Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Small Molecule Pathway Database.
Loading Pathway...
CHEBI:16015 ChEBI 2.0 30572 ChemSpider 6140 PubChem-compound Catalase-peroxidase 937 ChemSpider 1001 ChemSpider SMP00827 SMPDB CHEBI:16134 ChEBI 63-91-2 CAS phenylalanine transaminase:aspC phenylalanine transaminase:ilvE 1.0 chorismate mutase:pheA SMILES O H3N Ammonia 17.026548 6919011 PubChem-compound 50 ChemSpider 1.0 Transport357 false L-Phenylalanine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT SMP00836 SMPDB TransportCatalysis371 ACTIVATION HMDB00148 HMDB TransportCatalysis370 ACTIVATION 1.0 C02505 KEGG Compound Branched-chain-amino-acid aminotransferase D-phenylalanine D-phenylalanine 1.0 1.0 51 PubChem-compound 1.0 P0A6J5 UniProt 1.0 HMDB10715 HMDB C9H11NO2 D-phenylalanine 165.07898 1038 PubChem-compound 2.0 952 ChemSpider SMILES O[C@@H]1C=CC(=C[C@H]1OC(=C)C(O)=O)C(O)=O GO:0005829 GENE ONTOLOGY 1.0 Ammonia HMDB59597 HMDB D-amino acid dehydrogenase 274 ChemSpider C5H6O5 Oxoglutaric acid 146.02153 C9H8O3 Phenylpyruvic acid 164.04735 1.11.1.21 false 1.11.1.21 L-Phenylalanine + Oxygen ↔ 2-Phenylacetamide + Carbon dioxide REVERSIBLE 1.4.99.1 false 1.4.99.1 Ammonia + Phenylpyruvic acid + cytochrome c nitrite reductase ↔ D-phenylalanine + Water + cytochrome c nitrite reductase REVERSIBLE 2.6.1.57 false 2.6.1.57 L-Phenylalanine + Oxygen ↔ Oxoglutaric acid + Phenylpyruvic acid REVERSIBLE 1.0 Aspartate aminotransferase D-phenylalanine CHEBI:17333 ChEBI Catalase Peroxidase 1010 ChemSpider Aromatic-amino-acid aminotransferase 1028 PubChem-compound P15993 UniProt phenylalanine aminotransferase D-amino acid dehydrogenase small subunit 1.0 Hydrogen Ion Cytosol phenylalanine biosynthesis SubPathway P-protein CPD-6641 BioCyc 217 ChemSpider SMILES OC(=O)C(=O)CC1=CC=CC=C1 L-Glutamic acid C10H10O6 Prephenate 226.04774 PREPHENATE BioCyc SMILES OC(=O)CCC(=O)C(O)=O Oxygen 124-38-9 CAS HMDB00208 HMDB CHEBI:30915 ChEBI C00007 KEGG Compound SubPathwayInteraction1657 SubPathway1657Reaction SubPathwayReaction Hydrogen Ion C00001 KEGG Compound PHENYL-PYRUVATE BioCyc GLT BioCyc 7664-41-7 CAS Cytochrome c-552 1.0 C00254 KEGG Compound C00011 KEGG Compound SMILES O=C=O C00251 KEGG Compound SMILES N[C@@H](CC1=CC=CC=C1)C(O)=O 222 PubChem-compound C00014 KEGG Compound Chorismate biosynthesis SubPathway Prephenate GO:0005620 GENE ONTOLOGY H Hydrogen Ion 1.007825 7680 PubChem-compound HMDB00205 HMDB SubPathwayInteraction1433 SubPathwayReaction SubPathway1433Reaction SMP00938 SMPDB C00026 KEGG Compound C00025 KEGG Compound 7397 ChemSpider 2-Phenylacetamide Inner membrane protein yddG C8H9NO 2-Phenylacetamide 135.06842 SMILES NC(CC1=CC=CC=C1)C(O)=O D-amino acid dehydrogenase small subunit P13029 UniProt Aromatic-amino-acid aminotransferase 328-50-7 CAS Reaction2860 false Hydrogen Ion + Prephenate → Carbon dioxide + Phenylpyruvic acid + Water LEFT_TO_RIGHT Water P0AB80 