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Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 2 Mitochondrial pyruvate carrier 1 Mitochondrial pyruvate carrier 1 Glucose-6- phosphate translocase Glucose-6- phosphatase Glucose-6- phosphatase Phosphoglucomutase- 1 Glucose-6- phosphate isomerase Hexokinase-2 Aldose 1-epimerase Hexokinase-2 Glucose-6- phosphate isomerase Fructose-1,6- bisphosphatase 1 Fructose- bisphosphate aldolase A Triosephosphate isomerase Glyceraldehyde- 3-phosphate dehydrogenase Pantothenate kinase 1 Phosphoglycerate mutase 2 Alpha-enolase Bisphosphoglycerate mutase Bisphosphoglycerate mutase Phosphoglycerate mutase 1 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Malate dehydrogenase, mitochondrial Malate dehydrogenase, mitochondrial Pyruvate carboxylase, mitochondrial Phosphoenolpyruvate carboxykinase, cytosolic [GTP] L-lactate dehydrogenase A-like 6A Pyruvate carboxylase, mitochondrial D-Glucose Glucose 1-phosphate D-Glyceraldehyde 3-phosphate Fructose 6-phosphate Phosphoenolpyruvic acid Pyruvic acid Accumulation L-Lactic acid 3-Phosphoglyceric acid Pyruvic acid D-Glucose D-Glucose Pi Pi Oxoglutaric acid Oxoglutaric acid Malic acid Malic acid Phosphoenolpyruvic acid Pyruvic acid Pyruvic acid Glucose 6-phosphate Glucose 6-phosphate H2O H2O Pi α-D-Glucose ATP ADP β-D-Glucose ATP ADP β-D-Glucose 6-phosphate Fructose 1,6-bisphosphate H2O Pi Dihydroxyacetone phosphate NAD Pi Glyceric acid 1,3-biphosphate NADH ATP ADP 2-Phospho-D-glyceric acid H2O 2,3-Diphosphoglyceric acid H2O Pi H2O Pi GTP Oxalacetic acid GDP CO2 NAD NADH H+ NAD Oxalacetic acid NADH H+ ATP HCO3- ADP Pi GTP Oxalacetic acid GDP CO2 NAD NADH H+ ATP HCO3- ADP Pi Biotin Manganese Biotin Manganese Galactose Metabolism Nucleotide Sugars Metabolism Starch and Sucrose Metabolism Pentose Phosphate Pathway Fructose and Mannose Degradation Galactose Metabolism Thiamine Metabolism Phenylalanine and Tyrosine Metabolism Pyruvate Metabolism Pantothenate and CoA Biosynthesis Aspartate Metabolism Tyrosine Metabolism Propanoate Metabolism Glycerolipid Metabolism Alanine Metabolism Pyruvate Metabolism Mitochondrial 2- oxoglutarate/malate carrier protein Magnesium Magnesium Magnesium Manganese Manganese Capillary Bed Mitochondria Endoplasmic Reticulum Intracellular Space Extracellular Space Cytosol
Endoplasmic Reticulum Mitochondria SLC2A2 SLC2A2 MPC1 MPC1 SLC37A4 G6PC G6PC PGM1 GPI HK2 GALM HK2 GPI FBP1 ALDOA TPI1 GAPDH PANK1 PGAM2 ENO1 BPGM BPGM PGAM1 PCK1 MDH2 MDH2 PC PCK1 LDHAL6A PC D-Glucose Glucose 1-phosphate D- Glyceraldehyde 3-phosphate Fructose 6-phosphate Phosphoenolpyruvic acid Pyruvic acid Accumulation L-Lactic acid 3- Phosphoglyceric acid Pyruvic acid D-Glucose D-Glucose Phosphate Phosphate Oxoglutaric acid Oxoglutaric acid Malic acid Malic acid Phosphoenolpyruvic