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Palmitic acid
Biotin
carboxylase
Outer membrane
protein A
Acetyl-coenzyme
A carboxylase
carboxyl
transferase
subunit alpha
Acetyl-coenzyme
A carboxylase
carboxyl
transferase
subunit beta
Biotin carboxyl
carrier protein
of acetyl-CoA
carboxylase
Malonyl
CoA-acyl
carrier protein
transacylase
3-oxoacyl-
[acyl- carrier-
protein]
synthase 3
3-oxoacyl-
[acyl- carrier-
protein]
reductase
(3R)-
hydroxymyristoyl-
[acyl- carrier-
protein]
dehydratase
Enoyl-[acyl-
carrier-
protein]
reductase
[NADH]
3-oxoacyl-
[acyl- carrier-
protein]
synthase 1
3-oxoacyl-
[acyl- carrier-
protein]
reductase
(3R)-
hydroxymyristoyl-
[acyl- carrier-
protein]
dehydratase
Enoyl-[acyl-
carrier-
protein]
reductase
[NADH]
3-oxoacyl-
[acyl- carrier-
protein]
synthase 1
3-oxoacyl-
[acyl- carrier-
protein]
reductase
(3R)-
hydroxymyristoyl-
[acyl- carrier-
protein]
dehydratase
Enoyl-[acyl-
carrier-
protein]
reductase
[NADH]
3-oxoacyl-
[acyl- carrier-
protein]
synthase 1
3-oxoacyl-
[acyl- carrier-
protein]
reductase
(3R)-
hydroxymyristoyl-
[acyl- carrier-
protein]
dehydratase
Enoyl-[acyl-
carrier-
protein]
reductase
[NADH]
3-oxoacyl-
[acyl- carrier-
protein]
synthase 1
3-oxoacyl-
[acyl- carrier-
protein]
reductase
(3R)-
hydroxymyristoyl-
[acyl- carrier-
protein]
dehydratase
Enoyl-[acyl-
carrier-
protein]
reductase
[NADH]
3-oxoacyl-
[acyl- carrier-
protein]
synthase 1
3-oxoacyl-
[acyl- carrier-
protein]
reductase
(3R)-
hydroxymyristoyl-
[acyl- carrier-
protein]
dehydratase
3-oxoacyl-
[acyl- carrier-
protein]
synthase 1
3-oxoacyl-
[acyl- carrier-
protein]
synthase 1
3-oxoacyl-
[acyl- carrier-
protein]
reductase
(3R)-
hydroxymyristoyl-
[acyl- carrier-
protein]
dehydratase
Enoyl-[acyl-
carrier-
protein]
reductase
[NADH]
Acetyl-CoA
Palmitic acid
Palmitic acid
Palmitic acid
HCO
3
-
ATP
ADP
P
i
H
+
Malonyl-CoA
CoA
H
+
Acetyl-CoA
CO
2
CoA
H
+
NADPH
NADP
H
2
O
H
+
NADH
NAD
H
+
CO
2
H
+
NADPH
NADP
H
2
O
H
+
NADH
NAD
H
+
CO
2
H
+
NADPH
NADP
H
2
O
H
+
NADH
NAD
H
+
CO
2
H
+
NADPH
NADP
H
2
O
H
+
NADH
NAD
CO
2
H
+
NADPH
NADP
H
2
O
H
+
NADH
NAD
H
2
O
H
+
Dodecanoic acid
H
+
CO
2
H
+
NADPH
NADP
H
2
O
H
+
NADH
NAD
H
+
CO
2
H
+
NADPH
NADP
H
2
O
H
+
NADH
NAD
H
2
O
H
+
Octanoyl-
[acyl-carrier
protein]
a holo-[acyl-
carrier
protein]
a malonyl-[acp]
acetoacetyl-
[acp]
(R)-3-
hydroxybutanoyl-
[acp]
crotonyl-[acp]
butyryl-[acp]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
hexanoyl- [acp]
(R)-3-
hydroxyhexanoyl-
[acp]
trans
hex-2-enoyl-
[acp]
hexanoyl-
[acyl- carrier-
protein]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
octanoyl- [acp]
(R)-3-
hydroxyoctanoyl-
[acp]
trans
oct-2-enoyl-
[acp]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
decanoyl- [acp]
an (R)-3-
hydroxydecanoyl-
