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BiologicalState309 Homo sapiens, Cell, Mitochondrial membrane 6022 PubChem-compound 1.0 C2H8NO4P O-Phosphoethanolamine 141.01909 PHOSPHORYL-ETHANOLAMINE BioCyc 3702 TAXONOMY Phosphorylcholine 1014 PubChem-compound 1015 PubChem-compound Choline-phosphate cytidylyltransferase A HMDB00250 HMDB Phosphatidylcholine HMDB01341 HMDB 1.0 1.0 CHEBI:15958 ChEBI 1.0 1.0 6131 PubChem-compound Ethanolamine HMDB00149 HMDB ATP BioCyc an L-1-phosphatidylethanolamine 559142 ChemSpider 1.0 1.0 CDP-ETHANOLAMINE BioCyc ADP BioCyc 110296 ChemSpider HMDB00939 HMDB HMDB01564 HMDB HMDB01565 HMDB C15H23N6O5S S-Adenosylmethionine 399.14505 ReactionCatalysis40036 ACTIVATION 700 PubChem-compound ReactionCatalysis40037 ACTIVATION 5742 ChemSpider C00570 KEGG Compound 1038 PubChem-compound 2.7.7.14 false 2.7.7.14 Cytidine triphosphate + O-Phosphoethanolamine → CDP-Ethanolamine + Pyrophosphate LEFT_TO_RIGHT 2.1.1.71 false 2.1.1.71 Phosphatidyl-N-methylethanolamine + S-Adenosylmethionine → S-Adenosylhomocysteine + phosphatidyl-N-dimethylethanolamine LEFT_TO_RIGHT http://identifiers.org/smpdb/SMP14212 SMPDB 2.1.1.71 false 2.1.1.71 S-Adenosylmethionine + phosphatidyl-N-dimethylethanolamine → Phosphatidylcholine + S-Adenosylhomocysteine LEFT_TO_RIGHT Hydrogen Ion GO:0005829 GENE ONTOLOGY Reaction49908 false an L-1-phosphatidylserine → Carbon dioxide + an L-1-phosphatidylethanolamine LEFT_TO_RIGHT HMDB59597 HMDB 274 ChemSpider Phosphatidyl-N-methylethanolamine Cytidine monophosphate O-Phosphoethanolamine ADENOSYL-HOMO-CYS BioCyc CHEBI:64482 ChEBI C00588 KEGG Compound C00346 KEGG Compound 2.7.8.1 false 2.7.8.1 1,2-diacyl-sn-glycerol + CDP-Ethanolamine → Cytidine monophosphate + an L-1-phosphatidylethanolamine LEFT_TO_RIGHT CHEBI:16000 ChEBI 1010 ChemSpider 2.1.1.17 false 2.1.1.17 S-Adenosylmethionine + an L-1-phosphatidylethanolamine → Phosphatidyl-N-methylethanolamine + S-Adenosylhomocysteine LEFT_TO_RIGHT 1.0 PPI BioCyc S-Adenosylhomocysteine Pyrophosphate 63-37-6 CAS Mitochondrial membrane CHEBI:16732 ChEBI ReactionCatalysis40019 ACTIVATION 1.0 ReactionCatalysis40015 ACTIVATION SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12 979-92-0 CAS Cytosol C00114 KEGG Compound C14H20N6O5S S-Adenosylhomocysteine 384.12158 1071-23-4 CAS 124-38-9 CAS ReactionCatalysis40020 ACTIVATION CDP-Choline ReactionCatalysis40022 ACTIVATION an L-1-phosphatidylserine 1,2-diacyl-sn-glycerol ReactionCatalysis40027 ACTIVATION C00008 KEGG Compound Phosphatidylcholine HMDB00224 HMDB Choline CHEBI:15414 ChEBI ReactionCatalysis40025 ACTIVATION Hydrogen Ion ReactionCatalysis40026 ACTIVATION CTP BioCyc CHEBI:18361 ChEBI C00002 KEGG Compound 13835336 ChemSpider Mitochondrial Inner Membrane SMILES [H][C@]1(COP(O)(=O)OP(O)(=O)OCC[N+](C)(C)C)O[C@@]([H])(N2C=CC(=N)N=C2O)[C@]([H])(O)[C@]1([H])O ReactionCatalysis40033 ACTIVATION C00019 KEGG Compound BiologicalState49 Homo sapiens, Cell, Endoplasmic Reticulum Membrane 1.0 CHEBI:17361 ChEBI S-ADENOSYLMETHIONINE BioCyc 1.0 C00011 KEGG Compound SMILES O=C=O BiologicalState249 Arabidopsis thaliana, Cell, Endoplasmic Reticulum C00013 KEGG Compound O7P2 Pyrophosphate 173.91193 SMILES