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CHEBI:16015 ChEBI Purine nucleoside phosphorylase 7722-84-1 CAS 6022 PubChem-compound 1.0 937 ChemSpider HMDB00250 HMDB HMDB01341 HMDB 439153 PubChem-compound 13553 ChemSpider 4.0 Nicotinate and Nicotinamide Metabolism 145043 ChemSpider CHEBI:16027 ChEBI HMDB00148 HMDB ATP BioCyc P40261 UniProt CHEBI:17111 ChEBI SMILES CN1C=CC(=O)C(=C1)C(N)=O 559142 ChemSpider 1.0 165491 PubChem-compound SMILES CN1C=C(C=CC1=O)C(N)=O NAD HMDB00232 HMDB C15H23N6O5S S-Adenosylmethionine 399.14505 5746 ChemSpider NICOTINATE_NUCLEOTIDE BioCyc 1.0 5742 ChemSpider C03722 KEGG Compound PW000163 PathWhiz C00455 KEGG Compound CHEBI:16474 ChEBI RIBOSE-1-ARSENATE BioCyc 952 ChemSpider SMILES NC(=O)C1=CC=CN=C1 7540-64-9 CAS HMDB59597 HMDB HMDB00229 HMDB SMP00048 SMPDB CHEBI:18304 ChEBI 5858 ChemSpider 389671 ChemSpider 1.0 1.0 CHEBI:16240 ChEBI PW000151 PathWhiz 1010 ChemSpider PPI BioCyc 938 PubChem-compound 936 PubChem-compound C00119 KEGG Compound 1.0 HMDB00699 HMDB C5H10N2O3 L-Glutamine 146.06914 Water HMDB00217 HMDB SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12 979-92-0 CAS CHEBI:16171 ChEBI 1.0 Cytosol Peroxisomal NADH pyrophosphatase NUDT12 1.0 C14H20N6O5S S-Adenosylhomocysteine 384.12158 1.0 7664-38-2 CAS 2.7.1.23 false 2.7.1.23 Adenosine triphosphate + NAD → Adenosine diphosphate + NADP LEFT_TO_RIGHT C00009 KEGG Compound HMDB00221 HMDB 1037 ChemSpider C00008 KEGG Compound C00007 KEGG Compound C00006 KEGG Compound CHEBI:18009 ChEBI Hydrogen Ion C00001 KEGG Compound ADP-ribosyl cyclase 2 CHEBI:18361 ChEBI C00005 KEGG Compound CHEBI:18367 ChEBI C00004 KEGG Compound Nicotinamide phosphoribosyltransferase 1032 ChemSpider C00003 KEGG Compound CHEBI:17154 ChEBI C00002 KEGG Compound Glutamine-dependent NAD(+) synthetase Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 Q6IA69 UniProt HMDB01429 HMDB C00019 KEGG Compound C21H28N7O14P2 NAD 664.11694 C00011 KEGG Compound C00253 KEGG Compound 7339 PubChem-compound 913 ChemSpider 911 ChemSpider C00013 KEGG Compound QUINOLINATE BioCyc NAD(P) BioCyc Aldehyde oxidase 141636 ChemSpider Q10588 UniProt 1.0 H Hydrogen Ion 1.007825 388301 ChemSpider SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)[N+]4=CC=CC(=C4)C(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 Cytosolic purine 5'-nucleotidase 56-65-5 CAS C00021 KEGG Compound N1-Methyl-2-pyridone-5-carboxamide 53-84-9 CAS C00020 KEGG Compound C00027 KEGG Compound SMILES NC1=C2N=CN(C3OC(COP(O)(=O)OP(O)(=O)OCC4OC(O)C(O)C4O)C(O)C3O)C2=NC=N1 L-Glutamic acid C00025 KEGG Compound CHEBI:26078 ChEBI HMDB01406 HMDB Tryptophan Metabolism SubPathway NADP CL:0000000 CELL TYPE ONTOLOGY C05843 KEGG Compound C00153 KEGG Compound C05842 KEGG Compound C05841 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Nicotinamide ribotide AMP BioCyc Peroxisome HYDROGEN-PEROXIDE BioCyc SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H]1O SMILES OC(=O)C1=CN=CC=C1 