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α-L-rhamnopyranose 1.0 C6H12O5 L-rhamnulofuranose 164.06847 6022 PubChem-compound C9H19O5P L-rhamnulose 1-phosphate 238.09702 C3H6O2 (S)-lactaldehyde 74.03678 1.0 C6H11O8P L-fuculose 1-phosphate 242.02025 C6H12O5 L-fuculose 164.06847 CHEBI:42548 ChEBI C6H12O5 α-L-fucopyranose 164.06847 Lactaldehyde dehydrogenase C6H12O5 β-L-fucopyranose 164.06847 937 ChemSpider C3H8O2 (S)-Propane-1,2-diol 76.05243 96860 ChemSpider HMDB01341 HMDB 1.0 NADH 2.0 439153 PubChem-compound Lactaldehyde reductase SMILES O 1.0 Transport363 false α-L-rhamnopyranose (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 1.0 Reduced acceptor 1.0 NAD ATP BioCyc HMDB01473 HMDB 1.0 Dihydroxyacetone phosphate 1.0 C3H7O6P Dihydroxyacetone phosphate 169.99803 1.0 Pyruvic acid CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 P32170 UniProt P32171 UniProt SMP00846 SMPDB 1.0 P25553 UniProt 5742 ChemSpider 1038 PubChem-compound CHEBI:15022 ChEBI GO:0005829 GENE ONTOLOGY HMDB59597 HMDB L-fucose isomerase 1.0 HMDB00902 HMDB 1.0 CHEBI:16908 ChEBI HMDB00243 HMDB 1.0 1010 ChemSpider L-fuculose phosphate aldolase L-LACTATE BioCyc β-L-rhamnopyranose 4.0 PW000826 PathWhiz Hydrogen Ion PW000785 PathWhiz α-L-rhamnopyranose C00111 KEGG Compound β-L-rhamnopyranose Cytosol keto-L-rhamnulose L-fucose mutarotase Adenosine triphosphate 58-68-4 CAS P33232 UniProt C00008 KEGG Compound 4.0 Hydrogen Ion 4.0 oxidized electron acceptor L-rhamnose mutarotase C00001 KEGG Compound Lactaldehyde reductase L-rhamnose isomerase C00004 KEGG Compound C00003 KEGG Compound C00002 KEGG Compound 1031 ChemSpider 1.0 57-04-5 CAS CHEBI:29002 ChEBI L-rhamnose-proton symporter 1.0 C21H28N7O14P2 NAD 664.11694 5.3.1.14 false 5.3.1.14 β-L-rhamnopyranose → keto-L-rhamnulose LEFT_TO_RIGHT 107689 PubChem-compound Reaction2969 true keto-L-rhamnulose → L-rhamnulofuranose LEFT_TO_RIGHT P32169 UniProt 1.0 SMP00807 SMPDB CHEBI:58313 ChEBI aldehyde dehydrogenase A, NAD-linked L-fucose mutarotase L-1,2-propanediol oxidoreductase L-fuculose-phosphate aldolase C21H29N7O14P2 NADH 665.12476 α-L-rhamnopyranose rhamnulose-1-phosphate aldolase L-fucose isomerase 5957 PubChem-compound 1.0 5.1.3.32 false 5.1.3.32 α-L-rhamnopyranose → β-L-rhamnopyranose LEFT_TO_RIGHT GO:0005620 GENE ONTOLOGY TransportCatalysis378 ACTIVATION L-rhamnulofuranose H Hydrogen Ion 1.007825 L-rhamnulose 1-phosphate (S)-lactaldehyde L-fuculose 1-phosphate P27125 UniProt P32156 UniProt SMP00930 SMPDB L-fucose isomerase C00022 KEGG Compound 56-65-5 CAS C6H12O5 α-L-rhamnopyranose 164.06847 53-84-9 CAS C6H12O5 β-L-rhamnopyranose 164.06847 L-fuculose C6H12O5 keto-L-rhamnulose 164.06847 α-L-fucopyranose β-L-fucopyranose (S)-Propane-1,2-diol Adenosine diphosphate Rhamnulokinase C10H15N5O10P2 Adenosine diphosphate 427.02942 L-fuculose phosphate aldolase Rhamnulose-1-phosphate aldolase L-rhamnose isomerase SMILES C[C@H](O)C(O)=O 1.0 6.0 L-lactate dehydrogenase [cytochrome] SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O