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Tyrosine
aminotransferase
Aspartate
aminotransferase,
cytoplasmic
4-
hydroxyphenylpyruvate
dioxygenase
Maleylacetoacetate
isomerase
Fumarylacetoacetase
Aromatic-L-
amino-acid
decarboxylase
Aldehyde
dehydrogenase,
dimeric
NADP-preferring
Tyrosinase
Dopamine beta-
hydroxylase
Aromatic-L-
amino-acid
decarboxylase
Tyrosinase
Tyrosinase
Tyrosinase
L-dopachrome
tautomerase
Tyrosinase
Phenylethanolamine
N-
methyltransferase
Amine oxidase
[flavin-
containing] A
Amine oxidase
[flavin-
containing] A
Amine oxidase
[flavin-
containing] A
Amine oxidase
[flavin-
containing] A
Aldehyde
dehydrogenase,
dimeric
NADP-preferring
Alcohol
dehydrogenase
1A
Homogentisate
1,2-dioxygenase
Macrophage
migration
inhibitory
factor
Amiloride-
sensitive amine
oxidase
[copper-
containing]
Amine oxidase
[flavin-
containing] A
Tyrosinase
Catechol O-
methyltransferase
Aldehyde
dehydrogenase,
dimeric
NADP-preferring
Catechol O-
methyltransferase
Catechol O-
methyltransferase
Catechol O-
methyltransferase
Catechol O-
methyltransferase
Amine oxidase
[flavin-
containing] A
Amine oxidase
[flavin-
containing] A
3-
hydroxyanthranilate
3,4-dioxygenase
Catechol O-
methyltransferase
Aldehyde
dehydrogenase,
dimeric
NADP-preferring
Accumulation
L-Tyrosine
Oxoglutaric acid
4-Hydroxyphenylpyruvic acid
L-Glutamic acid
L-Aspartic acid
Oxalacetic acid
O
2
Homogentisic acid
CO
2
Accumulation
Maleylacetoacetic acid
Accumulation
4-Fumarylacetoacetic acid
H
2
O
Acetoacetic acid
Fumaric acid
Tyramine
CO
2
Homovanillin
NADP
H
2
O
p-Hydroxyphenylacetic acid
NADPH
O
2
Dopamine
H
2
O
Ascorbic acid
O
2
Norepinephrine
Dehydroascorbic acid
H
2
O
L-Dopa
Tetrahydrobiopterin
4a-Hydroxytetrahydrobiopterin
O
2
Dopaquinone
H
2
O
Leucodopachrome
L-Dopachrome
O
2
5,6-Dihydroxyindole
H
2
O
O
2
Indole-5,6-quinone
H
2
O
Melanin