Quantitative metabolomics services for biomarker discovery and validation.
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Glycerol-3- phosphate dehydrogenase [NAD(+)], cytoplasmic glycerol-3- phosphate acyltransferase 1-acyl-sn- glycerol-3- phosphate acyltransferase phosphatidate phosphatase diacylglycerol O- acyltransferase Dihydroxyacetone phosphate NADH H + NAD Glycerol 3-phosphate Erucoyl-CoA CoA LPA(22:1(13Z)/0:0) LPA(22:1(13Z)/0:0) (10Z,13Z)- Nonadecadienoyl- CoA CoA PA(22:1(13Z)/19:2(10Z,13Z)) H 2 O DG(22:1(13Z)/19:2(10Z,13Z)/0:0) P i Docosahexaenoyl- CoA TG(22:1(13Z)/19:2(10Z,13Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) CoA Glycolysis Mitochondria Outer Membrane Endoplasmic Reticulum Membrane Cytosol
Mitochondria Endoplasmic Reticulum GPD1 GPAM AGPAT1 LPIN1 DGAT1 Dihydroxyacetone phosphate NADH Hydrogen Ion NAD Glycerol 3-phosphate Erucoyl-CoA Coenzyme A LPA(22:1(13Z)/0:0) LPA(22:1(13Z)/0:0) (10Z,13Z)- Nonadecadienoyl- CoA Coenzyme A PA(22:1(13Z)/19:2(10Z,13Z)) Water DG(22:1(13Z)/19:2(10Z,13Z)/0:0) Phosphate Docosahexaenoyl- CoA TG(22:1(13Z)/19:2(10Z,13Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) Coenzyme A Glycolysis