1094-61-7 CAS C7H9N2O 1-Methylnicotinamide 137.07149 SMILES [O-]P([O-])(=O)OP([O-])([O-])=O N1-Methyl-4-pyridone-3-carboxamide 56-85-9 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 763 ChemSpider ADENOSINE_DIPHOSPHATE_RIBOSE BioCyc 7062 ChemSpider Nicotinic acid mononucleotide HMDB00538 HMDB 1.0 C11H15N2O5 Nicotinamide riboside 255.0981 784 PubChem-compound 53477721 PubChem-compound C11H16NO9P Nicotinic acid mononucleotide 337.05627 Q15274 UniProt C11H14NO6 Nicotinate D-ribonucleoside 256.08212 7732-18-5 CAS NIACINAMIDE BioCyc Ribose-1-arsenate SMILES NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O NAD 61-19-8 CAS Nicotinamide N-methyltransferase SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 NICOTINAMIDE_RIBOSE BioCyc SMILES OC(=O)C1=CC=CN=C1C(O)=O 56-86-0 CAS NAD HMDB00641 HMDB C10H16N5O13P3 Adenosine triphosphate 506.99576 Phosphoric acid C00064 KEGG Compound Adenosine monophosphate Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.0 Nicotinamide mononucleotide adenylyltransferase 2 Nicotinate-nucleotide pyrophosphorylase [carboxylating] S-Adenosylhomocysteine HMDB01967 HMDB 962 PubChem-compound 31983 ChemSpider Nicotinamide ribotide 388956 ChemSpider HMDB00855 HMDB 5800 ChemSpider Nicotinamide riboside Hydrogen peroxide CO2 Carbon dioxide 43.98983 979 ChemSpider NAD kinase 6450-77-7 CAS C00080 KEGG Compound SMILES O=O H3O4P Phosphoric acid 97.9769 BiologicalState5 BiologicalState3 SMILES N[C@@H](CCC(O)=O)C(O)=O 1341-23-7 CAS BiologicalState2 14265-44-2 CAS 58-64-0 CAS Q06278 UniProt 62899 ChemSpider 3.0 1.0 NADP 2.0 1.0 C01185 KEGG Compound Phosphoribosyl pyrophosphate CHEBI:15927 ChEBI Peroxisomal NADH pyrophosphatase NUDT12 644102 PubChem-compound Aldehyde oxidase 6083 PubChem-compound CPD-396 BioCyc SMILES OCC1OC(O[As](O)(O)=O)C(O)C1O 22833512 PubChem-compound 25246222 PubChem-compound 1.0 1.0 CHEBI:18050 ChEBI Q9NWW6 UniProt HMDB04193 HMDB H2O Water 18.010565 HMDB04194 HMDB H2O2 Hydrogen peroxide 34.005478 SMILES O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O Niacinamide NADH BioCyc NAD BioCyc 29908-03-0 CAS NAD(P) transhydrogenase, mitochondrial 977 PubChem-compound NADPH 769-49-3 CAS 1.0 1.0 1.0 1.0 NAD kinase NIACINE BioCyc Nicotinamide N-methyltransferase 1.0 439924 PubChem-compound Nicotinamide mononucleotide adenylyltransferase 2 30572 ChemSpider 17215925 ChemSpider Nicotinamide riboside kinase 1 RIBOSE-1P BioCyc 2.0 1.0 Adenosine monophosphate SMILES O SMILES OO C03150 KEGG Compound C7H5NO4 Quinolinic acid 167.02185 C11H15N2O8P Nicotinamide ribotide 334.0566 C10H14N5O7P Adenosine monophosphate 347.06308 1.0 1004 PubChem-compound 1.0 5961 PubChem-compound 440810 PubChem-compound CHEBI:15846 ChEBI ADP BioCyc HMDB00939 HMDB P00491 UniProt CHEBI:15940 ChEBI 53-59-8 CAS 1038 PubChem-compound GO:0005829 GENE ONTOLOGY 3106-60-3 CAS 25201247 PubChem-compound SMILES C[N+]1=CC=CC(=C1)C(N)=O 274 ChemSpider 2.1.1.1 false 2.1.1.1 