SMPDB

Showing 1541 - 1560 of 1576 proteins

Protein ID	Protein	Pathways
Unknown View in UniProt	Unknown	2-Amino-3-Carboxymuconate Semialdehyde Degradation 2-Aminoadipic 2-Oxoadipic Aciduria Amino Sugar Metabolism Angiotensin Metabolism Anti-inflammatory pathway Aspartate Metabolism Bacterial Sepsis Benazepril Action Pathway Canavan Disease Candesartan Action Pathway Captopril Action Pathway Cilazapril Action Pathway DOPA-Responsive Dystonia Enalapril Action Pathway Eprosartan Action Pathway Forasartan Action Pathway Fosinopril Action Pathway Glutaric Aciduria Type I Hyperlysinemia I, Familial Hyperlysinemia II or Saccharopinuria Hyperphenylalaninemia Due to 6-Pyruvoyltetrahydropterin Synthase Deficiency (ptps) Hyperphenylalaninemia Due to DHPR-Deficiency Hyperphenylalaninemia Due to Guanosine Triphosphate Cyclohydrolase Deficiency Hypoacetylaspartia Immunometabolism Pathway (Bacterial Activation) Immunometabolism Pathway (Viral Activation) Irbesartan Action Pathway Lisinopril Action Pathway Losartan Action Pathway Lysine Degradation Metabolism and Physiological Effects of Indoxyl Sulfate Moexipril Action Pathway Olmesartan Action Pathway Perindopril Action Pathway Pterine Biosynthesis Pyridoxine Dependency with Seizures Quinapril Action Pathway Ramipril Action Pathway Rescinnamine Action Pathway Saccharopinuria/Hyperlysinemia II Salla Disease/Infantile Sialic Acid Storage Disease Sarcosine Oncometabolite Pathway Segawa Syndrome Selenoamino Acid Metabolism Sepiapterin Reductase Deficiency Sialuria or French Type Sialuria Spirapril Action Pathway Tay-Sachs Disease Telmisartan Action Pathway Temocapril Action Pathway Trandolapril Action Pathway Valsartan Action Pathway Viral Sepsis ( show more show less )
Q15849 View in UniProt HMDBP02521 View in HMDB	Urea transporter 2 Gene Name: SLC14A2 Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.	Amiloride Action Pathway Bendroflumethiazide Action Pathway Blue Diaper Syndrome Bumetanide Action Pathway Chlorothiazide Action Pathway Chlorthalidone Action Pathway Cyclothiazide Action Pathway Cystinuria Eplerenone Action Pathway Ethacrynic Acid Action Pathway Furosemide Action Pathway Glucose Transporter Defect (SGLT2) Hartnup Disorder Hydrochlorothiazide Action Pathway Hydroflumethiazide Action Pathway Iminoglycinuria Indapamide Action Pathway Kidney Function - Collecting Duct Lysinuric Protein Intolerance Lysinuric Protein Intolerance (LPI) Methyclothiazide Action Pathway Metolazone Action Pathway Polythiazide Action Pathway Quinethazone Action Pathway Spironolactone Action Pathway Torsemide Action Pathway Triamterene Action Pathway Trichlormethiazide Action Pathway ( show more show less )
A8K5J1 View in UniProt	Uridine monophosphate synthetase isoform A Gene Name: UMPS	beta-Ureidopropionase Deficiency Dihydropyrimidinase Deficiency MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) Pyrimidine Metabolism UMP Synthase Deficiency (Orotic Aciduria)
O95045 View in UniProt HMDBP06424 View in HMDB	Uridine phosphorylase 2 Gene Name: UPP2 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.	beta-Ureidopropionase Deficiency Dihydropyrimidinase Deficiency MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) Pyrimidine Metabolism UMP Synthase Deficiency (Orotic Aciduria)
Q9NWZ5 View in UniProt HMDBP07410 View in HMDB	Uridine-cytidine kinase-like 1 Gene Name: UCKL1 May contribute to UTP accumulation needed for blast transformation and proliferation.	beta-Ureidopropionase Deficiency Dihydropyrimidinase Deficiency MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) Pyrimidine Metabolism UMP Synthase Deficiency (Orotic Aciduria)
Q96N76 View in UniProt HMDBP00914 View in HMDB	Urocanate hydratase Gene Name: UROC1	Histidine Metabolism Histidinemia
DB00013 View in DrugBank	Urokinase	Urokinase Action Pathway
P06132 View in UniProt HMDBP00250 View in HMDB	Uroporphyrinogen decarboxylase Gene Name: UROD Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	Acute Intermittent Porphyria Congenital Erythropoietic Porphyria (CEP) or Gunther Disease Hereditary Coproporphyria (HCP) Porphyria Variegata (PV) Porphyrin Metabolism
P10746 View in UniProt HMDBP00357 View in HMDB	Uroporphyrinogen-III synthase Gene Name: UROS Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).	Acute Intermittent Porphyria Congenital Erythropoietic Porphyria (CEP) or Gunther Disease Hereditary Coproporphyria (HCP) Porphyria Variegata (PV) Porphyrin Metabolism
Q16851 View in UniProt HMDBP01074 View in HMDB	UTP--glucose-1-phosphate uridylyltransferase Gene Name: UGP2 Plays a central role as a glucosyl donor in cellular metabolic pathways.	Congenital Disorder of Glycosylation CDG-IId Galactose Metabolism Galactosemia Galactosemia II (GALK) Galactosemia III GLUT-1 Deficiency Syndrome Glycogen Synthetase Deficiency Glycogenosis, Type III. Cori Disease, Debrancher Glycogenosis Glycogenosis, Type IV. Amylopectinosis, Anderson Disease Glycogenosis, Type VI. Hers Disease Lactose Synthesis Mucopolysaccharidosis VII. Sly Syndrome Nucleotide Sugars Metabolism Starch and Sucrose Metabolism Sucrase-Isomaltase Deficiency ( show more show less )
P54725 View in UniProt	UV excision repair protein RAD23 homolog A	Nucleotide Excision Repair
P15313 View in UniProt HMDBP01294 View in HMDB	V-type proton ATPase subunit B, kidney isoform Gene Name: ATP6V1B1 Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells	Kidney Function - Collecting Duct
P26640 View in UniProt HMDBP00651 View in HMDB	Valine--tRNA ligase Gene Name: VARS	Protein Synthesis: Valine
P15692 View in UniProt HMDBP02130 View in HMDB	Vascular endothelial growth factor A Gene Name: VEGFA Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth	Bevacizumab Action Pathway
P17948 View in UniProt HMDBP01462 View in HMDB	Vascular endothelial growth factor receptor 1 Gene Name: FLT1 Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis	Bevacizumab Action Pathway
P35968 View in UniProt HMDBP01272 View in HMDB	Vascular endothelial growth factor receptor 2 Gene Name: KDR Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions	Bevacizumab Action Pathway Vatalanib Action Pathway
P30518 View in UniProt HMDBP01725 View in HMDB	Vasopressin V2 receptor Gene Name: AVPR2 Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase	Vasopressin Regulation of Water Homeostasis
O14975 View in UniProt HMDBP01946 View in HMDB	Very long-chain acyl-CoA synthetase Gene Name: SLC27A2 Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).	Phytanic Acid Peroxisomal Oxidation Refsum Disease
P49748 View in UniProt HMDBP08259 View in HMDB	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial Gene Name: ACADVL Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons.	Carnitine Palmitoyl Transferase Deficiency I Carnitine Palmitoyl Transferase Deficiency II Ethylmalonic Encephalopathy Fatty Acid Metabolism Glutaric Aciduria Type I Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD) Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD) Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency) Trifunctional Protein Deficiency Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD) ( show more show less )
P63027 View in UniProt	Vesicle-associated membrane protein 2 Gene Name: VAMP2 Involved in the targeting and/or fusion of transport vesicles to their target membrane.	Pancreas Function - Beta Cell

