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CHEBI:16015 ChEBI Glutathione synthetase HMDB00254 HMDB CH2O3 Carbonic acid 62.000393 388356 ChemSpider CHEBI:17345 ChEBI 6022 PubChem-compound Q9UI32 UniProt C23H38N7O17P3S Acetyl-CoA 809.1258 1.0 937 ChemSpider 1.0 CYS BioCyc HMDB00250 HMDB CHEBI:16134 ChEBI HMDB01341 HMDB C8H14N2O5S Gamma-Glutamylcysteine 250.06235 1.0 L-Aspartic acid Glutathione reductase, mitochondrial 439153 PubChem-compound Succinic acid 50 ChemSpider 1.0 SMP00020 SMPDB 85-32-5 CAS CHEBI:16027 ChEBI HMDB00148 HMDB HMDB03538 HMDB OXALACETIC_ACID BioCyc ATP BioCyc tRNA(Glu) 3.0 2.0 PW000052 PathWhiz CHEBI:17111 ChEBI CHEBI:16265 ChEBI C8H16NO9P N-Acetyl-D-Glucosamine 6-Phosphate 301.05627 Aspartate aminotransferase, mitochondrial Alanine aminotransferase 1 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial 559142 ChemSpider SubPathwayInteraction140 SubPathway140Reaction SubPathwayReaction HMDB00112 HMDB PW000043 PathWhiz 5746 ChemSpider HMDB01206 HMDB 5745 ChemSpider 5742 ChemSpider C00334 KEGG Compound 2.0 L-ASPARTATE BioCyc PW000162 PathWhiz CHEBI:17561 ChEBI CHEBI:16474 ChEBI PW000160 PathWhiz 950 ChemSpider 7540-64-9 CAS Carbon dioxide HMDB59597 HMDB SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 SMP00046 SMPDB SMP00044 SMPDB L-Glutamic acid 5858 ChemSpider HMDB00243 HMDB 1.0 HMDB00123 HMDB HMDB00124 HMDB Adenosine monophosphate HMDB00125 HMDB 5735 ChemSpider 1.0 C00461 KEGG Compound 945 ChemSpider 2.0 1010 ChemSpider 1.0 SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS 2.0 SMP00050 SMPDB 1.0 PPI BioCyc 1-Pyrroline-5-carboxylic acid SubPathwayInput SMP00059 SMPDB C00119 KEGG Compound CHEBI:17029 ChEBI HMDB00574 HMDB 1.0 HMDB01423 HMDB HMDB01301 HMDB C5H10N2O3 L-Glutamine 146.06914 Probable glutamate--tRNA ligase, mitochondrial CH4NO5P Carbamoyl phosphate 140.98271 HMDB00217 HMDB C00232 KEGG Compound L-Glutamic acid SubPathwayOutput SubPathwayInput C00352 KEGG Compound 124886 PubChem-compound C00357 KEGG Compound Amidophosphoribosyltransferase SUC BioCyc Adenosine triphosphate Q99259 UniProt 7664-38-2 CAS HMDB00208 HMDB 3.0 Fructose 6-phosphate C00009 KEGG Compound CAD protein 1159 ChemSpider HMDB00221 HMDB C00008 KEGG Compound 3616-42-0 CAS HMDB00223 HMDB HMDB01554 HMDB C00127 KEGG Compound C00006 KEGG Compound 1.0 CHEBI:18009 ChEBI C00001 KEGG Compound L-ALPHA-ALANINE BioCyc CHEBI:18361 ChEBI Carbonic acid 56-41-7 CAS C00005 KEGG Compound CHEBI:18367 ChEBI C00004 KEGG Compound 1032 ChemSpider C00003 KEGG Compound C20H32N6O12S2 Oxidized glutathione 612.152 C00002 KEGG Compound 1031 ChemSpider 73323 PubChem-compound 2.0 1.0 66054 ChemSpider Carbamoyl-phosphate synthase [ammonia], mitochondrial HMDB01429 HMDB C5H12NO7P 5-Phosphoribosylamine 229.03514 Glutamate dehydrogenase 1, mitochondrial 945257 INSDC Carbamoyl phosphate SubPathwayInteraction137 SubPathwayReaction SubPathway137Reaction SubPathwayInteraction139 SubPathway139Reaction SubPathwayReaction 1.0 C21H28N7O14P2 NAD 664.11694 