Niacinamide + S-Adenosylmethionine → 1-Methylnicotinamide + S-Adenosylhomocysteine LEFT_TO_RIGHT HMDB00902 HMDB CHEBI:16908 ChEBI ADENOSYL-HOMO-CYS BioCyc Pyrophosphate O4P Phosphate 94.95342 1.0 Glutamine-dependent NAD(+) synthetase 1-Methylnicotinamide ADP-ribosyl cyclase 2 NAD(P) transhydrogenase, mitochondrial 161234 PubChem-compound SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O C21H30N7O17P3 NADPH 745.0911 Mitochondrion C21H29N7O17P3 NADP 744.08325 NADPH BioCyc Nicotinic acid CHEBI:15763 ChEBI Adenosine diphosphate ribose CHEBI:27748 ChEBI Carbon dioxide CPD-6641 BioCyc 58-68-4 CAS C5H13O14P3 Phosphoribosyl pyrophosphate 389.9518 SMILES [O-]P([O-])([O-])=O C5H11AsO8 Ribose-1-arsenate 273.96698 1.0 124-38-9 CAS CHEBI:15414 ChEBI 1.0 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O 444 ChemSpider SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O GLN BioCyc GLT BioCyc Nicotinate-nucleotide pyrophosphorylase [carboxylating] 53-57-6 CAS 1.0 SMILES O=C=O S-ADENOSYLMETHIONINE BioCyc SMILES OP(O)(O)=O O7P2 Pyrophosphate 173.91193 C21H29N7O14P2 NADH 665.12476 C6H5NO2 Nicotinic acid 123.03203 C5H11O8P Ribose 1-phosphate 230.01915 5957 PubChem-compound 457 PubChem-compound CHEBI:16960 ChEBI CHEBI:27838 ChEBI 1.0 14180 PubChem-compound Adenosine triphosphate GO:0005739 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 Q9BQG2 UniProt HMDB03125 HMDB Purine nucleoside phosphorylase Cytosolic purine 5'-nucleotidase Nicotinamide riboside kinase 1 CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O HMDB01185 HMDB 5682 ChemSpider 2.4.2.1 false 2.4.2.1 Niacinamide + Ribose-1-arsenate → Nicotinamide riboside + Phosphoric acid LEFT_TO_RIGHT P49902 UniProt C6H6N2O Niacinamide 122.04801 2.4.2.1 false 2.4.2.1 Nicotinate D-ribonucleoside + Phosphoric acid → Hydrogen Ion + Nicotinic acid + Ribose 1-phosphate LEFT_TO_RIGHT ReactionCatalysis2130 ACTIVATION ReactionCatalysis1040 ACTIVATION ReactionCatalysis1043 ACTIVATION ReactionCatalysis2132 ACTIVATION ReactionCatalysis2131 ACTIVATION ReactionCatalysis1045 ACTIVATION ReactionCatalysis2133 ACTIVATION ReactionCatalysis1044 ACTIVATION ReactionCatalysis1047 ACTIVATION 14000-31-8 CAS ReactionCatalysis1046 ACTIVATION Peroxisomal NADH pyrophosphatase NUDT12 CHEBI:16300 ChEBI P43490 UniProt 5675 ChemSpider S-Adenosylmethionine P22413 UniProt Adenosine diphosphate 1.0 NICOTINAMIDE_NUCLEOTIDE BioCyc 1.0 Cell 14075-00-4 CAS CHEBI:15422 ChEBI C00857 KEGG Compound 388299 ChemSpider 1.0 89-00-9 CAS CHEBI:27410 ChEBI O2 Oxygen 31.98983 69698 PubChem-compound 3.2.2.6 false 3.2.2.6 Adenosine diphosphate ribose + Niacinamide ↔ NAD + Water REVERSIBLE Reaction1317 false NAD + Water ↔ Adenosine monophosphate + Nicotinamide ribotide REVERSIBLE 2.4.2.12 false 2.4.2.12 Niacinamide + Phosphoribosyl pyrophosphate ↔ Nicotinamide ribotide + Pyrophosphate REVERSIBLE Purine nucleoside phosphorylase C02918 KEGG Compound 3.2.2.6 false 3.2.2.6 Adenosine