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Ca+ Na+ Ca+ Ca+ Na+ K+ K+ Sodium- dependent serotonin transporter Amine oxidase [flavin- containing] A Amine oxidase [flavin- containing] B Amine oxidase [flavin- containing] A Amine oxidase [flavin- containing] B Amine oxidase [flavin- containing] A Amine oxidase [flavin- containing] B Aldehyde oxidase Cytochrome P450 2D6 Cytochrome P450 3A7 Cytochrome P450 2C19 Cytochrome P450 2D6 Cytochrome P450 2D6 Alpha-1A adrenergic receptor 5- hydroxytryptamine receptor 1A D(1A) dopamine receptor Beta-endorphin Mu-type opioid receptor Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit alpha-4 Voltage- dependent P/Q-type calcium channel subunit alpha-1A Voltage- dependent L-type calcium channel subunit beta-1 Voltage- dependent calcium channel subunit alpha-2/delta-2 Potassium voltage-gated channel subfamily D member 2 Kv channel- interacting protein 2 Beta-endorphin Glutamate [NMDA] receptor subunit zeta-1 Glutamate [NMDA] receptor subunit epsilon-1 Glutamate [NMDA] receptor subunit 3A Sodium- dependent noradrenaline transporter Sodium- dependent serotonin transporter Sodium- dependent dopamine transporter Pro- opiomelanocortin Neuroendocrine convertase 2 Sodium/potassium- transporting ATPase subunit alpha-1 Citalopram Citalopram H2O O2 Citalopram aldehyde Dimethylamine H2O2 N-Desmethylcitalopram H2O O2 Methylammonium H2O2 Didemethylcitalopram H2O O2 NH3 H2O2 H2O O2 Citalopram propionic acid H2O2 O2 NADH H2O Formaldehyde NAD O2 NADH H2O Formaldehyde NAD O2 H2O Citalopram N-oxide H2O2 FAD FAD FAD FAD FAD FAD FAD Molybdopterin 2Fe-2S Heme Heme Heme Heme Heme Norepinephrine Serotonin Dopamine Ca+ Na+ K+ Ca+ Ca+ Norepinephrine Serotonin Na+ Na+ Na+ Na+ Dopamine Na+ Na+ ATP H2O Na+ K+ ADP Pi Na+ K+ Sodium channel protein type 10 subunit alpha Neuronal acetylcholine receptor subunit alpha-4 Sodium channel subunit beta-1 Sodium/potassium- transporting ATPase subunit alpha-3 Sodium/potassium- transporting ATPase subunit beta-2 Sodium/potassium- transporting ATPase subunit alpha-2 Sodium/potassium- transporting ATPase subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-1 Sodium/potassium- transporting ATPase subunit gamma Neuronal acetylcholine receptor subunit alpha-4 Sodium/potassium- transporting ATPase subunit beta-3 ATPase, (Na+)/K+ transporting, beta 4 polypeptide Axon Terminal Mitochondrion outer membrane Synaptic Vesicle Presynaptic Neuron Postsynaptic Neuron Synaptic Cleft Neuron Neuron Axon Action Potential Membrane Potential (mV) Resting Potential -70 Time +40 0 Depolarization Peak Action Potential Repolarization Hyperpolarization
