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Feline leukemia virus subgroup C receptor- related protein 2 5- aminolevulinate synthase, nonspecific, mitochondrial Delta- aminolevulinic acid dehydratase Porphobilinogen deaminase Uroporphyrinogen- III synthase Uroporphyrinogen decarboxylase Uroporphyrinogen decarboxylase Coproporphyrinogen- III oxidase, mitochondrial Ferritin, mitochondrial Ferrochelatase, mitochondrial Protoheme IX farnesyltransferase, mitochondrial Cytochrome c oxidase assembly protein COX15 homolog Biliverdin reductase A UDP- glucuronosyltransferase 2B11 Beta- glucuronidase Protoporphyrinogen oxidase Heme oxygenase 1 Glycine Accumulation Coproporphyrinogen III Accumulation Coproporphyrinogen III Accumulation Protoporphyrin IX Accumulation Protoporphyrin IX Heme Heme Succinyl-CoA Accumulation 5-Aminolevulinic acid CO2 Accumulation Porphobilinogen H2O H2O Hydroxymethylbilane NH3 Uroporphyrinogen III H2O Accumulation Uroporphyrin III Uroporphyrinogen I Coproporphyrinogen I CO2 Accumulation Coproporphyrin I Uroporphyrin I CO2 Accumulation Coproporphyrin III O2 H+ Accumulation Protoporphyrinogen IX CO2 H2O Fe2+ H+ O2 Fe3+ H2O H+ Farnesyl pyrophosphate Heme O Heme A Biliverdin NAD Bilirubin NADH Uridine diphosphate glucuronic acid Bilirubin diglucuronide Uridine 5'-diphosphate H2O Urobilinogen O2 H2O2 O2 Fe2+ Carbon monoxide H2O Pyridoxal 5'-phosphate Zinc Zinc Alcohol AH2 A Glycine and Serine Metabolism FAD 2Fe-2S Intracellular Space Mitochondria Outer mitochondrial membrane Inner mitochondrial membrane Microsome Microsome Lysosome
Mitochondria FLVCR2 ALAS1 ALAD HMBS UROS UROD UROD CPOX FTMT FECH COX10 COX15 BLVRA UGT2B11 GUSB PPOX HMOX1 Glycine Accumulation Coproporphyrinogen III Accumulation Coproporphyrinogen III Accumulation Protoporphyrin IX Accumulation Protoporphyrin IX Heme Heme Succinyl-CoA Accumulation 5- Aminolevulinic acid Carbon dioxide Accumulation Porphobilinogen Water Water Hydroxymethylbilane Ammonia Uroporphyrinogen III Water Accumulation Uroporphyrin III Uroporphyrinogen I Coproporphyrinogen I Carbon dioxide Accumulation Coproporphyrin I Uroporphyrin I Carbon dioxide Accumulation Coproporphyrin III Oxygen Hydrogen Accumulation Protoporphyrinogen IX Carbon dioxide Water Fe2+ Hydrogen Oxygen Fe3+ Water Hydrogen Farnesyl pyrophosphate Heme O Heme A Biliverdin NAD Bilirubin NADH Uridine diphosphate glucuronic acid Bilirubin diglucuronide Uridine 5'-diphosphate Water Urobilinogen Oxygen Hydrogen peroxide Oxygen Fe2+ Carbon monoxide Water Alcohol AH2 A Glycine and Serine Metabolism
FLVCR2 ALAS1 ALAD HMBS UROS UROD UROD CPOX FTMT FECH COX10 COX15 BLVRA UGT2B11 GUSB PPOX HMOX1 Gly Accumulation Coprgn3 Accumulation Coprgn3 Accumulation PrtopIX Accumulation PrtopIX Heme Heme Suc-CoA Accumulation 5-Amnva CO2 Accumulation PBG H2O H2O HMBilan NH3 Urppr3 H2O Accumulation Urop3 Uropg1 CPPgen CO2 Accumulation CopropI Urop1 CO2 Accumulation CoprIII O2 H+ Accumulation Protop9 CO2 H2O Fe2+ H+ O2 Fe3+ H2O H+ FarPP Heme O Heme A Bilvdn NAD BilRubn NADH UDPGlcA BRubnDG UDP H2O Urbilgn O2 H2O2 O2 Fe2+ CO H2O Pyr-5'P Zinc Zinc Alcohol AH2 A PW000157 FAD 2Fe2S Intracellular Space Mitochondria Outer mitochondrial membrane Inner mitochondrial membrane Microsome Microsome Lysosome
Mitochondria FLVCR2 ALAS1 ALAD HMBS UROS UROD UROD CPOX FTMT FECH COX10 COX15 BLVRA UGT2B11 GUSB PPOX HMOX1 Gly Accumulation Coprgn3 Accumulation Coprgn3 Accumulation PrtopIX Accumulation PrtopIX Heme Heme Suc-CoA Accumulation 5-Amnva CO2 Accumulation PBG H2O H2O HMBilan NH3 Urppr3 H2O Accumulation Urop3 Uropg1 CPPgen CO2 Accumulation CopropI Urop1 CO2 Accumulation CoprIII O2 H2 Accumulation Protop9 CO2 H2O Fe2+ H2 O2 Fe3+ H2O H2 FarPP Heme O Heme A Bilvdn NAD BilRubn NADH UDPGlcA BRubnDG UDP H2O Urbilgn O2 H2O2 O2 Fe2+ CO H2O Alcohol AH2 A PW000157