C[N+](C)(C)CCOP(O)(O)=O 1.0 SMILES NCCOP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(N)=NC1=O 5957 PubChem-compound GO:0005743 GENE ONTOLOGY C9H16N3O14P3 Cytidine triphosphate 482.9845 Pyrophosphate P35790 UniProt Phosphatidylethanolamine N-methyltransferase H Hydrogen Ion 1.007825 388301 ChemSpider CPD-563 BioCyc 56-65-5 CAS C00021 KEGG Compound Phosphatidylcholine Adenosine triphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 Cytidine triphosphate 1.0 PHOSPHORYL-CHOLINE BioCyc C5H14NO Choline 104.10754 C9H14N3O8P Cytidine monophosphate 323.05185 an L-1-phosphatidylethanolamine Carbon dioxide Endoplasmic Reticulum Endoplasmic Reticulum Membrane CL:0000000 CELL TYPE ONTOLOGY 1.0 HMDB00095 HMDB HMDB00097 HMDB HMDB01185 HMDB P49585 UniProt Choline kinase alpha SMILES NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Q9Y6K0 UniProt SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS Phosphatidylethanolamine N-methyltransferase 2.7.1.82 false 2.7.1.82 Adenosine triphosphate + Ethanolamine → Adenosine diphosphate + Hydrogen Ion + O-Phosphoethanolamine LEFT_TO_RIGHT 1.0 2.7.7.15 false 2.7.7.15 Cytidine triphosphate + Phosphorylcholine → CDP-Choline + Pyrophosphate LEFT_TO_RIGHT 2.7.8.2 false 2.7.8.2 1,2-diacyl-sn-glycerol + CDP-Choline → Cytidine monophosphate + Hydrogen Ion + Phosphatidylcholine LEFT_TO_RIGHT Reaction49897 false Adenosine triphosphate + Choline → Adenosine diphosphate + Phosphorylcholine LEFT_TO_RIGHT Phosphorylcholine SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SMILES C[N+](C)(C)CCO SMILES NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O Adenosine diphosphate HMDB00538 HMDB 1.0 Cell 5901 ChemSpider CHEBI:15422 ChEBI Q9UG56 UniProt an L-1-phosphatidylserine 305 PubChem-compound CHEBI:18132 ChEBI C00055 KEGG Compound SMILES NCCOP(O)(O)=O 1.0 Cytidine triphosphate C00063 KEGG Compound GO:0005789 GENE ONTOLOGY ETHANOL-AMINE BioCyc an L-1-phosphatidylethanolamine GO:0005783 GENE ONTOLOGY 1.0 C2H7NO Ethanolamine 61.052765 BiologicalState17 Homo sapiens, Cell, Mitochondrial Inner Membrane 1.0 O-Phosphoethanolamine C10H16N5O13P3 Adenosine triphosphate 506.99576 C04308 KEGG Compound CDP-Choline Ethanolamine-phosphate cytidylyltransferase CHEBI:16526 ChEBI HMDB00082 HMDB an L-1-phosphatidylethanolamine 1.0 Q9UBM1 UniProt Phosphatidylserine decarboxylase proenzyme CHEBI:16761 ChEBI C00189 KEGG Compound 107-73-3 CAS 65-47-4 CAS Ethanolamine-phosphate cytidylyltransferase Q99447 UniProt 3036-18-8 CAS Choline/ethanolaminephosphotransferase 1 CDP-Ethanolamine PW015076 PathWhiz Choline kinase alpha HMDB01967 HMDB Choline-phosphate cytidylyltransferase A 9606 TAXONOMY 31983 ChemSpider phosphatidyl-N-dimethylethanolamine 5800 ChemSpider CO2 Carbon dioxide 43.98983 Choline/ethanolaminephosphotransferase 1 1.0 CMP BioCyc C00080 KEGG Compound 1.0 SMILES NCCO 299 ChemSpider C11H20N4O11P2 CDP-Ethanolamine 446.0604 C5H15NO4P Phosphorylcholine 184.07387 1.0 BiologicalState2 Homo sapiens, Cell, Cytosol CHEBI:17677 ChEBI phosphatidyl-N-dimethylethanolamine 6176 PubChem-compound CHEBI:15378 ChEBI SMILES [H+] 58-64-0 CAS 1.0 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Phosphatidyl-N-methylethanolamine