[acp]
a trans-Δ2-
decenoyl- [acp]
decanoyl-[acp]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
dodecanoyl-
[acp]
(R)-3-
hydroxydodecanoyl-
[acp]
trans dodec-2-
enoyl-[acp]
dodecanoyl-
[acp]
a holo-[acyl-
carrier
protein]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
myristoyl-
[acp]
(3R)-3-
hydroxymyristoyl-
[acp]
trans
tetradec-2-
enoyl-[acp]
myristoyl-[acp]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
palmitoyl-
[acp]
(R)-3-
hydroxypalmitoyl-
[acp]
trans
hexadecenoyl-
[acp]
palmitoyl-[acp]
a holo-[acyl-
carrier
protein]
Glycolysis and
Pyruvate
Dehydrogenase
Lipoic Acid
Metabolism
Palmitic acid
accC
ompA
accA
accD
accB
fabD
fabH
fabG
fabZ
fabI
fabB
fabG
fabZ
fabI
fabB
fabG
fabZ
fabI
fabB
fabG
fabZ
fabI
fabB
fabG
fabZ
fabI
fabB
fabG
fabZ
fabB
fabB
fabG
fabZ
fabI
Acetyl-CoA
Palmitic acid
Palmitic acid
Palmitic acid
Hydrogen
carbonate
Adenosine
triphosphate
Adenosine
diphosphate
Phosphate
Hydrogen Ion
Malonyl-CoA
Coenzyme A
Hydrogen Ion
Acetyl-CoA
Carbon dioxide
Coenzyme A
Hydrogen Ion
NADPH
NADP
Water
Hydrogen Ion
NADH
NAD
Hydrogen Ion
Carbon dioxide
Hydrogen Ion
NADPH
NADP
Water
Hydrogen Ion
NADH
NAD
Hydrogen Ion
Carbon dioxide
Hydrogen Ion
NADPH
NADP
Water
Hydrogen Ion
NADH
NAD
Hydrogen Ion
Carbon dioxide
Hydrogen Ion
NADPH
NADP
Water
Hydrogen Ion
NADH
NAD
Carbon dioxide
Hydrogen Ion
NADPH
NADP
Water
Hydrogen Ion
NADH
NAD
Water
Hydrogen Ion
Dodecanoic acid
Hydrogen Ion
Carbon dioxide
Hydrogen Ion
NADPH
NADP
Water
Hydrogen Ion
NADH
NAD
Hydrogen Ion
Carbon dioxide
Hydrogen Ion
NADPH
NADP
Water
Hydrogen Ion
NADH
NAD
Water
Hydrogen Ion
Octanoyl-
[acyl-carrier
protein]
a holo-[acyl-
carrier
protein]
a malonyl-[acp]
acetoacetyl-
[acp]
(R)-3-
hydroxybutanoyl-
[acp]
crotonyl-[acp]
butyryl-[acp]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
hexanoyl- [acp]
(R)-3-
hydroxyhexanoyl-
[acp]
trans
hex-2-enoyl-
[acp]
hexanoyl-
[acyl- carrier-
protein]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
octanoyl- [acp]
(R)-3-
hydroxyoctanoyl-
[acp]
trans
oct-2-enoyl-
[acp]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
decanoyl- [acp]
an (R)-3-
hydroxydecanoyl-
[acp]
a trans-Δ2-
decenoyl- [acp]
decanoyl-[acp]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
dodecanoyl-
[acp]
(R)-3-
hydroxydodecanoyl-
[acp]
trans dodec-2-
enoyl-[acp]
dodecanoyl-
[acp]
a holo-[acyl-
carrier
protein]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
myristoyl-
[acp]
(3R)-3-
hydroxymyristoyl-
[acp]
trans
tetradec-2-
enoyl-[acp]
myristoyl-[acp]
a malonyl-[acp]
a holo-[acyl-
carrier
protein]
3-oxo-
palmitoyl-
[acp]
(R)-3-
hydroxypalmitoyl-
[acp]
trans
hexadecenoyl-
[acp]
palmitoyl-[acp]
a holo-[acyl-
carrier
protein]
Glycolysis and
Pyruvate
Dehydrogenase
Lipoic Acid
Metabolism