Guanosine diphosphate
Guanine nucleotide-binding protein G(T) subunit gamma-T1
Gβ
cAMP-dependent protein kinase catalytic subunit beta
5-hydroxytryptamine receptor 6
CPD-8587
BioCyc
Serotonin
cAMP
Ethylene-responsive transcription factor ESR1
C00035
KEGG Compound
ReactionCatalysis1841
ACTIVATION
BTO:0000142
BRENDA TISSUE ONTOLOGY
ReactionCatalysis1845
ACTIVATION
HMDB0000259
HMDB
cAMP-dependent protein kinase catalytic subunit beta
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
ReactionCatalysis1844
ACTIVATION
SMILES
NCCC1=CNC2=CC=C(O)C=C12
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reaction596
false
Adenosine triphosphate → Pyrophosphate + cAMP
LEFT_TO_RIGHT
HMDB0000250
HMDB
1.0
SMILES
[O-]P([O-])(=O)OP([O-])([O-])=O
14000-31-8
CAS
Guanine nucleotide-binding protein G(T) subunit gamma-T1
1.0
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Brain
Phosphate
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
HMDB0000538
HMDB
Ethylene-responsive transcription factor ESR1
1.0
C00044
KEGG Compound
ATP
BioCyc
5202
PubChem-compound
5-hydroxytryptamine receptor 6
1.0
P63092
UniProt
559142
ChemSpider
1.0
Reaction2335
false
5-hydroxytryptamine receptor 6 + Guanosine triphosphate → 5-hydroxytryptamine receptor 6 + Guanine nucleotide-binding protein alpha + Guanine nucleotide-binding protein gamma-beta + Guanosine diphosphate
LEFT_TO_RIGHT
Guanine nucleotide-binding protein gamma-beta
C10H12N5O6P
cAMP
329.05252
1.0
CHEBI:15422
ChEBI
PW000444
PathWhiz
Homo sapiens
P62136
UniProt
1.0
5742
ChemSpider
C00575
KEGG Compound
GO:0005829
GENE ONTOLOGY
2.7.11.11
false
2.7.11.11
Cyclic AMP-responsive element-binding protein 1 → Cyclic AMP-responsive element-binding protein 1 + Phosphate
LEFT_TO_RIGHT
Excitatory Neurotransmissiom
SubPathway
50-67-9
CAS
C10H16N5O13P3
Adenosine triphosphate
506.99576
Pyrophosphate
O4P
Phosphate
94.95342
5851
ChemSpider
8977
PubChem-compound
6830
PubChem-compound
C10H15N5O11P2
Guanosine diphosphate
443.02432
SMILES
NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O
PPI
BioCyc
SMP0000312
SMPDB
1.0
TransportCatalysis224
ACTIVATION
9606
TAXONOMY
C10H16N5O14P3
Guanosine triphosphate
522.99066
1.0
Guanosine triphosphate
Transport272
false
Serotonin (→) Transport: Homo sapiens, Cell, Extracellular Space to Homo sapiens, Cell, Cytosol
LEFT_TO_RIGHT
P62873
UniProt
Cytosol
Serotonin
8630
ChemSpider
1.0
Guanine nucleotide-binding protein alpha-beta-gamma
HMDB0000058
HMDB
SMILES
[O-]P([O-])([O-])=O
GO:0005886
GENE ONTOLOGY
2.7.11.11
false
2.7.11.11
cAMP → cAMP + cAMP-dependent protein kinase catalytic subunit beta
LEFT_TO_RIGHT
C00009
KEGG Compound
Cell Membrane
Cyclic AMP-responsive element-binding protein 1
1.0
14265-44-2
CAS
6569
ChemSpider
HMDB0001429
HMDB
P22694
UniProt
SMILES
NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
CHEBI:18361
ChEBI
CHEBI:17552
ChEBI
SMILES
NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1
CHEBI:18367
ChEBI
P63211
UniProt
GTP
BioCyc
1032
ChemSpider
C00002
KEGG Compound
P16220
UniProt
GDP-4-DEHYDRO-6-DEOXY-D-MANNOSE
BioCyc
GO:0005634
GENE ONTOLOGY
BiologicalState85
Homo sapiens, Brain
CHEBI:28790
ChEBI
HMDB0001273
HMDB
CHEBI:17489
ChEBI
644102
PubChem-compound
CAMP
BioCyc
SubPathwayInteraction656
SubPathway656Reaction
SubPathwayReaction
ReactionCatalysis1816
ACTIVATION
cAMP-dependent protein kinase catalytic subunit beta
SubPathwayInput
SMILES
NC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)C(=O)N1
1.0
1.0
5-hydroxytryptamine receptor 6
Extracellular Space
C00013
KEGG Compound
2.7.11.11
false
2.7.11.11
Ethylene-responsive transcription factor ESR1 → Ethylene-responsive transcription factor ESR1 + Phosphate
LEFT_TO_RIGHT
HMDB0001201
HMDB
O7P2
Pyrophosphate
173.91193
Cyclic AMP-responsive element-binding protein 1
5957
PubChem-compound
Q9SAD4
UniProt
3.1.3.16
false
3.1.3.16
Cyclic AMP-responsive element-binding protein 1 + Phosphate → Cyclic AMP-responsive element-binding protein 1
LEFT_TO_RIGHT
C10H12N2O
Serotonin
176.09496
3.1.3.16
false
3.1.3.16
Ethylene-responsive transcription factor ESR1 + Phosphate → Ethylene-responsive transcription factor ESR1
LEFT_TO_RIGHT
86-01-1
CAS
1.0
Nucleus
ReactionCatalysis2235
ACTIVATION
1061
PubChem-compound
6076
PubChem-compound
1.0
CHEBI:15996
ChEBI
Gβ
5013
ChemSpider
C00780
KEGG Compound
56-65-5
CAS
P50406
UniProt
Adenosine triphosphate
ReactionCatalysis1834
ACTIVATION
GO:0005615
GENE ONTOLOGY
1.0
146-91-8
CAS
60-92-4
CAS