Reaction995648
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041110 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001010 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000837 Cytoplasm/Stoichiometry/1.0
right: D-Lactic acid
right: N-Acetyl-D-Glucosamine 6-Phosphate
spontaneous: false
left: MurNAc-6-P
left: Water
name: MurNAc-6-P + Water → D-Lactic acid + N-Acetyl-D-Glucosamine 6-Phosphate
conversion direction: LEFT_TO_RIGHT

Reaction995649
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001858 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000141 Cytosol/Stoichiometry/1.0
right: N-Acetyl-D-glucosamine
right: Chitin
spontaneous: false
left: Chitin
left: Water
name: Chitin + Water → Chitin + N-Acetyl-D-glucosamine
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 388356
type: UnificationXref
id: 388356
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Compound/PW C000504/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactose 1-phosphate
stoichiometric coefficient: 1.0

3.2.1.14
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001925 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001858 Cytosol/Stoichiometry/1.0
right: Chitin
right: Chitobiose
spontaneous: false
EC number: 3.2.1.14
left: Chitin
left: Water
name: Chitin + Water → Chitin + Chitobiose
conversion direction: LEFT_TO_RIGHT

3.5.99.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000969 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C022608 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040941 Cytosol/Stoichiometry/1.0
right: Ammonium
right: β-D-fructofuranose 6-phosphate
spontaneous: false
EC number: 3.5.99.6
left: Glucosamine 6-phosphate
left: Water
name: Glucosamine 6-phosphate + Water → Ammonium + β-D-fructofuranose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

2.7.1.59
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000837 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000141 Cytosol/Stoichiometry/1.0
right: N-Acetyl-D-Glucosamine 6-Phosphate
right: Adenosine diphosphate
right: Hydrogen Ion
spontaneous: false
EC number: 2.7.1.59
left: N-Acetyl-D-glucosamine
left: Adenosine triphosphate
name: Adenosine triphosphate + N-Acetyl-D-glucosamine → Adenosine diphosphate + Hydrogen Ion + N-Acetyl-D-Glucosamine 6-Phosphate
conversion direction: LEFT_TO_RIGHT

3.2.1.52
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001925 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000141 Cytosol/Stoichiometry/2.0
right: N-Acetyl-D-glucosamine
spontaneous: false
EC number: 3.2.1.52
left: Chitobiose
left: Water
name: Chitobiose + Water → 2 N-Acetyl-D-glucosamine
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 16500
type: UnificationXref
id: 16500
db: PubChem-compound

Compound/PW C042904/Stoichiometry/1.0
type: Stoichiometry
physical entity: GDP-4-dehydro-6-deoxy-α-D-mannose
stoichiometric coefficient: 1.0

Glucose-specific phosphotransferase enzyme IIA component
type: ProteinReference
xref: Reference/UniProt P69783
organism: Escherichia coli UMN026

N-acetylglucosamine PTS permease
type: Complex
component stoichiometry: Protein/28268 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Unknown

Compound/PW C041033/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-glucose-1-phosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0003362
type: UnificationXref
id: HMDB0003362
db: HMDB

Reference/HMDB HMDB0001062
type: UnificationXref
id: HMDB0001062
db: HMDB

Compound/PW C042903/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Mannose 1-phosphate
stoichiometric coefficient: 1.0

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Escherichia coli UMN026
type: BioSource
xref: Reference/TAXONOMY 585056

3.5.1.25
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000969 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000837 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000029 Cytosol/Stoichiometry/1.0
right: Acetic acid
right: Glucosamine 6-phosphate
spontaneous: false
EC number: 3.5.1.25
left: N-Acetyl-D-Glucosamine 6-Phosphate
left: Water
name: N-Acetyl-D-Glucosamine 6-Phosphate + Water → Acetic acid + Glucosamine 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00446
type: UnificationXref
id: C00446
db: KEGG Compound

α-D-glucose-1-phosphate
type: SmallMolecule
entity reference: α-D-glucose-1-phosphate

Compound/PW C042905/Stoichiometry/1.0
type: Stoichiometry
physical entity: GDP-β-L-fucose
stoichiometric coefficient: 1.0

Starch and Sucrose Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway466835
pathway component: SubPathwayInteraction466835
xref: Reference/SMPDB SMP0000958
xref: Reference/PathWhiz PW000941
name: SubPathway

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

N-Acetyl-D-Glucosamine 6-Phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15784
xref: Reference/ChemSpider 389821
xref: Reference/BioCyc N-ACETYL-D-GLUCOSAMINE-6-P
xref: Reference/HMDB HMDB0001062
xref: Reference/KEGG Compound C00357
xref: Reference/CAS 102029-88-9
xref: Reference/PubChem-compound 440996
chemical formula: C8H16NO9P
molecular weight: 301.05627
structure: ChemicalStructure/PW C000837

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Chitobiose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003556
xref: Reference/ChemSpider 17216232
xref: Reference/CAS 577-76-4
xref: Reference/PubChem-compound 22833609
xref: Reference/KEGG Compound C01674
xref: Reference/BioCyc CHITOBIOSE
chemical formula: C15H26N2O12
molecular weight: 426.14856
structure: ChemicalStructure/PW C001925

Reference/KEGG Compound C14830
type: UnificationXref
id: C14830
db: KEGG Compound

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

α-D-glucose-1-phosphate
type: SmallMoleculeReference
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C041033

