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CHEBI:16015 ChEBI HMDB01586 HMDB 30572 ChemSpider C23H38N7O17P3S Acetyl-CoA 809.1258 P27830 UniProt 1.0 937 ChemSpider Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase HMDB00250 HMDB SubPathwayInteraction1681 SubPathwayReaction SubPathway1681Reaction HMDB01342 HMDB dTDP-D-glucose SMILES O P27832 UniProt P27833 UniProt P27836 UniProt Pyrophosphate 50 ChemSpider 1.0 SMILES C[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H](O)C1=O SMILES [H]OC1([H])C([H])([H])C([H])(OC1([H])C([H])([H])OP(=O)(O[H])OP(=O)(O[H])O[C@@]1([H])O[C@]([H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)C([H])([H])[H])[C@]([H])(O[H])[C@@]1([H])O[H])N1C([H])=C(C(=O)N([H])C1=O)C([H])([H])[H] HMDB00148 HMDB 4.0 SMILES [H][C@]1(COP(O)(=O)OP(O)(=O)O[C@]2([H])O[C@]([H])(C([O-])=O)[C@@]([H])(O)[C@]([H])(O)[C@]2([H])N=C(C)[O-])O[C@@]([H])(N2C=CC([O-])=NC2=O)[C@]([H])(O)[C@]1([H])O P37744 UniProt CHEBI:16264 ChEBI 1.0 1.0 Secondary Metabolites: enterobacterial common antigen biosynthesis 528-04-1 CAS CHEBI:68492 ChEBI 6816 PubChem-compound 51 PubChem-compound 559142 ChemSpider 4.0 P56258 UniProt C00459 KEGG Compound 388455 ChemSpider HMDB01328 HMDB HMDB01206 HMDB 1.0 365-08-2 CAS 1038 PubChem-compound Lipopolysaccharide biosynthesis protein rffA GO:0005829 GENE ONTOLOGY dTDP-glucose 4,6-dehydratase 2 HMDB59597 HMDB C5H6O5 Oxoglutaric acid 146.02153 64968 PubChem-compound PW000959 PathWhiz 393240 ChemSpider PW000958 PathWhiz N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol C00105 KEGG Compound dTDP-thomosamine 6030 PubChem-compound 6031 PubChem-compound SMP00974 SMPDB SMP00975 SMPDB 164628 PubChem-compound Acetyl-CoA 58493 ChemSpider C00103 KEGG Compound 1010 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS 439165 PubChem-compound P0AAA7 UniProt SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O PPI BioCyc 1.0 144320 ChemSpider HMDB01423 HMDB C10H16N2O11P2 dTDP 402.02292 SMP00903 SMPDB Hydrogen Ion 59-56-3 CAS Probable UDP-N-acetyl-D-mannosaminuronic acid transferase Cytosol 388311 ChemSpider SMP00905 SMPDB L-Glutamic acid Protein wzxE SMILES OC(=O)CCC(=O)C(O)=O HMDB00208 HMDB CHEBI:30915 ChEBI C17H27N3O17P2 Uridine diphosphate-N-acetylglucosamine 607.08154 C9H13N2O9P Uridine 5'-monophosphate 324.03586 1.0 HMDB12307 HMDB C00001 KEGG Compound C00363 KEGG Compound Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate CHEBI:35248 ChEBI CHEBI:18361 ChEBI SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/COP(O)(O)=O Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate pyrophosphate 1.0 GLC-1-P BioCyc GLT BioCyc 1.0 PW000886 PathWhiz PW000884 PathWhiz C00010 KEGG Compound Secondary metabolites: methylerythritol phosphate and polyisoprenoid biosynthesis SubPathway C00015 KEGG Compound 1.0 TDP BioCyc C00013 KEGG Compound Uridine diphosphate-N-acetylglucosamine O7P2 Pyrophosphate 173.91193 Uridine 5'-monophosphate C16H26N2O16P2 