Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on PathBank.
Loading Pathway...
6022 PubChem-compound C00556 KEGG Compound 2.0 Phosphocarrier protein HPr C23H38N7O17P3S Acetyl-CoA 809.1258 Anaerobic glycerol-3-phosphate dehydrogenase subunit B 937 ChemSpider 439162 PubChem-compound ReactionCoupledTransportCatalysis172 ACTIVATION 1.0 HMDB00131 HMDB 46173312 PubChem-compound HMDB01341 HMDB Glucose-specific phosphotransferase enzyme IIA component 439278 PubChem-compound 2.0 439153 PubChem-compound 1.0 SMILES [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(C)C(=O)C2=CC=CC=C2C1=O)=C(\C)CCC=C(C)C 1.0 58238 ChemSpider CHEBI:16389 ChEBI HMDB01112 HMDB C6H14O12P2 Fructose 1,6-bisphosphate 339.99606 CHEBI:16027 ChEBI NAD Pyruvate kinase I ATP BioCyc HMDB00263 HMDB HMDB01473 HMDB PTS system glucose-specific EIICB component 1.2.4.1 false 1.2.4.1 Coenzyme A + NAD + Pyruvic acid → Acetyl-CoA + Carbon dioxide + NADH LEFT_TO_RIGHT Glycerophosphoryl diester phosphodiesterase 45479636 PubChem-compound P0AA04 UniProt 1.0 Glyceraldehyde-3-phosphate dehydrogenase A HMDB01206 HMDB Anaerobic glycerol-3-phosphate dehydrogenase subunit C Fructose-1,6-bisphosphatase class 1 6-phosphofructokinase II 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Fructose-bisphosphate aldolase class 1 5742 ChemSpider 6-phosphofructokinase I Fructose 1,6-bisphosphate 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HMDB59597 HMDB P0AD61 UniProt 5858 ChemSpider HMDB00243 HMDB HMDB00124 HMDB C6H13O9P Beta-D-Glucose 6-phosphate 260.02972 HMDB00126 HMDB P0A9B2 UniProt 709 ChemSpider C00221 KEGG Compound Acetyl-CoA 704 ChemSpider Fructose-1,6-bisphosphatase class 2 1010 ChemSpider Anaerobic glycerol-3-phosphate dehydrogenase subunit A 2.7.1.30 false 2.7.1.30 Adenosine triphosphate + Glycerol → Adenosine diphosphate + Glycerol 3-phosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Glycerol 1.1.1.94 false 1.1.1.94 Glycerol 3-phosphate + Ubiquinone-1 → Dihydroxyacetone phosphate + Ubiquinol-1 LEFT_TO_RIGHT Glycerol kinase 1.1.5.3 false 1.1.5.3 Glycerol 3-phosphate + menaquinone-8 → Dihydroxyacetone phosphate + Menaquinol 8 LEFT_TO_RIGHT 488-69-7 CAS 4.0 Reaction3447 false glycerophosphoserine + Water → Benzyl alcohol + Glycerol 3-phosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(O)C2=CC=CC=C2C(O)=C1C)=C(\C)CCC=C(C)C C3H7O6P D-Glyceraldehyde 3-phosphate 169.99803 138-08-9 CAS BiologicalState109 2.0 1.0 HMDB01423 HMDB C00116 KEGG Compound SubPathwayInteraction1404 SubPathwayReaction SubPathway1404Reaction Hydrogen Ion C3H8O10P2 Glyceric acid 1,3-biphosphate 265.95926 Glycerol-3-phosphate dehydrogenase [NAD(P)+] C00111 KEGG Compound Uncharacterized protein yggF Enolase Cytosol C00236 KEGG Compound Glycerol uptake facilitator protein C00597 KEGG Compound glucose PTS permease C00354 KEGG Compound Adenosine triphosphate Glucose-6-phosphate isomerase P10908 UniProt C00009 KEGG Compound 4307 ChemSpider 1.0 C00008 KEGG Compound SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O 1.0 C00001 KEGG Compound 3-Phosphoglyceric acid CHEBI:18367 ChEBI C00004 KEGG Compound 1032 ChemSpider C00003 KEGG Compound C00002 KEGG Compound 1031 ChemSpider Phosphocarrier protein HPr HMDB01429 HMDB Menaquinol 8 C51H74O2 Menaquinol 8 718.5689 2.0 388411 ChemSpider 388538 ChemSpider C21H28N7O14P2 NAD 664.11694 447920 PubChem-compound C00011 KEGG Compound C00010 KEGG Compound FRUCTOSE-6P BioCyc 2.7.1.69 false 2.7.1.69 Beta-D-Glucose + HPr - phosphorylated → Beta-D-Glucose 6-phosphate + HPr LEFT_TO_RIGHT