ReactionCoupledTransport11876
type: TransportWithBiochemicalReaction
participant stoichiometry: Protein/28268 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040952 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040951 Inner Membrane/Stoichiometry/1.0
right: Unknown
right: α-D-Mannose 6-phosphate
spontaneous: false
left: α-D-mannose
left: Unknown
name: HPr - phosphorylated + α-D-mannose → HPr + α-D-Mannose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 43896
type: UnificationXref
id: CHEBI:43896
db: ChEBI

ChemicalStructure/PW C042663
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 5743
type: UnificationXref
id: 5743
db: ChemSpider

Reference/BioCyc D-LACTATE
type: UnificationXref
id: D-LACTATE
db: BioCyc

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Compound/PW C000837 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-D-Glucosamine 6-Phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
type: UnificationXref
id: ALPHA-GLUCOSE-16-BISPHOSPHATE
db: BioCyc

Reference/ChemSpider 17216232
type: UnificationXref
id: 17216232
db: ChemSpider

Glucosamine 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Glucosamine 6-phosphate

ChemicalStructure/PW C001083
type: ChemicalStructure
structure format: SMILES

MurNAc-6-P
type: SmallMolecule
cellular location: Inner Membrane
entity reference: MurNAc-6-P

SubPathwayInteraction466835
type: Interaction
name: SubPathwayReaction
name: SubPathway466835Reaction
participant: ADP-glucose

Reference/PubChem-compound 53477679
type: UnificationXref
id: 53477679
db: PubChem-compound

Compound/PW C001851 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose
stoichiometric coefficient: 1.0

Reference/CAS 133-89-1
type: UnificationXref
id: 133-89-1
db: CAS

N-acetylmuramic acid PTS permease
type: Complex
cellular location: Inner Membrane
component: Unknown
component: Glucose-specific phosphotransferase enzyme IIA component

Reference/PubChem-compound 439174
type: UnificationXref
id: 439174
db: PubChem-compound

Reference/KEGG Compound C00461
type: UnificationXref
id: C00461
db: KEGG Compound

ChemicalStructure/PW C041109
type: ChemicalStructure
structure format: SMILES

Compound/PW C001083 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/CAS 10326-41-7
type: UnificationXref
id: 10326-41-7
db: CAS

Reference/KEGG Compound C01674
type: UnificationXref
id: C01674
db: KEGG Compound

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

ReactionCoupledTransportCatalysis11938
type: Catalysis
controller: mannose PTS permease
controlled: ReactionCoupledTransport11876
control type: ACTIVATION

ChemicalStructure/PW C041110
type: ChemicalStructure
structure format: SMILES
structure data: C[C@@H](O[C@H]1[C@H](O)[C@@H](COP([O-])([O-])=O)O[C@@H](O)[C@@H]1NC(C)=O)C([O-])=O

UDP-galactose
type: SmallMoleculeReference
chemical formula: C15H22N2Na2O17P2
molecular weight: 610.0189
structure: ChemicalStructure/PW C042663

Reference/ChEBI CHEBI 17029
type: UnificationXref
id: CHEBI:17029
db: ChEBI

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Galactose 1-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 110443
xref: Reference/KEGG Compound C00446
xref: Reference/ChEBI CHEBI 17973
xref: Reference/PubChem-compound 123912
xref: Reference/CAS 2255-14-3
xref: Reference/HMDB HMDB0000645
xref: Reference/BioCyc GALACTOSE-1P
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C000504

ADP-glucose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15751
xref: Reference/HMDB HMDB0006557
xref: Reference/CAS 2140-58-1
xref: Reference/PubChem-compound 16500
xref: Reference/BioCyc ADP-D-GLUCOSE
xref: Reference/ChemSpider 15642
xref: Reference/KEGG Compound C00498
chemical formula: C16H25N5O15P2
molecular weight: 589.0822
structure: ChemicalStructure/PW C002809

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Guanosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15996
xref: Reference/ChemSpider 6569
xref: Reference/KEGG Compound C00044
xref: Reference/PubChem-compound 6830
xref: Reference/HMDB HMDB0001273
xref: Reference/CAS 86-01-1
xref: Reference/BioCyc GTP
chemical formula: C10H16N5O14P3
molecular weight: 522.99066
structure: ChemicalStructure/PW C000986

Reference/ChemSpider 388319
type: UnificationXref
id: 388319
db: ChemSpider

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/KEGG Compound C00352
type: UnificationXref
id: C00352
db: KEGG Compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/KEGG Compound C00357
type: UnificationXref
id: C00357
db: KEGG Compound

Compound/PW C000170 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

ReactionCoupledTransportCatalysis11931
type: Catalysis
controller: glucose PTS permease
controlled: ReactionCoupledTransport11869
control type: ACTIVATION

Chitin
type: SmallMolecule
cellular location: Cytosol
entity reference: Chitin

Reference/HMDB HMDB0006557
type: UnificationXref
id: HMDB0006557
db: HMDB

Reference/CAS 3616-42-0
type: UnificationXref
id: 3616-42-0
db: CAS

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

ReactionCoupledTransport11869
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C001851 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/28268 Inner Membrane/Stoichiometry/1.0
right: Unknown
spontaneous: false
left: Unknown
left: α-D-Glucose
name: HPr - phosphorylated + α-D-Glucose → HPr
conversion direction: LEFT_TO_RIGHT

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

MurNAc
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 7212
chemical formula: C11H18NO8
molecular weight: 292.1038
structure: ChemicalStructure/PW C041109

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

α-D-Glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003345
xref: Reference/ChemSpider 71358
xref: Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
xref: Reference/PubChem-compound 79025
xref: Reference/ChEBI CHEBI 17925
xref: Reference/CAS 492-62-6
xref: Reference/KEGG Compound C00267
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C001851