SubPathwayInteraction138 SubPathway138Reaction SubPathwayReaction 44367445 PubChem-compound Adenosine triphosphate C00011 KEGG Compound Glutamate--cysteine ligase catalytic subunit 7339 PubChem-compound 1.0 C00010 KEGG Compound 1.0 FRUCTOSE-6P BioCyc C00014 KEGG Compound 2.0 C00013 KEGG Compound C6H14NO8P Glucosamine 6-phosphate 259.04572 Succinate-semialdehyde dehydrogenase, mitochondrial A8YXX4 UniProt NAD(P) BioCyc Guanosine monophosphate 4-aminobutyrate aminotransferase, mitochondrial D-GLUCOSAMINE-6-P BioCyc Pyruvic acid H Hydrogen Ion 1.007825 Carbamoyl phosphate SubPathwayInput C4H6O3 Succinic acid semialdehyde 102.03169 C00144 KEGG Compound C01353 KEGG Compound C00022 KEGG Compound L-Glutamine 56-65-5 CAS C00020 KEGG Compound 53-84-9 CAS 5653 ChemSpider SMILES NC1=C2N=CN(C3OC(COP(O)(=O)OP(O)(=O)OCC4OC(O)C(O)C4O)C(O)C3O)C2=NC=N1 C00026 KEGG Compound C00025 KEGG Compound 62713 ChemSpider C00024 KEGG Compound CHEBI:26078 ChEBI N-Acetyl-D-Glucosamine 6-Phosphate 5-Phosphoribosylamine SubPathwayInput Glutamate--cysteine ligase regulatory subunit Glutamate--cysteine ligase catalytic subunit SMP00015 SMPDB 6.3.1.2 false 6.3.1.2 Adenosine triphosphate + Ammonia + L-Glutamic acid → Adenosine diphosphate + L-Glutamine + Phosphate LEFT_TO_RIGHT OXIDIZED-GLUTATHIONE BioCyc Reaction39 false Gamma-Aminobutyric acid + Oxoglutaric acid ↔ L-Glutamic acid + Succinic acid semialdehyde REVERSIBLE 1.4.1.3 false 1.4.1.3 L-Glutamic acid + NAD + Water → Ammonia + NADH + Oxoglutaric acid LEFT_TO_RIGHT Glutamine--tRNA ligase CL:0000000 CELL TYPE ONTOLOGY 52-90-4 CAS 1.0 C00037 KEGG Compound C00036 KEGG Compound Glutamate decarboxylase 1 328-50-7 CAS SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O AMP BioCyc SMILES OC(=O)CCC(O)=O C00041 KEGG Compound Q5JPH6 UniProt 110467 ChemSpider 1.0 Adenosine diphosphate CHEBI:29175 ChEBI 1.0 SMILES [O-]P([O-])(=O)OP([O-])([O-])=O CARBON-DIOXIDE BioCyc L-Glutamine C00042 KEGG Compound 2.4.2.14 false 2.4.2.14 5-Phosphoribosylamine + L-Glutamic acid + Pyrophosphate ↔ L-Glutamine + Phosphoribosyl pyrophosphate + Water REVERSIBLE 1.0 C00049 KEGG Compound 3.5.1.2 false 3.5.1.2 L-Glutamine + Water → Ammonia + L-Glutamic acid LEFT_TO_RIGHT C00169 KEGG Compound 56-85-9 CAS 1.2.1.88 false 1.2.1.88 1-Pyrroline-5-carboxylic acid + NAD + 2 Water ↔ L-Glutamic acid + NADH REVERSIBLE SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 7062 ChemSpider 4.0 ADENOSINE_DIPHOSPHATE_RIBOSE BioCyc Alanine aminotransferase 1 1.0 C00051 KEGG Compound HMDB00538 HMDB 6.0 389821 ChemSpider Oxoglutaric acid 399508 ChemSpider SMILES OC(=O)CC(=O)C(O)=O Amidophosphoribosyltransferase Q06203 UniProt 7732-18-5 CAS C28H49N3O16 Chitin 683.3113 61-19-8 CAS NAD SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 123938 PubChem-compound P51649 UniProt 10.0 AMMONIA BioCyc SMILES N SMILES OC(=O)C1CCC=N1 56-86-0 CAS GMP synthase [glutamine-hydrolyzing] L-Cysteine 590-55-6 CAS Adenosine diphosphate Glutamate dehydrogenase 1, mitochondrial Arginine and Proline