CHEBI:17553 ChEBI C00641 KEGG Compound 123727 PubChem-compound 280 PubChem-compound 1,2-diacyl-sn-glycerol 1.0 644102 PubChem-compound 5941 ChemSpider SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12)C(O)=O 1.0 1.0 25246222 PubChem-compound GO:0031966 GENE ONTOLOGY 990 ChemSpider Phosphatidylcholine Biosynthesis 29908-03-0 CAS CHEBI:15354 ChEBI 1.0 141-43-5 CAS CHEBI:16680 ChEBI Phosphatidylserine decarboxylase proenzyme 62-49-7 CAS 989 ChemSpider S-Adenosylmethionine 24762165 PubChem-compound 1.0 1.0 C14H27N4O11P2 CDP-Choline 489.11514 choline- phosphate cytidylyltransferase Phosphatidylethanolamine N- methyltransferase Phosphatidylethanolamine N- methyltransferase Ethanolamine- phosphate cytidylyltransferase phosphatidylserine decarboxylase choline/ethanolaminephosphotransferase choline/ethanolaminephosphotransferase Phosphatidylethanolamine N- methyltransferase choline/ethanolamine kinase choline/ethanolamine kinase Cytidine triphosphate Phosphorylcholine PP i CDP-Choline S- Adenosylmethionine S- Adenosylhomocysteine S- Adenosylmethionine S- Adenosylhomocysteine Cytidine triphosphate O- Phosphoethanolamine PP i CDP- Ethanolamine CO 2 Cytidine monophosphate Cytidine monophosphate H + S- Adenosylmethionine S- Adenosylhomocysteine Ethanolamine ATP ADP H + Choline ATP ADP Phosphatidyl- N- methylethanolamine phosphatidyl- N- dimethylethanolamine Phosphatidylcholine an L-1- phosphatidylserine an L-1- phosphatidylethanolamine 1,2-diacyl- sn-glycerol an L-1- phosphatidylethanolamine 1,2-diacyl- sn-glycerol Phosphatidylcholine an L-1- phosphatidylethanolamine Endoplasmic Reticulum Membrane Mitochondrial Outer Membrane Cytosol Endoplasmic Reticulum Lumen Mitochondrial Intermembrane Spance Mitochondrial Matrix Mitochondrial Inner Membrane
BiologicalState309 Homo sapiens, Cell, Mitochondrial membrane 6022 PubChem-compound 1.0 C2H8NO4P O-Phosphoethanolamine 141.01909 PHOSPHORYL-ETHANOLAMINE BioCyc 3702 TAXONOMY Phosphorylcholine 1014 PubChem-compound 1015 PubChem-compound Choline-phosphate cytidylyltransferase A HMDB00250 HMDB Phosphatidylcholine HMDB01341 HMDB 1.0 1.0 CHEBI:15958 ChEBI 1.0 1.0 6131 PubChem-compound Ethanolamine HMDB00149 HMDB ATP BioCyc an L-1-phosphatidylethanolamine 559142 ChemSpider 1.0 1.0 CDP-ETHANOLAMINE BioCyc ADP BioCyc 110296 ChemSpider HMDB00939 HMDB HMDB01564 HMDB HMDB01565 HMDB C15H23N6O5S S-Adenosylmethionine 399.14505 ReactionCatalysis40036 ACTIVATION 700 PubChem-compound ReactionCatalysis40037 ACTIVATION 5742 ChemSpider C00570 KEGG Compound 1038 PubChem-compound 2.7.7.14 false 2.7.7.14 Cytidine triphosphate + O-Phosphoethanolamine → CDP-Ethanolamine + Pyrophosphate LEFT_TO_RIGHT 2.1.1.71 false 2.1.1.71 Phosphatidyl-N-methylethanolamine + S-Adenosylmethionine → S-Adenosylhomocysteine + phosphatidyl-N-dimethylethanolamine LEFT_TO_RIGHT http://identifiers.org/smpdb/SMP14212 SMPDB 2.1.1.71 false 2.1.1.71 S-Adenosylmethionine + phosphatidyl-N-dimethylethanolamine → Phosphatidylcholine + S-Adenosylhomocysteine LEFT_TO_RIGHT Hydrogen Ion GO:0005829 GENE ONTOLOGY Reaction49908 false an L-1-phosphatidylserine → Carbon dioxide + an L-1-phosphatidylethanolamine LEFT_TO_RIGHT