MurNAc-6-P
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58721
chemical formula: C11H17NO11P
molecular weight: 370.05557
structure: ChemicalStructure/PW C041110

Chitobiose
type: SmallMolecule
cellular location: Cytosol
entity reference: Chitobiose

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

Protein/28268 Cytosol/Stoichiometry/6.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 6.0

Reference/KEGG Compound C00498
type: UnificationXref
id: C00498
db: KEGG Compound

ChemicalStructure/PW C000901
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00256
type: UnificationXref
id: C00256
db: KEGG Compound

Glucosamine 6-phosphate
type: SmallMoleculeReference
xref: Reference/CAS 3616-42-0
xref: Reference/ChemSpider 388356
xref: Reference/ChEBI CHEBI 15873
xref: Reference/KEGG Compound C00352
xref: Reference/BioCyc D-GLUCOSAMINE-6-P
xref: Reference/PubChem-compound 439217
xref: Reference/HMDB HMDB0001254
chemical formula: C6H14NO8P
molecular weight: 259.04572
structure: ChemicalStructure/PW C000969

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/KEGG Compound C00140
type: UnificationXref
id: C00140
db: KEGG Compound

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Reference/BioCyc D-GLUCOSAMINE-6-P
type: UnificationXref
id: D-GLUCOSAMINE-6-P
db: BioCyc

Compound/PW C000837 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-D-Glucosamine 6-Phosphate
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/KEGG Compound C00029
type: UnificationXref
id: C00029
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Compound/PW C001925 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chitobiose
stoichiometric coefficient: 1.0

Galactose 1-phosphate
type: SmallMolecule
entity reference: Galactose 1-phosphate

Reference/KEGG Compound C00267
type: UnificationXref
id: C00267
db: KEGG Compound

Guanosine triphosphate
type: SmallMolecule
entity reference: Guanosine triphosphate

Reference/BioCyc ACET
type: UnificationXref
id: ACET
db: BioCyc

Compound/PW C000193/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate glucose
stoichiometric coefficient: 1.0

Compound/PW C000901/Stoichiometry/1.0
type: Stoichiometry
physical entity: Guanosine diphosphate mannose
stoichiometric coefficient: 1.0

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/ChemSpider 15642
type: UnificationXref
id: 15642
db: ChemSpider

Reference/CAS 577-76-4
type: UnificationXref
id: 577-76-4
db: CAS

Reference/KEGG Compound C00033
type: UnificationXref
id: C00033
db: KEGG Compound

Water
type: SmallMolecule
entity reference: Water

Reference/PubChem-compound 123912
type: UnificationXref
id: 123912
db: PubChem-compound

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Compound/PW C001076/Stoichiometry/1.0
type: Stoichiometry
physical entity: GDP-4-Dehydro-6-L-deoxygalactose
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00044
type: UnificationXref
id: C00044
db: KEGG Compound

Reference/CAS 2140-58-1
type: UnificationXref
id: 2140-58-1
db: CAS

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Compound/PW C002809 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: ADP-glucose
stoichiometric coefficient: 1.0

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 389821
type: UnificationXref
id: 389821
db: ChemSpider

Protein/28268 Cytosol/Stoichiometry/4.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 4.0

Reference/ChemSpider 399508
type: UnificationXref
id: 399508
db: ChemSpider

Reference/PathWhiz PW451622
type: UnificationXref
id: PW451622
db: PathWhiz

ChemicalStructure/PW C000029
type: ChemicalStructure
structure format: SMILES
structure data: CC(O)=O

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Chitin
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17029
xref: Reference/ChemSpider 399508
xref: Reference/HMDB HMDB0003362
xref: Reference/CAS 1398-61-4
xref: Reference/KEGG Compound C00461
xref: Reference/PubChem-compound 21252321
xref: Reference/BioCyc 14-N-ACETYL-BETA-D-GLUCOSAMINYLN1
chemical formula: C24H41N3O16
molecular weight: 627.24866
structure: ChemicalStructure/PW C001858

Reference/ChEBI CHEBI 4170
type: UnificationXref
id: CHEBI:4170
db: ChEBI

ReactionCatalysis1013229
type: Catalysis
controller: glucose-1-phosphate adenylyltransferase
controlled: 2.7.7.27
control type: ACTIVATION

ReactionCatalysis1013228
type: Catalysis
controller: Unknown
controlled: 5.4.2.2
control type: ACTIVATION

Reference/ChemSpider 110443
type: UnificationXref
id: 110443
db: ChemSpider

ReactionCatalysis1013234
type: Catalysis
controller: Unknown
controlled: Reaction995697
control type: ACTIVATION

ReactionCatalysis1013233
type: Catalysis
controller: Unknown
controlled: Reaction995696
control type: ACTIVATION

ReactionCatalysis1013235
type: Catalysis
controller: Unknown
controlled: Reaction995698
control type: ACTIVATION

ReactionCatalysis1013230
type: Catalysis
controller: galactose-1-phosphate uridylyltransferase
controlled: Reaction995693
control type: ACTIVATION

Unknown
type: ProteinReference
organism: Escherichia coli UMN026

ADP-glucose
type: SmallMolecule
cellular location: Cytosol
entity reference: ADP-glucose
name: SubPathwayInput

ReactionCatalysis1013232
type: Catalysis
controller: Unknown
controlled: Reaction995695
control type: ACTIVATION