glycolysis and pyruvate dehydrogenase SubPathway 5682 ChemSpider SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Water 6.0 ReactionCatalysis2934 ACTIVATION ReactionCatalysis2936 ACTIVATION ReactionCatalysis2935 ACTIVATION 1.0 CHEBI:17617 ChEBI P0AB87 UniProt ReactionCatalysis2938 ACTIVATION ReactionCatalysis2937 ACTIVATION CHEBI:18041 ChEBI ReactionCatalysis2939 ACTIVATION 648 ChemSpider SubPathwayInteraction1177 SubPathway1177Reaction SubPathwayReaction SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O ReactionCatalysis2941 ACTIVATION 2.7.1.5 false 2.7.1.5 Adenosine triphosphate + L-rhamnulofuranose → Adenosine diphosphate + Hydrogen Ion + L-rhamnulose 1-phosphate LEFT_TO_RIGHT ReactionCatalysis2940 ACTIVATION ReactionCatalysis2943 ACTIVATION L-rhamnose-proton symporter ReactionCatalysis2942 ACTIVATION ReactionCatalysis2944 ACTIVATION 1.1.1.77 false 1.1.1.77 (S)-lactaldehyde + Hydrogen Ion + NADH → (S)-Propane-1,2-diol + NAD LEFT_TO_RIGHT HMDB00538 HMDB 1.1.-.- false 1.1.-.- L-Lactic acid + oxidized electron acceptor → Pyruvic acid + Reduced acceptor LEFT_TO_RIGHT 5.1.3.29 false 5.1.3.29 β-L-fucopyranose → α-L-fucopyranose LEFT_TO_RIGHT 1.2.1.22 false 1.2.1.22 (S)-lactaldehyde + NAD + Water → 2 Hydrogen Ion + L-Lactic acid + NADH LEFT_TO_RIGHT 2.7.1.51 false 2.7.1.51 Adenosine triphosphate + L-fuculose → Adenosine diphosphate + Hydrogen Ion + L-fuculose 1-phosphate LEFT_TO_RIGHT 5.3.1.25 false 5.3.1.25 α-L-fucopyranose → L-fuculose LEFT_TO_RIGHT 4.1.2.19 false 4.1.2.19 L-rhamnulose 1-phosphate → (S)-lactaldehyde + Dihydroxyacetone phosphate LEFT_TO_RIGHT 4.1.2.17 false 4.1.2.17 L-fuculose 1-phosphate → (S)-lactaldehyde + Dihydroxyacetone phosphate LEFT_TO_RIGHT CHEBI:15422 ChEBI 668 PubChem-compound fructose metabolism SubPathway L-rhamnose mutarotase 7732-18-5 CAS 388299 ChemSpider 1.0 Reduced acceptor 79-33-4 CAS 1.0 127-17-3 CAS L-fuculokinase HMDB00190 HMDB C10H16N5O13P3 Adenosine triphosphate 506.99576 DIHYDROXY-ACETONE-PHOSPHATE BioCyc P11553 UniProt Lactaldehyde dehydrogenase C00186 KEGG Compound 1.0 SubPathwayInteraction1511 SubPathway1511Reaction SubPathwayReaction CHEBI:16761 ChEBI SMILES CC(=O)C(O)=O SMILES OCC(=O)COP(O)(O)=O CHEBI:42589 ChEBI 962 PubChem-compound 1.0 5800 ChemSpider Rhamnulokinase L-rhamnose isomerase Rhamnulose-1-phosphate aldolase CHEBI:27907 ChEBI 4.0 5893 PubChem-compound HMDB02111 HMDB C00080 KEGG Compound Periplasmic Space P0A9S1 UniProt 1.0 CHEBI:32816 ChEBI CHEBI:15377 ChEBI Transport440 false Hydrogen Ion (→), β-L-rhamnopyranose (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT CHEBI:15378 ChEBI SMILES [H+] L-lactate dehydrogenase [cytochrome] PYRUVATE BioCyc CHEBI:16108 ChEBI SMILES C[C@@H]1O[C@H](O)[C@H](O)[C@H](O)[C@H]1O 58-64-0 CAS SMILES [H][C@@]1(C)O[C@@]([H])(O)[C@]([H])(O)[C@]([H])(O)[C@@]1([H])O SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SMILES CC(O)C(O)C(O)C(=O)CO CHEBI:27586 ChEBI CHEBI:57846 ChEBI 1.0 CHEBI:422 ChEBI L-Lactic