PathWhiz

Pathway Description

Ethanolamine Metabolism

Escherichia coli

Metabolic Pathway

Ethanolamine, in E. coli, is produced through phospholipid biosynthesis. Once in the cytosol it can be used to produce acetaldehyde by reacting with ethanolamine ammonia-lyase resulting in the release of ammonium and acetaldehyde.

References

Ethanolamine Metabolism References

Chang GW, Chang JT: Evidence for the B12-dependent enzyme ethanolamine deaminase in Salmonella. Nature. 1975 Mar 13;254(5496):150-1.

Pubmed: 1090845

Jones PW, Turner JM: Interrelationships between the enzymes of ethanolamine metabolism in Escherichia coli. J Gen Microbiol. 1984 Feb;130(2):299-308. doi: 10.1099/00221287-130-2-299.

Pubmed: 6374020

Jones PW, Turner JM: A model for the common control of enzymes of ethanolamine catabolism in Escherichia coli. J Gen Microbiol. 1984 Apr;130(4):849-60. doi: 10.1099/00221287-130-4-849.

Pubmed: 6376700

Penrod JT, Roth JR: Conserving a volatile metabolite: a role for carboxysome-like organelles in Salmonella enterica. J Bacteriol. 2006 Apr;188(8):2865-74. doi: 10.1128/JB.188.8.2865-2874.2006.

Pubmed: 16585748

Scarlett FA, Turner JM: Microbial metabolism of amino alcohols. Ethanolamine catabolism mediated by coenzyme B12-dependent ethanolamine ammonia-lyase in Escherichia coli and Klebsiella aerogenes. J Gen Microbiol. 1976 Jul;95(1):173-6. doi: 10.1099/00221287-95-1-173.

Pubmed: 784902

Highlighted elements will appear in red.

Highlight Compounds

	Acetaldehyde
	Ammonium
	Ethanolamine

Highlight Proteins

	Ethanolamine ammonia-lyase heavy chain
	Ethanolamine ammonia-lyase light chain

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