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Histone-lysine N- methyltransferase SETD7 Trimethyllysine dioxygenase, mitochondrial Serine hydroxymethyltransferase, cytosolic 4- trimethylaminobutyraldehyde dehydrogenase Gamma- butyrobetaine dioxygenase N6,N6,N6- Trimethyl-L- lysine N6,N6,N6- Trimethyl-L- lysine 4- Trimethylammoniobutanoic acid 4- Trimethylammoniobutanoic acid L-Lysine S- Adenosylmethionine S- Adenosylhomocysteine Oxoglutaric acid O2 3-Hydroxy- N6,N6,N6- trimethyl-L- lysine Succinic acid CO2 Glycine 4- Trimethylammoniobutanal NAD H2O NADH H+ Oxoglutaric acid O2 L-Carnitine Succinic acid CO2 Fe2+ Fe2+ Ascorbic acid Protein containing a lysine residue Protein containing a lysine residue Protein degradation Pyridoxal 5'-phosphate Nucleus Nuclear Membrane Nucleoplasm Extacellular Space Intracellular Space Intracellular Space Mitochondria Liver Kidney
Nucleus SETD7 TMLHE SHMT1 ALDH9A1 BBOX1 N6,N6,N6- Trimethyl-L- lysine N6,N6,N6- Trimethyl-L- lysine 4- Trimethylammoniobutanoic acid 4- Trimethylammoniobutanoic acid L-Lysine S- Adenosylmethionine S- Adenosylhomocysteine Oxoglutaric acid Oxygen 3-Hydroxy- N6,N6,N6- trimethyl-L- lysine Succinic acid Carbon dioxide Glycine 4- Trimethylammoniobutanal NAD Water NADH Hydrogen Ion Oxoglutaric acid Oxygen L-Carnitine Succinic acid Carbon dioxide Protein containing a lysine residue Protein containing a lysine residue Protein degradation
SETD7 TMLHE SHMT1 ALDH9A1 BBOX1 TML-Lys TML-Lys 4-TMaba 4-TMaba Lys SAMe SAH AKG O2 3HNNNTL Succini CO2 Gly 4-TMAmB NAD H2O NADH H+ AKG O2 L-Carnt Succini CO2 Fe2+ Fe2+ VitC PCALR PCALR Pro deg Pyr-5'P Nucleus Nuclear Membrane Nucleoplasm Extacellular Space Intracellular Space Intracellular Space Mitochondria Liver Kidney