Glycerol-3-phosphate transporter 562 TAXONOMY CHEBI:17138 ChEBI H Hydrogen Ion 1.007825 D-Glyceraldehyde 3-phosphate 388308 ChemSpider C00022 KEGG Compound Unknown 56-65-5 CAS Glyceric acid 1,3-biphosphate 53-84-9 CAS C00020 KEGG Compound Pyruvate kinase II Fructose-bisphosphate aldolase class 2 1.0 Unknown 62713 ChemSpider C00024 KEGG Compound P0A796 UniProt Phosphoglycerate kinase P0A799 UniProt 2.0 Phosphatase ybhA P21829 UniProt 1.0 SMILES [NH3+]C(COP([O-])(=O)OCC(O)CO)C([O-])=O Phosphoenolpyruvate synthase C00399 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Unknown Benzyl alcohol Water AMP BioCyc 492-61-5 CAS PTS system glucose-specific EIICB component 753 PubChem-compound GLYCEROL BioCyc Glycerophosphoryl diester phosphodiesterase_ 648 ChemSpider SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O P13033 UniProt PHOSPHO-ENOL-PYRUVATE BioCyc P0A858 UniProt HMDB00538 HMDB 1.0 24.0 SMILES OC(=O)C(=C)OP(O)(O)=O 64689 PubChem-compound C3H7O7P 3-Phosphoglyceric acid 185.99294 668 PubChem-compound 7732-18-5 CAS 1.0 P0A991 UniProt SMILES COC1=C(O)C(C)=C(CC=C(C)C)C(O)=C1OC 591-59-3 CAS 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 triosephosphate isomerase 1.0 Triosephosphate isomerase P0A6S7 UniProt P06999 UniProt P0AER0 UniProt Transport420 false Phosphate (←), Glycerol 3-phosphate (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT C10H16N5O13P3 Adenosine triphosphate 506.99576 DPG BioCyc DIHYDROXY-ACETONE-PHOSPHATE BioCyc 4.0 Anaerobic glycerol-3-phosphate dehydrogenase subunit B 1.0 445557 PubChem-compound P0A6T1 UniProt P0A993 UniProt 2-Phospho-D-glyceric acid SMILES CC(=O)C(O)=O 663 ChemSpider P0A996 UniProt C3H7O7P 2-Phospho-D-glyceric acid 185.99294 C00074 KEGG Compound CHEBI:17050 ChEBI SMILES OCC(=O)COP(O)(O)=O HMDB01967 HMDB HMDB00516 HMDB 4.0 Transport421 false Glycerol (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 962 PubChem-compound Beta-D-Glucose 1.0 724 PubChem-compound 5800 ChemSpider CO2 Carbon dioxide 43.98983 Phosphate Ubiquinone-1 733 ChemSpider C00080 KEGG Compound 4.0 Periplasmic Space C00085 KEGG Compound Pyruvate kinase I C01172 KEGG Compound 729 PubChem-compound Glycerol 3-phosphate 14265-44-2 CAS CHEBI:44897 ChEBI PYRUVATE BioCyc 58-64-0 CAS Glyceraldehyde-3-phosphate dehydrogenase A Fructose-1,6-bisphosphatase class 1 Anaerobic glycerol-3-phosphate dehydrogenase subunit C glycerol metabolism V (glycerophosphoserine) G3P BioCyc GLYCEROL-3P BioCyc Fructose-bisphosphate aldolase class 1 ReactionCatalysis2902 ACTIVATION C00093 KEGG Compound 2.0 1.0 444493 PubChem-compound 6083 PubChem-compound 2-PG BioCyc Glucose-specific phosphotransferase enzyme IIA component PW000918 PathWhiz ACETYL-COA BioCyc Anaerobic glycerol-3-phosphate dehydrogenase subunit A 60.0 C7H8O Benzyl alcohol 108.05752 H2O Water 18.010565 SMILES OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O Fructose-1,6-bisphosphatase class 2 4.0 393165 ChemSpider NADH BioCyc NAD BioCyc SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O 1.0 1.0 P37689 UniProt Carbon dioxide Glycerol-3-phosphate dehydrogenase [NAD(P)+] 1.0 Glycerol uptake facilitator protein 100-51-6 CAS SMILES OCC(O)CO 2.0 Uncharacterized protein yggF Enolase 980 ChemSpider CHEBI:15903 ChEBI P0A6P9 UniProt 820-11-1 CAS SMILES OC[C@@H](O)COP(O)(O)=O TransportCatalysis363 ACTIVATION glycerol-3-phosphate dehydrogenase (anaerobic) 244 PubChem-compound P08194 UniProt 2.0 SMILES OCC1=CC=CC=C1 NADH phosphoenolpyruvate synthetase enolase SMILES O 4.0 pyruvate kinase 56-81-5 CAS