ReactionCatalysis1013231
type: Catalysis
controller: Unknown
controlled: 5.4.2.8
control type: ACTIVATION

Reference/PubChem-compound 53477726
type: UnificationXref
id: 53477726
db: PubChem-compound

Reference/CAS 492-62-6
type: UnificationXref
id: 492-62-6
db: CAS

Reference/BioCyc 14-N-ACETYL-BETA-D-GLUCOSAMINYLN1
type: UnificationXref
id: 14-N-ACETYL-BETA-D-GLUCOSAMINYLN1
db: BioCyc

Reference/SMPDB SMP0000958
type: UnificationXref
id: SMP0000958
db: SMPDB

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/HMDB HMDB0003556
type: UnificationXref
id: HMDB0003556
db: HMDB

Reference/ChEBI CHEBI 7212
type: UnificationXref
id: CHEBI:7212
db: ChEBI

Amino Sugar and Nucleotide Sugar Metabolism II
type: Pathway
pathway order: PathwayEnzymeReaction/6357095
pathway order: PathwayEnzymeReaction/6357083
pathway order: PathwayEnzymeReaction/6357094
pathway order: PathwayEnzymeReaction/6357082
pathway order: PathwayEnzymeReaction/6357093
pathway order: PathwayEnzymeReaction/6357081
pathway order: PathwayEnzymeReaction/6357092
pathway order: PathwayEnzymeReaction/6357080
pathway order: PathwayEnzymeReaction/6357091
pathway order: PathwaySubPathway/466835
pathway order: PathwayEnzymeReaction/6357090
pathway order: PathwayEnzymeReaction/6357101
pathway order: PathwayEnzymeReaction/6357089
pathway order: PathwayEnzymeReaction/6357100
pathway order: PathwayEnzymeReaction/6357088
pathway order: PathwayEnzymeReaction/6357099
pathway order: PathwayEnzymeReaction/6357087
pathway order: PathwayEnzymeReaction/6357098
pathway order: PathwayEnzymeReaction/6357086
pathway order: PathwayEnzymeReaction/6357097
pathway order: PathwayEnzymeReaction/6357096
pathway component: Reaction995648
pathway component: ReactionCoupledTransport11876
pathway component: Reaction995649
pathway component: ReactionCoupledTransportCatalysis14343
pathway component: 3.2.1.14
pathway component: 3.5.99.6
pathway component: 2.7.1.59
pathway component: 3.2.1.52
pathway component: ReactionCatalysis1013229
pathway component: ReactionCoupledTransportCatalysis11931
pathway component: ReactionCatalysis1013228
pathway component: ReactionCatalysis1013179
pathway component: ReactionCatalysis1013234
pathway component: ReactionCatalysis1013233
pathway component: ReactionCatalysis1013235
pathway component: ReactionCatalysis1013230
pathway component: ReactionCatalysis1013177
pathway component: ReactionCatalysis1013232
pathway component: ReactionCatalysis1013176
pathway component: ReactionCatalysis1013231
pathway component: ReactionCatalysis840561
pathway component: 3.5.1.25
pathway component: 5.3.1.8
pathway component: ReactionCoupledTransport11869
pathway component: Starch and Sucrose Metabolism
pathway component: Reaction995695
pathway component: Reaction995696
pathway component: Reaction995697
pathway component: Reaction995698
pathway component: 5.4.2.2
pathway component: 2.7.7.27
pathway component: 2.7.1.69
pathway component: ReactionCoupledTransportCatalysis14336
pathway component: Reaction995693
pathway component: 5.4.2.8
pathway component: 2.7.1.-
pathway component: ReactionCatalysis1013186
pathway component: ReactionCatalysis1013185
pathway component: ReactionCoupledTransportCatalysis11938
pathway component: ReactionCatalysis1013181
pathway component: ReactionCatalysis1013180
xref: Reference/PathWhiz PW451622
xref: Reference/SMPDB SMP0436325
organism: Escherichia coli UMN026

ChemicalStructure/PW C001010
type: ChemicalStructure
structure format: SMILES
structure data: C[C@H](O)C(O)=O

N-Acetyl-D-Glucosamine 6-Phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: N-Acetyl-D-Glucosamine 6-Phosphate

Reference/HMDB HMDB0000042
type: UnificationXref
id: HMDB0000042
db: HMDB

Compound/PW C000837 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-D-Glucosamine 6-Phosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001254
type: UnificationXref
id: HMDB0001254
db: HMDB

Reference/HMDB HMDB0000286
type: UnificationXref
id: HMDB0000286
db: HMDB

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

N-Acetyl-D-Glucosamine 6-Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: N-Acetyl-D-Glucosamine 6-Phosphate

N-Acetyl-D-glucosamine
type: SmallMolecule
cellular location: Inner Membrane
entity reference: N-Acetyl-D-glucosamine

Reference/PathWhiz PW000941
type: UnificationXref
id: PW000941
db: PathWhiz

ChemicalStructure/PW C040941
type: ChemicalStructure
structure format: SMILES
structure data: OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

ChemicalStructure/PW C040949
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis1013179
type: Catalysis
controller: Unknown
controlled: 2.7.1.59
control type: ACTIVATION

D-Lactic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: D-Lactic acid

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

ReactionCatalysis1013177
type: Catalysis
controller: glucosamine-6-phosphate deaminase
controlled: 3.5.99.6
control type: ACTIVATION

ReactionCatalysis1013176
type: Catalysis
controller: N-acetylglucosamine-6-phosphate deacetylase
controlled: 3.5.1.25
control type: ACTIVATION