Metabolism SubPathway Histidine Metabolism SubPathway 14-N-ACETYL-BETA-D-GLUCOSAMINYLN1 BioCyc CHEBI:29157 ChEBI Glutathione Metabolism SubPathway 1.8.1.7 false 1.8.1.7 NADPH + Oxidized glutathione ↔ 2 Glutathione + NADP REVERSIBLE HMDB00641 HMDB BiologicalState14 C10H16N5O13P3 Adenosine triphosphate 506.99576 Q06210 UniProt CHEBI:17053 ChEBI 56-40-6 CAS XANTHOSINE-5-PHOSPHATE BioCyc C00064 KEGG Compound P24298 UniProt Pyrophosphate 2.6.1.2 false 2.6.1.2 L-Alanine + Oxoglutaric acid ↔ L-Glutamic acid + Pyruvic acid REVERSIBLE Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 SMILES CC(=O)C(O)=O Urea Cycle SubPathway 1.0 Ammonia HMDB01967 HMDB 962 PubChem-compound P00390 UniProt 1.0 C3H7NO2 L-Alanine 89.047676 5800 ChemSpider 1.0 979 ChemSpider CO2 Carbon dioxide 43.98983 636-58-8 CAS 1.0 C00080 KEGG Compound 730 ChemSpider C00085 KEGG Compound H3O4P Phosphoric acid 97.9769 BiologicalState8 SMILES N[C@@H](CCC(O)=O)C(O)=O BiologicalState3 Glutathione Probable glutamate--tRNA ligase, mitochondrial Glutamine synthetase L-Glutamine 14265-44-2 CAS Glutamine--fructose-6-phosphate aminotransferase PYRUVATE BioCyc 58-64-0 CAS 1.0 Glutaminase liver isoform, mitochondrial C04322 KEGG Compound 4-aminobutyrate aminotransferase, mitochondrial NADP SMILES O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1NC(=O)NC2=O C4H7NO4 L-Aspartic acid 133.0375 439905 PubChem-compound Succinate-semialdehyde dehydrogenase, mitochondrial 644102 PubChem-compound C3H7NO2S L-Cysteine 121.01975 444493 PubChem-compound 6083 PubChem-compound C00097 KEGG Compound 22833512 PubChem-compound ACETYL-COA BioCyc Adenosine diphosphate ribose CHEBI:18050 ChEBI H2O Water 18.010565 4-AMINO-BUTYRATE BioCyc SMILES OCC(=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O 1.0 SMILES NCC(O)=O SMILES O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O 388939 ChemSpider Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial NADH BioCyc SMILES NCCCC(O)=O NAD BioCyc N-Acetyl-D-Glucosamine 6-Phosphate 1.0 NADPH Glutamine synthetase 2.0 Glutamate dehydrogenase 1, mitochondrial 56-84-8 CAS 747 ChemSpider 102029-88-9 CAS 970 PubChem-compound L-GAMMA-GLUTAMYLCYSTEINE BioCyc 1.0 SMILES N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O 5-P-BETA-D-RIBOSYL-AMINE BioCyc 1.0 3.0 30572 ChemSpider 17215925 ChemSpider C4H4O5 Oxalacetic acid 132.00587 1.0 SMILES N[C@@H](CS)C(O)=O 4.0 Carbamoyl-phosphate synthase [ammonia], mitochondrial C5H7NO2 1-Pyrroline-5-carboxylic acid 113.047676 SMILES O H3N Ammonia 17.026548 2.6.1.16 false 2.6.1.16 Fructose 6-phosphate + L-Glutamine → Glucosamine 6-phosphate + L-Glutamic acid LEFT_TO_RIGHT 21252321 PubChem-compound C10H14N5O7P Adenosine monophosphate 347.06308 Pyrophosphate ReactionCatalysis26 ACTIVATION 119 PubChem-compound 1.2.1.24 false 1.2.1.24 NAD + Succinic acid semialdehyde + Water → Hydrogen Ion + NADH + Succinic acid LEFT_TO_RIGHT Chitin 1004 PubChem-compound 5961 PubChem-compound 1.0 1.0 P27708 UniProt Ammonia 643-13-0 CAS GMP synthase [glutamine-hydrolyzing] 1.0 6816 PubChem-compound 328-42-7 CAS Water 51 PubChem-compound CHEBI:37737 ChEBI CHEBI:15846 ChEBI P00367 UniProt Succinic acid semialdehyde ADP BioCyc 2.0 C3H4O3 Pyruvic acid 88.016045 GMP synthase [glutamine-hydrolyzing] ReactionCatalysis38 ACTIVATION ReactionCatalysis39 ACTIVATION Glycine Glutathione reductase, mitochondrial ReactionCatalysis37 ACTIVATION N-ACETYL-D-GLUCOSAMINE-6-P BioCyc 53-59-8 CAS SubPathwayInteraction855 SubPathwayReaction SubPathway855Reaction SubPathwayInteraction856 SubPathway856Reaction SubPathwayReaction 1.0 SubPathwayInteraction859 SubPathway859Reaction SubPathwayReaction Phosphoribosyl pyrophosphate SubPathwayInteraction857 SubPathway857Reaction SubPathwayReaction Glutamate decarboxylase 1 1038 PubChem-compound SubPathwayInteraction858 SubPathwayReaction SubPathway858Reaction N-acetyl-D-glucosamine kinase P48637 UniProt 274 ChemSpider Adenosine monophosphate C5H6O5 Oxoglutaric acid 146.02153 272 ChemSpider Hydrogen Ion HMDB00902 HMDB 4-aminobutyrate aminotransferase, mitochondrial CHEBI:16908 ChEBI Glucosamine 6-phosphate O4P Phosphate 94.95342 ReactionCatalysis41 ACTIVATION Glutathione synthetase 5862 PubChem-compound ReactionCatalysis43 ACTIVATION ReactionCatalysis44 ACTIVATION 1.0 tRNA(Gln) Adenosine triphosphate L-Glutaminyl-tRNA(Gln) CHEBI:15946 ChEBI C21H30N7O17P3 NADPH 745.0911 Mitochondrion C21H29N7O17P3 NADP 744.08325 ReactionCatalysis2202 ACTIVATION ReactionCatalysis2201 ACTIVATION GLY BioCyc NADPH BioCyc Reaction78 false L-Aspartic acid + Oxoglutaric acid ↔ L-Glutamic acid + Oxalacetic acid REVERSIBLE CHEBI:16977 ChEBI 2.0 CHEBI:16856 ChEBI 217 ChemSpider 58-68-4 CAS C4H9NO2 Gamma-Aminobutyric acid 103.06333 Water C5H13O14P3 Phosphoribosyl pyrophosphate 389.9518 SMILES [O-]P([O-])([O-])=O GMP BioCyc SMILES OC(=O)CCC(=O)C(O)=O 692-29-5 CAS GO:0005886 GENE ONTOLOGY CHEBI:30915 ChEBI C6H13O9P Fructose 6-phosphate 260.02972 1398-61-4 CAS 124-38-9 CAS Glutamine--tRNA ligase l-delta(1)-pyrroline_5-carboxylate BioCyc C2H5NO2 Glycine 75.03203 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 CHEBI:15652 ChEBI CHEBI:16865 ChEBI CAD protein ReactionCatalysis2 ACTIVATION Glutamate--cysteine ligase regulatory subunit 1.0 SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O P48506 UniProt 1.0 P48507 UniProt 5257127 PubChem-compound C10H17N3O6S Glutathione 307.0838 1.0 SMILES NC(=O)C1=CN(C=CC1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2O[C@@H]([C@@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O P47897 UniProt GLN BioCyc GLT BioCyc 7664-41-7 CAS Gamma-Glutamylcysteine Coenzyme A 2.0 69507 PubChem-compound 53-57-6 CAS Pyrimidine Metabolism SubPathway Purine Metabolism SubPathway Histidine Metabolism SubPathway CHEBI:15741 ChEBI Arginine and Proline Metabolism SubPathway Arginine and Proline Metabolism SubPathway 1112 PubChem-compound SMILES O=C=O SMILES C[C@H](N)C(O)=O 5950 PubChem-compound 222 PubChem-compound 2.0 1110 PubChem-compound 116 ChemSpider SMILES OP(O)(O)=O