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Sodium-coupled
neutral amino
acid
transporter 4
Solute carrier
family 2,
facilitated
glucose
transporter
member 2
Solute carrier
family 2,
facilitated
glucose
transporter
member 4
Neutral amino
acid
transporter A
Alanine
aminotransferase
2
Alanine
aminotransferase
1
Glutamate
dehydrogenase
1,
mitochondrial
D-Glucose
Pyruvic acid
Pyruvic acid
D-Glucose
NH
3
L-Glutamic acid
L-Alanine
L-Alanine
D-Glucose
L-Glutamic acid
L-Glutamic acid
H
+
H
+
L-Alanine
Oxoglutaric acid
Oxoglutaric acid
H
2
O
NAD
Oxoglutaric acid
NADH
Glycolysis
Aspartate
Metabolism
Gluconeogenesis
Urea Cycle
Protein
Degradation
Mitochondrial
glutamate
carrier 1
Pyridoxal
5'-phosphate
Pyridoxal
5'-phosphate
Mitochondria
Blood Vessel
Myocyte
Muscle
Liver
Hepatocyte
Mitochondrial Matrix
Mitochondrial Inner Membrane
Mitochondrial Outer Membrane
Mitochondria
SLC38A4
SLC2A2
SLC2A4
SLC1A4
GPT2
GPT
GLUD1
D-Glucose
Pyruvic acid
Pyruvic acid
D-Glucose
Ammonia
L-Glutamic acid
L-Alanine
L-Alanine
D-Glucose
L-Glutamic acid
L-Glutamic acid
Hydrogen Ion
Hydrogen Ion
L-Alanine
Oxoglutaric
acid
Oxoglutaric
acid
Water
NAD
Oxoglutaric
acid
NADH
Glycolysis
Aspartate
Metabolism
Gluconeogenesis
Urea Cycle
Protein
Degradation
SLC25A22
SLC38A4
SLC2A2
SLC2A4
SLC1A4
GPT2
GPT
GLUD1
D-Glc
Pyr
Pyr
D-Glc
NH
3
Glu
Ala
Ala
D-Glc
Glu
Glu
H
+
H
+
Ala
AKG
AKG
H
2
O
NAD
AKG
NADH
PW000146
PW000002
PW000152
PW000162
Pro Deg
SLC25A22
Pyr-5'P
Pyr-5'P
Mitochondria
Blood Vessel
Myocyte
Muscle
Liver
Hepatocyte
Mitochondrial Matrix
Mitochondrial Inner Membrane
Mitochondrial Outer Membrane
Mitochondria
SLC38A4
SLC2A2
SLC2A4
SLC1A4
GPT2
GPT
GLUD1
D-Glc
Pyr
Pyr
D-Glc
NH3
Glu
Ala
Ala
D-Glc
Glu
Glu
H+
H+
Ala
AKG
AKG
H2O
NAD
AKG
NADH
PW000146
PW000002
PW000152
PW000162
Pro Deg