATION HMDB00034 HMDB SMILES CC(=O)C(O)C(=O)COP([O-])([O-])=O SMILES CC(=O)C(=O)C(O)COP([O-])([O-])=O SMILES CC1(O)OCC(O)C1(O)O SMILES CC1(O)OCC(O)C1=O HMDB03665 HMDB 644102 PubChem-compound 444493 PubChem-compound SMILES NC1=[N+](C=NC2=C1N=CN2C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O)C1OC(COP(O)(O)=O)C(O)C1O Pyrophosphate SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12)C(O)=O 757 ChemSpider (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran 25246222 PubChem-compound Homocysteine 1.0 ACETYL-COA BioCyc H2O Water 18.010565 1.0 190 PubChem-compound 4,5-Dihydroxy-2,3-pentanedione CHEBI:425228 ChEBI P77432 UniProt 29908-03-0 CAS CHEBI:16680 ChEBI CHEBI:15351 ChEBI 1.0 HMDB00043 HMDB 24762165 PubChem-compound 984 ChemSpider 185 ChemSpider Adenosine diphosphate 85-61-0 CAS B1XEA2 UniProt Transcriptional regulator LsrR AI-2 transport protein TqsA AI-2 transport protein TqsA 5'- methylthioadenosine/S- adenosylhomocysteine nucleosidase S- ribosylhomocysteine lyase autoinducer-2 kinase phospho-AI-2 isomerase 3-hydroxy- 2,4- pentadione 5-phosphate thiolase S- ribosylhomocysteine lyase Autoinducer 2 import system permease protein lsrC Autoinducer 2 import system permease protein lsrD AI-2 ABC transporter - ATP binding subunit A (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran S- Adenosylhomocysteine H 2 O Adenine S-ribosyl-L- homocysteine Homocysteine autoinducer 2 (2R,4S)-2- methyl-2,4- dihydroxydihydrofuran- 3-one H 2 O (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran ATP ADP H + (4S)-4- hydroxy-2,3- pentanedione 5-phosphate 3-hydroxy- 2,4- pentanedione 5-phosphate CoA Acetyl-CoA Dihydroxyacetone phosphate S- Adenosylmethionine Dimethylglycine H + Betaine S-ribosyl-L- homocysteine 4,5- Dihydroxy- 2,3- pentanedione Homocysteine (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran Phosphoribosyl- ATP H 2 O ADP H + PP i (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran 3-hydroxy- 2,4- pentanedione 5-phosphate 3-hydroxy- 2,4- pentanedione 5-phosphate 3-hydroxy- 2,4- pentanedione 5-phosphate S-adenosyl-L- methionine biosynthesis Autoinducer-2 ABC transporter - periplasmic binding protein B Transcription of lsrK,lsrR,lsrA,lsrC,lsrD,lsrB,lsrF,lsrG,tam,yneE
C5H8O4 autoinducer 2 132.04225 247 PubChem-compound 454-29-5 CAS C5H8O4 (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one 132.04225 C02739 KEGG Compound C5H10O5 (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran 150.05283 6022 PubChem-compound C5H7O7P (4S)-4-hydroxy-2,3-pentanedione 5-phosphate 209.99403 C5H7O7P 3-hydroxy-2,4-pentanedione 5-phosphate 209.99403 C23H38N7O17P3S Acetyl-CoA 809.1258 937 ChemSpider autoinducer-2 kinase HMDB00250 HMDB 1.0 HMDB01341 HMDB C05330 KEGG Compound AI-2 transport protein TqsA 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase SMILES O 1.0 C5H11NO2 Betaine 117.07898 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2.0 (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran CHEBI:17230 ChEBI Autoinducer 2 import system permease protein lsrD ATP BioCyc 1.0 HMDB01473 HMDB P64461 UniProt 25200942 PubChem-compound 1.0 3-hydroxy-2,4-pentadione 5-phosphate thiolase Dihydroxyacetone phosphate 54758622 PubChem-compound 6816 PubChem-compound C3H7O6P Dihydroxyacetone phosphate 169.99803 242 ChemSpider 1009 PubChem-compound 559142 ChemSpider ADP BioCyc 3-hydroxy-2,4-pentadione 5-phosphate thiolase Quorum Sensing CHEBI:8968 ChEBI phospho-AI-2 isomerase HMDB00939 HMDB 49791978 PubChem-compound Transport376 false (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Extracellular Space LEFT_TO_RIGHT Transport375 false (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Periplasmic Space LEFT_TO_RIGHT C15H23N6O5S