O7P2 Pyrophosphate 173.91193 C21H29N7O14P2 NADH 665.12476 1.0 L-glutamyl-tRNA(Glu) 5957 PubChem-compound 6804 PubChem-compound Glutamine synthetase C03090 KEGG Compound 463-79-6 CAS C4H6O4 Succinic acid 118.02661 CHEBI:16960 ChEBI CHEBI:15873 ChEBI 2.3.1.4 false 2.3.1.4 Acetyl-CoA + Glucosamine 6-phosphate → Coenzyme A + N-Acetyl-D-Glucosamine 6-Phosphate LEFT_TO_RIGHT HMDB01096 HMDB 2.0 440996 PubChem-compound Xanthylic acid 1.0 GO:0005739 GENE ONTOLOGY C10H15N5O10P2 Adenosine diphosphate 427.02942 L-Glutaminyl-tRNA(Gln) GO:0005737 GENE ONTOLOGY 2.0 tRNA(Gln) SMILES N[C@@H](CC(O)=O)C(O)=O 1.0 Succinic acid semialdehyde 6.0 70-18-8 CAS 1.0 SUCC-S-ALD BioCyc HMDB03362 HMDB CPD-8587 BioCyc SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O HMDB01062 HMDB 1.0 SMILES N[C@H]1[C@@H](O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O 5682 ChemSpider CHEBI:1146900 ChEBI 1.0 5255796 PubChem-compound 1.0 SMILES OC(=O)CCC=O Acetyl-CoA Alanine aminotransferase 1 1.0 C10H14N5O8P Guanosine monophosphate 363.058 CAD protein 14000-31-8 CAS CARBAMOYL-P BioCyc P30038 UniProt CO-A BioCyc CHEBI:17515 ChEBI Glutamate decarboxylase 1 5675 ChemSpider 72-89-9 CAS 1078 ChemSpider 1.0 Carbon dioxide C21H36N7O16P3S Coenzyme A 767.11523 P49915 UniProt CHEBI:1372 ChEBI SMILES NC(=O)OP(O)(O)=O 1080 ChemSpider 4.0 22639876 PubChem-compound Glucosamine 6-phosphate Cytoplasm Cell CHEBI:15784 ChEBI HMDB01049 HMDB CHEBI:15422 ChEBI SMILES OC(O)=O 6557 ChemSpider P80404 UniProt HMDB00191 HMDB SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N Oxalacetic acid 1.0 388299 ChemSpider SMILES N[C@@H](CCC(=O)N[C@@H](CS)C(O)=O)C(O)=O 127-17-3 CAS 439217 PubChem-compound Reaction494 false 2 Adenosine triphosphate + Carbonic acid + L-Glutamine + Water → 2 Adenosine diphosphate + Carbamoyl phosphate + L-Glutamic acid + Phosphoric acid LEFT_TO_RIGHT Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial C5H9NO4 L-Glutamic acid 147.05316 1.0 33032 PubChem-compound 1.0 HMDB01178 HMDB Glucosamine 6-phosphate N-acetyltransferase CHEBI:17858 ChEBI Glucosamine 6-phosphate N-acetyltransferase CHEBI:16526 ChEBI N-acetyl-D-glucosamine kinase 6545 ChemSpider Glutathione SMILES CC(=O)N[C@H]1C(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O Phosphoric acid Glutamate--cysteine ligase HMDB02142 HMDB CHEBI:16761 ChEBI Oxidized glutathione C10H13N4O9P Xanthylic acid 364.04202 CHEBI:28976 ChEBI 2.0 CHEBI:15428 ChEBI 3.0 1.0 NADH 9606 TAXONOMY ReactionCatalysis114 ACTIVATION ReactionCatalysis112 ACTIVATION Glutamate Metabolism 2-KETOGLUTARATE BioCyc 6.1.1.18 false 6.1.1.18 Adenosine triphosphate + L-Glutamine + tRNA(Gln) → Adenosine monophosphate + L-Glutaminyl-tRNA(Gln) + Pyrophosphate LEFT_TO_RIGHT 392413 ChemSpider 2.7.1.59 false 2.7.1.59 3 Adenosine diphosphate ribose + 3 N-Acetyl-D-Glucosamine 6-Phosphate → 3 Adenosine triphosphate + 3 Chitin LEFT_TO_RIGHT HMDB00051 HMDB 1.0 SMILES CC(=O)NC1[C@H](O)OC(CO)[C@@H](COC[C@@H]2OC(CO)[C@@H](COC[C@@H]3OC(CO)[C@@H](O)[C@H](O)C3NC(C)=O)[C@H](O)C2NC(C)=O)[C@@H]1O 