Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Small Molecule Pathway Database.
Loading Pathway...
C3H7NO4S 3-Sulfinoalanine 153.00958 SMILES N[C@@H](CS)C(O)=O 1.0 C05844 KEGG Compound CL:0000000 CELL TYPE ONTOLOGY 52-90-4 CAS 300-84-5 CAS CYS BioCyc HMDB00251 HMDB Glutamate decarboxylase 1 Cysteine sulfinic acid decarboxylase 1091 ChemSpider 1.0 SMILES NCCS(O)(=O)=O SMP00021 SMPDB 1.13.11.19 false 1.13.11.19 Cysteamine + Oxygen → Hypotaurine LEFT_TO_RIGHT 107812 PubChem-compound ReactionCatalysis421 ACTIVATION ReactionCatalysis422 ACTIVATION ReactionCatalysis420 ACTIVATION CHEBI:16668 ChEBI C00606 KEGG Compound 5834 ChemSpider 1123 PubChem-compound 439270 PubChem-compound Glutamate decarboxylase 1 SMILES NC(CS(O)(=O)=O)C(O)=O Peptide Q96SZ5 UniProt Gamma-glutamyltransferase 6 5-L-Glutamyl-taurine SMILES N[C@@H](CCC(=O)NCCS(O)(=O)=O)C(O)=O 1115-65-7 CAS 1.0 13100-82-8 CAS ReactionCatalysis418 ACTIVATION Cytoplasm ReactionCatalysis419 ACTIVATION SMP00035 SMPDB Taurine and Hypotaurine Metabolism 1.0 ReactionCatalysis417 ACTIVATION Cell A (5-L-glutamyl)-peptide Peptide 2-aminoethanethiol dioxygenase HMDB00996 HMDB SMILES N[C@@H](CS(=O)=O)C(O)=O 2.0 Glutamate decarboxylase 1 3-Sulfinoalanine CHEBI:17561 ChEBI 952 ChemSpider Cysteic acid O2 Oxygen 31.98983 Carbon dioxide L-Cysteine SubPathwayOutput 274 ChemSpider Cysteine Metabolism SubPathway Glutathione Metabolism SubPathway C2H7NO2S Hypotaurine 109.01975 Bile Acid Biosynthesis SubPathway Q9Y600 UniProt 1.0 C01678 KEGG Compound PW000038 PathWhiz 107-35-7 CAS C00506 KEGG Compound CHEBI:16526 ChEBI 2-aminoethanethiol dioxygenase 5862 PubChem-compound 7782-44-7 CAS CHEBI:21260 ChEBI 1.0 C2H7NS Cysteamine 77.02992 HMDB01967 HMDB A (5-L-glutamyl)-peptide 25701 PubChem-compound 68759 PubChem-compound 9606 TAXONOMY PW000145 PathWhiz HMDB00574 HMDB C00519 KEGG Compound HMDB02757 HMDB 3-SULFINOALANINE BioCyc CHEBI:17141 ChEBI 62003 ChemSpider CPD-6641 BioCyc CO2 Carbon dioxide 43.98983 L-CYSTEATE BioCyc HMDB02991 HMDB SMILES O=O Q99259 UniProt 1.0 SMILES NCCS(O)=O BiologicalState8 1.13.11.20 false 1.13.11.20 L-Cysteine + Oxygen → 3-Sulfinoalanine LEFT_TO_RIGHT 124-38-9 CAS PW000018 PathWhiz 1.0 1.0 C00007 KEGG Compound CHEBI:15379 ChEBI Cysteine sulfinic acid decarboxylase Hypotaurine 6058 PubChem-compound C00245 KEGG Compound CHEBI:15891 ChEBI 16743745 ChemSpider 280 PubChem-compound SMILES NCCS ReactionCatalysis219 ACTIVATION 96959 ChemSpider Q16878 UniProt Oxygen Cysteine dioxygenase type 1 SubPathwayInteraction255 SubPathwayReaction SubPathway255Reaction C3H7NO2S L-Cysteine 121.01975 4.1.1.29 false 4.1.1.29 Cysteic acid → Carbon dioxide + Taurine LEFT_TO_RIGHT Reaction857 false A (5-L-glutamyl)-peptide + Taurine → 5-L-Glutamyl-taurine + Peptide LEFT_TO_RIGHT 4.1.1.29 false 