C10H14N5O7P Adenosine monophosphate 347.06308 C6H12O6 Beta-D-Glucose 180.06339 Glucose-6-phosphate isomerase HMDB00807 HMDB P62707 UniProt glycerophosphoserine C6H13O9P Beta-D-glucose 6-phosphate 260.02972 1005 PubChem-compound 34-DIMETHYLBENZYL-ALCOHOL BioCyc 643-13-0 CAS 1.0 1981-49-3 CAS Dihydroxyacetone phosphate glycerol channel GlpF 1.0 6816 PubChem-compound glycerophosphoryl diester phosphodiesterase, periplasmic C3H7O6P Dihydroxyacetone phosphate 169.99803 glycerol kinase Pyruvic acid CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 4.0 ReactionCatalysis2542 ACTIVATION TransportCatalysis364 ACTIVATION 1.0 C6H13NO8P glycerophosphoserine 258.03842 1.0 1038 PubChem-compound Pyruvate kinase II Fructose-bisphosphate aldolase class 2 GO:0005829 GENE ONTOLOGY ReactionCatalysis3405 ACTIVATION ReactionCatalysis3409 ACTIVATION ReactionCatalysis3406 ACTIVATION Adenosine monophosphate 274 ChemSpider CHEBI:16905 ChEBI HMDB00902 HMDB CHEBI:16908 ChEBI 1.0 O4P Phosphate 94.95342 C14H18O4 Ubiquinone-1 250.12051 Ubiquinol-1 GO:0070258 GENE ONTOLOGY Glycerol ReactionCatalysis3416 ACTIVATION ReactionCatalysis3417 ACTIVATION CHEBI:15946 ChEBI Phosphoglycerate kinase 5376507 PubChem-compound 1.0 683 PubChem-compound 58-68-4 CAS SMILES [O-]P([O-])([O-])=O CHEBI:61931 ChEBI C6H13O9P Fructose 6-phosphate 260.02972 124-38-9 CAS PW000779 PathWhiz P0A6F3 UniProt CHEBI:17835 ChEBI 5.3.1.1 false 5.3.1.1 D-Glyceraldehyde 3-phosphate ↔ Dihydroxyacetone phosphate REVERSIBLE SMILES COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O P69783 UniProt Inner Membrane ReactionCatalysis2622 ACTIVATION ReactionCatalysis2621 ACTIVATION Glycerol P69786 UniProt ReactionCatalysis2624 ACTIVATION C3H9O6P Glycerol 3-phosphate 172.01367 ReactionCatalysis2623 ACTIVATION ReactionCatalysis2626 ACTIVATION ReactionCatalysis2625 ACTIVATION ReactionCatalysis2628 ACTIVATION ReactionCatalysis2627 ACTIVATION 57-04-5 CAS CHEBI:44027 ChEBI Glycerol 3-phosphate C3H8O3 Glycerol 92.04734 69507 PubChem-compound Beta-D-glucose 6-phosphate SMP00802 SMPDB ReactionCatalysis2629 ACTIVATION SMILES O=C=O Glycerophosphoryl diester phosphodiesterase ReactionCatalysis2633 ACTIVATION ReactionCatalysis2632 ACTIVATION ReactionCatalysis2634 ACTIVATION Fructose 6-phosphate C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound Triosephosphate isomerase CHEBI:15978 ChEBI GO:0005620 GENE ONTOLOGY ReactionCatalysis2631 ACTIVATION Beta-D-Glucose 6-phosphate 1.0 ReactionCatalysis2630 ACTIVATION SMP00935 SMPDB 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 6-phosphofructokinase II 6-phosphofructokinase I phosphoglycerate mutase P09394 UniProt 6-phosphofructokinase-1 Adenosine diphosphate Glyceraldehyde 3-phosphate dehydrogenase C3H5O6P Phosphoenolpyruvic acid 167.98238 fructose bisphosphate aldolase fructose-1,6-bisphosphatase C10H15N5O10P2 Adenosine diphosphate 427.02942 phosphoglucose isomerase HMDB03391 HMDB fructose 1,6-bisphosphatase 2 Fructose-1,6-bisphosphatase 1 Phosphoenolpyruvic acid 1.0 menaquinone-8 CHEBI:17987 ChEBI CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 10.0 Glycerol kinase 5682 ChemSpider CHEBI:1146900 ChEBI Phosphate CO-A BioCyc 72-89-9 CAS HMDB03498 HMDB Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 SMILES OC(COP(O)(O)=O)C(=O)OP(O)(O)=O 1.0 1.0 439427 PubChem-compound CHEBI:15422 ChEBI 6557 ChemSpider SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 388299 ChemSpider HMDB02012 HMDB P23538 UniProt 2.7.9.2 false 2.7.9.2 Adenosine monophosphate + 2 Hydrogen Ion + Phosphate + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid + Water LEFT_TO_RIGHT P21599 UniProt 127-17-3 CAS 1.0 CHEBI:17719 ChEBI 2.7.1.40 false 2.7.1.40 Adenosine diphosphate + Hydrogen Ion + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid LEFT_TO_RIGHT HMDB01058 HMDB FRUCTOSE-16-DIPHOSPHATE BioCyc C51H72O2 menaquinone-8 716.5532 Reaction2638 false 3-Phosphoglyceric acid → 2-Phospho-D-glyceric acid LEFT_TO_RIGHT 1.0 4.2.1.11 false 4.2.1.11 2-Phospho-D-glyceric acid → Phosphoenolpyruvic acid + Water LEFT_TO_RIGHT CHEBI:16526 ChEBI HMDB03119 HMDB SMILES O[C@H]1[C@H](O)[C@](O)(COP(O)(O)=O)O[C@@H]1COP(O)(O)=O Glycerol-3-phosphate transporter TCA cycle SubPathway 1.0 1.0 CHEBI:16761 ChEBI Glycerol 3-phosphate 1.0 2.7.2.3 false 2.7.2.3 Adenosine diphosphate + Glyceric acid 1,3-biphosphate → 3-Phosphoglyceric acid + Adenosine triphosphate LEFT_TO_RIGHT Reaction2637 false 3-Phosphoglyceric acid → 2-Phospho-D-glyceric acid LEFT_TO_RIGHT 4.1.2.13 false 4.1.2.13 Fructose 1,6-bisphosphate ↔ D-Glyceraldehyde 3-phosphate + Dihydroxyacetone phosphate REVERSIBLE 1.2.1.12 false 1.2.1.12 D-Glyceraldehyde 3-phosphate + NAD + Phosphate → Glyceric acid 1,3-biphosphate + Hydrogen Ion + NADH LEFT_TO_RIGHT 3.1.3.11 false 3.1.3.11 Fructose 6-phosphate + Phosphate → Fructose 1,6-bisphosphate + Water LEFT_TO_RIGHT Reaction2633 false Adenosine triphosphate + Fructose 6-phosphate → Adenosine diphosphate + Fructose 1,6-bisphosphate + Hydrogen Ion LEFT_TO_RIGHT 5.3.1.9 false 5.3.1.9 Beta-D-glucose 6-phosphate → Fructose 6-phosphate LEFT_TO_RIGHT P0A9C0 UniProt Unknown Unknown 392413 ChemSpider SMILES OC(COP(O)(O)=O)C(O)=O glycerol-3-phosphate dehydrogenase (aerobic) C14H20O4 Ubiquinol-1 252.13615 Phosphatase ybhA P0A9C9 UniProt C00631 KEGG Compound 1.0 5893 PubChem-compound HMDB02111 HMDB 1.0 Pyruvate dehydrogenase complex CHEBI:32816 ChEBI CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] Phosphoenolpyruvate synthase CHEBI:16108 ChEBI 17989-41-2 CAS HMDB01270 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 60.0 Unknown SMILES OC[C@@H](OP(O)(O)=O)C(O)=O Phosphate 1.0 280 PubChem-compound 2.0 1.0 HMDB01487 HMDB 4462 PubChem-compound CHEBI:17522 ChEBI Glycerophosphoryl diester phosphodiesterase_ 2.0 SMILES OC(COP(O)(O)=O)C=O 10.0 P21437 UniProt 727-81-1 CAS 2.0 GAP BioCyc HMDB00045 HMDB 1060 PubChem-compound 1061 PubChem-compound C00661 KEGG Compound CHEBI:15351 ChEBI 13860335 ChemSpider 85-61-0 CAS P0AB71 UniProt CHEBI:61684 ChEBI Glycerol-3- phosphate transporter Glycerol uptake facilitator protein Glucose-6- phosphate isomerase Fructose-1,6- bisphosphatase class 2 Fructose-1,6- bisphosphatase class 1 Uncharacterized protein yggF Phosphatase ybhA 6- phosphofructokinase I 6- phosphofructokinase II Glyceraldehyde- 3-phosphate dehydrogenase A Phosphoglycerate kinase 2,3- bisphosphoglycerate- independent phosphoglycerate mutase 2,3- bisphosphoglycerate- dependent phosphoglycerate mutase Enolase Phosphoenolpyruvate synthase Pyruvate kinase I Pyruvate kinase II Unknown Unknown Unknown Unknown Fructose- bisphosphate aldolase class 1 Fructose- bisphosphate aldolase class 2 Triosephosphate isomerase Glycerol kinase Glycerol-3- phosphate dehydrogenase [NAD(P)+] Anaerobic glycerol-3- phosphate dehydrogenase subunit A Anaerobic glycerol-3- phosphate dehydrogenase subunit B Anaerobic glycerol-3- phosphate dehydrogenase subunit C Phosphocarrier protein HPr Phosphocarrier protein HPr PTS system glucose- specific EIICB component Glucose- specific phosphotransferase enzyme IIA component