diphosphate ribose + Niacinamide + Phosphate ↔ NADP + Water REVERSIBLE 1.6.1.2 false 1.6.1.2 NAD + NADPH → NADH + NADP LEFT_TO_RIGHT Water C5H9NO4 L-Glutamic acid 147.05316 HMDB01179 HMDB 33032 PubChem-compound HMDB01178 HMDB Reaction1309 false NAD + Pyrophosphate → Adenosine triphosphate + Nicotinamide ribotide LEFT_TO_RIGHT 3.6.1.22 false 3.6.1.22 NAD + Water → Adenosine monophosphate + Nicotinamide ribotide LEFT_TO_RIGHT 1.0 CHEBI:16526 ChEBI 2.0 59-67-6 CAS HMDB02142 HMDB C00620 KEGG Compound CHEBI:16761 ChEBI 7782-44-7 CAS 3.1.3.5 false 3.1.3.5 Nicotinamide riboside + Phosphate → Nicotinamide ribotide + Water LEFT_TO_RIGHT Nicotinic acid adenine dinucleotide GO:0005777 GENE ONTOLOGY 1.0 Reaction1301 false 1-Methylnicotinamide + Oxygen + Water → Hydrogen peroxide + N1-Methyl-4-pyridone-3-carboxamide LEFT_TO_RIGHT Q13423 UniProt NADH 9606 TAXONOMY 1.0 SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)([O-])=O)[N+]1=CC=CC(C1)C(O)=O SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)[N+]1=CC(=CC=C1)C(O)=O 5893 PubChem-compound HMDB02111 HMDB NAD(P) transhydrogenase, mitochondrial 2.4.2.19 false 2.4.2.19 Carbon dioxide + Nicotinic acid mononucleotide + Pyrophosphate → Phosphoribosyl pyrophosphate + Quinolinic acid LEFT_TO_RIGHT 3.1.3.5 false 3.1.3.5 Nicotinic acid mononucleotide + Water → Nicotinate D-ribonucleoside + Phosphate LEFT_TO_RIGHT HMDB12285 HMDB 439236 PubChem-compound 701-44-0 CAS 1.0 1.0 SMP00063 SMPDB Reaction1332 false Adenosine triphosphate + Nicotinate D-ribonucleoside → Adenosine diphosphate + Nicotinic acid mononucleotide LEFT_TO_RIGHT CHEBI:15377 ChEBI CHEBI:15379 ChEBI SubPathwayInteraction189 SubPathway189Reaction SubPathwayReaction 1.0 Nicotinamide phosphoribosyltransferase CHEBI:15378 ChEBI SMILES [H+] 3.6.1.22 false 3.6.1.22 Nicotinic acid adenine dinucleotide + Water → 2 Nicotinic acid mononucleotide LEFT_TO_RIGHT Quinolinic acid SubPathwayInput SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Nicotinate D-ribonucleoside 5886 PubChem-compound C21H27N6O15P2 Nicotinic acid adenine dinucleotide 665.10095 C15H23N5O14P2 Adenosine diphosphate ribose 559.07166 ReactionCatalysis1016 ACTIVATION Phosphate Oxygen 280 PubChem-compound Reaction1328 false Adenosine triphosphate + Nicotinic acid mononucleotide → Nicotinic acid adenine dinucleotide + Pyrophosphate LEFT_TO_RIGHT 3.6.1.22 false 3.6.1.22 Nicotinic acid adenine dinucleotide + Water → Adenosine monophosphate + Nicotinic acid mononucleotide LEFT_TO_RIGHT 6.3.5.1 false 6.3.5.1 Adenosine triphosphate + L-Glutamine + Nicotinic acid adenine dinucleotide + Water → Adenosine monophosphate + L-Glutamic acid + NAD + Pyrophosphate LEFT_TO_RIGHT HMDB01487 HMDB CHEBI:16675 ChEBI HMDB01489 HMDB CHEBI:16797 ChEBI L-Glutamine HMDB01488 HMDB Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 388373 ChemSpider SMILES N[C@@H](CCC(N)=O)C(O)=O SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12)C(O)=O