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S- adenosylmethionine decarboxylase proenzyme Spermidine synthase 5'- methylthioadenosine/S- adenosylhomocysteine nucleosidase Spermidine N(1)- acetyltransferase S- adenosylmethionine synthase D-methionine transport system permease protein metI D-methionine- binding lipoprotein metQ D-methionine transport system permease protein metI D-methionine- binding lipoprotein metQ Methionine import ATP-binding protein MetN L-Methionine S- Adenosylmethionine H+ CO2 S- Adenosylmethioninamine Putrescine Spermidine H+ 5'-S-methyl- 5'- thioadenosine H2O 5- Methylthioribose Adenine Acetyl-CoA N8- Acetylspermidine CoA H+ H2O ATP Pi PPi L-Methionine ATP H2O ADP Pi H+ L-Methionine ATP H2O ADP PPi H+ Pyruvic acid Magnesium Methionine import ATP-binding protein MetN Methionine Biosynthesis
speD speE mtn speG metK metI metQ metI metQ metN L-Methionine S- Adenosylmethionine Hydrogen Ion Carbon dioxide S- Adenosylmethioninamine Putrescine Spermidine Hydrogen Ion 5'-S-methyl- 5'- thioadenosine Water 5- Methylthioribose Adenine Acetyl-CoA N8- Acetylspermidine Coenzyme A Hydrogen Ion Water Adenosine triphosphate Phosphate Pyrophosphate L-Methionine Adenosine triphosphate Water Adenosine diphosphate Phosphate Hydrogen Ion L-Methionine Adenosine triphosphate Water Adenosine diphosphate Pyrophosphate Hydrogen Ion metN Methionine Biosynthesis