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6022 PubChem-compound HMDB01348 HMDB O95470 UniProt C00319 KEGG Compound 937 ChemSpider C00550 KEGG Compound DEHYDROSPHINGANINE BioCyc HMDB00252 HMDB HMDB01341 HMDB Arylsulfatase A P15289 UniProt CerP(d18:1/18:0) SPHINGO-MYELIN BioCyc HMDB04866 HMDB HMDB00024 HMDB CHEBI:17115 ChEBI HMDB00269 HMDB Sphingosine 1-phosphate 388480 ChemSpider ATP BioCyc HMDB00140 HMDB Galactosylceramide sulfotransferase 1.0 HMDB00143 HMDB 14808-79-8 CAS 1.0 SMP00034 SMPDB 1.0 ReactionCatalysis931 ACTIVATION ReactionCatalysis932 ACTIVATION ReactionCatalysis930 ACTIVATION Uridine 5'-diphosphate HMDB01565 HMDB HMDB04836 HMDB BTO:0000759 BRENDA TISSUE ONTOLOGY 1.0 HMDB01448 HMDB Adenosine diphosphate 959 ChemSpider 16755624 PubChem-compound 5742 ChemSpider 1.0 HMDB04950 HMDB CHEBI:16474 ChEBI CHEBI:27499 ChEBI 2280-44-6 CAS Alpha-galactosidase A Phosphorylcholine HMDB00122 HMDB 5736 ChemSpider 53477677 PubChem-compound 53477679 PubChem-compound 6031 PubChem-compound 1.0 HMDB01338 HMDB 133-89-1 CAS PW000157 PathWhiz 559277 ChemSpider 1.0 C00346 KEGG Compound C00588 KEGG Compound P04062 UniProt 1.0 151122-71-3 CAS SubPathwayInteraction166 SubPathway166Reaction SubPathwayReaction ReactionCatalysis872 ACTIVATION ReactionCatalysis873 ACTIVATION C9H18O8 Galactosylglycerol 254.10017 24778664 PubChem-compound 1.0 1.0 HMDB00217 HMDB Cytosol 20057277 PubChem-compound PHOSPHATIDYLCHOLINE BioCyc 1071-23-4 CAS Sphingosine-1-phosphate lyase 1 1.0 3.1.3.- false 3.1.3.- Adenosine diphosphate + Sphinganine 1-phosphate → Adenosine triphosphate + Sphinganine LEFT_TO_RIGHT 3.1.3.4 false 3.1.3.4 Sphinganine 1-phosphate + Water → Phosphate + Sphinganine LEFT_TO_RIGHT ReactionCatalysis869 ACTIVATION Uridine diphosphate glucose ReactionCatalysis868 ACTIVATION 1.0 PALMITALDEHYDE BioCyc HMDB00221 HMDB C00009 KEGG Compound C00008 KEGG Compound C00006 KEGG Compound HMDB00224 HMDB CHEBI:18009 ChEBI C00001 KEGG Compound C00005 KEGG Compound CHEBI:18367 ChEBI NADPH 1032 ChemSpider HMDB01551 HMDB CHEBI:16189 ChEBI C00002 KEGG Compound CHEBI:392583 ChEBI Lipid phosphate phosphohydrolase 1 HMDB01429 HMDB Glycine and Serine Metabolism SubPathway 1.1.1.102 false 1.1.1.102 NADPH + Sphinganine → 3-Dehydrosphinganine + NADP LEFT_TO_RIGHT 2.3.1.50 false 2.3.1.50 L-Serine + Palmityl-CoA → 3-Dehydrosphinganine + Carbon dioxide LEFT_TO_RIGHT 1.0 C19H39NO3 Dihydroceramide 329.293 BiologicalState49 388895 ChemSpider SMILES COC1=C(OC)C=C2C(=O)C(CC3CCNCC3)CC2=C1 Dihydroceramide 1.0 Sphinganine 1-phosphate BiologicalState43 C00011 KEGG Compound CHEBI:16393 ChEBI C00015 KEGG Compound 1.0 3.5.1.- false 3.5.1.