S-Adenosylmethionine 399.14505 1.0 HMDB01206 HMDB 1.0 5742 ChemSpider 1038 PubChem-compound AI-2 ABC transporter - ATP binding subunit A GO:0005829 GENE ONTOLOGY Betaine HMDB59597 HMDB 107-43-7 CAS PW000837 PathWhiz PW000836 PathWhiz http://identifiers.org/smpdb/SMP00856 SMPDB http://identifiers.org/smpdb/SMP00857 SMPDB ADENOSYL-HOMO-CYS BioCyc 1.0 CHEBI:71316 ChEBI Acetyl-CoA CHEBI:71677 ChEBI 1010 ChemSpider GO:0070258 GENE ONTOLOGY SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Adenine PPI BioCyc C5H5N5 Adenine 135.05449 1.0 BiologicalState109 Escherichia coli, Inner Membrane CHEBI:44800 ChEBI HMDB01423 HMDB S-adenosyl-L-methionine biosynthesis SubPathway Hydrogen Ion 979-92-0 CAS C00111 KEGG Compound SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12 C15H26N5O20P4 Phosphoribosyl-ATP 720.01215 Cytosol C14H20N6O5S S-Adenosylhomocysteine 384.12158 Adenosine triphosphate Autoinducer-2 ABC transporter - periplasmic binding protein B Hydrogen Ion 1.0 Phosphoribosyl-ATP C00008 KEGG Compound CHEBI:15414 ChEBI ADENINE BioCyc C00001 KEGG Compound CHEBI:18361 ChEBI phospho-AI-2 isomerase 673 PubChem-compound Inner Membrane 3-hydroxy-2,4-pentadione 5-phosphate thiolase C00002 KEGG Compound ReactionCatalysis3039 ACTIVATION 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase AI-2 transport protein TqsA Autoinducer-2 ABC transporter - periplasmic binding protein B SMILES NC1=C2NC=NC2=NC=N1 AI-2 ABC transporter - ATP binding subunit A autoinducer-2 kinase 1.0 57-04-5 CAS ReactionCatalysis3038 ACTIVATION C00019 KEGG Compound ReactionCatalysis3040 ACTIVATION ReactionCoupledTransportCatalysis158 ACTIVATION ReactionCatalysis3041 ACTIVATION 1.0 S-ADENOSYLMETHIONINE BioCyc C00010 KEGG Compound Extracellular Space C00013 KEGG Compound O7P2 Pyrophosphate 173.91193 S-ribosylhomocysteine lyase 5957 PubChem-compound GO:0005620 GENE ONTOLOGY ReactionCatalysis3042 ACTIVATION SMILES NC(CCS)C(O)=O CHEBI:16708 ChEBI 562 TAXONOMY SMILES [H][C@@](O)(CO)C(=O)C(C)=O (4S)-4-hydroxy-2,3-pentanedione 5-phosphate H Hydrogen Ion 1.007825 3-hydroxy-2,4-pentanedione 5-phosphate 388301 ChemSpider S-Adenosylhomocysteine S-ribosyl-L-homocysteine autoinducer 2 (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one autoinducer-2 ABC transporter (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran C00021 KEGG Compound 56-65-5 CAS C00147 KEGG Compound C00024 KEGG Compound P45578 UniProt Adenosine diphosphate Dimethylglycine GO:0005615 GENE ONTOLOGY Autoinducer 2 import system permease protein lsrC C10H15N5O10P2 Adenosine diphosphate 427.02942 1.0 1.0 1118-68-9 CAS ReactionCoupledTransport124 false (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + Phosphoribosyl-ATP + Water → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + Adenosine diphosphate + Hydrogen Ion + Pyrophosphate LEFT_TO_RIGHT 73-24-5 CAS C9H14NO6S S-ribosyl-L-homocysteine 264.05417 1.0 C4H9NO2 Dimethylglycine 103.06333 1.0 HMDB00092 HMDB (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran HMDB01185 HMDB CHEBI:1146900 ChEBI Water 653 ChemSpider 1.0 C00719 KEGG Compound C5H8O4 4,5-Dihydroxy-2,3-pentanedione 132.04225 P77257 UniProt SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS P0AF12 UniProt CO-A BioCyc 72-89-9 CAS 648 ChemSpider CHEBI:17750 ChEBI SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 HMDB00538 HMDB ReactionCatalysis5893 ACTIVATION SMILES CN(C)CC(O)=O P76142 UniProt Water P0AFS1 UniProt P76143 UniProt CHEBI:15422 ChEBI P0AFS5 UniProt 6557 ChemSpider 668 PubChem-compound CHEBI:17724 ChEBI Autoinducer 2 import system permease protein lsrC SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS SubPathwayInteraction1187 SubPathwayReaction SubPathway1187Reaction C01026 KEGG Compound 1.0 SMILES C[N+](C)(C)CC([O-])=O 1.0 (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran C10H16N5O13P3 Adenosine triphosphate 506.99576 1.0 DIHYDROXY-ACETONE-PHOSPHATE BioCyc CHEBI:18263 ChEBI S-ribosylhomocysteine lyase CHEBI:16761 ChEBI SMILES OCC(=O)COP(O)(O)=O 2.0 962 PubChem-compound DIMETHYL-GLYCINE BioCyc 31983 ChemSpider 10.0 5800 ChemSpider 392413 ChemSpider HMDB02111 HMDB C00080 KEGG Compound 1.0 BETAINE BioCyc Periplasmic Space 1.0 4.1.2.