Protein/28268 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 42111
type: UnificationXref
id: CHEBI:42111
db: ChEBI

α-D-Glucose 1-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: α-D-Glucose 1-phosphate

ChemicalStructure/PW C040952
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C040951
type: ChemicalStructure
structure format: SMILES

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/PubChem-compound 22833609
type: UnificationXref
id: 22833609
db: PubChem-compound

Reference/BioCyc GTP
type: UnificationXref
id: GTP
db: BioCyc

mannose PTS permease
type: Complex
component stoichiometry: Protein/28268 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Unknown

Reference/KEGG Compound C00092
type: UnificationXref
id: C00092
db: KEGG Compound

ChemicalStructure/PW C001076
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 71358
type: UnificationXref
id: 71358
db: ChemSpider

Reference/KEGG Compound C00096
type: UnificationXref
id: C00096
db: KEGG Compound

ReactionCatalysis1013186
type: Catalysis
controller: Unknown
controlled: Reaction995649
control type: ACTIVATION

ReactionCatalysis1013185
type: Catalysis
controller: N-acetylmuramic acid 6-phosphate etherase
controlled: Reaction995648
control type: ACTIVATION

Reference/CAS 2255-14-3
type: UnificationXref
id: 2255-14-3
db: CAS

Reference/HMDB HMDB0001391
type: UnificationXref
id: HMDB0001391
db: HMDB

ReactionCatalysis1013181
type: Catalysis
controller: Unknown
controlled: 3.2.1.14
control type: ACTIVATION

Reference/HMDB HMDB0001273
type: UnificationXref
id: HMDB0001273
db: HMDB

ReactionCatalysis1013180
type: Catalysis
controller: Unknown
controlled: 3.2.1.52
control type: ACTIVATION

Acetic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Acetic acid

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/CAS 56-73-5
type: UnificationXref
id: 56-73-5
db: CAS

ChemicalStructure/PW C042903
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C042904
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C042905
type: ChemicalStructure
structure format: SMILES

Glucose-specific phosphotransferase enzyme IIA component
type: Protein
cellular location: Inner Membrane
entity reference: Glucose-specific phosphotransferase enzyme IIA component

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Reference/HMDB HMDB0003345
type: UnificationXref
id: HMDB0003345
db: HMDB

Compound/PW C000986/Stoichiometry/1.0
type: Stoichiometry
physical entity: Guanosine triphosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 18396
type: UnificationXref
id: 18396
db: PubChem-compound

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

α-D-Mannose 6-phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: α-D-Mannose 6-phosphate

Ammonium
type: SmallMolecule
cellular location: Cytosol
entity reference: Ammonium

Reference/SMPDB SMP0436325
type: UnificationXref
id: SMP0436325
db: SMPDB

ChemicalStructure/PW C000193
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001163
type: UnificationXref
id: HMDB0001163
db: HMDB

N-Acetyl-D-Glucosamine 6-Phosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: N-Acetyl-D-Glucosamine 6-Phosphate

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

glucosamine-6-phosphate deaminase
type: Complex
component stoichiometry: Protein/28268 Cytosol/Stoichiometry/6.0
cellular location: Cytosol
component: Unknown

Reference/ChEBI CHEBI 57273
type: UnificationXref
id: CHEBI:57273
db: ChEBI

Compound/PW C040952 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-mannose
stoichiometric coefficient: 1.0

Reference/CAS 102029-88-9
type: UnificationXref
id: 102029-88-9
db: CAS

Compound/PW C022608 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 57634
type: UnificationXref
id: CHEBI:57634
db: ChEBI

Reference/ChEBI CHEBI 58601
type: UnificationXref
id: CHEBI:58601
db: ChEBI

MurNAc
type: SmallMolecule
cellular location: Inner Membrane
entity reference: MurNAc

2.7.1.69
type: TransportWithBiochemicalReaction
participant stoichiometry: Protein/28268 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000837 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000141 Inner Membrane/Stoichiometry/1.0
right: N-Acetyl-D-Glucosamine 6-Phosphate
right: Unknown
spontaneous: false
EC number: 2.7.1.69
left: N-Acetyl-D-glucosamine
left: Unknown
name: HPr - phosphorylated + N-Acetyl-D-glucosamine → HPr + N-Acetyl-D-Glucosamine 6-Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 58721
type: UnificationXref
id: CHEBI:58721
db: ChEBI

2.7.1.-
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C041109 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/28268 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041110 Inner Membrane/Stoichiometry/1.0
right: Unknown
right: MurNAc-6-P
spontaneous: false
EC number: 2.7.1.-
left: Unknown
left: MurNAc
name: HPr - phosphorylated + MurNAc → HPr + MurNAc-6-P
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc GDP-4-DEHYDRO-6-L-DEOXYGALACTOSE
type: UnificationXref
id: GDP-4-DEHYDRO-6-L-DEOXYGALACTOSE
db: BioCyc

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Acetic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15366
xref: Reference/BioCyc ACET
xref: Reference/CAS 64-19-7
xref: Reference/KEGG Compound C00033
xref: Reference/ChemSpider 171
xref: Reference/HMDB HMDB0000042
xref: Reference/PubChem-compound 176
chemical formula: C2H4O2
molecular weight: 60.02113
structure: ChemicalStructure/PW C000029

GDP-4-dehydro-6-deoxy-α-D-mannose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 57964
chemical formula: C16H21N5O15P2
molecular weight: 585.05206
structure: ChemicalStructure/PW C042904

α-D-Mannose 1-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58409
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C042903