- Dihydroceramide → Sphinganine LEFT_TO_RIGHT 2.7.1.138 false 2.7.1.138 Adenosine triphosphate + Ceramide (d18:1/18:0) → Adenosine diphosphate + CerP(d18:1/18:0) LEFT_TO_RIGHT 1.0 3.1.3.4 false 3.1.3.4 Phosphate + Sphingosine → Sphingosine 1-phosphate + Water LEFT_TO_RIGHT 1.0 3.5.1.23 false 3.5.1.23 Ceramide (d18:1/18:0) + Water → Sphingosine LEFT_TO_RIGHT NAD(P) BioCyc 2.7.1.91 false 2.7.1.91 Adenosine triphosphate + Sphingosine → Adenosine diphosphate + Sphingosine 1-phosphate LEFT_TO_RIGHT Sialidase-3 1.0 3.1.3.- false 3.1.3.- Adenosine diphosphate + Sphingosine 1-phosphate → Adenosine triphosphate + Sphingosine LEFT_TO_RIGHT 4.1.2.27 false 4.1.2.27 Sphingosine 1-phosphate → O-Phosphoethanolamine + Palmitaldehyde LEFT_TO_RIGHT Uridine diphosphate glucose SMP00004 SMPDB ReactionCatalysis886 ACTIVATION C00029 KEGG Compound Lactosylceramide (d18:1/12:0) 59-23-4 CAS C02686 KEGG Compound 56-65-5 CAS CHEBI:73144 ChEBI PHOSPHORYL-CHOLINE BioCyc Ceramide (d18:1/18:0) 482-67-7 CAS Serine palmitoyltransferase 2 1.0 NADP C12126 KEGG Compound ReactionCatalysis874 ACTIVATION Galabiosylceramide-sulfate Sphinganine SMILES CCCCCCCCCCCCCCCCCC(=O)N[C@@]([H])(COP(=O)(O)O)[C@]([H])(O)\C=C\CCCCCCCCCCCCC CL:0000000 CELL TYPE ONTOLOGY C00154 KEGG Compound SMILES CCCCCCCCCCCCCCCC(=O)[C@@H](N)CO 1.0 Galactocerebrosidase C01120 KEGG Compound C00031 KEGG Compound C00157 KEGG Compound 1.0 1.0 CHEBI:31488 ChEBI 104404-17-3 CAS Adenosine triphosphate SMILES CCCCCCCCCCCCC\C=C\C(O)C(N)CO 1.0 Adenosine triphosphate 5283583 PubChem-compound 1.0 Galactosylglycerol Water SMILES CCCCCCCCCCCCCCCC(=O)NC(CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)C(O)\C=C/CCCCCCCCCCCCC Arylsulfatase A Sialidase-3 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O HMDB61363 HMDB Galactosylceramide sulfotransferase SMILES CCCCCCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N SMILES CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO Water Sphinganine Ceramide glucosyltransferase SMILES CCCCCCCCCCCCC\C=C\C(O)C(N)COP(O)(O)=O C9H14N2O12P2 Uridine 5'-diphosphate 404.0022 HMDB00538 HMDB 5283588 PubChem-compound SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)C1O)NC(=O)CCCCCCCCCCC 1.0 C10H15N5O13P2S Phosphoadenosine phosphosulfate 506.98624 Glucosylceramidase CHEBI:28061 ChEBI 140102 ChemSpider CHEBI:18132 ChEBI SMILES [O-]S([O-])(=O)=O 644260 PubChem-compound SMILES NCCOP(O)(O)=O C00054 KEGG Compound C00053 KEGG Compound 16105-69-4 CAS 7732-18-5 CAS CERAMIDE BioCyc C00059 KEGG Compound 19794-97-9 CAS 1.0 Sphinganine 1-phosphate Water SMILES CCCCCCCCCCCCCCCCCCCCCC(=O)NC(CO[C@@H]1O[C@H](CO)[C@H](O[C@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)C(O)\C=C/CCCCCCCCCCCCC Alpha-galactosidase A Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 3-O-Sulfogalactosylceramide (d18:1/24:0) BiologicalState14 C10H16N5O13P3 Adenosine triphosphate 506.99576 Palmityl-CoA BiologicalState10 C00065 KEGG Compound Sphingosine kinase 2 P54803 UniProt Ceramide glucosyltransferase 10214 