Chloroplast Mitochondria Vacuole Calcium Sodium Calcium Calcium Sodium Potassium Potassium SLC6A4 MAOA MAOB MAOA MAOB MAOA MAOB AOX1 CYP2D6 CYP3A7 CYP2C19 CYP2D6 CYP2D6 ADRA1A HTR1A DRD1 Unknown OPRM1 Unknown Unknown Unknown Unknown CACNA1A CACNB1 CACNA2D2 KCND2 KCNIP2 Unknown GRIN1 GRIN2A GRIN3A SLC6A2 SLC6A4 SLC6A3 Unknown Unknown ATP1A1 Citalopram Citalopram Water Oxygen Citalopram aldehyde Dimethylamine Hydrogen peroxide N- Desmethylcitalopram Water Oxygen Methylammonium Hydrogen peroxide Didemethylcitalopram Water Oxygen Ammonia Hydrogen peroxide Water Oxygen Citalopram propionic acid Hydrogen peroxide Oxygen NADH Water Formaldehyde NAD Oxygen NADH Water Formaldehyde NAD Oxygen Water Citalopram N-oxide Hydrogen peroxide Norepinephrine Serotonin Dopamine Calcium Sodium Potassium Calcium Calcium Norepinephrine Serotonin Sodium Sodium Sodium Sodium Dopamine Sodium Sodium Adenosine triphosphate Water Sodium Potassium Adenosine diphosphate Phosphate Sodium Potassium SCN10A Unknown SCN1B ATP1A3 ATP1B2 ATP1A2 ATP1A4 ATP1B1 FXYD2 Unknown ATP1B3 Unknown Created with Snap
Ca+ Na+ Ca+ Ca+ Na+ K+ K+ SLC6A4 MAOA MAOB MAOA MAOB MAOA MAOB AOX1 CYP2D6 CYP3A7 CYP2C19 CYP2D6 CYP2D6 ADRA1A HTR1A DRD1 OPRM1 CACNA1A CACNB1 CACNA2D2 KCND2 KCNIP2 GRIN1 GRIN2A GRIN3A SLC6A2 SLC6A4 SLC6A3 ATP1A1 Citalpm Citalpm H2O O2 CitAl DMAmine H2O2 NDesmp H2O O2 Methamm H2O2 Didemet H2O O2 NH3 H2O2 H2O O2 CPA H2O2 O2 NADH H2O Formol NAD O2 NADH H2O Formol NAD O2 H2O CitpN-O H2O2 FAD FAD FAD FAD FAD FAD FAD mlyBdpn 2Fe2S Heme Heme Heme Heme Heme Norpp 5-HT LDP Ca+ Na+ K+ Ca+ Ca+ Norpp 5-HT Na+ Na+ Na+ Na+ LDP Na+ Na+ ATP H2O Na+ K+ ADP Pi Na+ K+ SCN10A SCN1B ATP1A3 ATP1B2 ATP1A2 ATP1A4 ATP1B1 FXYD2 ATP1B3 Axon Terminal Mitochondrion outer membrane Synaptic Vesicle Presynaptic Neuron Postsynaptic Neuron Synaptic Cleft Neuron Neuron Axon Action Potential Membrane Potential (mV) Resting Potential -70 Time +40 0 Depolarization Peak Action Potential Repolarization Hyperpolarization
Chloroplast Mitochondria Vacuole Ca2+ Na+ Ca2+ Ca2+ Na+ K+ K+ SLC6A4 MAOA MAOB MAOA MAOB MAOA MAOB AOX1 CYP2D6 CYP3A7 CYP2C19 CYP2D6 CYP2D6 ADRA1A HTR1A DRD1 OPRM1 CACNA1A CACNB1 CACNA2D2 KCND2 KCNIP2 GRIN1 GRIN2A GRIN3A SLC6A2 SLC6A4 SLC6A3 ATP1A1 Citalpm Citalpm H2O O2 CitAl DMAmine H2O2 NDesmp H2O O2 Methamm H2O2 Didemet H2O O2 NH3 H2O2 H2O O2 CPA H2O2 O2 NADH H2O Formol NAD O2 NADH H2O Formol NAD O2 H2O CitpN-O H2O2 Norpp 5-HT LDP Ca2+ Na+ K+ Ca2+ Ca2+ Norpp 5-HT Na+ Na+ Na+ Na+ LDP Na+ Na+ ATP H2O Na+ K+ ADP Pi Na+ K+ SCN10A SCN1B ATP1A3 ATP1B2 ATP1A2 ATP1A4 ATP1B1 FXYD2 ATP1B3 Created with Snap