SMPDB

Showing 141 - 160 of 1576 proteins

Protein ID	Protein Description	Pathway Class	Pathways
P18124 View in UniProt	60S ribosomal protein L7 Gene Name: RPL7 Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.	Metabolic	Protein Synthesis: Alanine Protein Synthesis: Arginine Protein Synthesis: Asparagine Protein Synthesis: Aspartic Acid Protein Synthesis: Cysteine Protein Synthesis: Glutamic Acid Protein Synthesis: Glutamine Protein Synthesis: Glycine Protein Synthesis: Histidine Protein Synthesis: Isoleucine Protein Synthesis: Leucine Protein Synthesis: Lysine Protein Synthesis: Methionine Protein Synthesis: Phenylalanine Protein Synthesis: Proline Protein Synthesis: Serine Protein Synthesis: Threonine Protein Synthesis: Tryptophan Protein Synthesis: Tyrosine Protein Synthesis: Valine ( show more show less )
P62424 View in UniProt	60S ribosomal protein L7a Gene Name: RPL7A	Metabolic	Protein Synthesis: Alanine Protein Synthesis: Arginine Protein Synthesis: Asparagine Protein Synthesis: Aspartic Acid Protein Synthesis: Cysteine Protein Synthesis: Glutamic Acid Protein Synthesis: Glutamine Protein Synthesis: Glycine Protein Synthesis: Histidine Protein Synthesis: Isoleucine Protein Synthesis: Leucine Protein Synthesis: Lysine Protein Synthesis: Methionine Protein Synthesis: Phenylalanine Protein Synthesis: Proline Protein Synthesis: Serine Protein Synthesis: Threonine Protein Synthesis: Tryptophan Protein Synthesis: Tyrosine Protein Synthesis: Valine ( show more show less )
P62917 View in UniProt	60S ribosomal protein L8 Gene Name: RPL8	Metabolic	Protein Synthesis: Alanine Protein Synthesis: Arginine Protein Synthesis: Asparagine Protein Synthesis: Aspartic Acid Protein Synthesis: Cysteine Protein Synthesis: Glutamic Acid Protein Synthesis: Glutamine Protein Synthesis: Glycine Protein Synthesis: Histidine Protein Synthesis: Isoleucine Protein Synthesis: Leucine Protein Synthesis: Lysine Protein Synthesis: Methionine Protein Synthesis: Phenylalanine Protein Synthesis: Proline Protein Synthesis: Serine Protein Synthesis: Threonine Protein Synthesis: Tryptophan Protein Synthesis: Tyrosine Protein Synthesis: Valine ( show more show less )
P32969 View in UniProt	60S ribosomal protein L9 Gene Name: RPL9	Metabolic	Protein Synthesis: Alanine Protein Synthesis: Arginine Protein Synthesis: Asparagine Protein Synthesis: Aspartic Acid Protein Synthesis: Cysteine Protein Synthesis: Glutamic Acid Protein Synthesis: Glutamine Protein Synthesis: Glycine Protein Synthesis: Histidine Protein Synthesis: Isoleucine Protein Synthesis: Leucine Protein Synthesis: Lysine Protein Synthesis: Methionine Protein Synthesis: Phenylalanine Protein Synthesis: Proline Protein Synthesis: Serine Protein Synthesis: Threonine Protein Synthesis: Tryptophan Protein Synthesis: Tyrosine Protein Synthesis: Valine ( show more show less )
Q9UNU6 View in UniProt HMDBP06125 View in HMDB	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Gene Name: CYP8B1 Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.	Metabolic
Q9UBM7 View in UniProt HMDBP00548 View in HMDB	7-dehydrocholesterol reductase Gene Name: DHCR7 Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).	Metabolic	Bloch Pathway (Cholesterol Biosynthesis) Kandutsch-Russell Pathway (Cholesterol Biosynthesis)
Q9NRR6 View in UniProt HMDBP01572 View in HMDB	72 kDa inositol polyphosphate 5-phosphatase Gene Name: INPP5E Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2. Specific for lipid substrates, inactive towards water soluble inositol phosphates.	Metabolic	Joubert Syndrome Phosphatidylinositol Phosphate Metabolism
P08253 View in UniProt HMDBP02804 View in HMDB	72 kDa type IV collagenase Gene Name: MMP2 PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels	Metabolic	GnRH Signaling Pathway
P11021 View in UniProt	78 kDa glucose-regulated protein Gene Name: HSPA5	Metabolic	Acetaminophen Metabolism Pathway Androstenedione Metabolism Estrone Metabolism Etoposide Action Pathway Etoposide Metabolism Pathway Ibuprofen Action Pathway Ibuprofen Metabolism Pathway Irinotecan Action Pathway Irinotecan Metabolism Pathway Morphine Action Pathway Morphine Metabolism Pathway Phenytoin (Antiarrhythmic) Action Pathway Retinol Metabolism Sorafenib Metabolism Pathway (old) Vitamin A Deficiency ( show more show less )
Q15118 View in UniProt HMDBP01172 View in HMDB	[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial Gene Name: PDK1 Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism	Metabolic	Fc Epsilon Receptor I Signaling in Mast Cells
DB00054 View in DrugBank	Abciximab Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor and other adhesive molecules.	Metabolic	Abciximab Action Pathway (old)
Q9BWD1 View in UniProt HMDBP00013 View in HMDB	Acetyl-CoA acetyltransferase, cytosolic Gene Name: ACAT2	Metabolic	Alendronate Action Pathway Atorvastatin Action Pathway Cerivastatin Action Pathway CHILD Syndrome Cholesteryl Ester Storage Disease Chondrodysplasia Punctata II, X-Linked Dominant (CDPX2) Desmosterolosis Fluvastatin Action Pathway Hyper-IgD Syndrome Hypercholesterolemia Ibandronate Action Pathway Lovastatin Action Pathway Lysosomal Acid Lipase Deficiency (Wolman Disease) Mevalonic Aciduria Pamidronate Action Pathway Pravastatin Action Pathway Risedronate Action Pathway Rosuvastatin Action Pathway Simvastatin Action Pathway Smith-Lemli-Opitz Syndrome (SLOS) Steroid Biosynthesis Wolman Disease Zoledronate Action Pathway ( show more show less )