P i P i Glycerol 3-phosphate Glycerol 3-phosphate Glycerol Glycerol Beta-D-glucose 6-phosphate Fructose 6-phosphate P i Fructose 1,6- bisphosphate H 2 O ATP Fructose 1,6- bisphosphate ADP H + D- Glyceraldehyde 3-phosphate NAD P i Glyceric acid 1,3-biphosphate NADH H + ADP ATP 3- Phosphoglyceric acid 2-Phospho-D- glyceric acid 2-Phospho-D- glyceric acid Phosphoenolpyruvic acid H 2 O AMP P i H + ATP H 2 O Pyruvic acid ADP H + ATP Pyruvic acid CoA NAD Acetyl-CoA CO 2 NADH D- Glyceraldehyde 3-phosphate Dihydroxyacetone phosphate D- Glyceraldehyde 3-phosphate Glycerol ATP H + ADP Glycerol 3-phosphate glycerophosphoserine H 2 O H + Benzyl alcohol Ubiquinone-1 Dihydroxyacetone phosphate Ubiquinol-1 menaquinone-8 Menaquinol 8 Dihydroxyacetone phosphate Beta-D-Glucose 6-phosphate Beta-D-Glucose 6-phosphate Magnesium Glycerophosphoryl diester phosphodiesterase TCA cycle Glycerophosphoryl diester phosphodiesterase_ Calcium Magnesium
6022 PubChem-compound C00556 KEGG Compound 2.0 Phosphocarrier protein HPr C23H38N7O17P3S Acetyl-CoA 809.1258 Anaerobic glycerol-3-phosphate dehydrogenase subunit B 937 ChemSpider 439162 PubChem-compound ReactionCoupledTransportCatalysis172 ACTIVATION 1.0 HMDB00131 HMDB 46173312 PubChem-compound HMDB01341 HMDB Glucose-specific phosphotransferase enzyme IIA component 439278 PubChem-compound 2.0 439153 PubChem-compound 1.0 SMILES [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(C)C(=O)C2=CC=CC=C2C1=O)=C(\C)CCC=C(C)C 1.0 58238 ChemSpider CHEBI:16389 ChEBI HMDB01112 HMDB C6H14O12P2 Fructose 1,6-bisphosphate 339.99606 CHEBI:16027 ChEBI NAD Pyruvate kinase I ATP BioCyc HMDB00263 HMDB HMDB01473 HMDB PTS system glucose-specific EIICB component 1.2.4.1 false 1.2.4.1 Coenzyme A + NAD + Pyruvic acid → Acetyl-CoA + Carbon dioxide + NADH LEFT_TO_RIGHT Glycerophosphoryl diester phosphodiesterase 45479636 PubChem-compound P0AA04 UniProt 1.0 Glyceraldehyde-3-phosphate dehydrogenase A HMDB01206 HMDB Anaerobic glycerol-3-phosphate dehydrogenase subunit C Fructose-1,6-bisphosphatase class 1 6-phosphofructokinase II 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Fructose-bisphosphate aldolase class 1 5742 ChemSpider 6-phosphofructokinase I Fructose 1,6-bisphosphate 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HMDB59597 HMDB P0AD61 UniProt 5858 ChemSpider HMDB00243 HMDB HMDB00124 HMDB C6H13O9P Beta-D-Glucose 6-phosphate 260.02972 HMDB00126 HMDB P0A9B2 UniProt 709 ChemSpider C00221 KEGG Compound Acetyl-CoA 704 ChemSpider Fructose-1,6-bisphosphatase class 2 1010 ChemSpider Anaerobic glycerol-3-phosphate dehydrogenase subunit A 2.7.1.30 false 2.7.1.30 Adenosine triphosphate + Glycerol → Adenosine diphosphate + Glycerol 3-phosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Glycerol 1.1.1.94 false 1.1.1.94 Glycerol 3-phosphate + Ubiquinone-1 → Dihydroxyacetone phosphate + Ubiquinol-1 LEFT_TO_RIGHT Glycerol kinase 1.1.5.3 false 1.1.5.3 Glycerol 3-phosphate + menaquinone-8 → Dihydroxyacetone phosphate + Menaquinol 8 LEFT_TO_RIGHT 488-69-7 CAS 4.0 Reaction3447 false glycerophosphoserine + Water → Benzyl alcohol + Glycerol 3-phosphate + Hydrogen Ion LEFT_TO_RIGHT SMILES [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC1=C(O)C2=CC=CC=C2C(O)=C1C)=C(\C)CCC=C(C)C C3H7O6P D-Glyceraldehyde 3-phosphate 169.99803 138-08-9 CAS BiologicalState109 Escherichia coli, Inner Membrane 2.0 1.0 HMDB01423 HMDB C00116 KEGG Compound SubPathwayInteraction1404 SubPathwayReaction SubPathway1404Reaction Hydrogen Ion C3H8O10P2 Glyceric acid 1,3-biphosphate 265.95926 