PRPP BioCyc ReactionCatalysis1028 ACTIVATION 192 PubChem-compound HMDB06809 HMDB 1.0 ReactionCatalysis1020 ACTIVATION Cytosolic purine 5'-nucleotidase ReactionCatalysis1022 ACTIVATION ReactionCatalysis1025 ACTIVATION ReactionCatalysis1024 ACTIVATION Ribose 1-phosphate HMDB01377 HMDB HMDB00045 HMDB 1061 PubChem-compound Reaction107 false 1-Methylnicotinamide + Oxygen + Water → Hydrogen peroxide + N1-Methyl-2-pyridone-5-carboxamide LEFT_TO_RIGHT HMDB00280 HMDB CHEBI:16680 ChEBI C00301 KEGG Compound O95544 UniProt 1066 PubChem-compound HMDB01132 HMDB 24762165 PubChem-compound C7H8N2O2 N1-Methyl-2-pyridone-5-carboxamide 152.05858 C7H8N2O2 N1-Methyl-4-pyridone-3-carboxamide 152.05858 ReactionCatalysis1037 ACTIVATION ReactionCatalysis2129 ACTIVATION Q9BZQ4 UniProt DEAMIDO-NAD BioCyc 187 ChemSpider 98-92-0 CAS 20762-30-5 CAS ReactionCatalysis1030 ACTIVATION 1.0 ReactionCatalysis1032 ACTIVATION ReactionCatalysis1031 ACTIVATION 321-02-8 CAS Nicotinamide N- methyltransferase Aldehyde oxidase Aldehyde oxidase Purine nucleoside phosphorylase Cytosolic purine 5'-nucleotidase Nicotinamide phosphoribosyltransferase ADP-ribosyl cyclase 2 ADP-ribosyl cyclase 2 Peroxisomal NADH pyrophosphatase NUDT12 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 Nicotinamide mononucleotide adenylyltransferase 2 NAD(P) transhydrogenase, mitochondrial NAD kinase Glutamine- dependent NAD(+) synthetase Peroxisomal NADH pyrophosphatase NUDT12 Nicotinamide mononucleotide adenylyltransferase 2 Nicotinamide riboside kinase 1 Cytosolic purine 5'-nucleotidase Purine nucleoside phosphorylase Nicotinate- nucleotide pyrophosphorylase [carboxylating] Peroxisomal NADH pyrophosphatase NUDT12 Quinolinic acid S-Adenosylmethionine Niacinamide S-Adenosylhomocysteine 1- Methylnicotinamide O 2 H 2 O N1-Methyl-2- pyridone-5- carboxamide H 2 O 2 H 2 O O 2 N1-Methyl-4- pyridone-3- carboxamide H 2 O 2 Ribose-1- arsenate Nicotinamide riboside Phosphoric acid P i Nicotinamide ribotide H 2 O Phosphoribosyl pyrophosphate PP i P i Adenosine diphosphate ribose NADP H 2 O Adenosine diphosphate ribose NAD H 2 O H 2 O AMP H 2 O AMP PP i ATP NADPH NADH ATP ADP Nicotinic acid adenine dinucleotide ATP H 2 O L-Glutamine AMP PP i L-Glutamic acid H 2 O Nicotinic acid mononucleotide AMP ATP PP i Nicotinate D-ribonucleoside ATP ADP H 2 O P i P i Nicotinic acid Ribose 1-phosphate H + PP i CO 2 Phosphoribosyl pyrophosphate H 2 O FAD Molybdopterin 2Fe-2S FAD Molybdopterin 2Fe-2S Magnesium Magnesium Magnesium Magnesium Magnesium Magnesium Magnesium Magnesium Tryptophan Metabolism Peroxisome Mitochondrion Intracellular Space Extracellular Space Peroxisome