acid C3H6O3 L-Lactic acid 90.03169 SMILES CC(O)C(O)C(O)C(=C)COP(C)(O)=C HMDB01487 HMDB SMILES CC1OC(O)(CO)C(O)C1O SMILES C[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O SMILES CC(O)C(O)C(O)C(=O)CO SMILES CC(O)C(O)C(O)C(=O)COP([O-])([O-])=O SMILES [H]C(=O)C(C)O SMILES CC(O)CO SMILES CC1OC(O)C(O)C(O)C1O 2.0 H2O Water 18.010565 fucose and rhamnose degradation NADH BioCyc NAD BioCyc 2.0 PW000913 PathWhiz 1060 PubChem-compound 1.0 Hydrogen Ion L-rhamnose mutarotase oxidized electron acceptor L-fuculokinase P0AEN8 UniProt L-fucose mutarotase 1.0 TransportCatalysis309 ACTIVATION P69922 UniProt 1.0 β-L-rhamnopyranose L-rhamnose- proton symporter L-rhamnose- proton symporter L-rhamnose mutarotase L-rhamnose isomerase Rhamnulokinase Rhamnulose-1- phosphate aldolase L-fuculose phosphate aldolase L-fuculokinase L-fucose isomerase L-fucose mutarotase Lactaldehyde dehydrogenase Lactaldehyde reductase L-lactate dehydrogenase [cytochrome] α-L- rhamnopyranose α-L- rhamnopyranose H + H + H + H + β-L- rhamnopyranose β-L- rhamnopyranose β-L- rhamnopyranose keto-L- rhamnulose L- rhamnulofuranose ATP ADP H + L-rhamnulose 1-phosphate Dihydroxyacetone phosphate (S)- lactaldehyde L-fuculose 1-phosphate Dihydroxyacetone phosphate ATP L-fuculose ADP H + α-L- fucopyranose β-L- fucopyranose NAD H 2 O NADH H + L-Lactic acid NADH H + NAD (S)-Propane- 1,2-diol Pyruvic acid oxidized electron acceptor Reduced acceptor glycolysis and pyruvate dehydrogenase fructose metabolism fructose metabolism Aerobic conditions Anaerobic conditions
α-L-rhamnopyranose 1.0 C6H12O5 L-rhamnulofuranose 164.06847 6022 PubChem-compound C9H19O5P L-rhamnulose 1-phosphate 238.09702 C3H6O2 (S)-lactaldehyde 74.03678 1.0 C6H11O8P L-fuculose 1-phosphate 242.02025 C6H12O5 L-fuculose 164.06847 CHEBI:42548 ChEBI C6H12O5 α-L-fucopyranose 164.06847 Lactaldehyde dehydrogenase C6H12O5 β-L-fucopyranose 164.06847 937 ChemSpider C3H8O2 (S)-Propane-1,2-diol 76.05243 96860 ChemSpider HMDB01341 HMDB 1.0 NADH 2.0 439153 PubChem-compound Lactaldehyde reductase SMILES O 1.0 Transport363 false α-L-rhamnopyranose (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT 1.0 Reduced acceptor 1.0 NAD ATP BioCyc HMDB01473 HMDB 1.0 Dihydroxyacetone phosphate 1.0 C3H7O6P Dihydroxyacetone phosphate 169.99803 1.0 Pyruvic acid CHEBI:15846 ChEBI ADP BioCyc C3H4O3 Pyruvic acid 88.016045 P32170 UniProt P32171 UniProt http://identifiers.org/smpdb/SMP00846 SMPDB 1.0 P25553 UniProt 5742 ChemSpider 1038 PubChem-compound CHEBI:15022 ChEBI GO:0005829 GENE ONTOLOGY HMDB59597 HMDB L-fucose isomerase 1.0 HMDB00902 HMDB 1.0 CHEBI:16908 ChEBI HMDB00243 HMDB 1.0 1010 ChemSpider L-fuculose phosphate aldolase L-LACTATE BioCyc β-L-rhamnopyranose glycolysis and pyruvate dehydrogenase SubPathway 4.0 PW000826 PathWhiz Hydrogen Ion PW000785 PathWhiz α-L-rhamnopyranose C00111 KEGG Compound β-L-rhamnopyranose Cytosol keto-L-rhamnulose L-fucose mutarotase Adenosine triphosphate 58-68-4 CAS P33232 UniProt C00008 KEGG Compound 4.0 