Showing 1541 - 1560 of 1576 proteins

Browsing Proteins

Protein ID

Protein

Pathways

Unknown

Unknown

Q15849

HMDBP02521

Urea transporter 2

A8K5J1

Uridine monophosphate synthetase isoform A

O95045

HMDBP06424

Uridine phosphorylase 2

Q9NWZ5

HMDBP07410

Uridine-cytidine kinase-like 1

Q96N76

HMDBP00914

Urocanate hydratase

DB00013

Urokinase

P06132

HMDBP00250

Uroporphyrinogen decarboxylase

P10746

HMDBP00357

Uroporphyrinogen-III synthase

Q16851

HMDBP01074

UTP--glucose-1-phosphate uridylyltransferase

P54725

UV excision repair protein RAD23 homolog A

P15313

HMDBP01294

V-type proton ATPase subunit B, kidney isoform

P26640

HMDBP00651

Valine--tRNA ligase

P15692

HMDBP02130

Vascular endothelial growth factor A

P17948

HMDBP01462

Vascular endothelial growth factor receptor 1

P35968

HMDBP01272

Vascular endothelial growth factor receptor 2

P30518

HMDBP01725

Vasopressin V2 receptor

O14975

HMDBP01946

Very long-chain acyl-CoA synthetase

P49748

HMDBP08259

Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

P63027

Vesicle-associated membrane protein 2