Glycerol-3-phosphate dehydrogenase [NAD(P)+] C00111 KEGG Compound Uncharacterized protein yggF Enolase Cytosol C00236 KEGG Compound Glycerol uptake facilitator protein C00597 KEGG Compound glucose PTS permease C00354 KEGG Compound Adenosine triphosphate Glucose-6-phosphate isomerase P10908 UniProt C00009 KEGG Compound 4307 ChemSpider 1.0 C00008 KEGG Compound SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O 1.0 C00001 KEGG Compound 3-Phosphoglyceric acid CHEBI:18367 ChEBI C00004 KEGG Compound 1032 ChemSpider C00003 KEGG Compound C00002 KEGG Compound 1031 ChemSpider Phosphocarrier protein HPr HMDB01429 HMDB Menaquinol 8 C51H74O2 Menaquinol 8 718.5689 2.0 388411 ChemSpider 388538 ChemSpider C21H28N7O14P2 NAD 664.11694 447920 PubChem-compound C00011 KEGG Compound C00010 KEGG Compound FRUCTOSE-6P BioCyc 2.7.1.69 false 2.7.1.69 Beta-D-Glucose + HPr - phosphorylated → Beta-D-Glucose 6-phosphate + HPr LEFT_TO_RIGHT Glycerol-3-phosphate transporter 562 TAXONOMY CHEBI:17138 ChEBI H Hydrogen Ion 1.007825 D-Glyceraldehyde 3-phosphate 388308 ChemSpider C00022 KEGG Compound Unknown 56-65-5 CAS Glyceric acid 1,3-biphosphate 53-84-9 CAS C00020 KEGG Compound Pyruvate kinase II Fructose-bisphosphate aldolase class 2 1.0 Unknown 62713 ChemSpider C00024 KEGG Compound P0A796 UniProt Phosphoglycerate kinase P0A799 UniProt 2.0 Phosphatase ybhA P21829 UniProt 1.0 SMILES [NH3+]C(COP([O-])(=O)OCC(O)CO)C([O-])=O Phosphoenolpyruvate synthase C00399 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Unknown Benzyl alcohol Water AMP BioCyc 492-61-5 CAS PTS system glucose-specific EIICB component 753 PubChem-compound GLYCEROL BioCyc Glycerophosphoryl diester phosphodiesterase_ 648 ChemSpider SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O P13033 UniProt PHOSPHO-ENOL-PYRUVATE BioCyc P0A858 UniProt HMDB00538 HMDB 1.0 24.0 SMILES OC(=O)C(=C)OP(O)(O)=O 64689 PubChem-compound C3H7O7P 3-Phosphoglyceric acid 185.99294 668 PubChem-compound 7732-18-5 CAS 1.0 P0A991 UniProt SMILES COC1=C(O)C(C)=C(CC=C(C)C)C(O)=C1OC 591-59-3 CAS 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 SMILES OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O 1.0 triosephosphate isomerase 1.0 Triosephosphate isomerase P0A6S7 UniProt P06999 UniProt P0AER0 UniProt Transport420 false Phosphate (←), Glycerol 3-phosphate (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT C10H16N5O13P3 Adenosine triphosphate 506.99576 DPG BioCyc DIHYDROXY-ACETONE-PHOSPHATE BioCyc 4.0 Anaerobic glycerol-3-phosphate dehydrogenase subunit B 1.0 445557 PubChem-compound P0A6T1 UniProt P0A993 UniProt 2-Phospho-D-glyceric acid SMILES CC(=O)C(O)=O 663 ChemSpider P0A996 UniProt C3H7O7P 2-Phospho-D-glyceric acid 185.99294 C00074 KEGG Compound CHEBI:17050 ChEBI SMILES OCC(=O)COP(O)(O)=O HMDB01967 HMDB HMDB00516 HMDB 4.0 Transport421 false Glycerol (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 962 PubChem-compound Beta-D-Glucose 1.0 724 PubChem-compound 5800 ChemSpider CO2 Carbon dioxide 43.98983 Phosphate Ubiquinone-1 733 ChemSpider C00080 KEGG Compound 4.0 Periplasmic Space C00085 KEGG Compound Pyruvate kinase I C01172 KEGG Compound 729 PubChem-compound Glycerol 3-phosphate 14265-44-2 CAS CHEBI:44897 ChEBI PYRUVATE BioCyc 58-64-0 CAS Glyceraldehyde-3-phosphate dehydrogenase A Fructose-1,6-bisphosphatase class 1 Anaerobic glycerol-3-phosphate dehydrogenase subunit C glycerol metabolism V (glycerophosphoserine) G3P BioCyc GLYCEROL-3P BioCyc Fructose-bisphosphate aldolase class 1 ReactionCatalysis2902 ACTIVATION