P24752 View in UniProt HMDBP00038 View in HMDB	Acetyl-CoA acetyltransferase, mitochondrial Gene Name: ACAT1 Plays a major role in ketone body metabolism.	Metabolic	2-Aminoadipic 2-Oxoadipic Aciduria 2-Methyl-3-hydroxybutyryl-CoA Dehydrogenase Deficiency 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency 3-Hydroxyisobutyric Aciduria 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I 3-Methylglutaconic Aciduria Type I 3-Methylglutaconic Aciduria Type III 3-Methylglutaconic Aciduria Type IV beta-Ketothiolase Deficiency Butyrate Metabolism Carnitine Palmitoyl Transferase Deficiency I Carnitine Palmitoyl Transferase Deficiency II Ethylmalonic Encephalopathy Fatty Acid Metabolism Glutaric Aciduria Type I Glutaric Aciduria Type I Hyperlysinemia I, Familial Hyperlysinemia II or Saccharopinuria Isobutyryl-CoA Dehydrogenase Deficiency Isovaleric Acidemia Isovaleric Aciduria Ketone Body Metabolism Leigh Syndrome Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD) Lysine Degradation Malonic Aciduria Malonyl-CoA Decarboxylase Deficiency Maple Syrup Urine Disease Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD) Methylmalonate Semialdehyde Dehydrogenase Deficiency Methylmalonic Aciduria Methylmalonic Aciduria Due to Cobalamin-Related Disorders Mevalonate Pathway Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids Primary Hyperoxaluria II, PH2 Propanoate Metabolism Propionic Acidemia Pyridoxine Dependency with Seizures Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) Pyruvate Dehydrogenase Complex Deficiency Pyruvate Kinase Deficiency Pyruvate Metabolism Saccharopinuria/Hyperlysinemia II Short-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency (HADH) Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency) Succinyl CoA: 3-Ketoacid CoA Transferase Deficiency Trifunctional Protein Deficiency Valine, Leucine, and Isoleucine Degradation Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD) ( show more show less )
Q13085 View in UniProt HMDBP00047 View in HMDB	Acetyl-CoA carboxylase 1 Gene Name: ACACA Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.	Metabolic	Fatty Acid Biosynthesis Leigh Syndrome LPS and Citrate Signaling and Inflammation Malonic Aciduria Malonyl-CoA Decarboxylase Deficiency Methylmalonic Aciduria Due to Cobalamin-Related Disorders Primary Hyperoxaluria II, PH2 Propanoate Metabolism Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) Pyruvate Dehydrogenase Complex Deficiency Pyruvate Kinase Deficiency Pyruvate Metabolism ( show more show less )
Q9NUB1 View in UniProt HMDBP00042 View in HMDB	Acetyl-coenzyme A synthetase 2-like, mitochondrial Gene Name: ACSS1 Important for maintaining normal body temperature during fasting and for energy homeostasis. Essential for energy expenditure under ketogenic conditions (By similarity). Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2).	Metabolic	Disulfiram Action Pathway Ethanol Degradation Malonic Aciduria Malonyl-CoA Decarboxylase Deficiency Methylmalonic Aciduria Due to Cobalamin-Related Disorders Propanoate Metabolism ( show more show less )
Q9NR19 View in UniProt HMDBP00037 View in HMDB	Acetyl-coenzyme A synthetase, cytoplasmic Gene Name: ACSS2 Activates acetate so that it can be used for lipid synthesis or for energy generation.	Metabolic	Disulfiram Action Pathway Ethanol Degradation Leigh Syndrome Primary Hyperoxaluria II, PH2 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) Pyruvate Dehydrogenase Complex Deficiency Pyruvate Kinase Deficiency Pyruvate Metabolism ( show more show less )
P22303 View in UniProt HMDBP00524 View in HMDB	Acetylcholinesterase Gene Name: ACHE Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.	Metabolic	Phospholipid Biosynthesis
P46597 View in UniProt HMDBP00101 View in HMDB	Acetylserotonin O-methyltransferase Gene Name: ASMT Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity.	Metabolic	Tryptophan Metabolism
Q99798 View in UniProt HMDBP00725 View in HMDB	Aconitate hydratase, mitochondrial Gene Name: ACO2 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity).	Metabolic	2-Ketoglutarate Dehydrogenase Complex Deficiency Aerobic Glycolysis (Warburg Effect) Citric Acid Cycle Congenital Lactic Acidosis Fumarase Deficiency Glutaminolysis and Cancer Mitochondrial Complex II Deficiency Pyruvate Dehydrogenase Deficiency (E2) Pyruvate Dehydrogenase Deficiency (E3) The Oncogenic Action of 2-Hydroxyglutarate The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria The Oncogenic Action of Fumarate The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria The Oncogenic Action of Succinate ( show more show less )
P60709 View in UniProt	Actin, cytoplasmic 1 Gene Name: ACTB Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.	Metabolic	Rac 1 Cell Motility Signaling Pathway