Hydrogen Ion 4.0 oxidized electron acceptor L-rhamnose mutarotase C00001 KEGG Compound Lactaldehyde reductase L-rhamnose isomerase C00004 KEGG Compound C00003 KEGG Compound C00002 KEGG Compound 1031 ChemSpider 1.0 57-04-5 CAS CHEBI:29002 ChEBI L-rhamnose-proton symporter 1.0 C21H28N7O14P2 NAD 664.11694 5.3.1.14 false 5.3.1.14 β-L-rhamnopyranose → keto-L-rhamnulose LEFT_TO_RIGHT 107689 PubChem-compound Reaction2969 true keto-L-rhamnulose → L-rhamnulofuranose LEFT_TO_RIGHT P32169 UniProt 1.0 http://identifiers.org/smpdb/SMP00807 SMPDB CHEBI:58313 ChEBI aldehyde dehydrogenase A, NAD-linked L-fucose mutarotase L-1,2-propanediol oxidoreductase L-fuculose-phosphate aldolase C21H29N7O14P2 NADH 665.12476 α-L-rhamnopyranose rhamnulose-1-phosphate aldolase L-fucose isomerase 5957 PubChem-compound 1.0 5.1.3.32 false 5.1.3.32 α-L-rhamnopyranose → β-L-rhamnopyranose LEFT_TO_RIGHT GO:0005620 GENE ONTOLOGY TransportCatalysis378 ACTIVATION L-rhamnulofuranose H Hydrogen Ion 1.007825 L-rhamnulose 1-phosphate (S)-lactaldehyde L-fuculose 1-phosphate P27125 UniProt P32156 UniProt http://identifiers.org/smpdb/SMP00930 SMPDB L-fucose isomerase C00022 KEGG Compound 56-65-5 CAS C6H12O5 α-L-rhamnopyranose 164.06847 53-84-9 CAS C6H12O5 β-L-rhamnopyranose 164.06847 L-fuculose C6H12O5 keto-L-rhamnulose 164.06847 α-L-fucopyranose β-L-fucopyranose (S)-Propane-1,2-diol Adenosine diphosphate Rhamnulokinase C10H15N5O10P2 Adenosine diphosphate 427.02942 L-fuculose phosphate aldolase Rhamnulose-1-phosphate aldolase L-rhamnose isomerase SMILES C[C@H](O)C(O)=O fructose metabolism SubPathway 1.0 6.0 L-lactate dehydrogenase [cytochrome] SMILES NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O 5682 ChemSpider SMILES NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O Water 6.0 ReactionCatalysis2934 ACTIVATION ReactionCatalysis2936 ACTIVATION ReactionCatalysis2935 ACTIVATION 1.0 CHEBI:17617 ChEBI P0AB87 UniProt ReactionCatalysis2938 ACTIVATION ReactionCatalysis2937 ACTIVATION CHEBI:18041 ChEBI ReactionCatalysis2939 ACTIVATION 648 ChemSpider SubPathwayInteraction1177 SubPathway1177Reaction SubPathwayReaction SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O ReactionCatalysis2941 ACTIVATION 2.7.1.5 false 2.7.1.5 Adenosine triphosphate + L-rhamnulofuranose → Adenosine diphosphate + Hydrogen Ion + L-rhamnulose 1-phosphate LEFT_TO_RIGHT ReactionCatalysis2940 ACTIVATION ReactionCatalysis2943 ACTIVATION L-rhamnose-proton symporter ReactionCatalysis2942 ACTIVATION ReactionCatalysis2944 ACTIVATION 1.1.1.77 false 1.1.1.77 (S)-lactaldehyde + Hydrogen Ion + NADH → (S)-Propane-1,2-diol + NAD LEFT_TO_RIGHT HMDB00538 HMDB 1.1.-.- false 1.1.-.