C00093 KEGG Compound 2.0 1.0 444493 PubChem-compound 6083 PubChem-compound 2-PG BioCyc Glucose-specific phosphotransferase enzyme IIA component PW000918 PathWhiz ACETYL-COA BioCyc Anaerobic glycerol-3-phosphate dehydrogenase subunit A 60.0 C7H8O Benzyl alcohol 108.05752 H2O Water 18.010565 SMILES OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O Fructose-1,6-bisphosphatase class 2 4.0 393165 ChemSpider NADH BioCyc NAD BioCyc SMILES O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H]1O 1.0 1.0 P37689 UniProt Carbon dioxide Glycerol-3-phosphate dehydrogenase [NAD(P)+] 1.0 Glycerol uptake facilitator protein 100-51-6 CAS SMILES OCC(O)CO 2.0 Uncharacterized protein yggF Enolase 980 ChemSpider CHEBI:15903 ChEBI P0A6P9 UniProt 820-11-1 CAS SMILES OC[C@@H](O)COP(O)(O)=O TransportCatalysis363 ACTIVATION glycerol-3-phosphate dehydrogenase (anaerobic) 244 PubChem-compound P08194 UniProt 2.0 SMILES OCC1=CC=CC=C1 NADH phosphoenolpyruvate synthetase enolase SMILES O 4.0 pyruvate kinase 56-81-5 CAS C10H14N5O7P Adenosine monophosphate 347.06308 C6H12O6 Beta-D-Glucose 180.06339 Glucose-6-phosphate isomerase HMDB00807 HMDB P62707 UniProt glycerophosphoserine C6H13O9P Beta-D-glucose 6-phosphate 260.02972 1005 PubChem-compound 34-DIMETHYLBENZYL-ALCOHOL BioCyc 643-13-0 CAS 1.0 1981-49-3 CAS Dihydroxyacetone phosphate glycerol channel GlpF 1.0 6816 PubChem-compound glycerophosphoryl diester phosphodiesterase, periplasmic C3H7O6P Dihydroxyacetone phosphate 169.99803 glycerol kinase Pyruvic acid CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 4.0 ReactionCatalysis2542 ACTIVATION TransportCatalysis364 ACTIVATION 1.0 C6H13NO8P glycerophosphoserine 258.03842 1.0 1038 PubChem-compound Pyruvate kinase II Fructose-bisphosphate aldolase class 2 GO:0005829 GENE ONTOLOGY ReactionCatalysis3405 ACTIVATION ReactionCatalysis3409 ACTIVATION ReactionCatalysis3406 ACTIVATION Adenosine monophosphate 274 ChemSpider CHEBI:16905 ChEBI HMDB00902 HMDB CHEBI:16908 ChEBI 1.0 O4P Phosphate 94.95342 C14H18O4 Ubiquinone-1 250.12051 Ubiquinol-1 GO:0070258 GENE ONTOLOGY Glycerol ReactionCatalysis3416 ACTIVATION ReactionCatalysis3417 ACTIVATION TCA cycle SubPathway CHEBI:15946 ChEBI Phosphoglycerate kinase 5376507 PubChem-compound 1.0 683 PubChem-compound 58-68-4 CAS SMILES [O-]P([O-])([O-])=O CHEBI:61931 ChEBI C6H13O9P Fructose 6-phosphate 260.02972 124-38-9 CAS PW000779 PathWhiz P0A6F3 UniProt CHEBI:17835 ChEBI 5.3.1.1 false 5.3.1.1 D-Glyceraldehyde 3-phosphate ↔ Dihydroxyacetone phosphate REVERSIBLE SMILES COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O P69783 UniProt Inner Membrane ReactionCatalysis2622 ACTIVATION ReactionCatalysis2621 ACTIVATION Glycerol P69786 UniProt ReactionCatalysis2624 ACTIVATION C3H9O6P Glycerol 3-phosphate 172.01367 ReactionCatalysis2623 ACTIVATION ReactionCatalysis2626 ACTIVATION ReactionCatalysis2625 ACTIVATION ReactionCatalysis2628 ACTIVATION ReactionCatalysis2627 ACTIVATION 57-04-5 CAS CHEBI:44027 ChEBI Glycerol 3-phosphate C3H8O3 Glycerol 92.04734 69507 PubChem-compound Beta-D-glucose 6-phosphate http://identifiers.org/smpdb/SMP00802 SMPDB ReactionCatalysis2629 ACTIVATION SMILES O=C=O Glycerophosphoryl diester phosphodiesterase ReactionCatalysis2633 ACTIVATION ReactionCatalysis2632 ACTIVATION ReactionCatalysis2634 ACTIVATION Fructose 6-phosphate C21H29N7O14P2 NADH 665.12476 5957 PubChem-compound Triosephosphate isomerase CHEBI:15978 ChEBI GO:0005620 GENE ONTOLOGY ReactionCatalysis2631 ACTIVATION Beta-D-Glucose 6-phosphate 1.0 ReactionCatalysis2630 