Showing 141 - 160 of 1576 proteins

Browsing Proteins

Protein ID

Protein Description

Pathway Class

Pathways

P18124

60S ribosomal protein L7

P62424

60S ribosomal protein L7a

P62917

60S ribosomal protein L8

P32969

60S ribosomal protein L9

Q9UNU6

HMDBP06125

7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase

Q9UBM7

HMDBP00548

7-dehydrocholesterol reductase

Q9NRR6

HMDBP01572

72 kDa inositol polyphosphate 5-phosphatase

P08253

HMDBP02804

72 kDa type IV collagenase

P11021

78 kDa glucose-regulated protein

Q15118

HMDBP01172

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

DB00054

Abciximab

Q9BWD1

HMDBP00013

Acetyl-CoA acetyltransferase, cytosolic

P24752

HMDBP00038

Acetyl-CoA acetyltransferase, mitochondrial

Q13085

HMDBP00047

Acetyl-CoA carboxylase 1

Q9NUB1

HMDBP00042

Acetyl-coenzyme A synthetase 2-like, mitochondrial

Q9NR19

HMDBP00037

Acetyl-coenzyme A synthetase, cytoplasmic

P22303

HMDBP00524

Acetylcholinesterase

P46597

HMDBP00101

Acetylserotonin O-methyltransferase

Q99798

HMDBP00725

Aconitate hydratase, mitochondrial

P60709

Actin, cytoplasmic 1