PubChem-compound BiologicalState18 107-73-3 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H]1O C00195 KEGG Compound 21436314 ChemSpider HMDB01967 HMDB 962 PubChem-compound GLUCOSYL_CERAMIDE BioCyc 1.0 Galactosylceramide (d18:1/16:0) 3-ketodihydrosphingosine reductase 5800 ChemSpider Sphingosine-1-phosphate lyase 1 58-98-0 CAS CO2 Carbon dioxide 43.98983 Galactosylceramide (d18:1/16:0) C05401 KEGG Compound Sphinganine C01290 KEGG Compound ReactionCatalysis908 ACTIVATION ReactionCatalysis909 ACTIVATION Sphingosine 1-phosphate ReactionCatalysis907 ACTIVATION ReactionCatalysis904 ACTIVATION BiologicalState9 ReactionCatalysis905 ACTIVATION C5H15NO4P Phosphorylcholine 184.07387 SMILES CCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO[C@@H]1O[C@H](CO)C(O)[C@H](O)[C@H]1O)[C@H](O)\C=C\CCCCCCCCCCCCC ReactionCatalysis902 ACTIVATION ReactionCatalysis903 ACTIVATION Sphingosine ReactionCatalysis900 ACTIVATION ReactionCatalysis901 ACTIVATION Glucosylceramide 5809 ChemSpider SMILES OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O BiologicalState2 1.0 1.0 14265-44-2 CAS 1.0 1.0 58-64-0 CAS 1.0 1.0 C41H78NO8P PC(15:0/18:2(9Z,12Z)) 743.5465 Q6UWV6 UniProt CHEBI:4167 ChEBI L-Serine SubPathwayOutput SMILES CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)COP(O)(O)=O C3H7NO3 L-Serine 105.042595 Serine palmitoyltransferase 1 SMILES CCCCCCCCCCCCCCCC=O Galactocerebrosidase 984 PubChem-compound Beta-1,4-galactosyltransferase 6 Beta-1,4-galactosyltransferase 6 Galactosylceramide (d18:1/16:0) 1.0 PC(15:0/18:2(9Z,12Z)) Q9UBX8 UniProt SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O 4953605 ChemSpider 22833512 PubChem-compound C01190 KEGG Compound Lipid phosphate phosphohydrolase 1 H2O Water 18.010565 990 ChemSpider Glucosylceramide Q99999 UniProt ReactionCatalysis926 ACTIVATION ReactionCatalysis927 ACTIVATION ReactionCatalysis925 ACTIVATION ReactionCatalysis922 ACTIVATION Uridine 5'-diphosphate ReactionCatalysis923 ACTIVATION CYTOLIPIN_H BioCyc 1.0 ReactionCatalysis920 ACTIVATION SMILES CCCCCCCCCCCCCCCCCC(=O)N[C@@]([H])(COP(O)(=O)OCC[N+](C)(C)C)[C@]([H])(O)\C=C\CCCCCCCCCCCCC SMILES OC[C@@H]1OC(OP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O Alkaline ceramidase 3 Q86VZ5 UniProt Ceramide kinase Phosphoadenosine phosphosulfate 1.0 Q06136 UniProt 989 ChemSpider 1.0 1.0 SM(d18:1/18:0) 1.0 5283565 PubChem-compound ReactionCatalysis910 ACTIVATION 2.7.1.91 false 2.7.1.91 Adenosine triphosphate + Sphinganine → Adenosine diphosphate + Sphinganine 1-phosphate LEFT_TO_RIGHT 1.0 17215925 ChemSpider C2H8NO4P O-Phosphoethanolamine 141.01909 PHOSPHORYL-ETHANOLAMINE BioCyc 4446696 ChemSpider Serine palmitoyltransferase 1 1014 PubChem-compound 1015 PubChem-compound O4S Sulfate 95.95173 1.0 C52H99NO13 Galabiosylceramide (d18:1/22:0) 945.7117 Ceramide (d18:1/18:0) Glucosylceramide