Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Small Molecule Pathway Database.
Loading Pathway...
4.2.1.17 false 4.2.1.17 (3S)-3-hydroxyacyl-CoA + NAD → Hydrogen Ion + NADH + a 3-oxoacyl-CoA  LEFT_TO_RIGHT 2.3.1.16 false 2.3.1.16 Coenzyme A + a 3-oxoacyl-CoA  → Acetyl-CoA + a 2,3,4-saturated fatty acyl CoA  LEFT_TO_RIGHT 4.2.1.17 false 4.2.1.17 a cis-3-enoyl-CoA  → a trans-2-enoyl-CoA  LEFT_TO_RIGHT 4.2.1.17 false 4.2.1.17 a trans-2-enoyl-CoA  → (3S)-3-hydroxyacyl-CoA + Water LEFT_TO_RIGHT 6.2.1.3 false 6.2.1.3 Adenosine triphosphate + Coenzyme A + a 2,3,4- saturated fatty acid → Adenosine monophosphate + Pyrophosphate + a 2,3,4-saturated fatty acyl CoA  LEFT_TO_RIGHT 1.0 a 2,3,4-saturated fatty acyl CoA  Reaction2905 false Hydrogen Ion + a 2,3,4-saturated fatty acyl CoA  + an oxidized electron-transfer flavoprotein  → Reduced electron-transfer flavoprotein + a trans-2-enoyl-CoA  LEFT_TO_RIGHT a 2,3,4-saturated fatty acyl CoA  C23H38N7O17P3S Acetyl-CoA 809.1258 Long-chain-fatty-acid--CoA ligase 937 ChemSpider SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O HMDB00250 HMDB 1.0 5682 ChemSpider Reduced electron-transfer flavoprotein SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Fatty acid oxidation complex subunit alpha_ NADH AMP BioCyc Water 439153 PubChem-compound SMILES O C10H14N5O7P Adenosine monophosphate 347.06308 Pyrophosphate a 3-oxoacyl-CoA  SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 1.0 SMP00781 SMPDB 14000-31-8 CAS FadJ component of anaerobic fatty acid oxidation complex a cis-3-enoyl-CoA  CHEBI:16027 ChEBI a trans-2-enoyl-CoA  CO-A BioCyc NAD ATP BioCyc 72-89-9 CAS Coenzyme A 3-ketoacyl-CoA thiolase 1.0 C21H36N7O16P3S Coenzyme A 767.11523 1.0 Short-chain-fatty-acid--CoA ligase 6816 PubChem-compound 559142 ChemSpider 1.0 HMDB00538 HMDB CHEBI:15846 ChEBI CHEBI:15422 ChEBI (3S)-3-hydroxyacyl-CoA 6557 ChemSpider HMDB01206 HMDB 1.0 P69451 UniProt 5742 ChemSpider 1038 PubChem-compound SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N Fatty acid oxidation complex subunit alpha 7732-18-5 CAS 388299 ChemSpider 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 HMDB59597 HMDB Adenosine monophosphate 1.0 HMDB00902 HMDB 1.0 CHEBI:16908 ChEBI 5858 ChemSpider C10H16N5O13P3 Adenosine triphosphate 506.99576 a trans-2-enoyl-CoA  1.0 3-ketoacyl-CoA thiolase_ Acetyl-CoA 1.0 2,3-dehydroadipyl-CoA hydratase 1.0 1010 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Long-chain-fatty-acid--CoA ligase PPI BioCyc a cis-3-enoyl-CoA  a 3-oxoacyl-CoA  962 PubChem-compound 1.0 HMDB01423 HMDB Hydrogen Ion P76082 UniProt 392413 ChemSpider 2.0 CHEBI:5086 ChEBI 5893 PubChem-compound Adenosine triphosphate HMDB02111 HMDB 58-68-4 CAS C00080 KEGG Compound Reduced electron-transfer flavoprotein 1.0 CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] C00001 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O CHEBI:18361 ChEBI Fatty acid oxidation complex subunit alpha_ C00004 KEGG Compound C00003 KEGG Compound C00002 KEGG Compound 1.0 ReactionCatalysis2868 ACTIVATION Fatty acid oxidation complex subunit alpha ReactionCatalysis2869 