UniProt 2.6.1.42 false 2.6.1.42 L-Glutamic acid + Phenylpyruvic acid → L-Phenylalanine + Oxoglutaric acid LEFT_TO_RIGHT CHEBI:16666 ChEBI 997 PubChem-compound 5.4.99.5 false 5.4.99.5 Chorismate → Prephenate LEFT_TO_RIGHT C00166 KEGG Compound L-Phenylalanine ReactionCatalysis2819 ACTIVATION C10H10O6 Chorismate 226.04774 Uncharacterized protein YbjE 2.0 HMDB12199 HMDB ReactionCatalysis2820 ACTIVATION SMILES NC(=O)CC1=CC=CC=C1 ReactionCatalysis2822 ACTIVATION ReactionCatalysis2821 ACTIVATION 1.0 Cytochrome c-552 11542 ChemSpider P04693 UniProt L-Phenylalanine Aromatic amino acid transport protein AroP 7732-18-5 CAS P0ABK9 UniProt Chorismate 617-12-9 CAS O2 Oxygen 31.98983 1.0 AMMONIA BioCyc SMILES N 56-86-0 CAS 6.0 4.0 C5H9NO4 L-Glutamic acid 147.05316 156-06-9 CAS 33032 PubChem-compound P0A9J8 UniProt CHEBI:16526 ChEBI CHEBI:17295 ChEBI Catalase-peroxidase 1.0 7782-44-7 CAS Inner membrane protein yddG HMDB01967 HMDB Transport428 false L-Phenylalanine (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Periplasmic Space LEFT_TO_RIGHT PHE BioCyc Transport427 false D-phenylalanine (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Periplasmic Space LEFT_TO_RIGHT 962 PubChem-compound CPD-9517 BioCyc 103-81-1 CAS 2-KETOGLUTARATE BioCyc C9H11NO2 L-Phenylalanine 165.07898 CO2 Carbon dioxide 43.98983 Branched-chain-amino-acid aminotransferase HMDB00051 HMDB HMDB02111 HMDB C00079 KEGG Compound C00080 KEGG Compound 1.0 972 ChemSpider SMILES O=O Periplasmic Space HMDB12283 HMDB 126-49-8 CAS Oxoglutaric acid Phenylpyruvic acid Phenylalanine metabolism SMILES N[C@@H](CCC(O)=O)C(O)=O Uncharacterized protein YbjE PW000816 PathWhiz CHEBI:15377 ChEBI CHEBI:15379 ChEBI CHEBI:15378 ChEBI SMILES [H+] 1.0 5910 ChemSpider P75826 UniProt 1.0 PW000807 PathWhiz 280 PubChem-compound PW000921 PathWhiz ReactionCatalysis3433 ACTIVATION ReactionCatalysis3434 ACTIVATION ReactionCatalysis3432 ACTIVATION 1.0 HMDB00159 HMDB Aspartate aminotransferase CHEBI:30851 ChEBI SMILES OC1C=CC(CC(=O)C(O)=O)(C=C1)C(O)=O 1.0 P46136 UniProt 2.0 H2O Water 18.010565 HMDB01377 HMDB 977 PubChem-compound Hydrogen Ion Carbon dioxide L-Phenylalanine 12039 PubChem-compound CHEBI:16562 ChEBI P00509 UniProt 1.0 P-protein Aromatic amino acid transport protein AroP TransportCatalysis303 ACTIVATION Aromatic amino acid transport protein AroP Inner membrane protein yddG Uncharacterized protein YbjE P-protein P-protein Branched- chain-amino- acid aminotransferase Aspartate aminotransferase Aromatic- amino-acid aminotransferase Catalase- peroxidase Cytochrome c-552 Cytochrome c-552 D-amino acid dehydrogenase small subunit L-Phenylalanine L-Phenylalanine H + H + D-phenylalanine D-phenylalanine L-Phenylalanine Chorismate Prephenate H + CO 2 H 2 O Phenylpyruvic acid L-Glutamic acid Oxoglutaric acid L-Phenylalanine O 2 Oxoglutaric acid Phenylpyruvic acid L-Phenylalanine O 2 CO 2 2- Phenylacetamide NH 3 D-phenylalanine H 2 O Pyridoxal 5'-phosphate ferroheme b Chorismate biosynthesis phenylalanine biosynthesis