4.1.1.29 3-Sulfinoalanine → Carbon dioxide + Hypotaurine LEFT_TO_RIGHT PW000004 PathWhiz Reaction855 true 3-Sulfinoalanine → Cysteic acid LEFT_TO_RIGHT C00011 KEGG Compound SMILES O=C=O Cysteine sulfinic acid decarboxylase Taurine SubPathwayInput 1.0 HMDB04195 HMDB C00097 KEGG Compound 2.0 CHEBI:16670 ChEBI 23942 ChemSpider C2H7NO3S Taurine 125.01466 Reaction853 true L-Cysteine → Carbon dioxide + Cysteamine LEFT_TO_RIGHT 60-23-1 CAS CHEBI:15857 ChEBI 2.0 SubPathwayInteraction253 SubPathwayReaction SubPathway253Reaction SubPathwayInteraction254 SubPathway254Reaction SubPathwayReaction HMDB01377 HMDB Gamma-glutamyltransferase 6 CHEBI:41721 ChEBI 977 PubChem-compound 56488-60-9 CAS Gamma-glutamyltransferase 6 CPD-3721 BioCyc HMDB00965 HMDB 5653 ChemSpider C3H7NO5S Cysteic acid 169.00449 HYPOTAURINE BioCyc C7H14N2O6S 5-L-Glutamyl-taurine 254.05725 GO:0005737 GENE ONTOLOGY Cysteine dioxygenase type 1 Q6P531 UniProt 1.0 SMP00013 SMPDB Cysteamine SMP00015 SMPDB Cysteine dioxygenase type 1 2- aminoethanethiol dioxygenase Cysteine sulfinic acid decarboxylase Glutamate decarboxylase 1 Cysteine sulfinic acid decarboxylase Glutamate decarboxylase 1 Gamma- glutamyltransferase 6 Taurine L-Cysteine O 2 3-Sulfinoalanine Cysteamine CO 2 O 2 Hypotaurine CO 2 CO 2 Cysteic acid CO 2 CO 2 5-L-Glutamyl-taurine Fe2+ Iron Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Bile Acid Biosynthesis Cysteine Metabolism Glutathione Metabolism Extracellular Space Intracellular Space
C3H7NO4S 3-Sulfinoalanine 153.00958 SMILES N[C@@H](CS)C(O)=O 1.0 C05844 KEGG Compound CL:0000000 CELL TYPE ONTOLOGY 52-90-4 CAS 300-84-5 CAS CYS BioCyc HMDB00251 HMDB Glutamate decarboxylase 1 Cysteine sulfinic acid decarboxylase 1091 ChemSpider 1.0 SMILES NCCS(O)(=O)=O http://identifiers.org/smpdb/SMP00021 SMPDB 1.13.11.19 false 1.13.11.19 Cysteamine + Oxygen → Hypotaurine LEFT_TO_RIGHT 107812 PubChem-compound ReactionCatalysis421 ACTIVATION ReactionCatalysis422 ACTIVATION ReactionCatalysis420 ACTIVATION CHEBI:16668 ChEBI C00606 KEGG Compound 5834 ChemSpider 1123 PubChem-compound 439270 PubChem-compound Glutamate decarboxylase 1 SMILES NC(CS(O)(=O)=O)C(O)=O Peptide Q96SZ5 UniProt Gamma-glutamyltransferase 6 5-L-Glutamyl-taurine SMILES N[C@@H](CCC(=O)NCCS(O)(=O)=O)C(O)=O 1115-65-7 CAS 1.0 13100-82-8 CAS ReactionCatalysis418 ACTIVATION Cytoplasm ReactionCatalysis419 ACTIVATION http://identifiers.org/smpdb/SMP00035 SMPDB Taurine and Hypotaurine Metabolism 1.0 ReactionCatalysis417 ACTIVATION Cell A (5-L-glutamyl)-peptide Peptide 2-aminoethanethiol dioxygenase HMDB00996 HMDB SMILES N[C@@H](CS(=O)=O)C(O)=O 2.0 Glutamate decarboxylase 1 3-Sulfinoalanine CHEBI:17561 ChEBI 952 ChemSpider Cysteic acid O2 Oxygen 31.98983 Carbon dioxide L-Cysteine SubPathwayOutput 274 ChemSpider