HMDB59597 HMDB 274 ChemSpider Phosphatidyl-N-methylethanolamine Cytidine monophosphate O-Phosphoethanolamine ADENOSYL-HOMO-CYS BioCyc CHEBI:64482 ChEBI C00588 KEGG Compound C00346 KEGG Compound 2.7.8.1 false 2.7.8.1 1,2-diacyl-sn-glycerol + CDP-Ethanolamine → Cytidine monophosphate + an L-1-phosphatidylethanolamine LEFT_TO_RIGHT CHEBI:16000 ChEBI 1010 ChemSpider 2.1.1.17 false 2.1.1.17 S-Adenosylmethionine + an L-1-phosphatidylethanolamine → Phosphatidyl-N-methylethanolamine + S-Adenosylhomocysteine LEFT_TO_RIGHT 1.0 PPI BioCyc S-Adenosylhomocysteine Pyrophosphate 63-37-6 CAS Mitochondrial membrane CHEBI:16732 ChEBI ReactionCatalysis40019 ACTIVATION 1.0 ReactionCatalysis40015 ACTIVATION SMILES C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12 979-92-0 CAS Cytosol C00114 KEGG Compound C14H20N6O5S S-Adenosylhomocysteine 384.12158 1071-23-4 CAS 124-38-9 CAS ReactionCatalysis40020 ACTIVATION CDP-Choline ReactionCatalysis40022 ACTIVATION an L-1-phosphatidylserine 1,2-diacyl-sn-glycerol ReactionCatalysis40027 ACTIVATION C00008 KEGG Compound Phosphatidylcholine HMDB00224 HMDB Choline CHEBI:15414 ChEBI ReactionCatalysis40025 ACTIVATION Hydrogen Ion ReactionCatalysis40026 ACTIVATION CTP BioCyc CHEBI:18361 ChEBI C00002 KEGG Compound 13835336 ChemSpider Mitochondrial Inner Membrane SMILES [H][C@]1(COP(O)(=O)OP(O)(=O)OCC[N+](C)(C)C)O[C@@]([H])(N2C=CC(=N)N=C2O)[C@]([H])(O)[C@]1([H])O ReactionCatalysis40033 ACTIVATION C00019 KEGG Compound BiologicalState49 Homo sapiens, Cell, Endoplasmic Reticulum Membrane 1.0 CHEBI:17361 ChEBI S-ADENOSYLMETHIONINE BioCyc 1.0 C00011 KEGG Compound SMILES O=C=O BiologicalState249 Arabidopsis thaliana, Cell, Endoplasmic Reticulum C00013 KEGG Compound O7P2 Pyrophosphate 173.91193 SMILES C[N+](C)(C)CCOP(O)(O)=O 1.0 SMILES NCCOP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(N)=NC1=O 5957 PubChem-compound GO:0005743 GENE ONTOLOGY C9H16N3O14P3 Cytidine triphosphate 482.9845 Pyrophosphate P35790 UniProt Phosphatidylethanolamine N-methyltransferase H Hydrogen Ion 1.007825 388301 ChemSpider CPD-563 BioCyc 56-65-5 CAS C00021 KEGG Compound Phosphatidylcholine Adenosine triphosphate C10H15N5O10P2 Adenosine diphosphate 427.02942 Cytidine triphosphate 1.0 PHOSPHORYL-CHOLINE BioCyc C5H14NO Choline 104.10754 C9H14N3O8P Cytidine monophosphate 323.05185 an L-1-phosphatidylethanolamine Carbon dioxide Endoplasmic Reticulum Endoplasmic Reticulum Membrane CL:0000000 CELL TYPE ONTOLOGY 1.0 HMDB00095 HMDB HMDB00097 HMDB HMDB01185 HMDB P49585 UniProt Choline kinase alpha SMILES NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Q9Y6K0 UniProt SMILES [O-]P([O-])(=O)OP([O-])([O-])=O 14000-31-8 CAS Phosphatidylethanolamine N-methyltransferase 2.7.1.82 false 2.7.1.82 Adenosine triphosphate + Ethanolamine → Adenosine diphosphate + Hydrogen Ion + O-Phosphoethanolamine LEFT_TO_RIGHT 1.0 2.7.7.15 false 2.7.7.15 Cytidine triphosphate + Phosphorylcholine → CDP-Choline + Pyrophosphate LEFT_TO_RIGHT 2.7.8.2 false 2.7.8.2 1,2-diacyl-sn-glycerol + CDP-Choline → Cytidine monophosphate + Hydrogen Ion + Phosphatidylcholine LEFT_TO_RIGHT Reaction49897 false Adenosine triphosphate + Choline → Adenosine diphosphate + Phosphorylcholine LEFT_TO_RIGHT Phosphorylcholine SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O SMILES C[N+](C)(C)CCO SMILES NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O Adenosine diphosphate HMDB00538 HMDB 1.0 Cell 5901 ChemSpider CHEBI:15422 ChEBI Q9UG56 UniProt an L-1-phosphatidylserine 305 PubChem-compound CHEBI:18132 ChEBI C00055 KEGG Compound SMILES NCCOP(O)(O)=O 1.0 Cytidine triphosphate C00063 KEGG Compound GO:0005789 GENE ONTOLOGY ETHANOL-AMINE BioCyc an L-1-phosphatidylethanolamine GO:0005783 GENE ONTOLOGY 1.0 C2H7NO Ethanolamine 61.052765 BiologicalState17 Homo sapiens, Cell, Mitochondrial Inner Membrane 1.0 O-Phosphoethanolamine C10H16N5O13P3 Adenosine triphosphate 506.99576 C04308 KEGG Compound CDP-Choline Ethanolamine-phosphate cytidylyltransferase CHEBI:16526 ChEBI HMDB00082 HMDB an L-1-phosphatidylethanolamine 1.0 Q9UBM1 UniProt Phosphatidylserine decarboxylase proenzyme CHEBI:16761 ChEBI C00189 KEGG Compound 107-73-3 CAS 65-47-4 CAS Ethanolamine-phosphate cytidylyltransferase Q99447 UniProt 3036-18-8 CAS Choline/ethanolaminephosphotransferase 1 CDP-Ethanolamine PW015076 PathWhiz Choline kinase alpha HMDB01967 HMDB Choline-phosphate cytidylyltransferase A 9606 TAXONOMY 31983 ChemSpider phosphatidyl-N-dimethylethanolamine 5800 ChemSpider CO2 Carbon dioxide 43.98983 Choline/ethanolaminephosphotransferase 1 1.0 CMP BioCyc C00080 KEGG Compound 1.0 SMILES NCCO 299 ChemSpider C11H20N4O11P2 CDP-Ethanolamine 446.0604 C5H15NO4P Phosphorylcholine 184.07387 1.0 BiologicalState2 Homo sapiens, Cell, Cytosol CHEBI:17677 ChEBI phosphatidyl-N-dimethylethanolamine 6176 PubChem-compound CHEBI:15378 ChEBI SMILES [H+] 58-64-0 CAS 1.0 SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O Phosphatidyl-N-methylethanolamine CHEBI:17553 ChEBI C00641 KEGG Compound 123727 PubChem-compound 280 PubChem-compound 1,2-diacyl-sn-glycerol 1.0 644102 PubChem-compound 5941 ChemSpider SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12)C(O)=O 1.0 1.0 25246222 PubChem-compound GO:0031966 GENE ONTOLOGY 990 ChemSpider Phosphatidylcholine Biosynthesis 29908-03-0 CAS CHEBI:15354 ChEBI 1.0 141-43-5 CAS CHEBI:16680 ChEBI Phosphatidylserine decarboxylase proenzyme 62-49-7 CAS 989 ChemSpider S-Adenosylmethionine 24762165 PubChem-compound 1.0 1.0 C14H27N4O11P2 CDP-Choline 489.11514 Endoplasmic Reticulum Mitochondria PCYT1A PEMT PEMT PCYT2 PISD CEPT1 CEPT1 PEMT CHKA CHKA Cytidine triphosphate Phosphorylcholine Pyrophosphate CDP-Choline S- Adenosylmethionine S- Adenosylhomocysteine S- Adenosylmethionine S- Adenosylhomocysteine Cytidine triphosphate O- Phosphoethanolamine Pyrophosphate CDP- Ethanolamine Carbon dioxide Cytidine monophosphate Cytidine monophosphate Hydrogen Ion S- Adenosylmethionine S- Adenosylhomocysteine Ethanolamine Adenosine triphosphate Adenosine diphosphate Hydrogen Ion Choline Adenosine triphosphate Adenosine diphosphate Phosphatidyl- N- methylethanolamine phosphatidyl- N- dimethylethanolamine Phosphatidylcholine an L-1- phosphatidylserine an L-1- phosphatidylethanolamine 1,2-diacyl- sn-glycerol an L-1- phosphatidylethanolamine 1,2-diacyl- sn-glycerol Phosphatidylcholine an L-1- phosphatidylethanolamine