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Sodium/glutamate symport carrier protein Proton glutamate symport protein Glutamyl-tRNA synthetase Glutamyl-tRNA reductase Glutamate-1- semialdehyde 2,1-aminomutase Delta- aminolevulinic acid dehydratase Porphobilinogen deaminase Uroporphyrinogen- III synthase Uroporphyrinogen decarboxylase Uroporphyrinogen decarboxylase Coproporphyrinogen- III oxidase, aerobic Oxygen- independent coproporphyrinogen- III oxidase Protoheme IX farnesyltransferase Catalase HPII Siroheme synthase Siroheme synthase Siroheme synthase Siroheme synthase Protoporphyrinogen oxidase Siroheme synthase Ferrochelatase Protoporphyrinogen oxidase Glutamate/aspartate transport ATP-binding protein gltL Glutamate/aspartate transport system permease protein gltK Glutamate/aspartate transport system permease protein gltJ Glutamate/aspartate periplasmic- binding protein L-Glutamic acid Siroheme Heme D ferroheme b Heme O L-Glutamic acid Na+ Na+ H+ H+ L-Glutamic acid H+ ATP AMP PPi NADPH NADP (S)-4-amino- 5- oxopentanoate 5- Aminolevulinic acid H+ H2O Porphobilinogen H2O Ammonium Hydroxymethylbilane H2O Uroporphyrinogen III Uroporphyrinogen I H2O H+ CO2 Coproporphyrinogen III Hydrogen Ion CO2 Coproporphyrinogen I H+ O2 H2O CO2 Protoporphyrinogen IX S- Adenosylmethionine 5'- Deoxyadenosine L-Methionine CO2 Protoporphyrinogen IX H2O Farnesyl pyrophosphate PPi H2O2 S- Adenosylmethionine H+ S- Adenosylhomocysteine Precorrin-1 S- Adenosylmethionine