CHEBI:16015 ChEBI Purine nucleoside phosphorylase 7722-84-1 CAS 6022 PubChem-compound 1.0 937 ChemSpider HMDB00250 HMDB HMDB01341 HMDB 439153 PubChem-compound 13553 ChemSpider 4.0 Nicotinate and Nicotinamide Metabolism 145043 ChemSpider CHEBI:16027 ChEBI HMDB00148 HMDB ATP BioCyc P40261 UniProt CHEBI:17111 ChEBI SMILES CN1C=CC(=O)C(=C1)C(N)=O 559142 ChemSpider 1.0 165491 PubChem-compound SMILES CN1C=C(C=CC1=O)C(N)=O NAD HMDB00232 HMDB C15H23N6O5S S-Adenosylmethionine 399.14505 5746 ChemSpider NICOTINATE_NUCLEOTIDE BioCyc 1.0 5742 ChemSpider C03722 KEGG Compound PW000163 PathWhiz C00455 KEGG Compound CHEBI:16474 ChEBI RIBOSE-1-ARSENATE BioCyc 952 ChemSpider SMILES NC(=O)C1=CC=CN=C1 7540-64-9 CAS HMDB59597 HMDB HMDB00229 HMDB http://identifiers.org/smpdb/SMP00048 SMPDB CHEBI:18304 ChEBI 5858 ChemSpider 389671 ChemSpider 1.0 1.0 CHEBI:16240 ChEBI PW000151 PathWhiz 1010 ChemSpider PPI BioCyc 938 PubChem-compound 936 PubChem-compound C00119 KEGG Compound 1.0 HMDB00699 HMDB C5H10N2O3 L-Glutamine 146.06914 Water HMDB00217 HMDB SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12 979-92-0 CAS CHEBI:16171 ChEBI 1.0 Cytosol Peroxisomal NADH pyrophosphatase NUDT12 1.0 C14H20N6O5S S-Adenosylhomocysteine 384.12158 1.0 7664-38-2 CAS 2.7.1.23 false 2.7.1.23 Adenosine triphosphate + NAD → Adenosine diphosphate + NADP LEFT_TO_RIGHT C00009 KEGG Compound HMDB00221 HMDB 1037 ChemSpider C00008 KEGG Compound C00007 KEGG Compound C00006 KEGG Compound CHEBI:18009 ChEBI Hydrogen Ion C00001 KEGG Compound ADP-ribosyl cyclase 2 CHEBI:18361 ChEBI C00005 KEGG Compound CHEBI:18367 ChEBI C00004 KEGG Compound Nicotinamide phosphoribosyltransferase 1032 ChemSpider C00003 KEGG Compound CHEBI:17154 ChEBI C00002 KEGG Compound Glutamine-dependent NAD(+) synthetase Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 Q6IA69 UniProt HMDB01429 HMDB C00019 KEGG Compound C21H28N7O14P2 NAD 664.11694 C00011 KEGG Compound C00253 KEGG Compound 7339 PubChem-compound 913 ChemSpider 911 ChemSpider C00013 KEGG Compound QUINOLINATE BioCyc NAD(P) BioCyc Aldehyde oxidase 141636 ChemSpider Q10588 UniProt 1.0 H Hydrogen Ion 1.007825 388301 ChemSpider SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)[N+]4=CC=CC(=C4)C(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 Cytosolic purine 5'-nucleotidase 56-65-5 CAS C00021 KEGG Compound N1-Methyl-2-pyridone-5-carboxamide 53-84-9 CAS C00020 KEGG Compound C00027 KEGG Compound SMILES NC1=C2N=CN(C3OC(COP(O)(=O)OP(O)(=O)OCC4OC(O)C(O)C4O)C(O)C3O)C2=NC=N1 L-Glutamic acid C00025 KEGG Compound CHEBI:26078 ChEBI HMDB01406 HMDB Tryptophan Metabolism SubPathway NADP CL:0000000 CELL TYPE ONTOLOGY C05843 KEGG Compound C00153 KEGG Compound C05842 KEGG Compound C05841 KEGG Compound SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Nicotinamide ribotide AMP BioCyc Peroxisome HYDROGEN-PEROXIDE BioCyc SMILES OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H]1O SMILES OC(=O)C1=CN=CC=C1 1094-61-7 CAS C7H9N2O 1-Methylnicotinamide 137.07149 SMILES [O-]P([O-])(=O)OP([O-])([O-])=O N1-Methyl-4-pyridone-3-carboxamide 56-85-9 CAS SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 763 ChemSpider ADENOSINE_DIPHOSPHATE_RIBOSE BioCyc 7062 ChemSpider Nicotinic acid mononucleotide