GDP-β-L-fucose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 57273
chemical formula: C16H23N5O15P2
molecular weight: 587.0677
structure: ChemicalStructure/PW C042905

Reference/CAS 64-19-7
type: UnificationXref
id: 64-19-7
db: CAS

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/PubChem-compound 21252321
type: UnificationXref
id: 21252321
db: PubChem-compound

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

galactose-1-phosphate uridylyltransferase
type: Complex
component stoichiometry: Protein/28268/Stoichiometry/2.0
component: Unknown

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/BioCyc GALACTOSE-1P
type: UnificationXref
id: GALACTOSE-1P
db: BioCyc

D-Lactic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001311
xref: Reference/ChemSpider 55423
xref: Reference/BioCyc D-LACTATE
xref: Reference/CAS 10326-41-7
xref: Reference/KEGG Compound C00256
xref: Reference/PubChem-compound 61503
xref: Reference/ChEBI CHEBI 42111
chemical formula: C3H6O3
molecular weight: 90.03169
structure: ChemicalStructure/PW C001010

Water
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Water

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/BioCyc ALPHA-D-GALACTOSYL-13-BETA-D-GALACTOS
type: UnificationXref
id: ALPHA-D-GALACTOSYL-13-BETA-D-GALACTOS
db: BioCyc

Reference/BioCyc N-ACETYL-D-GLUCOSAMINE-6-P
type: UnificationXref
id: N-ACETYL-D-GLUCOSAMINE-6-P
db: BioCyc

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/ChEBI CHEBI 15820
type: UnificationXref
id: CHEBI:15820
db: ChEBI

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

α-D-Glucose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: α-D-Glucose

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/HMDB HMDB0001401
type: UnificationXref
id: HMDB0001401
db: HMDB

Compound/PW C042663/Stoichiometry/1.0
type: Stoichiometry
physical entity: UDP-galactose
stoichiometric coefficient: 1.0

Protein/28268 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Compound/PW C040941 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-fructofuranose 6-phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc CHITOBIOSE
type: UnificationXref
id: CHITOBIOSE
db: BioCyc

Protein/28268 Cytoplasm/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Compound/PW C041110 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: MurNAc-6-P
stoichiometric coefficient: 1.0

Reference/ChemSpider 55423
type: UnificationXref
id: 55423
db: ChemSpider

N-Acetyl-D-glucosamine
type: SmallMolecule
cellular location: Cytosol
entity reference: N-Acetyl-D-glucosamine

Pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Pyrophosphate

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/PubChem-compound 6830
type: UnificationXref
id: 6830
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

NADP
type: SmallMolecule
entity reference: NADP

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

N-Acetyl-D-glucosamine
type: SmallMoleculeReference
xref: Reference/BioCyc ALPHA-D-GALACTOSYL-13-BETA-D-GALACTOS
xref: Reference/ChEBI CHEBI 506227
xref: Reference/HMDB HMDB0000215
xref: Reference/KEGG Compound C00140
xref: Reference/ChemSpider 388319
xref: Reference/PubChem-compound 439174
xref: Reference/CAS 7512-17-6
chemical formula: C8H15NO6
molecular weight: 221.08994
structure: ChemicalStructure/PW C000141

Unknown
type: Protein
entity reference: Unknown

Compound/PW C000141 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-D-glucosamine
stoichiometric coefficient: 1.0

α-D-mannose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: α-D-mannose

α-D-Mannose 6-phosphate
type: SmallMolecule
entity reference: α-D-Mannose 6-phosphate

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

Compound/PW C000029 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetic acid
stoichiometric coefficient: 1.0

Uridine diphosphate glucose
type: SmallMoleculeReference
xref: Reference/BioCyc UDP-GLUCOSE
xref: Reference/KEGG Compound C00029
xref: Reference/PubChem-compound 53477679
xref: Reference/CAS 133-89-1
xref: Reference/HMDB HMDB0000286
chemical formula: C15H24N2O17P2
molecular weight: 566.055
structure: ChemicalStructure/PW C000193

Reference/BioCyc UDP-GLUCOSE
type: UnificationXref
id: UDP-GLUCOSE
db: BioCyc

Reference/HMDB HMDB0000215
type: UnificationXref
id: HMDB0000215
db: HMDB

Protein/28268/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Reference/CAS 1398-61-4
type: UnificationXref
id: 1398-61-4
db: CAS

glucose-1-phosphate adenylyltransferase
type: Complex
component stoichiometry: Protein/28268 Cytosol/Stoichiometry/4.0
cellular location: Cytosol
component: Unknown

Compound/PW C041110 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: MurNAc-6-P
stoichiometric coefficient: 1.0

Reference/BioCyc GDP-MANNOSE
type: UnificationXref
id: GDP-MANNOSE
db: BioCyc

β-D-fructofuranose 6-phosphate
type: SmallMolecule
entity reference: β-D-fructofuranose 6-phosphate

Reference/UniProt P69783
type: UnificationXref
id: P69783
db: UniProt

Compound/PW C040951 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Mannose 6-phosphate
stoichiometric coefficient: 1.0

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001311
type: UnificationXref
id: HMDB0001311
db: HMDB

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

ChemicalStructure/PW C000141
type: ChemicalStructure
structure format: SMILES

Compound/PW C040941/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-fructofuranose 6-phosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Compound/PW C040951/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Mannose 6-phosphate
stoichiometric coefficient: 1.0

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Unknown
type: Protein
cellular location: Inner Membrane
entity reference: Unknown