SMILES O 656504 PubChem-compound 4.1.2.27 false 4.1.2.27 Sphinganine 1-phosphate → O-Phosphoethanolamine + Palmitaldehyde LEFT_TO_RIGHT Ceramide (d18:1/18:0) Sphinganine 1-phosphate 1.0 1.0 Serine palmitoyltransferase 2 629-80-1 CAS Sphingosine-1-phosphate phosphatase 2 D-Glucose 1.0 Q9UQ49 UniProt ADP BioCyc C10H15N5O10P2 Adenosine 3',5'-diphosphate 427.02942 PALMITYL-COA BioCyc 4446678 ChemSpider 53-59-8 CAS Lysosome Beta-galactosidase Q16880 UniProt Alkaline ceramidase 1 Q9NUN7 UniProt Phosphatidylcholine:ceramide cholinephosphotransferase 1 GO:0005829 GENE ONTOLOGY 439853 PubChem-compound 274 ChemSpider C36H71NO3 Ceramide (d18:1/18:0) 565.5434 1.0 5353955 PubChem-compound HMDB10708 HMDB 5353956 PubChem-compound Phosphate C48H93NO11S 3-O-Sulfogalactosylceramide (d18:1/24:0) 891.6469 HMDB10701 HMDB O4P Phosphate 94.95342 3-O-Sulfogalactosylceramide (d18:1/24:0) SER BioCyc Sphingosine 1.0 SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O Galabiosylceramide (d18:1/22:0) C21H30N7O17P3 NADPH 745.0911 3-5-ADP BioCyc C21H29N7O17P3 NADP 744.08325 CPD-649 BioCyc NADPH BioCyc 4682-48-8 CAS 1053-73-2 CAS CHEBI:15525 ChEBI Sphinganine 1-phosphate Alkaline ceramidase 1 Carbon dioxide 570889 ChemSpider 1.0 C15H24N2O17P2 Uridine diphosphate glucose 566.055 UDP-GLUCOSE BioCyc SMILES CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)\C=C\CCCCCCCCCCCCC SMILES [O-]P([O-])([O-])=O HMDB06790 HMDB GO:0005886 GENE ONTOLOGY 124-38-9 CAS GO:0005764 GENE ONTOLOGY C6H12O6 D-Glucose 180.06339 C41H84N2O6P SM(d18:1/18:0) 731.6067 1.0 3-ketodihydrosphingosine reductase Sphingosine kinase 2 GLC BioCyc 1.0 9799 ChemSpider SMILES CCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](OS(O)(=O)=O)[C@H]1O)[C@H](O)\C=C\CCCCCCCCCCCCC SPHINGOSINE BioCyc Q53H18 UniProt 1763-10-6 CAS Liver Lactosylceramide (d18:1/12:0) Alkaline ceramidase 3 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Adenosine triphosphate SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O 159296 PubChem-compound 53-57-6 CAS 1.0 Sphingosine kinase 2 SMILES O=C=O C18H37NO2 3-Dehydrosphinganine 299.28244 D-Galactose C36H72NO6P CerP(d18:1/18:0) 645.5097 5951 PubChem-compound C06124 KEGG Compound Ceramide kinase SMILES C[N+](C)(C)CCOP(O)(O)=O 1117 PubChem-compound Sulfate 5957 PubChem-compound 1.0 1.0 C18H37NO2 Sphingosine 299.28244 Q8TCT0 UniProt 1.0 CHEBI:15754 ChEBI C40H77NO8 Galactosylceramide (d18:1/16:0) 699.56494 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 C06125 KEGG Compound CHEBI:72961 ChEBI C06126 KEGG Compound C42H79NO13 Lactosylceramide (d18:1/12:0) 805.5551 C37H66N7O17P3S Palmityl-CoA 1005.34485 SMILES N[C@@H](CO)C(O)=O Adenosine triphosphate 1.0 C10H15N5O10P2 Adenosine diphosphate 427.02942 SMILES CCCCCCCCCCCCCCC(=O)OC[C@]([H])(COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC C18H38NO5P