HMDB00538 HMDB 1.0 C11H15N2O5 Nicotinamide riboside 255.0981 784 PubChem-compound 53477721 PubChem-compound C11H16NO9P Nicotinic acid mononucleotide 337.05627 Q15274 UniProt C11H14NO6 Nicotinate D-ribonucleoside 256.08212 7732-18-5 CAS NIACINAMIDE BioCyc Ribose-1-arsenate SMILES NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O NAD 61-19-8 CAS Nicotinamide N-methyltransferase SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 NICOTINAMIDE_RIBOSE BioCyc SMILES OC(=O)C1=CC=CN=C1C(O)=O 56-86-0 CAS NAD HMDB00641 HMDB C10H16N5O13P3 Adenosine triphosphate 506.99576 Phosphoric acid C00064 KEGG Compound Adenosine monophosphate Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 1.0 Nicotinamide mononucleotide adenylyltransferase 2 Nicotinate-nucleotide pyrophosphorylase [carboxylating] S-Adenosylhomocysteine HMDB01967 HMDB 962 PubChem-compound 31983 ChemSpider Nicotinamide ribotide 388956 ChemSpider HMDB00855 HMDB 5800 ChemSpider Nicotinamide riboside Hydrogen peroxide CO2 Carbon dioxide 43.98983 979 ChemSpider NAD kinase 6450-77-7 CAS C00080 KEGG Compound SMILES O=O H3O4P Phosphoric acid 97.9769 BiologicalState5 Homo sapiens, Cell, Peroxisome BiologicalState3 Homo sapiens, Cell, Mitochondrion SMILES N[C@@H](CCC(O)=O)C(O)=O 1341-23-7 CAS BiologicalState2 Homo sapiens, Cell, Cytosol 14265-44-2 CAS 58-64-0 CAS Q06278 UniProt 62899 ChemSpider 3.0 1.0 NADP 2.0 1.0 C01185 KEGG Compound Phosphoribosyl pyrophosphate CHEBI:15927 ChEBI Peroxisomal NADH pyrophosphatase NUDT12 644102 PubChem-compound Aldehyde oxidase 6083 PubChem-compound CPD-396 BioCyc SMILES OCC1OC(O[As](O)(O)=O)C(O)C1O 22833512 PubChem-compound 25246222 PubChem-compound 1.0 1.0 CHEBI:18050 ChEBI Q9NWW6 UniProt HMDB04193 HMDB H2O Water 18.010565 HMDB04194 HMDB H2O2 Hydrogen peroxide 34.005478 SMILES O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O Niacinamide NADH BioCyc NAD BioCyc 29908-03-0 CAS NAD(P) transhydrogenase, mitochondrial 977 PubChem-compound NADPH 769-49-3 CAS 1.0 1.0 1.0 1.0 NAD kinase NIACINE BioCyc Nicotinamide N-methyltransferase 1.0 439924 PubChem-compound Nicotinamide mononucleotide adenylyltransferase 2 30572 ChemSpider 17215925 ChemSpider Nicotinamide riboside kinase 1 RIBOSE-1P BioCyc 2.0 1.0 Adenosine monophosphate SMILES O SMILES OO C03150 KEGG Compound C7H5NO4 Quinolinic acid 167.02185 C11H15N2O8P Nicotinamide ribotide 334.0566 C10H14N5O7P Adenosine monophosphate 347.06308 1.0 1004 PubChem-compound 1.0 5961 PubChem-compound 440810 PubChem-compound CHEBI:15846 ChEBI ADP BioCyc HMDB00939 HMDB P00491 UniProt CHEBI:15940 ChEBI 53-59-8 CAS 1038 PubChem-compound GO:0005829 GENE ONTOLOGY 3106-60-3 CAS 25201247 PubChem-compound SMILES C[N+]1=CC=CC(=C1)C(N)=O 274 ChemSpider 2.1.1.1 false 2.1.1.1 Niacinamide + S-Adenosylmethionine → 1-Methylnicotinamide + S-Adenosylhomocysteine LEFT_TO_RIGHT HMDB00902 HMDB CHEBI:16908 ChEBI ADENOSYL-HOMO-CYS BioCyc Pyrophosphate O4P Phosphate 94.95342 1.0