β-D-fructofuranose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 57634
chemical formula: C6H11O9P
molecular weight: 258.01517
structure: ChemicalStructure/PW C040941

Reference/ChEBI CHEBI 16955
type: UnificationXref
id: CHEBI:16955
db: ChEBI

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

N-acetylmuramic acid 6-phosphate etherase
type: Complex
component stoichiometry: Protein/28268 Cytoplasm/Stoichiometry/2.0
cellular location: Cytoplasm
component: Unknown

α-D-Glucose 1-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58601
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C040949

α-D-glucose-1-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: α-D-glucose-1-phosphate

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Uridine diphosphate glucose
type: SmallMolecule
entity reference: Uridine diphosphate glucose

Reference/PubChem-compound 5958
type: UnificationXref
id: 5958
db: PubChem-compound

Reference/ChemSpider 17372
type: UnificationXref
id: 17372
db: ChemSpider

Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/ChEBI CHEBI 15751
type: UnificationXref
id: CHEBI:15751
db: ChEBI

Reference/ChEBI CHEBI 15873
type: UnificationXref
id: CHEBI:15873
db: ChEBI

MurNAc-6-P
type: SmallMolecule
cellular location: Cytoplasm
entity reference: MurNAc-6-P

Reference/TAXONOMY 585056
type: UnificationXref
id: 585056
db: TAXONOMY

α-D-Mannose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 43896
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C040951

Reference/ChEBI CHEBI 15996
type: UnificationXref
id: CHEBI:15996
db: ChEBI

Reference/ChEBI CHEBI 57964
type: UnificationXref
id: CHEBI:57964
db: ChEBI

α-D-mannose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 28729
xref: Reference/HMDB HMDB0062170
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C040952

GDP-β-L-fucose
type: SmallMolecule
entity reference: GDP-β-L-fucose

GDP-4-dehydro-6-deoxy-α-D-mannose
type: SmallMolecule
entity reference: GDP-4-dehydro-6-deoxy-α-D-mannose

Reference/PubChem-compound 440996
type: UnificationXref
id: 440996
db: PubChem-compound

α-D-Mannose 1-phosphate
type: SmallMolecule
entity reference: α-D-Mannose 1-phosphate

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 17925
type: UnificationXref
id: CHEBI:17925
db: ChEBI

Reference/ChEBI CHEBI 58409
type: UnificationXref
id: CHEBI:58409
db: ChEBI

Reference/HMDB HMDB0062170
type: UnificationXref
id: HMDB0062170
db: HMDB

ChemicalStructure/PW C000969
type: ChemicalStructure
structure format: SMILES

Compound/PW C000141 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: N-Acetyl-D-glucosamine
stoichiometric coefficient: 2.0

glucose PTS permease
type: Complex
component stoichiometry: Protein/28268 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Unknown
component: Glucose-specific phosphotransferase enzyme IIA component

Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00092
xref: Reference/BioCyc GLC-6-P
xref: Reference/HMDB HMDB0001401
xref: Reference/PubChem-compound 5958
xref: Reference/ChemSpider 5743
xref: Reference/CAS 56-73-5
xref: Reference/ChEBI CHEBI 4170
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001083

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

ReactionCatalysis840561
type: Catalysis
controller: Unknown
controlled: 5.3.1.8
control type: ACTIVATION

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Reference/ChEBI CHEBI 15784
type: UnificationXref
id: CHEBI:15784
db: ChEBI

Compound/PW C041033 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-glucose-1-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

β-D-fructofuranose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: β-D-fructofuranose 6-phosphate

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Reference/PubChem-compound 439217
type: UnificationXref
id: 439217
db: PubChem-compound

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

Reference/ChEBI CHEBI 17973
type: UnificationXref
id: CHEBI:17973
db: ChEBI

N-acetylglucosamine-6-phosphate deacetylase
type: Complex
component stoichiometry: Protein/28268 Cytosol/Stoichiometry/4.0
cellular location: Cytosol
component: Unknown

UDP-galactose
type: SmallMolecule
entity reference: UDP-galactose

Reaction995695
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000986/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000901/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042903/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Guanosine diphosphate mannose
right: Pyrophosphate
spontaneous: false
left: Hydrogen Ion
left: α-D-Mannose 1-phosphate
left: Guanosine triphosphate
name: Guanosine triphosphate + Hydrogen Ion + α-D-Mannose 1-phosphate → Guanosine diphosphate mannose + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reaction995696
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000901/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042904/Stoichiometry/1.0
right: Water
right: GDP-4-dehydro-6-deoxy-α-D-mannose
spontaneous: false
left: Guanosine diphosphate mannose
name: Guanosine diphosphate mannose → GDP-4-dehydro-6-deoxy-α-D-mannose + Water
conversion direction: LEFT_TO_RIGHT

Reaction995697
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042905/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042904/Stoichiometry/1.0
right: NADP
right: GDP-β-L-fucose
spontaneous: false
left: Hydrogen Ion
left: GDP-4-dehydro-6-deoxy-α-D-mannose
left: NADPH
name: GDP-4-dehydro-6-deoxy-α-D-mannose + Hydrogen Ion + NADPH → GDP-β-L-fucose + NADP
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 28729
type: UnificationXref
id: CHEBI:28729
db: ChEBI

Reaction995698
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001076/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000901/Stoichiometry/1.0
right: GDP-4-Dehydro-6-L-deoxygalactose
spontaneous: false
left: Guanosine diphosphate mannose
name: Guanosine diphosphate mannose → GDP-4-Dehydro-6-L-deoxygalactose
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000837
type: ChemicalStructure
structure format: SMILES