dTDP-D-glucose 564.07574 HMDB12306 HMDB GO:0005620 GENE ONTOLOGY Amino sugar and nucleotide sugar metabolism I SubPathway H Hydrogen Ion 1.007825 galactose degradation/Leloir Pathway SubPathway 1.0 SubPathwayInteraction1679 SubPathwayReaction SubPathway1679Reaction SMILES OC[C@H]1OC(OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O dTDP-glucose pyrophosphorylase 2 C00026 KEGG Compound dTDP C00025 KEGG Compound C00024 KEGG Compound dTDP-glucose pyrophosphorylase Thymidine 5'-triphosphate SubPathwayInteraction1680 SubPathway1680Reaction SubPathwayReaction C10H17N2O14P3 Thymidine 5'-triphosphate 481.98926 CHEBI:7137 ChEBI 1.0 TTP BioCyc UDP-ManNAcA 1.0 1.0 53481400 PubChem-compound TDP-Fuc4NAc dTDP-4-dehydro-6-deoxy-D-glucose UDP BioCyc 328-50-7 CAS CHEBI:1146900 ChEBI Water 2.0 4-alpha-L-fucosyltransferase SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)O2)C(=O)NC1=O undecaprenyl-phosphate α-N-acetylglucosaminyl transferase SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS C00842 KEGG Compound 2.7.7.24 false 2.7.7.24 Glucose 1-phosphate + Hydrogen Ion + Thymidine 5'-triphosphate → Pyrophosphate + dTDP-D-glucose LEFT_TO_RIGHT CO-A BioCyc 2.7.7.24 false 2.7.7.24 Glucose 1-phosphate + Hydrogen Ion + Thymidine 5'-triphosphate → Pyrophosphate + dTDP-D-glucose LEFT_TO_RIGHT 4.2.1.46 false 4.2.1.46 dTDP-D-glucose → Water + dTDP-4-dehydro-6-deoxy-D-glucose LEFT_TO_RIGHT C00043 KEGG Compound Uridine 5'-diphosphate 72-89-9 CAS 1.0 Protein wzxE 58-97-9 CAS Coenzyme A dTDP-4-dehydro-6-deoxy-D-glucose transaminase 1.0 C21H36N7O16P3S Coenzyme A 767.11523 1.0 SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O C9H14N2O12P2 Uridine 5'-diphosphate 404.0022 Lipopolysaccharide biosynthesis protein rffC 2.6.1.59 false 2.6.1.59 L-Glutamic acid + dTDP-4-dehydro-6-deoxy-D-glucose → dTDP-thomosamine + Oxoglutaric acid LEFT_TO_RIGHT 2.3.1.210 false 2.3.1.210 dTDP-thomosamine + Acetyl-CoA → Coenzyme A + Hydrogen Ion + TDP-Fuc4NAc LEFT_TO_RIGHT 2.4.1.325 false 2.4.1.325 TDP-Fuc4NAc + Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate pyrophosphate → Hydrogen Ion + Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate + dTDP LEFT_TO_RIGHT TransportCatalysis402 ACTIVATION 2.4.1.180 false 2.4.1.180 N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UDP-ManNAcA → Hydrogen Ion + Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate pyrophosphate + Uridine 5'-diphosphate LEFT_TO_RIGHT 2.7.8.33 false 2.7.8.33 Uridine diphosphate-N-acetylglucosamine + di-trans,octa-cis-undecaprenyl phosphate → N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + Uridine 5'-monophosphate LEFT_TO_RIGHT dTDP-glucose pyrophosphorylase dTDP-glucose pyrophosphorylase 2 SMILES [H][C@]1(O)C[C@@]([H])(O[C@]1([H])COP(O)(=O)OP(O)(=O)O[C@@]1([H])O[C@]([H])(C)[C@]([H])(N)[C@]([H])(O)[C@@]1([H])O)N1C=C(C)C([O-])=NC1=O C55-PP-GLCNAC-MANNACA BioCyc 6557 ChemSpider SMILES [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])COP(O)(=O)OP(O)(=O)OC1([H])O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]1([H])N=C(C)O)=C(\C)CCC=C(C)C C79H129N3O22P2 Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate 1533.8542 C71H116N2O18P2 Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate pyrophosphate 1346.7699 SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS CHEBI:16077 ChEBI 1.0 25245571 PubChem-compound 56-86-0 CAS C5H9NO4 L-Glutamic acid 147.05316 C18H29N3O15P2 TDP-Fuc4NAc 589.10736 33032 PubChem-compound C17H22N3O18P2 UDP-ManNAcA 618.03735 1.0 C16H24N2O15P2 dTDP-4-dehydro-6-deoxy-D-glucose 546.0652 445675 PubChem-compound UDP-N-ACETYL-D-GLUCOSAMINE BioCyc 1.0 DTDP-D-GLUCOSE BioCyc 439324 PubChem-compound Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase 1.0 1.0 962 PubChem-compound C16H26N3O14P2 dTDP-thomosamine 546.08954 C63H105NO12P2 N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 1129.7112 2-KETOGLUTARATE BioCyc 392413 ChemSpider HMDB00290 HMDB 58-98-0 CAS CHEBI:18077 ChEBI CHEBI:18075 ChEBI SMILES OC[C@H]1O[C@H](OP(=O)(O)OP(=O)(O)OC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)[C@H](NC(C)=O)[C@@H](O)[C@@H]1O[C@@H]1O[C@H](C(=O)O)[C@@H](O[C@H]2O[C@H](C)C(NC(C)=O)[C@H](O)[C@H]2O)[C@H](O)[C@@H]1NC(=O)C HMDB00295 HMDB CHEBI:16695 ChEBI di-trans,octa-cis-undecaprenyl phosphate SMILES OC[C@H]1O[C@H](OP(=O)(O)OP(=O)(O)OC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)[C@H](NC(C)=O)[C@@H](O)[C@@H]1O[C@@H]1O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@@H]1NC(=O)C HMDB02111 HMDB C00080 KEGG Compound Periplasmic Space Oxoglutaric acid SMILES N[C@@H](CCC(O)=O)C(O)=O 5809 ChemSpider 5808 ChemSpider CHEBI:15377 ChEBI P0AC78 UniProt CHEBI:15378 ChEBI SMILES [H+] 4-alpha-L-fucosyltransferase HMDB01274 HMDB C6H13O9P Glucose 1-phosphate 260.02972 ReactionCatalysis3679 ACTIVATION ReactionCatalysis3677 ACTIVATION 1.0 ReactionCatalysis3678 ACTIVATION Lipopolysaccharide biosynthesis protein rffA Lipopolysaccharide biosynthesis protein rffC 2196-62-5 CAS 491-97-4 CAS dTDP-glucose pyrophosphorylase 2 dTDP-glucose pyrophosphorylase 644102 PubChem-compound 444493 PubChem-compound P61887 UniProt SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O Glucose 1-phosphate Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate SMILES CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O 4.0 ACETYL-COA BioCyc H2O Water 18.010565 ReactionCatalysis3682 ACTIVATION ReactionCatalysis3683 ACTIVATION ReactionCatalysis3680 ACTIVATION ReactionCatalysis3681 ACTIVATION SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O dTDP-glucose 4,6-dehydratase 2 ReactionCatalysis3684 ACTIVATION HMDB00288 HMDB 1.0 CHEBI:17659 ChEBI UMP BioCyc C55H91O4P di-trans,octa-cis-undecaprenyl phosphate 846.6655 CHEBI:15351 ChEBI Probable UDP-N-acetyl-D-mannosaminuronic acid transferase Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate 85-61-0 CAS Transport468 false Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Periplasmic Space LEFT_TO_RIGHT Protein wzxE Undecaprenyl- phosphate alpha-N- acetylglucosaminyl 1-phosphate transferase Probable UDP-N-acetyl- D- mannosaminuronic acid transferase 4-alpha-L- fucosyltransferase Lipopolysaccharide biosynthesis protein rffC Lipopolysaccharide biosynthesis protein rffA dTDP-glucose 4,6-dehydratase 2 dTDP-glucose pyrophosphorylase dTDP-glucose pyrophosphorylase 2 Undecaprenyl N-acetyl- glucosaminyl- N-acetyl- mannosaminuronate- 4-acetamido- 4,6-dideoxy- D-galactose pyrophosphate Undecaprenyl N-acetyl- glucosaminyl- N-acetyl- mannosaminuronate- 4-acetamido- 4,6-dideoxy- D-galactose pyrophosphate di- trans,octa- cis- undecaprenyl phosphate Uridine diphosphate- N- acetylglucosamine Uridine 5'- monophosphate N-acetyl-α-D- glucosaminyl- diphospho- ditrans,octacis- undecaprenol UDP-ManNAcA Uridine 5'-diphosphate H + Undecaprenyl N-acetyl- glucosaminyl- N-acetyl- mannosaminuronate pyrophosphate TDP-Fuc4NAc H + dTDP Acetyl-CoA dTDP- thomosamine CoA H + L-Glutamic acid dTDP-4- dehydro-6- deoxy-D- glucose Oxoglutaric acid dTDP-D-glucose H 2 O Thymidine 5'-triphosphate H + Glucose 1-phosphate PP i Thymidine 5'-triphosphate H + PP i dTDP-D-glucose Magnesium Pyridoxal 5'-phosphate NAD Secondary metabolites: methylerythritol phosphate and polyisoprenoid biosynthesis Amino sugar and nucleotide sugar metabolism I galactose degradation/Leloir Pathway
CHEBI:16015 ChEBI HMDB01586 HMDB 30572 ChemSpider C23H38N7O17P3S Acetyl-CoA 809.1258 P27830 UniProt 1.0 937 ChemSpider Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase HMDB00250 HMDB SubPathwayInteraction1681 SubPathwayReaction SubPathway1681Reaction HMDB01342 HMDB dTDP-D-glucose SMILES O P27832 UniProt P27833 UniProt P27836 UniProt Pyrophosphate 50 ChemSpider 1.0 SMILES C[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](C[C@@H]2O)N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H](O)C1=O SMILES [H]OC1([H])C([H])([H])C([H])(OC1([H])C([H])([H])OP(=O)(O[H])OP(=O)(O[H])O[C@@]1([H])O[C@]([H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)C([H])([H])[H])[C@]([H])(O[H])[C@@]1([H])O[H])N1C([H])=C(C(=O)N([H])C1=O)C([H])([H])[H] HMDB00148 HMDB 4.0 SMILES [H][C@]1(COP(O)(=O)OP(O)(=O)O[C@]2([H])O[C@]([H])(C([O-])=O)[C@@]([H])(O)[C@]([H])(O)[C@]2([H])N=C(C)[O-])O[C@@]([H])(N2C=CC([O-])=NC2=O)[C@]([H])(O)[C@]1([H])O P37744 UniProt CHEBI:16264 ChEBI 1.0 1.0 Secondary Metabolites: enterobacterial common antigen biosynthesis 528-04-1 CAS CHEBI:68492 ChEBI 6816 PubChem-compound 51 PubChem-compound 559142 ChemSpider galactose degradation/Leloir Pathway SubPathway 4.0 Amino sugar and nucleotide sugar metabolism I SubPathway P56258 UniProt C00459 KEGG Compound 388455 ChemSpider HMDB01328 HMDB HMDB01206 HMDB 1.0 365-08-2 CAS 1038 PubChem-compound Lipopolysaccharide biosynthesis protein rffA GO:0005829 GENE ONTOLOGY dTDP-glucose 4,6-dehydratase 2 HMDB59597 HMDB