- L-Lactic acid + oxidized electron acceptor → Pyruvic acid + Reduced acceptor LEFT_TO_RIGHT 5.1.3.29 false 5.1.3.29 β-L-fucopyranose → α-L-fucopyranose LEFT_TO_RIGHT 1.2.1.22 false 1.2.1.22 (S)-lactaldehyde + NAD + Water → 2 Hydrogen Ion + L-Lactic acid + NADH LEFT_TO_RIGHT 2.7.1.51 false 2.7.1.51 Adenosine triphosphate + L-fuculose → Adenosine diphosphate + Hydrogen Ion + L-fuculose 1-phosphate LEFT_TO_RIGHT 5.3.1.25 false 5.3.1.25 α-L-fucopyranose → L-fuculose LEFT_TO_RIGHT 4.1.2.19 false 4.1.2.19 L-rhamnulose 1-phosphate → (S)-lactaldehyde + Dihydroxyacetone phosphate LEFT_TO_RIGHT 4.1.2.17 false 4.1.2.17 L-fuculose 1-phosphate → (S)-lactaldehyde + Dihydroxyacetone phosphate LEFT_TO_RIGHT CHEBI:15422 ChEBI 668 PubChem-compound L-rhamnose mutarotase 7732-18-5 CAS 388299 ChemSpider 1.0 Reduced acceptor 79-33-4 CAS 1.0 127-17-3 CAS L-fuculokinase HMDB00190 HMDB C10H16N5O13P3 Adenosine triphosphate 506.99576 DIHYDROXY-ACETONE-PHOSPHATE BioCyc P11553 UniProt Lactaldehyde dehydrogenase C00186 KEGG Compound 1.0 SubPathwayInteraction1511 SubPathway1511Reaction SubPathwayReaction CHEBI:16761 ChEBI SMILES CC(=O)C(O)=O SMILES OCC(=O)COP(O)(O)=O CHEBI:42589 ChEBI 962 PubChem-compound 1.0 5800 ChemSpider Rhamnulokinase L-rhamnose isomerase Rhamnulose-1-phosphate aldolase CHEBI:27907 ChEBI 4.0 5893 PubChem-compound HMDB02111 HMDB C00080 KEGG Compound Periplasmic Space P0A9S1 UniProt 1.0 CHEBI:32816 ChEBI CHEBI:15377 ChEBI Transport440 false Hydrogen Ion (→), β-L-rhamnopyranose (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT CHEBI:15378 ChEBI SMILES [H+] L-lactate dehydrogenase [cytochrome] PYRUVATE BioCyc CHEBI:16108 ChEBI SMILES C[C@@H]1O[C@H](O)[C@H](O)[C@H](O)[C@H]1O 58-64-0 CAS SMILES [H][C@@]1(C)O[C@@]([H])(O)[C@]([H])(O)[C@]([H])(O)[C@@]1([H])O SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SMILES CC(O)C(O)C(O)C(=O)CO CHEBI:27586 ChEBI CHEBI:57846 ChEBI 1.0 CHEBI:422 ChEBI L-Lactic acid C3H6O3 L-Lactic acid 90.03169 SMILES CC(O)C(O)C(O)C(=C)COP(C)(O)=C HMDB01487 HMDB SMILES CC1OC(O)(CO)C(O)C1O SMILES C[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O SMILES CC(O)C(O)C(O)C(=O)CO SMILES CC(O)C(O)C(O)C(=O)COP([O-])([O-])=O SMILES [H]C(=O)C(C)O SMILES CC(O)CO SMILES CC1OC(O)C(O)C(O)C1O 2.0 H2O Water 18.010565 fucose and rhamnose degradation NADH BioCyc NAD BioCyc 2.0 PW000913 PathWhiz 1060 PubChem-compound 1.0 Hydrogen Ion L-rhamnose mutarotase oxidized electron acceptor L-fuculokinase P0AEN8 UniProt L-fucose mutarotase 1.0 TransportCatalysis309 ACTIVATION P69922 UniProt 1.0 β-L-rhamnopyranose rhaT rhaT rhaM rhaA rhaB rhaD fucA fucK fucI fucU aldA fucO lldD α-L- rhamnopyranose α-L- rhamnopyranose Hydrogen Ion Hydrogen Ion Hydrogen Ion Hydrogen Ion β-L- rhamnopyranose β-L- rhamnopyranose β-L- rhamnopyranose keto-L- rhamnulose L- rhamnulofuranose Adenosine triphosphate Adenosine diphosphate Hydrogen Ion L-rhamnulose 1-phosphate Dihydroxyacetone phosphate (S)- lactaldehyde L-fuculose 1-phosphate Dihydroxyacetone phosphate Adenosine triphosphate L-fuculose Adenosine diphosphate Hydrogen Ion α-L- fucopyranose β-L- fucopyranose NAD Water NADH Hydrogen Ion L-Lactic acid NADH Hydrogen Ion NAD (S)-Propane- 1,2-diol Pyruvic acid oxidized electron acceptor Reduced acceptor glycolysis and pyruvate dehydrogenase fructose metabolism fructose metabolism