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2- isopropylmalate synthase 3- isopropylmalate dehydratase large subunit 3- isopropylmalate dehydratase small subunit 3- isopropylmalate dehydratase large subunit 3- isopropylmalate dehydratase small subunit 3- isopropylmalate dehydrogenase D-malate dehydrogenase [decarboxylating] Branched- chain-amino- acid aminotransferase Aromatic- amino-acid aminotransferase 3-Methyl-2- oxovaleric acid H2O Acetyl-CoA CoA H+ 2- Isopropylmalic acid H2O Isopropylmaleate H2O 3- Isopropylmalate NAD NADH H+ 2-Isopropyl- 3- oxosuccinate H+ CO2 Ketoleucine L-Glutamic acid Oxoglutaric acid L-Leucine Isoleucine Biosynthesis
leuA leuC leuD leuC leuD leuB dmlA ilvE tyrB 3-Methyl-2- oxovaleric acid Water Acetyl-CoA Coenzyme A Hydrogen Ion 2- Isopropylmalic acid Water Isopropylmaleate Water 3- Isopropylmalate NAD NADH Hydrogen Ion 2-Isopropyl- 3- oxosuccinate Hydrogen Ion Carbon dioxide Ketoleucine L-Glutamic acid Oxoglutaric acid L-Leucine Isoleucine Biosynthesis
leuA leuC leuD leuC leuD leuB dmlA ilvE tyrB 3M2Oxva H2O Ac-CoA CoA H+ 2-Isopa H2O Isoprop H2O 3Isopr NAD NADH H+ 2ip3o H+ CO2 Ketoleu Glu AKG Leu PW000818