C5H6O5 Oxoglutaric acid 146.02153 64968 PubChem-compound PW000959 PathWhiz 393240 ChemSpider PW000958 PathWhiz N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol C00105 KEGG Compound dTDP-thomosamine 6030 PubChem-compound 6031 PubChem-compound http://identifiers.org/smpdb/SMP00974 SMPDB http://identifiers.org/smpdb/SMP00975 SMPDB 164628 PubChem-compound Acetyl-CoA 58493 ChemSpider C00103 KEGG Compound 1010 ChemSpider SMILES CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)C(O)C(=O)NCCC(=O)NCCS 439165 PubChem-compound P0AAA7 UniProt SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O PPI BioCyc 1.0 144320 ChemSpider HMDB01423 HMDB C10H16N2O11P2 dTDP 402.02292 http://identifiers.org/smpdb/SMP00903 SMPDB Secondary metabolites: methylerythritol phosphate and polyisoprenoid biosynthesis SubPathway Hydrogen Ion 59-56-3 CAS Probable UDP-N-acetyl-D-mannosaminuronic acid transferase Cytosol 388311 ChemSpider http://identifiers.org/smpdb/SMP00905 SMPDB L-Glutamic acid Protein wzxE SMILES OC(=O)CCC(=O)C(O)=O HMDB00208 HMDB CHEBI:30915 ChEBI C17H27N3O17P2 Uridine diphosphate-N-acetylglucosamine 607.08154 C9H13N2O9P Uridine 5'-monophosphate 324.03586 1.0 HMDB12307 HMDB C00001 KEGG Compound C00363 KEGG Compound Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate CHEBI:35248 ChEBI CHEBI:18361 ChEBI SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/COP(O)(O)=O Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate pyrophosphate 1.0 GLC-1-P BioCyc GLT BioCyc 1.0 PW000886 PathWhiz PW000884 PathWhiz C00010 KEGG Compound C00015 KEGG Compound 1.0 TDP BioCyc C00013 KEGG Compound Uridine diphosphate-N-acetylglucosamine O7P2 Pyrophosphate 173.91193 Uridine 5'-monophosphate C16H26N2O16P2 dTDP-D-glucose 564.07574 HMDB12306 HMDB GO:0005620 GENE ONTOLOGY H Hydrogen Ion 1.007825 1.0 SubPathwayInteraction1679 SubPathwayReaction SubPathway1679Reaction SMILES OC[C@H]1OC(OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O dTDP-glucose pyrophosphorylase 2 C00026 KEGG Compound dTDP C00025 KEGG Compound C00024 KEGG Compound dTDP-glucose pyrophosphorylase Thymidine 5'-triphosphate SubPathwayInteraction1680 SubPathway1680Reaction SubPathwayReaction C10H17N2O14P3 Thymidine 5'-triphosphate 481.98926 CHEBI:7137 ChEBI 1.0 TTP BioCyc UDP-ManNAcA 1.0 1.0 53481400 PubChem-compound TDP-Fuc4NAc dTDP-4-dehydro-6-deoxy-D-glucose UDP BioCyc 328-50-7 CAS CHEBI:1146900 ChEBI Water 2.0 4-alpha-L-fucosyltransferase SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)O2)C(=O)NC1=O undecaprenyl-phosphate α-N-acetylglucosaminyl transferase SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS C00842 KEGG Compound 2.7.7.24 false 2.7.7.24 Glucose 1-phosphate + Hydrogen Ion + Thymidine 5'-triphosphate → Pyrophosphate + dTDP-D-glucose LEFT_TO_RIGHT CO-A BioCyc 2.7.7.24 false 2.7.7.24 Glucose 1-phosphate + Hydrogen Ion + Thymidine 5'-triphosphate → Pyrophosphate + dTDP-D-glucose LEFT_TO_RIGHT 4.2.1.46 