ACTIVATION a 2,3,4- saturated fatty acid 1.0 an oxidized electron-transfer flavoprotein  fatty acid oxidation HMDB01487 HMDB 644102 PubChem-compound a 2,3,4- saturated fatty acid 444493 PubChem-compound C21H28N7O14P2 NAD 664.11694 6083 PubChem-compound (3S)-3-hydroxyacyl-CoA P21151 UniProt C00010 KEGG Compound acetyl-CoA C-acyltransferase 3-ketoacyl-CoA thiolase_ 3-ketoacyl-CoA thiolase C00013 KEGG Compound Short-chain-fatty-acid--CoA ligase O7P2 Pyrophosphate 173.91193 ReactionCatalysis2874 ACTIVATION B7L9A7 UniProt an oxidized electron-transfer flavoprotein  ACETYL-COA BioCyc C21H29N7O14P2 NADH 665.12476 H2O Water 18.010565 5957 PubChem-compound 2,3-dehydroadipyl-CoA hydratase PW000758 PathWhiz P76503 UniProt 1.0 ReactionCatalysis2871 ACTIVATION NADH BioCyc ReactionCatalysis2870 ACTIVATION ReactionCatalysis2873 ACTIVATION P77399 UniProt ReactionCatalysis2872 ACTIVATION NAD BioCyc HMDB00045 HMDB H Hydrogen Ion 1.007825 56-65-5 CAS C00020 KEGG Compound 53-84-9 CAS CHEBI:15351 ChEBI C00024 KEGG Compound 85-61-0 CAS P38135 UniProt Fatty acid oxidation complex subunit alpha 2,3- dehydroadipyl- CoA hydratase 2,3- dehydroadipyl- CoA hydratase 3-ketoacyl-CoA thiolase_ 3-ketoacyl-CoA thiolase CoA ATP AMP PP i H + H 2 O NAD NADH H + CoA Acetyl-CoA a 2,3,4- saturated fatty acid a 2,3,4-saturated fatty acyl CoA an oxidized electron- transfer flavoprotein Reduced electron- transfer flavoprotein a trans-2- enoyl-CoA a cis-3-enoyl-CoA (3S)-3- hydroxyacyl- CoA a 3-oxoacyl-CoA a 2,3,4-saturated fatty acyl CoA Long-chain- fatty-acid-- CoA ligase Short-chain- fatty-acid-- CoA ligase Fatty acid oxidation complex subunit alpha_
4.2.1.17 false 4.2.1.17 (3S)-3-hydroxyacyl-CoA + NAD → Hydrogen Ion + NADH + a 3-oxoacyl-CoA  LEFT_TO_RIGHT 2.3.1.16 false 2.3.1.16 Coenzyme A + a 3-oxoacyl-CoA  → Acetyl-CoA + a 2,3,4-saturated fatty acyl CoA  LEFT_TO_RIGHT 4.2.1.17 false 4.2.1.17 a cis-3-enoyl-CoA  → a trans-2-enoyl-CoA  LEFT_TO_RIGHT 4.2.1.17 false 4.2.1.17 a trans-2-enoyl-CoA  → (3S)-3-hydroxyacyl-CoA + Water LEFT_TO_RIGHT 6.2.1.3 false 6.2.1.3 Adenosine triphosphate + Coenzyme A + a 2,3,4- saturated fatty acid → Adenosine monophosphate + Pyrophosphate + a 2,3,4-saturated fatty acyl CoA  LEFT_TO_RIGHT 1.0 a 2,3,4-saturated fatty acyl CoA  Reaction2905 false Hydrogen Ion + a 2,3,4-saturated fatty acyl CoA  + an oxidized electron-transfer flavoprotein  → Reduced electron-transfer flavoprotein + a trans-2-enoyl-CoA  LEFT_TO_RIGHT a 2,3,4-saturated fatty acyl CoA  C23H38N7O17P3S Acetyl-CoA 809.1258 Long-chain-fatty-acid--CoA ligase 937 ChemSpider SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O HMDB00250 HMDB 1.0 5682 ChemSpider Reduced electron-transfer flavoprotein SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O CHEBI:1146900 ChEBI Fatty acid oxidation complex subunit alpha_ NADH AMP BioCyc Water 439153 PubChem-compound SMILES O C10H14N5O7P Adenosine monophosphate 347.06308 Pyrophosphate a 3-oxoacyl-CoA  SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 1.0 http://identifiers.org/smpdb/SMP00781 SMPDB 14000-31-8 CAS FadJ component of anaerobic fatty