acid Pyruvic acid Pyruvic acid Glucose 6-phosphate Glucose 6-phosphate Water Water Phosphate α-D-Glucose Adenosine triphosphate Adenosine diphosphate β-D-Glucose Adenosine triphosphate Adenosine diphosphate β-D-Glucose 6-phosphate Fructose 1,6- bisphosphate Water Phosphate Dihydroxyacetone phosphate NAD Phosphoric acid Glyceric acid 1,3-biphosphate NADH Adenosine triphosphate Adenosine diphosphate 2-Phospho-D- glyceric acid Water 2,3- Diphosphoglyceric acid Water Phosphate Water Phosphate Guanosine triphosphate Oxalacetic acid Guanosine diphosphate Carbon dioxide NAD NADH Hydrogen Ion NAD Oxalacetic acid NADH Hydrogen Ion Adenosine triphosphate Hydrogen carbonate Adenosine diphosphate Phosphate Guanosine triphosphate Oxalacetic acid Guanosine diphosphate Carbon dioxide NAD NADH Hydrogen Ion Adenosine triphosphate Hydrogen carbonate Adenosine diphosphate Phosphate Galactose Metabolism Nucleotide Sugars Metabolism Starch and Sucrose Metabolism Pentose Phosphate Pathway Fructose and Mannose Degradation Galactose Metabolism Thiamine Metabolism Phenylalanine and Tyrosine Metabolism Pyruvate Metabolism Pantothenate and CoA Biosynthesis Aspartate Metabolism Tyrosine Metabolism Propanoate Metabolism Glycerolipid Metabolism Alanine Metabolism Pyruvate Metabolism SLC25A11
SLC2A2 SLC2A2 MPC1 MPC1 SLC37A4 G6PC G6PC PGM1 GPI HK2 GALM HK2 GPI FBP1 ALDOA TPI1 GAPDH PANK1 PGAM2 ENO1 BPGM BPGM PGAM1 PCK1 MDH2 MDH2 PC PCK1 LDHAL6A PC D-Glc Gluc1P Glyc3P Fru6P Pep Pyr Accumulation Lactate G3P Pyr D-Glc D-Glc Pi Pi AKG AKG Malate Malate Pep Pyr Pyr Gluc-6P Gluc-6P H2O H2O Pi a-D-Glc ATP ADP Glu ATP ADP BDGlu6P Fru1,6P H2O Pi Dhapp NAD Pi GlyABp NADH ATP ADP 2PDG H2O 23-DpGA H2O Pi H2O Pi GTP Oaa GDP CO2 NAD NADH H+ NAD Oaa NADH H+ ATP HCO3- ADP Pi GTP Oaa GDP CO2 NAD NADH H+ ATP HCO3- ADP Pi Biotin Mn2+ Biotin Mn2+ PW000159 PW000031 PW000150 PW000055 PW000025 PW000159 PW000036 PW000042 PW000054 PW000032 PW000002 PW000142 PW000149 PW000144 PW000001 PW000054 SLC25A11 Mg2+ Mg2+ Mg2+ Mn2+ Mn2+ Capillary Bed Mitochondria Endoplasmic Reticulum Intracellular Space Extracellular Space Cytosol
Endoplasmic Reticulum Mitochondria SLC2A2 SLC2A2 MPC1 MPC1 SLC37A4 G6PC G6PC PGM1 GPI HK2 GALM HK2 GPI FBP1 ALDOA TPI1 GAPDH PANK1 PGAM2 ENO1 BPGM BPGM PGAM1 PCK1 MDH2 MDH2 PC PCK1 LDHAL6A PC D-Glc Gluc1P Glyc3P Fru6P Pep Pyr Accumulation Lactate G3P Pyr D-Glc D-Glc Pi Pi AKG AKG Malate Malate Pep Pyr Pyr Gluc-6P Gluc-6P H2O H2O Pi a-D-Glc ATP ADP Glu ATP ADP BDGlu6P Fru1,6P H2O Pi Dhapp NAD PhosfrA GlyABp NADH ATP ADP 2PDG H2O 23-DpGA H2O Pi H2O Pi GTP Oaa GDP CO2 NAD NADH H+ NAD Oaa NADH H+ ATP HCO3 ADP Pi GTP Oaa GDP CO2 NAD NADH H+ ATP HCO3 ADP Pi PW000159 PW000031 PW000150 PW000055 PW000025 PW000159 PW000036 PW000042 PW000054 PW000032 PW000002 PW000142 PW000149 PW000144 PW000001 PW000054 SLC25A11