false 4.2.1.46 dTDP-D-glucose → Water + dTDP-4-dehydro-6-deoxy-D-glucose LEFT_TO_RIGHT C00043 KEGG Compound Uridine 5'-diphosphate 72-89-9 CAS 1.0 Protein wzxE 58-97-9 CAS Coenzyme A dTDP-4-dehydro-6-deoxy-D-glucose transaminase 1.0 C21H36N7O16P3S Coenzyme A 767.11523 1.0 SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O C9H14N2O12P2 Uridine 5'-diphosphate 404.0022 Lipopolysaccharide biosynthesis protein rffC 2.6.1.59 false 2.6.1.59 L-Glutamic acid + dTDP-4-dehydro-6-deoxy-D-glucose → dTDP-thomosamine + Oxoglutaric acid LEFT_TO_RIGHT 2.3.1.210 false 2.3.1.210 dTDP-thomosamine + Acetyl-CoA → Coenzyme A + Hydrogen Ion + TDP-Fuc4NAc LEFT_TO_RIGHT 2.4.1.325 false 2.4.1.325 TDP-Fuc4NAc + Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate pyrophosphate → Hydrogen Ion + Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate + dTDP LEFT_TO_RIGHT TransportCatalysis402 ACTIVATION 2.4.1.180 false 2.4.1.180 N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UDP-ManNAcA → Hydrogen Ion + Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate pyrophosphate + Uridine 5'-diphosphate LEFT_TO_RIGHT 2.7.8.33 false 2.7.8.33 Uridine diphosphate-N-acetylglucosamine + di-trans,octa-cis-undecaprenyl phosphate → N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + Uridine 5'-monophosphate LEFT_TO_RIGHT dTDP-glucose pyrophosphorylase dTDP-glucose pyrophosphorylase 2 SMILES [H][C@]1(O)C[C@@]([H])(O[C@]1([H])COP(O)(=O)OP(O)(=O)O[C@@]1([H])O[C@]([H])(C)[C@]([H])(N)[C@]([H])(O)[C@@]1([H])O)N1C=C(C)C([O-])=NC1=O C55-PP-GLCNAC-MANNACA BioCyc 6557 ChemSpider SMILES [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])CC\C(C)=C(\[H])COP(O)(=O)OP(O)(=O)OC1([H])O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]1([H])N=C(C)O)=C(\C)CCC=C(C)C C79H129N3O22P2 Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate 1533.8542 C71H116N2O18P2 Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate pyrophosphate 1346.7699 SMILES CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N 7732-18-5 CAS CHEBI:16077 ChEBI 1.0 25245571 PubChem-compound 56-86-0 CAS C5H9NO4 L-Glutamic acid 147.05316 C18H29N3O15P2 TDP-Fuc4NAc 589.10736 33032 PubChem-compound C17H22N3O18P2 UDP-ManNAcA 618.03735 1.0 C16H24N2O15P2 dTDP-4-dehydro-6-deoxy-D-glucose 546.0652 445675 PubChem-compound UDP-N-ACETYL-D-GLUCOSAMINE BioCyc 1.0 DTDP-D-GLUCOSE BioCyc 439324 PubChem-compound Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase 1.0 1.0 962 PubChem-compound C16H26N3O14P2 dTDP-thomosamine 546.08954 C63H105NO12P2 N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 1129.7112 2-KETOGLUTARATE BioCyc 392413 ChemSpider HMDB00290 HMDB 58-98-0 CAS CHEBI:18077 ChEBI CHEBI:18075 ChEBI SMILES OC[C@H]1O[C@H](OP(=O)(O)OP(=O)(O)OC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)[C@H](NC(C)=O)[C@@H](O)[C@@H]1O[C@@H]1O[C@H](C(=O)O)[C@@H](O[C@H]2O[C@H](C)C(NC(C)=O)[C@H](O)[C@H]2O)[C@H](O)[C@@H]1NC(=O)C HMDB00295 HMDB