acid oxidation complex a cis-3-enoyl-CoA  CHEBI:16027 ChEBI a trans-2-enoyl-CoA  CO-A BioCyc NAD ATP BioCyc 72-89-9 CAS Coenzyme A 3-ketoacyl-CoA thiolase 1.0 C21H36N7O16P3S Coenzyme A 767.11523 1.0 Short-chain-fatty-acid--CoA ligase 6816 PubChem-compound 559142 ChemSpider 1.0 HMDB00538 HMDB CHEBI:15846 ChEBI CHEBI:15422 ChEBI (3S)-3-hydroxyacyl-CoA 6557 ChemSpider HMDB01206 HMDB 1.0 P69451 UniProt 5742 ChemSpider 1038 PubChem-compound SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N Fatty acid oxidation complex subunit alpha 7732-18-5 CAS 388299 ChemSpider 61-19-8 CAS SMILES NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1 HMDB59597 HMDB Adenosine monophosphate 1.0 HMDB00902 HMDB 1.0 CHEBI:16908 ChEBI 5858 ChemSpider C10H16N5O13P3 Adenosine triphosphate 506.99576 a trans-2-enoyl-CoA  1.0 3-ketoacyl-CoA thiolase_ Acetyl-CoA 1.0 2,3-dehydroadipyl-CoA hydratase 1.0 1010 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS Long-chain-fatty-acid--CoA ligase PPI BioCyc a cis-3-enoyl-CoA  a 3-oxoacyl-CoA  962 PubChem-compound 1.0 HMDB01423 HMDB Hydrogen Ion P76082 UniProt 392413 ChemSpider 2.0 CHEBI:5086 ChEBI 5893 PubChem-compound Adenosine triphosphate HMDB02111 HMDB 58-68-4 CAS C00080 KEGG Compound Reduced electron-transfer flavoprotein 1.0 CHEBI:15377 ChEBI CHEBI:15378 ChEBI SMILES [H+] C00001 KEGG Compound SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O CHEBI:18361 ChEBI Fatty acid oxidation complex subunit alpha_ C00004 KEGG Compound C00003 KEGG Compound C00002 KEGG Compound 1.0 ReactionCatalysis2868 ACTIVATION Fatty acid oxidation complex subunit alpha ReactionCatalysis2869 ACTIVATION a 2,3,4- saturated fatty acid 1.0 an oxidized electron-transfer flavoprotein  fatty acid oxidation HMDB01487 HMDB 644102 PubChem-compound a 2,3,4- saturated fatty acid 444493 PubChem-compound C21H28N7O14P2 NAD 664.11694 6083 PubChem-compound (3S)-3-hydroxyacyl-CoA P21151 UniProt C00010 KEGG Compound acetyl-CoA C-acyltransferase 3-ketoacyl-CoA thiolase_ 3-ketoacyl-CoA thiolase C00013 KEGG Compound Short-chain-fatty-acid--CoA ligase O7P2 Pyrophosphate 173.91193 ReactionCatalysis2874 ACTIVATION B7L9A7 UniProt an oxidized electron-transfer flavoprotein  ACETYL-COA BioCyc C21H29N7O14P2 NADH 665.12476 H2O Water 18.010565 5957 PubChem-compound 2,3-dehydroadipyl-CoA hydratase PW000758 PathWhiz P76503 UniProt 1.0 ReactionCatalysis2871 ACTIVATION NADH BioCyc ReactionCatalysis2870 ACTIVATION ReactionCatalysis2873 ACTIVATION P77399 UniProt ReactionCatalysis2872 ACTIVATION NAD BioCyc HMDB00045 HMDB H Hydrogen Ion 1.007825 56-65-5 CAS C00020 KEGG Compound 53-84-9 CAS CHEBI:15351 ChEBI C00024 KEGG Compound 85-61-0 CAS P38135 UniProt fadB paaF paaF fadI fadA Coenzyme A Adenosine triphosphate Adenosine monophosphate Pyrophosphate Hydrogen Ion Water NAD NADH Hydrogen Ion Coenzyme A Acetyl-CoA a 2,3,4- saturated fatty acid a 2,3,4-saturated fatty acyl CoA an oxidized electron- transfer flavoprotein Reduced electron- transfer flavoprotein a trans-2- enoyl-CoA a cis-3-enoyl-CoA (3S)-3- hydroxyacyl- CoA a 3-oxoacyl-CoA a 2,3,4-saturated fatty acyl CoA fadD fadK fadJ