5893 PubChem-compound HMDB02111 HMDB Q96EK6 UniProt Aspartate aminotransferase, mitochondrial 110-15-6 CAS N-acetyl-D-glucosamine kinase Phosphoric acid Amidophosphoribosyltransferase L-Alanine Oxoglutaric acid ReactionCatalysis2211 ACTIVATION CHEBI:32816 ChEBI 1.0 ReactionCatalysis2212 ACTIVATION 1.0 CHEBI:15377 ChEBI Cell Membrane 1.0 1.0 HMDB03337 HMDB 278 PubChem-compound Aspartate aminotransferase, mitochondrial CHEBI:15378 ChEBI SMILES [H+] PW000010 PathWhiz 6.3.4.16 false 6.3.4.16 2 Adenosine triphosphate + Ammonia + Carbon dioxide + Water → 2 Adenosine diphosphate + Carbamoyl phosphate + Phosphoric acid LEFT_TO_RIGHT SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O 5886 PubChem-compound P31327 UniProt 1.0 1.0 Phosphate HMDB01397 HMDB C15H23N5O14P2 Adenosine diphosphate ribose 559.07166 CHEBI:17672 ChEBI ReactionCatalysis2225 ACTIVATION SMP00072 SMPDB 1.0 280 PubChem-compound CHEBI:30744 ChEBI Glutathione reductase, mitochondrial ReactionCatalysis2222 ACTIVATION 111188 ChemSpider ReactionCatalysis2221 ACTIVATION 2.0 ReactionCatalysis2224 ACTIVATION ReactionCatalysis2223 ACTIVATION HMDB01487 HMDB Glutathione synthetase ReactionCatalysis133 ACTIVATION C00655 KEGG Compound HMDB01128 HMDB 56-12-2 CAS 27025-41-8 CAS PW000004 PathWhiz PW000003 PathWhiz ReactionCatalysis372 ACTIVATION Q9UJ70 UniProt SMILES N[C@@H](CCC(N)=O)C(O)=O 1.0 1196 PubChem-compound Gamma-Aminobutyric acid SubPathwayInput PRPP BioCyc 1.0 Glucosamine 6-phosphate N-acetyltransferase 2.0 Succinate-semialdehyde dehydrogenase, mitochondrial 192 PubChem-compound tRNA(Glu) L-glutamyl-tRNA(Glu) HMDB00045 HMDB 1060 PubChem-compound C00669 KEGG Compound 1061 PubChem-compound Glutaminase liver isoform, mitochondrial 523-98-8 CAS HMDB01259 HMDB HMDB00280 HMDB HMDB00161 HMDB CHEBI:15351 ChEBI 1-Pyrroline-5-carboxylic acid SubPathwayOutput C00301 KEGG Compound HMDB01254 HMDB SMILES NC(CCC(=O)NC(CSSCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O P00505 UniProt SMILES N[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O 187 ChemSpider 2906-39-0 CAS 1.0 20762-30-5 CAS 6.3.2.3 false 6.3.2.3 Adenosine triphosphate + Gamma-Glutamylcysteine + Glycine → Adenosine diphosphate + Glutathione + Phosphate LEFT_TO_RIGHT 85-61-0 CAS 1.0 4.1.1.15 false 4.1.1.15 L-Glutamic acid → Carbon dioxide + Gamma-Aminobutyric acid LEFT_TO_RIGHT 6.1.1.17 false 6.1.1.17 Adenosine triphosphate + Oxoglutaric acid + tRNA(Glu) → Adenosine monophosphate + L-glutamyl-tRNA(Glu) + Pyrophosphate LEFT_TO_RIGHT 6.3.2.2 false 6.3.2.2 Adenosine triphosphate + L-Cysteine + L-Glutamic acid → Adenosine diphosphate ribose + Gamma-Glutamylcysteine + Phosphate LEFT_TO_RIGHT 6.3.5.2 false 6.3.5.2 Adenosine triphosphate + L-Glutamine + Water + Xanthylic acid → Adenosine monophosphate + Guanosine monophosphate + L-Glutamic acid + Pyrophosphate LEFT_TO_RIGHT Glutamine synthetase Glutaminase liver isoform, mitochondrial Glutamine-- fructose-6- phosphate aminotransferase [isomerizing] 1