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cystathionine gamma-lyase N5- methyltetrahydropteroyltriglutamate- homocysteine methyltransferase cystathionine beta-lyase cystathionine beta-lyase subunit 2 cystathionine gamma-synthase thioredoxin reductase 1 thioredoxin reductase 2 cystathionine gamma-lyase cystathionine gamma-synthase methionine-- tRNA ligase MSM1 methionine-- tRNA ligase MES1 Selenomethionine H2O methylselenol NH3 2-Ketobutyric acid Selenohomocysteine 5- Methyltetrahydropteroyltri- L-glutamate Tetrahydropteroyltri- L-glutamate Selenocystathionine H2O NH3 Pyruvic acid Selenocysteine Acetylhomoserine Acetic acid NADPH H+ Methylselenic acid NADP H2O Se- Methylselenocysteine H2O NH3 Pyruvic acid O-succinyl-L- homoserine Succinic acid ATP AMP PPi Selenomethionyl- tRNA(Met) tRNA(Met)
CYS3 MET6 IRC7 STR3 STR2 TRR1 TRR2 CYS3 STR2 MSM1 MES1 Selenomethionine Water methylselenol Ammonia 2-Ketobutyric acid Selenohomocysteine 5- Methyltetrahydropteroyltri- L-glutamate Tetrahydropteroyltri- L-glutamate Selenocystathionine Water Ammonia Pyruvic acid Selenocysteine Acetylhomoserine Acetic acid NADPH Hydrogen Ion Methylselenic acid NADP Water Se- Methylselenocysteine Water Ammonia Pyruvic acid O-succinyl-L- homoserine Succinic acid Adenosine triphosphate Adenosine monophosphate Pyrophosphate Selenomethionyl- tRNA(Met) tRNA(Met)