CHEBI:16695 ChEBI di-trans,octa-cis-undecaprenyl phosphate SMILES OC[C@H]1O[C@H](OP(=O)(O)OP(=O)(O)OC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)[C@H](NC(C)=O)[C@@H](O)[C@@H]1O[C@@H]1O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@@H]1NC(=O)C HMDB02111 HMDB C00080 KEGG Compound Periplasmic Space Oxoglutaric acid SMILES N[C@@H](CCC(O)=O)C(O)=O 5809 ChemSpider 5808 ChemSpider CHEBI:15377 ChEBI P0AC78 UniProt CHEBI:15378 ChEBI SMILES [H+] 4-alpha-L-fucosyltransferase HMDB01274 HMDB C6H13O9P Glucose 1-phosphate 260.02972 ReactionCatalysis3679 ACTIVATION ReactionCatalysis3677 ACTIVATION 1.0 ReactionCatalysis3678 ACTIVATION Lipopolysaccharide biosynthesis protein rffA Lipopolysaccharide biosynthesis protein rffC 2196-62-5 CAS 491-97-4 CAS dTDP-glucose pyrophosphorylase 2 dTDP-glucose pyrophosphorylase 644102 PubChem-compound 444493 PubChem-compound P61887 UniProt SMILES CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O Glucose 1-phosphate Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate SMILES CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O 4.0 ACETYL-COA BioCyc H2O Water 18.010565 ReactionCatalysis3682 ACTIVATION ReactionCatalysis3683 ACTIVATION ReactionCatalysis3680 ACTIVATION ReactionCatalysis3681 ACTIVATION SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O dTDP-glucose 4,6-dehydratase 2 ReactionCatalysis3684 ACTIVATION HMDB00288 HMDB 1.0 CHEBI:17659 ChEBI UMP BioCyc C55H91O4P di-trans,octa-cis-undecaprenyl phosphate 846.6655 CHEBI:15351 ChEBI Probable UDP-N-acetyl-D-mannosaminuronic acid transferase Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate 85-61-0 CAS Transport468 false Undecaprenyl N-acetyl-glucosaminyl-N-acetyl-mannosaminuronate-4-acetamido-4,6-dideoxy-D-galactose pyrophosphate (→) Transport: Escherichia coli, Cytosol to Escherichia coli, Periplasmic Space LEFT_TO_RIGHT wzxE wecA wecG wecF rffC rffA rffG rmlA1 rmlA2 Undecaprenyl N-acetyl- glucosaminyl- N-acetyl- mannosaminuronate- 4-acetamido- 4,6-dideoxy- D-galactose pyrophosphate Undecaprenyl N-acetyl- glucosaminyl- N-acetyl- mannosaminuronate- 4-acetamido- 4,6-dideoxy- D-galactose pyrophosphate di- trans,octa- cis- undecaprenyl phosphate Uridine diphosphate- N- acetylglucosamine Uridine 5'- monophosphate N-acetyl-α-D- glucosaminyl- diphospho- ditrans,octacis- undecaprenol UDP-ManNAcA Uridine 5'-diphosphate Hydrogen Ion Undecaprenyl N-acetyl- glucosaminyl- N-acetyl- mannosaminuronate pyrophosphate TDP-Fuc4NAc Hydrogen Ion dTDP Acetyl-CoA dTDP- thomosamine Coenzyme A Hydrogen Ion L-Glutamic acid dTDP-4- dehydro-6- deoxy-D- glucose Oxoglutaric acid dTDP-D-glucose Water Thymidine 5'-triphosphate Hydrogen Ion Glucose 1-phosphate Pyrophosphate Thymidine 5'-triphosphate Hydrogen Ion Pyrophosphate dTDP-D-glucose Secondary metabolites: methylerythritol phosphate and polyisoprenoid biosynthesis Amino sugar and nucleotide sugar metabolism I galactose degradation/Leloir Pathway