Cysteine Metabolism SubPathway Glutathione Metabolism SubPathway C2H7NO2S Hypotaurine 109.01975 Bile Acid Biosynthesis SubPathway Q9Y600 UniProt 1.0 C01678 KEGG Compound PW000038 PathWhiz 107-35-7 CAS C00506 KEGG Compound CHEBI:16526 ChEBI 2-aminoethanethiol dioxygenase 5862 PubChem-compound 7782-44-7 CAS CHEBI:21260 ChEBI 1.0 C2H7NS Cysteamine 77.02992 HMDB01967 HMDB A (5-L-glutamyl)-peptide 25701 PubChem-compound 68759 PubChem-compound 9606 TAXONOMY PW000145 PathWhiz HMDB00574 HMDB C00519 KEGG Compound HMDB02757 HMDB 3-SULFINOALANINE BioCyc CHEBI:17141 ChEBI 62003 ChemSpider CPD-6641 BioCyc CO2 Carbon dioxide 43.98983 L-CYSTEATE BioCyc HMDB02991 HMDB SMILES O=O Q99259 UniProt 1.0 SMILES NCCS(O)=O BiologicalState8 Homo sapiens, Cell, Cytoplasm 1.13.11.20 false 1.13.11.20 L-Cysteine + Oxygen → 3-Sulfinoalanine LEFT_TO_RIGHT 124-38-9 CAS PW000018 PathWhiz 1.0 1.0 C00007 KEGG Compound CHEBI:15379 ChEBI Cysteine sulfinic acid decarboxylase Hypotaurine 6058 PubChem-compound C00245 KEGG Compound CHEBI:15891 ChEBI 16743745 ChemSpider 280 PubChem-compound SMILES NCCS ReactionCatalysis219 ACTIVATION 96959 ChemSpider Q16878 UniProt Oxygen Cysteine dioxygenase type 1 SubPathwayInteraction255 SubPathwayReaction SubPathway255Reaction C3H7NO2S L-Cysteine 121.01975 4.1.1.29 false 4.1.1.29 Cysteic acid → Carbon dioxide + Taurine LEFT_TO_RIGHT Reaction857 false A (5-L-glutamyl)-peptide + Taurine → 5-L-Glutamyl-taurine + Peptide LEFT_TO_RIGHT 4.1.1.29 false 4.1.1.29 3-Sulfinoalanine → Carbon dioxide + Hypotaurine LEFT_TO_RIGHT PW000004 PathWhiz Reaction855 true 3-Sulfinoalanine → Cysteic acid LEFT_TO_RIGHT C00011 KEGG Compound SMILES O=C=O Cysteine sulfinic acid decarboxylase Taurine SubPathwayInput 1.0 HMDB04195 HMDB C00097 KEGG Compound 2.0 CHEBI:16670 ChEBI 23942 ChemSpider C2H7NO3S Taurine 125.01466 Reaction853 true L-Cysteine → Carbon dioxide + Cysteamine LEFT_TO_RIGHT 60-23-1 CAS CHEBI:15857 ChEBI 2.0 SubPathwayInteraction253 SubPathwayReaction SubPathway253Reaction SubPathwayInteraction254 SubPathway254Reaction SubPathwayReaction HMDB01377 HMDB Gamma-glutamyltransferase 6 CHEBI:41721 ChEBI 977 PubChem-compound 56488-60-9 CAS Gamma-glutamyltransferase 6 CPD-3721 BioCyc HMDB00965 HMDB 5653 ChemSpider C3H7NO5S Cysteic acid 169.00449 HYPOTAURINE BioCyc C7H14N2O6S 5-L-Glutamyl-taurine 254.05725 GO:0005737 GENE ONTOLOGY Cysteine dioxygenase type 1 Q6P531 UniProt 1.0 http://identifiers.org/smpdb/SMP00013 SMPDB Cysteamine http://identifiers.org/smpdb/SMP00015 SMPDB CDO1 ADO CSAD GAD1 CSAD GAD1 GGT6 Taurine L-Cysteine Oxygen 3- Sulfinoalanine Cysteamine Carbon dioxide Oxygen Hypotaurine Carbon dioxide Carbon dioxide Cysteic acid Carbon dioxide Carbon dioxide 5-L-Glutamyl- taurine Bile Acid Biosynthesis Cysteine Metabolism Glutathione Metabolism