Sphingosine 1-phosphate 379.24875 4510275 ChemSpider C18H39NO2 Sphinganine 301.29807 4510276 ChemSpider CHEBI:17985 ChEBI CHEBI:17862 ChEBI C17H23NO3 N-acetylneuraminyl-Galactosylceramide 289.1678 C00836 KEGG Compound Beta-galactosidase Endoplasmic Reticulum Endoplasmic Reticulum Membrane 1085 ChemSpider CPD-8587 BioCyc 2-hydroxyacylsphingosine 1-beta-galactosyltransferase SMILES CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC=O CHEBI:16893 ChEBI Adenosine diphosphate HMDB06752 HMDB UDP BioCyc CHEBI:17980 ChEBI 764-22-7 CAS Phosphatidylcholine:ceramide cholinephosphotransferase 1 91486 PubChem-compound 1.0 O15270 UniProt CHEBI:17636 ChEBI 82609 ChemSpider 5675 ChemSpider Adenosine diphosphate ReactionCatalysis898 ACTIVATION 123-78-4 CAS GO:0005794 GENE ONTOLOGY ReactionCatalysis899 ACTIVATION Cell ReactionCatalysis897 ACTIVATION CHEBI:17600 ChEBI NH42SO4 BioCyc 14902 ChemSpider CHEBI:15422 ChEBI GALACTOSE BioCyc 5589 ChemSpider Serine palmitoyltransferase 1 HMDB07940 HMDB 1.0 C6H12O6 D-Galactose 180.06339 C48H93NO8 Glucosylceramide 811.6901 O15269 UniProt GALACTOSYLCERAMIDE-SULFATE BioCyc GO:0005789 GENE ONTOLOGY Q8IWX5 UniProt GO:0005783 GENE ONTOLOGY O-Phosphoethanolamine Water Q9NRA0 UniProt 85187-10-6 CAS 4446701 ChemSpider CHEBI:16526 ChEBI Galabiosylceramide-sulfate C00984 KEGG Compound CHEBI:16761 ChEBI 1.0 16744853 ChemSpider 1.0 C18H40NO5P Sphinganine 1-phosphate 381.2644 C16H32O Palmitaldehyde 240.24532 9606 TAXONOMY Palmitaldehyde PW000148 PathWhiz C02934 KEGG Compound C00517 KEGG Compound 3.2.1.23 false 3.2.1.23 Lactosylceramide (d18:1/12:0) → Glucosylceramide LEFT_TO_RIGHT 24765744 ChemSpider 24765741 ChemSpider SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OS(O)(=O)=O)[C@@H](OP(O)(O)=O)[C@H]1O Golgi apparatus HMDB01383 HMDB HMDB00295 HMDB 26993-30-6 CAS HMDB02111 HMDB PAPS BioCyc 1.0 Sphingosine-1-phosphate phosphatase 2 1.0 439357 PubChem-compound 2.4.1.80 false 2.4.1.80 Ceramide (d18:1/18:0) + Uridine diphosphate glucose → Glucosylceramide + Uridine 5'-diphosphate LEFT_TO_RIGHT 3.2.1.45 false 3.2.1.45 Glucosylceramide + Water → Ceramide (d18:1/18:0) + D-Glucose LEFT_TO_RIGHT 1.0 L-Serine 1.0 Cell Membrane CHEBI:15377 ChEBI Galactosylceramide (d18:1/16:0) Glucosylceramidase 2-hydroxyacylsphingosine 1-beta-galactosyltransferase Sphingosine-1-phosphate phosphatase 2 3-Dehydrosphinganine 56-45-1 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 5886 PubChem-compound CerP(d18:1/18:0) HMDB00061 HMDB CHEBI:17553 ChEBI 20057304 PubChem-compound HMDB00187 HMDB 1.0 280 PubChem-compound 3.2.1.46 false 3.2.1.46 Galactosylceramide (d18:1/16:0) → Ceramide (d18:1/18:0) LEFT_TO_RIGHT 3.1.4.12 false 3.1.4.12 SM(d18:1/18:0) + Water → Ceramide (d18:1/18:0) + Phosphorylcholine LEFT_TO_RIGHT 2.4.1.45 false 2.4.1.45 Ceramide (d18:1/18:0) → Galactosylceramide (d18:1/16:0) LEFT_TO_RIGHT Ceramide (d18:1/18:0) 2.7.8.27 false 2.7.8.27 Ceramide (d18:1/18:0) + PC(15:0/18:2(9Z,12Z)) → Galactosylglycerol + SM(d18:1/18:0) LEFT_TO_RIGHT 3.1.3.4 false 3.1.3.4 CerP(d18:1/18:0) + Water → Ceramide (d18:1/18:0) + Phosphate LEFT_TO_RIGHT 1.0 3.1.3.