- false 4.1.2.- 3-hydroxy-2,4-pentanedione 5-phosphate + Coenzyme A → Acetyl-CoA + Dihydroxyacetone phosphate LEFT_TO_RIGHT C4H9NO2S Homocysteine 135.0354 CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] HMDB00742 HMDB CHEBI:16108 ChEBI 58-64-0 CAS Reaction3072 false (4S)-4-hydroxy-2,3-pentanedione 5-phosphate → 3-hydroxy-2,4-pentanedione 5-phosphate LEFT_TO_RIGHT 2.7.1.- false 2.7.1.- (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + Adenosine triphosphate → (4S)-4-hydroxy-2,3-pentanedione 5-phosphate + Adenosine diphosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Reaction3070 true (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + Water LEFT_TO_RIGHT Reaction5929 false S-ribosyl-L-homocysteine → 4,5-Dihydroxy-2,3-pentanedione + Homocysteine LEFT_TO_RIGHT S-Adenosylmethionine HOMO-CYS BioCyc Reaction3069 true autoinducer 2 → (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one LEFT_TO_RIGHT 4.4.1.21 false 4.4.1.21 S-ribosyl-L-homocysteine → Homocysteine + autoinducer 2 LEFT_TO_RIGHT 3.2.2.9 false 3.2.2.9 S-Adenosylhomocysteine + Water → S-ribosyl-L-homocysteine + Adenine LEFT_TO_RIGHT 1.0 Reaction3066 false Dimethylglycine + S-Adenosylmethionine → Betaine + Hydrogen Ion + S-Adenosylhomocysteine LEFT_TO_RIGHT 1.0 Autoinducer 2 import system permease protein lsrD 1.0 1.0 SMILES CC(=O)C(=O)C(O)CO 1.0 SMILES [N+]C(CCSCC1OC(O)C(O)C1O)C([O-])=O TransportCatalysis322 ACTIVATION TransportCatalysis321 ACTIVATION HMDB00034 HMDB SMILES CC(=O)C(O)C(=O)COP([O-])([O-])=O SMILES CC(=O)C(=O)C(O)COP([O-])([O-])=O SMILES CC1(O)OCC(O)C1(O)O SMILES CC1(O)OCC(O)C1=O HMDB03665 HMDB 644102 PubChem-compound 444493 PubChem-compound SMILES NC1=[N+](C=NC2=C1N=CN2C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O)C1OC(COP(O)(O)=O)C(O)C1O Pyrophosphate SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12)C(O)=O 757 ChemSpider (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran 25246222 PubChem-compound Homocysteine 1.0 ACETYL-COA BioCyc H2O Water 18.010565 1.0 190 PubChem-compound 4,5-Dihydroxy-2,3-pentanedione CHEBI:425228 ChEBI P77432 UniProt 29908-03-0 CAS CHEBI:16680 ChEBI CHEBI:15351 ChEBI 1.0 HMDB00043 HMDB 24762165 PubChem-compound 984 ChemSpider 185 ChemSpider Adenosine diphosphate 85-61-0 CAS B1XEA2 UniProt lsrR tqsA tqsA mtn luxS lsrK lsrG lsrF luxS lsrC lsrD lsrA (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran S- Adenosylhomocysteine Water Adenine S-ribosyl-L- homocysteine Homocysteine autoinducer 2 (2R,4S)-2- methyl-2,4- dihydroxydihydrofuran- 3-one Water (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran Adenosine triphosphate Adenosine diphosphate Hydrogen Ion (4S)-4- hydroxy-2,3- pentanedione 5-phosphate 3-hydroxy- 2,4- pentanedione 5-phosphate Coenzyme A Acetyl-CoA Dihydroxyacetone phosphate S- Adenosylmethionine Dimethylglycine Hydrogen Ion Betaine S-ribosyl-L- homocysteine 4,5- Dihydroxy- 2,3- pentanedione Homocysteine (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran Phosphoribosyl- ATP Water Adenosine diphosphate Hydrogen Ion Pyrophosphate (2R,4S)-2- methyl- 2,3,3,4- tetrahydroxytetrahydrofuran 3-hydroxy- 2,4- pentanedione 5-phosphate 3-hydroxy- 2,4- pentanedione 5-phosphate 3-hydroxy- 2,4- pentanedione 5-phosphate S-adenosyl-L- methionine biosynthesis lsrB