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Showing 1541 - 1560 of 1576 proteins

Protein ID




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Urea transporter 2

Gene Name: SLC14A2

Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.


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Uridine monophosphate synthetase isoform A

Gene Name: UMPS


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Uridine phosphorylase 2

Gene Name: UPP2

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.


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Uridine-cytidine kinase-like 1

Gene Name: UCKL1

May contribute to UTP accumulation needed for blast transformation and proliferation.


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Urocanate hydratase

Gene Name: UROC1


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Uroporphyrinogen decarboxylase

Gene Name: UROD

Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


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Uroporphyrinogen-III synthase

Gene Name: UROS

Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).


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UTP--glucose-1-phosphate uridylyltransferase

Gene Name: UGP2

Plays a central role as a glucosyl donor in cellular metabolic pathways.


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UV excision repair protein RAD23 homolog A


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V-type proton ATPase subunit B, kidney isoform

Gene Name: ATP6V1B1

Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells


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Valine--tRNA ligase

Gene Name: VARS


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Vascular endothelial growth factor A

Gene Name: VEGFA

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth


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Vascular endothelial growth factor receptor 1

Gene Name: FLT1

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis


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Vascular endothelial growth factor receptor 2

Gene Name: KDR

Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions


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Vasopressin V2 receptor

Gene Name: AVPR2

Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase


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Very long-chain acyl-CoA synthetase

Gene Name: SLC27A2

Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).


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Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

Gene Name: ACADVL

Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons.


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Vesicle-associated membrane protein 2

Gene Name: VAMP2

Involved in the targeting and/or fusion of transport vesicles to their target membrane.
Showing 1541 - 1560 of 1576 proteins