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Unknown Unknown 5- aminolevulinate synthase, nonspecific, mitochondrial Delta- aminolevulinic acid dehydratase Porphobilinogen deaminase Uroporphyrinogen- III synthase Uroporphyrinogen decarboxylase Uroporphyrinogen decarboxylase Coproporphyrinogen- III oxidase, mitochondrial Ferritin, mitochondrial Ferrochelatase, mitochondrial Protoheme IX farnesyltransferase, mitochondrial Cytochrome c oxidase assembly protein COX15 homolog Heme oxygenase 1 Biliverdin reductase A UDP- glucuronosyltransferase 2B11 Beta- glucuronidase Protoporphyrinogen oxidase Glycine Coproporphyrinogen III Coproporphyrinogen III Protoporphyrin IX Protoporphyrin IX Heme Heme Succinyl-CoA 5- Aminolevulinic acid CO2 Porphobilinogen H2O H2O Hydroxymethylbilane NH3 Uroporphyrinogen III H2O Uroporphyrin III Uroporphyrinogen I Coproporphyrinogen I CO2 Coproporphyrin I Uroporphyrin I CO2 Coproporphyrin III O2 H+ Protoporphyrinogen IX CO2 H2O Fe2+ H+ O2 Fe3+ H2O H+ Farnesyl pyrophosphate Heme O Heme A Heme O2 Biliverdin Fe2+ Carbon monoxide H2O NAD Bilirubin NADH Uridine diphosphate glucuronic acid Bilirubin diglucuronide Uridine 5'-diphosphate H2O Urobilinogen O2 H2O2 Pyridoxal 5'-phosphate Zinc 2Fe-2S Zinc FAD AH2 A Alcohol Glycine and Serine Metabolism Intracellular Space Mitochondria Outer mitochondrial membrane Inner mitochondrial membrane Microsome Microsome Lysosome