5.4.2.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001083 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040949 Cytosol/Stoichiometry/1.0
right: α-D-Glucose 1-phosphate
spontaneous: false
EC number: 5.4.2.2
left: Glucose 6-phosphate
name: Glucose 6-phosphate → α-D-Glucose 1-phosphate
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C001925
type: ChemicalStructure
structure format: SMILES

2.7.7.27
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041033 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002809 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytosol/Stoichiometry/1.0
right: ADP-glucose
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.27
left: α-D-glucose-1-phosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + α-D-glucose-1-phosphate → ADP-glucose + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reaction995693
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042663/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000504/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041033/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000193/Stoichiometry/1.0
right: Uridine diphosphate glucose
right: Galactose 1-phosphate
spontaneous: false
left: α-D-glucose-1-phosphate
left: UDP-galactose
name: UDP-galactose + α-D-glucose-1-phosphate → Galactose 1-phosphate + Uridine diphosphate glucose
conversion direction: LEFT_TO_RIGHT

5.4.2.8
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040951/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042903/Stoichiometry/1.0
right: α-D-Mannose 1-phosphate
spontaneous: false
EC number: 5.4.2.8
left: α-D-Mannose 6-phosphate
name: α-D-Mannose 6-phosphate ↔ α-D-Mannose 1-phosphate
conversion direction: REVERSIBLE

Reference/ChEBI CHEBI 506227
type: UnificationXref
id: CHEBI:506227
db: ChEBI

Reference/BioCyc GLC-6-P
type: UnificationXref
id: GLC-6-P
db: BioCyc

GDP-4-Dehydro-6-L-deoxygalactose
type: SmallMoleculeReference
xref: Reference/KEGG Compound C14830
xref: Reference/BioCyc GDP-4-DEHYDRO-6-L-DEOXYGALACTOSE
xref: Reference/ChEBI CHEBI 16955
xref: Reference/HMDB HMDB0001391
xref: Reference/PubChem-compound 53477726
chemical formula: C16H23N5O15P2
molecular weight: 587.0666
structure: ChemicalStructure/PW C001076

GDP-4-Dehydro-6-L-deoxygalactose
type: SmallMolecule
entity reference: GDP-4-Dehydro-6-L-deoxygalactose

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15366
type: UnificationXref
id: CHEBI:15366
db: ChEBI

Guanosine diphosphate mannose
type: SmallMoleculeReference
xref: Reference/BioCyc GDP-MANNOSE
xref: Reference/CAS 3123-67-9
xref: Reference/KEGG Compound C00096
xref: Reference/PubChem-compound 18396
xref: Reference/ChemSpider 17372
xref: Reference/ChEBI CHEBI 15820
xref: Reference/HMDB HMDB0001163
chemical formula: C16H25N5O16P2
molecular weight: 605.07715
structure: ChemicalStructure/PW C000901

Glucose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Glucose 6-phosphate

ChemicalStructure/PW C001858
type: ChemicalStructure
structure format: SMILES

Compound/PW C000969 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucosamine 6-phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 171
type: UnificationXref
id: 171
db: ChemSpider

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

5.3.1.8
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040941/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040951/Stoichiometry/1.0
right: β-D-fructofuranose 6-phosphate
spontaneous: false
EC number: 5.3.1.8
left: α-D-Mannose 6-phosphate
name: α-D-Mannose 6-phosphate ↔ β-D-fructofuranose 6-phosphate
conversion direction: REVERSIBLE

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/ChemSpider 6569
type: UnificationXref
id: 6569
db: ChemSpider

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Reference/CAS 3123-67-9
type: UnificationXref
id: 3123-67-9
db: CAS

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 79025
type: UnificationXref
id: 79025
db: PubChem-compound

Reference/PubChem-compound 61503
type: UnificationXref
id: 61503
db: PubChem-compound

ReactionCoupledTransportCatalysis14343
type: Catalysis
controller: N-acetylmuramic acid PTS permease
controlled: 2.7.1.-
control type: ACTIVATION

ChemicalStructure/PW C002809
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

ChemicalStructure/PW C000986
type: ChemicalStructure
structure format: SMILES

Compound/PW C040949 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose 1-phosphate
stoichiometric coefficient: 1.0

Compound/PW C000141 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-D-glucosamine
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000504
type: ChemicalStructure
structure format: SMILES

Reference/CAS 86-01-1
type: UnificationXref
id: 86-01-1
db: CAS

Compound/PW C001858 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chitin
stoichiometric coefficient: 1.0

Compound/PW C001010 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Lactic acid
stoichiometric coefficient: 1.0

Guanosine diphosphate mannose
type: SmallMolecule
entity reference: Guanosine diphosphate mannose

ReactionCoupledTransportCatalysis14336
type: Catalysis
controller: N-acetylglucosamine PTS permease
controlled: 2.7.1.69
control type: ACTIVATION

Unknown
type: Protein
cellular location: Cytoplasm
entity reference: Unknown

Reference/PubChem-compound 176
type: UnificationXref
id: 176
db: PubChem-compound

ChemicalStructure/PW C001851
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000645
type: UnificationXref
id: HMDB0000645
db: HMDB

Compound/PW C041109 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: MurNAc
stoichiometric coefficient: 1.0

ChemicalStructure/PW C041033
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc ADP-D-GLUCOSE
type: UnificationXref
id: ADP-D-GLUCOSE
db: BioCyc

Reference/CAS 7512-17-6
type: UnificationXref
id: 7512-17-6
db: CAS