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Beta-1,4 N- acetylgalactosaminyltransferase 1 Beta-1,3- galactosyltransferase 4 Lactosylceramide alpha-2,3- sialyltransferase Alpha-N- acetylneuraminide alpha-2,8- sialyltransferase Beta-1,4 N- acetylgalactosaminyltransferase 1 Beta-1,3- galactosyltransferase 4 CMP-N- acetylneuraminate- beta- galactosamide- alpha-2,3- sialyltransferase 1 Alpha-2,8- sialyltransferase 8E Beta-1,4 N- acetylgalactosaminyltransferase 1 Beta-1,3- galactosyltransferase 4 CMP-N- acetylneuraminate- beta- galactosamide- alpha-2,3- sialyltransferase 1 Alpha-2,8- sialyltransferase 8E Alpha-2,8- sialyltransferase 8E Beta-1,4 N- acetylgalactosaminyltransferase 1 Beta-1,3- galactosyltransferase 4 Alpha-N- acetylgalactosaminide alpha-2,6- sialyltransferase 6 Alpha-N- acetylgalactosaminide alpha-2,6- sialyltransferase 6 Beta- galactosidase Beta- hexosaminidase subunit alpha Beta- hexosaminidase subunit beta CMP-N- acetylneuraminate- beta- galactosamide- alpha-2,3- sialyltransferase 1 Alpha-2,8- sialyltransferase 8E Alpha-N- acetyl- neuraminyl- 2,3-beta- galactosyl- 1,3-N-acetyl- galactosaminide alpha-2,6- sialyltransferase Lactosylceramide (d18:1/25:0) Ganglioside GM1 (18:1/20:0) Ganglioside GM1 (18:1/20:0) Ganglioside GM2 (d18:1/24:0) Ganglioside GM2 (d18:1/24:0) Uridine diphosphate- N- acetylgalactosamine Uridine 5'-diphosphate Ganglioside GA2 (d18:1/9Z-18:1) Uridine diphosphategalactose Uridine 5'-diphosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Ganglioside GM3 (d18:1/24:1(15Z)) Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Ganglioside GD3 (d18:1/24:1(15Z)) Uridine diphosphate- N- acetylgalactosamine Uridine 5'-diphosphate Uridine diphosphategalactose Uridine 5'-diphosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Uridine diphosphate- N- acetylgalactosamine Uridine 5'-diphosphate Uridine diphosphategalactose Uridine 5'-diphosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Uridine diphosphate- N- acetylgalactosamine Uridine 5'-diphosphate Uridine diphosphategalactose Uridine 5'-diphosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate H2O D-Galactose H2O Ganglioside GM3 (d18:1/24:1(15Z)) N- Acetylgalactosamine Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate GA1 GD1a GT1a GD2 GD1b GT1b GQ1 GT3 GT2 GT1c GQ1bα GT1aα GM1b GD1c GD1α Sphingolipid Metabolism Golgi Apparatus Membrane Lysosome
Golgi Apparatus Lysosome B4GALNT1 B3GALT4 ST3GAL5 ST8SIA1 B4GALNT1 B3GALT4 ST3GAL1 ST8SIA5 B4GALNT1 B3GALT4 ST3GAL1 ST8SIA5 ST8SIA5 B4GALNT1 B3GALT4 ST6GALNAC6 ST6GALNAC6 GLB1 HEXA HEXB ST3GAL1 ST8SIA5 ST6GALNAC4 Lactosylceramide (d18:1/25:0) Ganglioside GM1 (18:1/20:0) Ganglioside GM1 (18:1/20:0) Ganglioside GM2 (d18:1/24:0) Ganglioside GM2 (d18:1/24:0) Uridine diphosphate- N- acetylgalactosamine Uridine 5'-diphosphate Ganglioside GA2 (d18:1/9Z-18:1) Uridine diphosphategalactose Uridine 5'-diphosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Ganglioside GM3 (d18:1/24:1(15Z)) Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Ganglioside GD3 (d18:1/24:1(15Z)) Uridine diphosphate- N- acetylgalactosamine Uridine 5'-diphosphate Uridine diphosphategalactose Uridine 5'-diphosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Uridine diphosphate- N- acetylgalactosamine Uridine 5'-diphosphate Uridine diphosphategalactose Uridine 5'-diphosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Uridine diphosphate- N- acetylgalactosamine Uridine 5'-diphosphate Uridine diphosphategalactose Uridine 5'-diphosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Water D-Galactose Water Ganglioside GM3 (d18:1/24:1(15Z)) N- Acetylgalactosamine Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate Cytidine monophosphate N- acetylneuraminic acid Cytidine monophosphate GA1 GD1a GT1a GD2 GD1b GT1b GQ1 GT3 GT2 GT1c GQ1bα GT1aα GM1b GD1c GD1α Sphingolipid Metabolism
B4GALNT1 B3GALT4 ST3GAL5 ST8SIA1 B4GALNT1 B3GALT4 ST3GAL1 ST8SIA5 B4GALNT1 B3GALT4 ST3GAL1 ST8SIA5 ST8SIA5 B4GALNT1 B3GALT4 ST6GALNAC6 ST6GALNAC6 GLB1 HEXA HEXB ST3GAL1 ST8SIA5 ST6GALNAC4 Cdh Gm1 Gm1 Gm2 Gm2 UNA UDP Ga2 UDPPG UDP CMPNAc CMP Gm3 CMPNAc CMP Gd3 UNA UDP UDPPG UDP CMPNAc CMP CMPNAc CMP UNA UDP UDPPG UDP CMPNAc CMP CMPNAc CMP CMPNAc CMP UNA UDP UDPPG UDP CMPNAc CMP CMPNAc CMP H2O D-Gal H2O Gm3 Tn CMPNAc CMP CMPNAc CMP CMPNAc CMP GA1 GD1a GT1a GD2 GD1b GT1b GQ1 GT3 GT2 GT1c GQ1bα GT1aα GM1b GD1c GD1α PW000148 Golgi Apparatus Membrane Lysosome
Golgi Apparatus Lysosome B4GALNT1 B3GALT4 ST3GAL5 ST8SIA1 B4GALNT1 B3GALT4 ST3GAL1 ST8SIA5 B4GALNT1 B3GALT4 ST3GAL1 ST8SIA5 ST8SIA5 B4GALNT1 B3GALT4 ST6GALNAC6 ST6GALNAC6 GLB1 HEXA HEXB ST3GAL1 ST8SIA5 ST6GALNAC4 Cdh Gm1 Gm1 Gm2 Gm2 UNA UDP Ga2 UDPPG UDP CMPNAc CMP Gm3 CMPNAc CMP Gd3 UNA UDP UDPPG UDP CMPNAc CMP CMPNAc CMP UNA UDP UDPPG UDP CMPNAc CMP CMPNAc CMP CMPNAc CMP UNA UDP UDPPG UDP CMPNAc CMP CMPNAc CMP H2O D-Gal H2O Gm3 Tn CMPNAc CMP CMPNAc CMP CMPNAc CMP GA1 GD1a GT1a GD2 GD1b GT1b GQ1 GT3 GT2 GT1c GQ1bα GT1aα GM1b GD1c GD1α PW000148