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Unknown Unknown GTP cyclohydrolase GTP cyclohydrolase GTP cyclohydrolase GTP cyclohydrolase 6-pyruvoyl tetrahydrobiopterin synthase Sepiapterin reductase Sepiapterin reductase Aldose reductase Carbonyl reductase [NADPH] 1 Sepiapterin reductase Carbonyl reductase [NADPH] 1 Sepiapterin reductase Dihydrofolate reductase Sepiapterin reductase Dihydropteridine reductase Guanosine triphosphate Formamidopyrimidine nucleoside triphosphate H2O 2,5-Diaminopyrimidine nucleoside triphosphate Formic acid H2O Formic acid 2,5-Diamino-6-(5'- triphosphoryl-3',4'- trihydroxy-2'-oxopentyl)- amino-4-oxopyrimidine Dihydroneopterin triphosphate H2O Dyspropterin PPPi NADP NADPH 1-hydroxy-2-Oxopropyl tetrahydropterin NADP 6-Lactoyltetrahydropterin NADPH NADP NADPH Sepiapterin NADPH 7,8-Dihydroneopterin NADP NADP NADPH NADP Tetrahydrobiopterin NADPH NADPH NADP H2O Neopterin NAD NADH Dihydrobiopterin NADPH NADP Zinc Zinc Zinc Zinc Zinc Purine Metabolism Cytosol
Unknown Unknown GCH1 GCH1 GCH1 GCH1 PTS SPR SPR AKR1B1 CBR1 SPR CBR1 SPR DHFR SPR QDPR Guanosine triphosphate Formamidopyrimidine nucleoside triphosphate Water 2,5- Diaminopyrimidine nucleoside triphosphate Formic acid Water Formic acid 2,5-Diamino- 6-(5'- triphosphoryl- 3',4'- trihydroxy- 2'- oxopentyl)- amino-4- oxopyrimidine Dihydroneopterin triphosphate Water Dyspropterin PPPi NADP NADPH 1-hydroxy-2- Oxopropyl tetrahydropterin NADP 6- Lactoyltetrahydropterin NADPH NADP NADPH Sepiapterin NADPH 7,8- Dihydroneopterin NADP NADP NADPH NADP Tetrahydrobiopterin NADPH NADPH NADP Water Neopterin NAD NADH Dihydrobiopterin NADPH NADP Purine Metabolism