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Bifunctional
polymyxin
resistance
protein ArnA
UDP-4-amino-
4-deoxy-L-
arabinose--
oxoglutarate
aminotransferase
Bifunctional
polymyxin
resistance
protein ArnA
Undecaprenyl-
phosphate
4-deoxy-4-
formamido-L-
arabinose
transferase
Undecaprenyl
phosphate-
alpha-4-
amino-4-
deoxy-L-
arabinose
arabinosyl
transferase
Uridine
diphosphate
glucuronic acid
NAD
CO
2
NADH
UDP-β-L- threo-
pentapyranos-
4-ulose
L-Glutamic acid
Oxoglutaric
acid
UDP-4-amino-
4-deoxy-β-L-
arabinopyranose
10-
Formyltetrahydrofolate
UDP-4-deoxy-
4-formamido-
β-L-
arabinopyranose
H
+
Tetrahydrofolate
di- trans,octa-
cis-
undecaprenyl
phosphate
UDP
4-deoxy-4-
formamido-α- L-
arabinopyranosyl
ditrans,octacis-
undecaprenyl
phosphate
H
2
O
Formic acid
4-Amino-4-
deoxy-α-L-
arabinopyranosyl
di- trans,octa-
cis-
undecaprenyl
phosphate
(KDO)2-lipid A
di- trans,octa-
cis-
undecaprenyl
diphosphate
L-Ara4N-
modified
KDO2-Lipid A
arnA
arnB
arnA
arnC
arnT
Uridine
diphosphate
glucuronic acid
NAD
Carbon dioxide
NADH
UDP-β-L- threo-
pentapyranos-
4-ulose
L-Glutamic acid
Oxoglutaric
acid
UDP-4-amino-
4-deoxy-β-L-
arabinopyranose
10-
Formyltetrahydrofolate
UDP-4-deoxy-
4-formamido-
β-L-
arabinopyranose
Hydrogen Ion
Tetrahydrofolate
di- trans,octa-
cis-
undecaprenyl
phosphate
UDP
4-deoxy-4-
formamido-α- L-
arabinopyranosyl
ditrans,octacis-
undecaprenyl
phosphate
Water
Formic acid
4-Amino-4-
deoxy-α-L-
arabinopyranosyl
di- trans,octa-
cis-
undecaprenyl
phosphate
(KDO)2-lipid A
di- trans,octa-
cis-
undecaprenyl
diphosphate
L-Ara4N-
modified
KDO2-Lipid A