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Glucuronide
carrier protein
Membrane-
associated
protein UidC
L-galactonate
transporter
2-keto-3-
deoxygluconate
permease
Hexuronate
transporter
High-affinity
gluconate
transporter
Uronate
isomerase
D-mannonate
oxidoreductase
Mannonate
dehydratase
Altronate
hydrolase
Altronate
oxidoreductase
2-dehydro-3-
deoxygluconokinase
KHG/KDPG
aldolase
Putative
L-galactonate
oxidoreductase
Beta-
glucuronidase
D-
Glyceraldehyde
3-phosphate
Pyruvic acid
Bilirubin
diglucuronide
Bilirubin
diglucuronide
H
+
H
+
Bilirubin
diglucuronide
aldehydo-L-
galactonate
aldehydo-L-
galactonate
H
+
H
+
2-Keto-3-
deoxy-D-
gluconic acid
2-Keto-3-
deoxy-D-
gluconic acid
H
+
H
+
H
+
H
+
aldehydo-D-
galacturonate
aldehydo-D-
galacturonate
D-fructuronate
D-fructuronate
H
+
H
+
D-
glucopyranuronate
aldehydo-D-
glucuronate
NADH
H
+
NAD
D-mannonate
H
2
O
D-Altronate
H
2
O
D-tagaturonate
NADH
H
+
NAD
ATP
H
+
2-Keto-3-
deoxy-6-
phosphogluconic
acid
ADP
NAD
NADH
H
+
H
2
O
Benzyl alcohol
Zinc (II) ion
Glycolysis and
Pyruvate
Dehydrogenase
Glycolysis and
Pyruvate
Dehydrogenase
uidB
uidC
yjjL
kdgT
exuT
gntP
uxaC
uxuB
uxuA
uxaA
uxaB
kdgK
eda
yjjN
uidA
D-
Glyceraldehyde
3-phosphate
Pyruvic acid
Bilirubin
diglucuronide
Bilirubin
diglucuronide
Hydrogen Ion
Hydrogen Ion
Bilirubin
diglucuronide
aldehydo-L-
galactonate
aldehydo-L-
galactonate
Hydrogen Ion
Hydrogen Ion
2-Keto-3-
deoxy-D-
gluconic acid
2-Keto-3-
deoxy-D-
gluconic acid
Hydrogen Ion
Hydrogen Ion
Hydrogen Ion
Hydrogen Ion
aldehydo-D-
galacturonate
aldehydo-D-
galacturonate
D-fructuronate
D-fructuronate
Hydrogen Ion
Hydrogen Ion
D-
glucopyranuronate
aldehydo-D-
glucuronate
NADH
Hydrogen Ion
NAD
D-mannonate
Water
D-Altronate
Water
D-tagaturonate
NADH
Hydrogen Ion
NAD
Adenosine
triphosphate
Hydrogen Ion
2-Keto-3-
deoxy-6-
phosphogluconic
acid
Adenosine
diphosphate
NAD
NADH
Hydrogen Ion
Water
Benzyl alcohol
Glycolysis and
Pyruvate
Dehydrogenase
Glycolysis and
Pyruvate
Dehydrogenase