- false 3.1.3.- Ceramide (d18:1/18:0) → CerP(d18:1/18:0) LEFT_TO_RIGHT HMDB00277 HMDB 24766615 ChemSpider 5793 PubChem-compound N-acetylneuraminyl-Galactosylceramide SMILES OCC(O)CO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O 53480652 PubChem-compound 1.0 6451121 PubChem-compound O14494 UniProt HMDB01480 HMDB 1.0 Q8TDN7 UniProt 16744880 ChemSpider 1.0 Sphingolipid Metabolism 15667 PubChem-compound Galabiosylceramide (d18:1/22:0) 1061 PubChem-compound HMDB01134 HMDB CHEBI:16566 ChEBI CHEBI:60361 ChEBI CHEBI:17659 ChEBI 1.0 1.0 P06280 UniProt 1.0 HMDB00286 HMDB Reaction1221 false Lactosylceramide (d18:1/12:0) + Uridine 5'-diphosphate ← Glucosylceramide + Uridine diphosphate glucose RIGHT_TO_LEFT Adenosine diphosphate 85305-87-9 CAS Adenosine 3',5'-diphosphate 2.8.2.11 false 2.8.2.11 Galabiosylceramide (d18:1/22:0) + Phosphoadenosine phosphosulfate → Adenosine 3',5'-diphosphate + Galabiosylceramide-sulfate LEFT_TO_RIGHT Q16739 UniProt 3.2.1.18 false 3.2.1.18 Galactosylceramide (d18:1/16:0) → N-acetylneuraminyl-Galactosylceramide LEFT_TO_RIGHT Glucosylceramide 3.2.1.22 false 3.2.1.22 D-Galactose + Galactosylceramide (d18:1/16:0) ← Galabiosylceramide (d18:1/22:0) RIGHT_TO_LEFT 77538-38-6 CAS 2.8.2.11 false 2.8.2.11 Galactosylceramide (d18:1/16:0) + Phosphoadenosine phosphosulfate → 3-O-Sulfogalactosylceramide (d18:1/24:0) + Adenosine 3',5'-diphosphate LEFT_TO_RIGHT 3.1.6.8 false 3.1.6.8 3-O-Sulfogalactosylceramide (d18:1/24:0) + Water → Galactosylceramide (d18:1/16:0) + Sulfate LEFT_TO_RIGHT Serine palmitoyltransferase 2 Serine palmitoyltransferase 1 3- ketodihydrosphingosine reductase Sphingosine kinase 2 Sphingosine- 1-phosphate phosphatase 2 Lipid phosphate phosphohydrolase 1 Sphingosine- 1-phosphate lyase 1 Sphingolipid delta(4)- desaturase/C4- hydroxylase DES2 Sphingosine- 1-phosphate lyase 1 Sphingosine kinase 2 Sphingosine- 1-phosphate phosphatase 2 Lipid phosphate phosphohydrolase 1 Alkaline ceramidase 1 Ceramide kinase Lipid phosphate phosphohydrolase 1 Sphingosine- 1-phosphate phosphatase 2 Phosphatidylcholine:ceramide cholinephosphotransferase 1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 2- hydroxyacylsphingosine 1-beta- galactosyltransferase Galactocerebrosidase Glucosylceramidase Ceramide glucosyltransferase Beta- galactosidase Beta-1,4- galactosyltransferase 6 Galactosylceramide sulfotransferase Arylsulfatase A Alpha- galactosidase A Galactosylceramide sulfotransferase Sialidase-3 Alkaline ceramidase 3 L-Serine Palmityl-CoA 3-Dehydrosphinganine Sphinganine NADPH