Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.

Loading Pathway...

true true true Adenylate cyclase type 10 true Adenylate cyclase type 10 cAMP-dependent protein kinase catalytic subunit beta CPD-8587 BioCyc G protein-coupled receptor Protein kinase A catalytic subunit C00035 KEGG Compound Guanine nucleotide-binding protein alpha-beta-gamma direct_interaction 1.0 1.0 Q5JWF2 UniProt HMDB0000250 HMDB SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS Guanine nucleotide-binding protein G(T) subunit gamma-T1 Protein kinase A regulatory subunit Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Interaction467 Gαs activates Guanine nucleotide-binding protein alpha-beta-gamma HMDB0000538 HMDB C00044 KEGG Compound Interaction466 Guanine nucleotide-binding protein alpha-beta-gamma activates Guanine nucleotide-binding protein gamma-beta 1.0 ATP BioCyc P63092 UniProt Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas ReactionCatalysis101096 ACTIVATION 559142 ChemSpider Cytoplasm 1.0 C10H12N5O6P cAMP 329.05252 cAMP-dependent protein kinase catalytic subunit beta CHEBI:15422 ChEBI 1.0 cAMP-dependent protein kinase type II-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit Homo sapiens 5742 ChemSpider cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-beta regulatory subunit 1.0 C00575 KEGG Compound Guanosine diphosphate 1.0 1.0 cAMP-dependent protein kinase type I-alpha regulatory subunit Guanosine triphosphate Guanine nucleotide-binding protein G(T) subunit gamma-T1 SMP0063764 SMPDB 1.0 C10H16N5O13P3 Adenosine triphosphate 506.99576 Q96PN6 UniProt O4P Phosphate 94.95342 G protein-coupled receptor 8977 PubChem-compound 5851 ChemSpider 6830 PubChem-compound cAMP-dependent protein kinase type II-alpha regulatory subunit C10H15N5O11P2 Guanosine diphosphate 443.02432 Pyrophosphate SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O PPI BioCyc 1.0 true 9606 TAXONOMY 4.0 1.0 Activation of cAMP-dependent protein kinase, PKA C10H16N5O14P3 Guanosine triphosphate 522.99066 P62873 UniProt cAMP-dependent protein kinase type I-alpha regulatory subunit 8630 ChemSpider cAMP-dependent protein kinase type II-beta regulatory subunit HMDB0000058 HMDB SMILES [O-]P([O-])([O-])=O 1.0 P13861 UniProt SubPathwayInteraction57765 SubPathway57765Reaction SubPathwayReaction cAMP-dependent protein kinase catalytic subunit alpha 1.0 1.0 true 1.0 C00009 KEGG Compound 2.0 P31321 UniProt P10644 UniProt Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 14265-44-2 CAS 1.0 1.0 PKA Regulated Pathways SubPathway 6569 ChemSpider P31323 UniProt HMDB0001429 HMDB 2.0 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O P22694 UniProt CHEBI:18361 ChEBI CHEBI:17552 ChEBI SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 P63211 UniProt GTP BioCyc CHEBI:18367 ChEBI 1032 ChemSpider Phosphate 1.0 C00002 KEGG Compound P22612 UniProt GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE BioCyc cAMP-dependent protein kinase type I-beta regulatory subunit HMDB0001273 HMDB true Protein kinase A 644102 PubChem-compound CHEBI:17489 ChEBI 1.0 CAMP BioCyc 1.0 Adenosine triphosphate SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 cAMP-dependent protein kinase catalytic subunit gamma C00013 KEGG Compound HMDB0001201 HMDB Guanine nucleotide-binding protein gamma-beta O7P2 Pyrophosphate 173.91193 5957 PubChem-compound 1.0 86-01-1 CAS 1061 PubChem-compound 6076 PubChem-compound CHEBI:15996 ChEBI 56-65-5 CAS true cAMP-dependent protein kinase catalytic subunit alpha PW064756 PathWhiz Reaction110890 false G protein-coupled receptor + Guanine nucleotide-binding protein alpha-beta-gamma + Guanosine diphosphate + Guanosine triphosphate → Adenylate Cyclase + Guanosine diphosphate + Guanosine triphosphate + Gαs LEFT_TO_RIGHT GO:0005737 GENE ONTOLOGY P17612 UniProt 146-91-8 CAS 60-92-4 CAS Reaction110892 false Guanosine triphosphate + Gαs → Guanosine diphosphate + Gαs + Phosphate LEFT_TO_RIGHT Reaction110893 false Protein kinase A + 4 cAMP ↔ 2 Protein kinase A catalytic subunit + 2 Protein kinase A regulatory subunit REVERSIBLE Reaction110775 false Adenosine triphosphate → Pyrophosphate + cAMP LEFT_TO_RIGHT cAMP GNAS GNGT1 GNB1 GNGT1 GNB1 GNAS GNAS Adenylate Cyclase Protein kinase A Protein kinase A Protein kinase A Protein kinase A Protein kinase A regulatory subunit Protein kinase A regulatory subunit Protein kinase A catalytic subunit Protein kinase A catalytic subunit GDP GTP GTP GDP P i GDP ATP PP i cAMP cAMP cAMP cAMP cAMP cAMP cAMP cAMP cAMP Magnesium cAMP cAMP cAMP cAMP G protein-coupled receptor PKA Regulated Pathways Active PKA Hormone Inactive PKA