CHEBI:16015 ChEBI 2.0 30572 ChemSpider 6140 PubChem-compound Catalase-peroxidase 937 ChemSpider 1001 ChemSpider http://identifiers.org/smpdb/SMP00827 SMPDB CHEBI:16134 ChEBI 63-91-2 CAS phenylalanine transaminase:aspC phenylalanine transaminase:ilvE 1.0 chorismate mutase:pheA SMILES O H3N Ammonia 17.026548 6919011 PubChem-compound 50 ChemSpider 1.0 Transport357 false L-Phenylalanine (→), Hydrogen Ion (→) Transport: Escherichia coli, Periplasmic Space to Escherichia coli, Cytosol LEFT_TO_RIGHT http://identifiers.org/smpdb/SMP00836 SMPDB TransportCatalysis371 ACTIVATION HMDB00148 HMDB TransportCatalysis370 ACTIVATION 1.0 C02505 KEGG Compound Branched-chain-amino-acid aminotransferase D-phenylalanine D-phenylalanine 1.0 1.0 51 PubChem-compound 1.0 P0A6J5 UniProt 1.0 HMDB10715 HMDB C9H11NO2 D-phenylalanine 165.07898 1038 PubChem-compound 2.0 952 ChemSpider SMILES O[C@@H]1C=CC(=C[C@H]1OC(=C)C(O)=O)C(O)=O GO:0005829 GENE ONTOLOGY 1.0 Ammonia HMDB59597 HMDB D-amino acid dehydrogenase 274 ChemSpider C5H6O5 Oxoglutaric acid 146.02153 C9H8O3 Phenylpyruvic acid 164.04735 1.11.1.21 false 1.11.1.21 L-Phenylalanine + Oxygen ↔ 2-Phenylacetamide + Carbon dioxide REVERSIBLE 1.4.99.1 false 1.4.99.1 Ammonia + Phenylpyruvic acid + cytochrome c nitrite reductase ↔ D-phenylalanine + Water + cytochrome c nitrite reductase REVERSIBLE 2.6.1.57 false 2.6.1.57 L-Phenylalanine + Oxygen ↔ Oxoglutaric acid + Phenylpyruvic acid REVERSIBLE 1.0 Aspartate aminotransferase D-phenylalanine CHEBI:17333 ChEBI Catalase Peroxidase 1010 ChemSpider Aromatic-amino-acid aminotransferase 1028 PubChem-compound P15993 UniProt phenylalanine aminotransferase D-amino acid dehydrogenase small subunit 1.0 Hydrogen Ion Cytosol P-protein CPD-6641 BioCyc 217 ChemSpider SMILES OC(=O)C(=O)CC1=CC=CC=C1 L-Glutamic acid C10H10O6 Prephenate 226.04774 PREPHENATE BioCyc SMILES OC(=O)CCC(=O)C(O)=O Oxygen 124-38-9 CAS HMDB00208 HMDB CHEBI:30915 ChEBI C00007 KEGG Compound SubPathwayInteraction1657 SubPathway1657Reaction SubPathwayReaction Hydrogen Ion C00001 KEGG Compound PHENYL-PYRUVATE BioCyc GLT BioCyc 7664-41-7 CAS Cytochrome c-552 1.0 C00254 KEGG Compound C00011 KEGG Compound SMILES O=C=O C00251 KEGG Compound SMILES N[C@@H](CC1=CC=CC=C1)C(O)=O 222 PubChem-compound C00014 KEGG Compound Prephenate GO:0005620 GENE ONTOLOGY H Hydrogen Ion 1.007825 7680 PubChem-compound HMDB00205 HMDB SubPathwayInteraction1433 SubPathwayReaction SubPathway1433Reaction http://identifiers.org/smpdb/SMP00938 SMPDB C00026 KEGG Compound C00025 KEGG Compound 7397 ChemSpider 2-Phenylacetamide Inner membrane protein yddG C8H9NO 2-Phenylacetamide 135.06842 SMILES NC(CC1=CC=CC=C1)C(O)=O D-amino acid dehydrogenase small subunit P13029 UniProt Aromatic-amino-acid aminotransferase 328-50-7 CAS Reaction2860 false Hydrogen Ion + Prephenate → Carbon dioxide + Phenylpyruvic acid + Water LEFT_TO_RIGHT Water P0AB80 UniProt 2.6.1.42 false 2.6.1.42 L-Glutamic acid + Phenylpyruvic acid → L-Phenylalanine + Oxoglutaric acid LEFT_TO_RIGHT CHEBI:16666 ChEBI 997 PubChem-compound 5.4.99.5 false 5.4.99.5 Chorismate → Prephenate LEFT_TO_RIGHT phenylalanine biosynthesis SubPathway C00166 KEGG Compound L-Phenylalanine ReactionCatalysis2819 ACTIVATION C10H10O6 Chorismate 226.04774 Uncharacterized protein YbjE 2.0 HMDB12199 HMDB ReactionCatalysis2820 ACTIVATION SMILES NC(=O)CC1=CC=CC=C1 ReactionCatalysis2822 ACTIVATION ReactionCatalysis2821 ACTIVATION 1.0 Cytochrome c-552 11542 ChemSpider P04693 UniProt L-Phenylalanine Aromatic amino acid transport protein AroP Chorismate biosynthesis SubPathway 7732-18-5 CAS P0ABK9 UniProt Chorismate 617-12-9 CAS O2 Oxygen 31.98983 1.0 AMMONIA BioCyc SMILES N 56-86-0 CAS 6.0 4.0 C5H9NO4 L-Glutamic acid 147.05316 156-06-9 CAS 33032 PubChem-compound P0A9J8 UniProt CHEBI:16526 ChEBI CHEBI:17295 ChEBI Catalase-peroxidase 1.0 7782-44-7 CAS Inner membrane protein yddG HMDB01967 HMDB Transport428 false L-Phenylalanine (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Periplasmic Space LEFT_TO_RIGHT PHE BioCyc Transport427 false D-phenylalanine (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Periplasmic Space LEFT_TO_RIGHT 962 PubChem-compound CPD-9517 BioCyc 103-81-1 CAS 2-KETOGLUTARATE BioCyc C9H11NO2 L-Phenylalanine 165.07898 CO2 Carbon dioxide 43.98983 Branched-chain-amino-acid aminotransferase HMDB00051 HMDB HMDB02111 HMDB C00079 KEGG Compound C00080 KEGG Compound 1.0 972 ChemSpider SMILES O=O Periplasmic Space HMDB12283 HMDB 126-49-8 CAS Oxoglutaric acid Phenylpyruvic acid Phenylalanine metabolism SMILES N[C@@H](CCC(O)=O)C(O)=O Uncharacterized protein YbjE PW000816 PathWhiz CHEBI:15377 ChEBI CHEBI:15379 ChEBI CHEBI:15378 ChEBI SMILES [H+] 1.0 5910 ChemSpider P75826 UniProt 1.0 PW000807 PathWhiz 280 PubChem-compound PW000921 PathWhiz ReactionCatalysis3433 ACTIVATION ReactionCatalysis3434 ACTIVATION ReactionCatalysis3432 ACTIVATION 1.0 HMDB00159 HMDB Aspartate aminotransferase CHEBI:30851 ChEBI SMILES OC1C=CC(CC(=O)C(O)=O)(C=C1)C(O)=O 1.0 P46136 UniProt 2.0 H2O Water 18.010565 HMDB01377 HMDB 977 PubChem-compound Hydrogen Ion Carbon dioxide L-Phenylalanine 12039 PubChem-compound CHEBI:16562 ChEBI P00509 UniProt 1.0 P-protein Aromatic amino acid transport protein AroP TransportCatalysis303 ACTIVATION aroP yddG ybjE pheA pheA ilvE aspC tyrB katG nrfA nrfA dadA L-Phenylalanine L-Phenylalanine Hydrogen Ion Hydrogen Ion D-phenylalanine D-phenylalanine L-Phenylalanine Chorismate Prephenate Hydrogen Ion Carbon dioxide Water Phenylpyruvic acid L-Glutamic acid Oxoglutaric acid L-Phenylalanine Oxygen Oxoglutaric acid Phenylpyruvic acid L-Phenylalanine Oxygen Carbon dioxide 2- Phenylacetamide Ammonia D-phenylalanine Water Chorismate biosynthesis phenylalanine biosynthesis