ACTIVATION http://identifiers.org/smpdb/SMP00935 SMPDB 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 6-phosphofructokinase II 6-phosphofructokinase I phosphoglycerate mutase P09394 UniProt 6-phosphofructokinase-1 Adenosine diphosphate Glyceraldehyde 3-phosphate dehydrogenase C3H5O6P Phosphoenolpyruvic acid 167.98238 fructose bisphosphate aldolase fructose-1,6-bisphosphatase C10H15N5O10P2 Adenosine diphosphate 427.02942 phosphoglucose isomerase HMDB03391 HMDB fructose 1,6-bisphosphatase 2 Fructose-1,6-bisphosphatase 1 Phosphoenolpyruvic acid 1.0 menaquinone-8 CHEBI:17987 ChEBI CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 10.0 Glycerol kinase 5682 ChemSpider CHEBI:1146900 ChEBI Phosphate CO-A BioCyc 72-89-9 CAS HMDB03498 HMDB Coenzyme A C21H36N7O16P3S Coenzyme A 767.11523 SMILES OC(COP(O)(O)=O)C(=O)OP(O)(O)=O 1.0 1.0 439427 PubChem-compound CHEBI:15422 ChEBI 6557 ChemSpider SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 388299 ChemSpider HMDB02012 HMDB P23538 UniProt 2.7.9.2 false 2.7.9.2 Adenosine monophosphate + 2 Hydrogen Ion + Phosphate + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid + Water LEFT_TO_RIGHT P21599 UniProt 127-17-3 CAS 1.0 CHEBI:17719 ChEBI 2.7.1.40 false 2.7.1.40 Adenosine diphosphate + Hydrogen Ion + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid LEFT_TO_RIGHT HMDB01058 HMDB FRUCTOSE-16-DIPHOSPHATE BioCyc C51H72O2 menaquinone-8 716.5532 Reaction2638 false 3-Phosphoglyceric acid → 2-Phospho-D-glyceric acid LEFT_TO_RIGHT 1.0 4.2.1.11 false 4.2.1.11 2-Phospho-D-glyceric acid → Phosphoenolpyruvic acid + Water LEFT_TO_RIGHT CHEBI:16526 ChEBI HMDB03119 HMDB SMILES O[C@H]1[C@H](O)[C@](O)(COP(O)(O)=O)O[C@@H]1COP(O)(O)=O Glycerol-3-phosphate transporter 1.0 1.0 CHEBI:16761 ChEBI Glycerol 3-phosphate 1.0 2.7.2.3 false 2.7.2.3 Adenosine diphosphate + Glyceric acid 1,3-biphosphate → 3-Phosphoglyceric acid + Adenosine triphosphate LEFT_TO_RIGHT Reaction2637 false 3-Phosphoglyceric acid → 2-Phospho-D-glyceric acid LEFT_TO_RIGHT 4.1.2.13 false 4.1.2.13 Fructose 1,6-bisphosphate ↔ D-Glyceraldehyde 3-phosphate + Dihydroxyacetone phosphate REVERSIBLE 1.2.1.12 false 1.2.1.12 D-Glyceraldehyde 3-phosphate + NAD + Phosphate → Glyceric acid 1,3-biphosphate + Hydrogen Ion + NADH LEFT_TO_RIGHT 3.1.3.11 false 3.1.3.11 Fructose 6-phosphate + Phosphate → Fructose 1,6-bisphosphate + Water LEFT_TO_RIGHT Reaction2633 false Adenosine triphosphate + Fructose 6-phosphate → Adenosine diphosphate + Fructose 1,6-bisphosphate + Hydrogen Ion LEFT_TO_RIGHT 5.3.1.9 false 5.3.1.9 Beta-D-glucose 6-phosphate → Fructose 6-phosphate LEFT_TO_RIGHT P0A9C0 UniProt Unknown Unknown 392413 ChemSpider SMILES OC(COP(O)(O)=O)C(O)=O glycerol-3-phosphate dehydrogenase (aerobic) C14H20O4 Ubiquinol-1 252.13615 Phosphatase ybhA P0A9C9 UniProt C00631 KEGG Compound 1.0 5893 PubChem-compound HMDB02111 HMDB 1.0 Pyruvate dehydrogenase complex CHEBI:32816 ChEBI CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] Phosphoenolpyruvate synthase CHEBI:16108 ChEBI 17989-41-2 CAS HMDB01270 HMDB SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 60.0 Unknown SMILES OC[C@@H](OP(O)(O)=O)C(O)=O Phosphate 1.0 280 PubChem-compound 2.0 1.0 HMDB01487 HMDB 4462 PubChem-compound CHEBI:17522 ChEBI Glycerophosphoryl diester phosphodiesterase_ 2.0 SMILES OC(COP(O)(O)=O)C=O 10.0 P21437 UniProt 727-81-1 CAS 2.0 GAP BioCyc HMDB00045 HMDB 1060 PubChem-compound 1061 PubChem-compound C00661 KEGG Compound CHEBI:15351 ChEBI 13860335 ChemSpider 85-61-0 CAS P0AB71 UniProt CHEBI:61684 ChEBI