true true true Adenylate cyclase type 10 true Adenylate cyclase type 10 cAMP-dependent protein kinase catalytic subunit beta CPD-8587 BioCyc G protein-coupled receptor Protein kinase A catalytic subunit C00035 KEGG Compound Guanine nucleotide-binding protein alpha-beta-gamma direct_interaction 1.0 1.0 Q5JWF2 UniProt HMDB0000250 HMDB SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS Guanine nucleotide-binding protein G(T) subunit gamma-T1 Protein kinase A regulatory subunit Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Interaction467 Gαs activates Guanine nucleotide-binding protein alpha-beta-gamma HMDB0000538 HMDB C00044 KEGG Compound Interaction466 Guanine nucleotide-binding protein alpha-beta-gamma activates Guanine nucleotide-binding protein gamma-beta 1.0 ATP BioCyc P63092 UniProt Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas ReactionCatalysis101096 ACTIVATION 559142 ChemSpider Cytoplasm 1.0 C10H12N5O6P cAMP 329.05252 cAMP-dependent protein kinase catalytic subunit beta CHEBI:15422 ChEBI 1.0 cAMP-dependent protein kinase type II-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit Homo sapiens 5742 ChemSpider cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-beta regulatory subunit 1.0 C00575 KEGG Compound Guanosine diphosphate 1.0 1.0 cAMP-dependent protein kinase type I-alpha regulatory subunit Guanosine triphosphate Guanine nucleotide-binding protein G(T) subunit gamma-T1 SMP0063764 SMPDB 1.0 C10H16N5O13P3 Adenosine triphosphate 506.99576 Q96PN6 UniProt O4P Phosphate 94.95342 G protein-coupled receptor 8977 PubChem-compound 5851 ChemSpider 6830 PubChem-compound cAMP-dependent protein kinase type II-alpha regulatory subunit C10H15N5O11P2 Guanosine diphosphate 443.02432 Pyrophosphate SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O PPI BioCyc 1.0 true 9606 TAXONOMY 4.0 1.0 Activation of cAMP-dependent protein kinase, PKA C10H16N5O14P3 Guanosine triphosphate 522.99066 P62873 UniProt cAMP-dependent protein kinase type I-alpha regulatory subunit 8630 ChemSpider cAMP-dependent protein kinase type II-beta regulatory subunit HMDB0000058 HMDB SMILES [O-]P([O-])([O-])=O 1.0 P13861 UniProt SubPathwayInteraction57765 SubPathway57765Reaction SubPathwayReaction cAMP-dependent protein kinase catalytic subunit alpha 1.0 1.0 true 1.0 C00009 KEGG Compound 2.0 P31321 UniProt P10644 UniProt Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 14265-44-2 CAS 1.0 1.0 PKA Regulated Pathways SubPathway 6569 ChemSpider P31323 UniProt HMDB0001429 HMDB 2.0 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O P22694 UniProt CHEBI:18361 ChEBI CHEBI:17552 ChEBI SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 P63211 UniProt GTP BioCyc CHEBI:18367 ChEBI 1032 ChemSpider Phosphate 1.0 C00002 KEGG Compound P22612 UniProt GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE BioCyc cAMP-dependent protein kinase type I-beta regulatory subunit HMDB0001273 HMDB true Protein kinase A 644102 PubChem-compound CHEBI:17489 ChEBI 1.0 CAMP BioCyc 1.0 Adenosine triphosphate SMILES NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1 cAMP-dependent protein kinase catalytic subunit gamma C00013 KEGG Compound HMDB0001201 HMDB Guanine nucleotide-binding protein gamma-beta O7P2 Pyrophosphate 173.91193 5957 PubChem-compound 1.0 86-01-1 CAS 1061 PubChem-compound 6076 PubChem-compound CHEBI:15996 ChEBI 56-65-5 CAS true cAMP-dependent protein kinase catalytic subunit alpha PW064756 PathWhiz Reaction110890 false G protein-coupled receptor + Guanine nucleotide-binding protein alpha-beta-gamma + Guanosine diphosphate + Guanosine triphosphate → Adenylate Cyclase + Guanosine diphosphate + Guanosine triphosphate + Gαs LEFT_TO_RIGHT GO:0005737 GENE ONTOLOGY P17612 UniProt 146-91-8 CAS 60-92-4 CAS Reaction110892 false Guanosine triphosphate + Gαs → Guanosine diphosphate + Gαs + Phosphate LEFT_TO_RIGHT Reaction110893 false Protein kinase A + 4 cAMP ↔ 2 Protein kinase A catalytic subunit + 2 Protein kinase A regulatory subunit REVERSIBLE Reaction110775 false Adenosine triphosphate → Pyrophosphate + cAMP LEFT_TO_RIGHT cAMP GNAS GNGT1 GNB1 GNGT1 GNB1 GNAS GNAS ADCY10 PRKACA PRKACB PRKACG PRKAR1B PRKAR2A PRKAR1A PRKACA PRKACB Guanosine diphosphate Guanosine triphosphate Guanosine triphosphate Guanosine diphosphate Phosphate Guanosine diphosphate Adenosine triphosphate Pyrophosphate cAMP G protein-coupled receptor PKA Regulated Pathways