3-oxo-5-alpha-
steroid
4-dehydrogenase 1
Aldo-keto
reductase family
1 member C4
UDP-
glucuronosyltransferase
1-1
Cytochrome P450
19A1
Cytochrome P450
19A1
Cytochrome P450
19A1
Testosterone
17-beta-
dehydrogenase 3
Cytochrome P450
11B1,
mitochondrial
3-oxo-5-beta-
steroid
4-dehydrogenase
UDP-
glucuronosyltransferase
1-1
Corticosteroid
11-beta-
dehydrogenase
isozyme 1
Aldo-keto
reductase family
1 member C4
11b-
Hydroxyandrost-
4-ene-3,17- dione
11b-
Hydroxyandrost-
4-ene-3,17- dione
Androstenedione
NADPH
H+
Androstanedione
NADP
NADH
H+
Androsterone
NAD
Uridine
diphosphate
glucuronic acid
Androsterone
glucuronide
Uridine
5'-diphosphate
O2
19-
Hydroxyandrost-
4-ene-3,17- dione
H2O
O2
19-Oxoandrost-
4-ene-3,17- dione
H2O
O2
Estrone
Formic acid
H2O
Testosterone
NAD
NADH
H+
O2
H+
H2O
NADPH
H+
NADP
Etiocholanedione
Etiocholanolone
Uridine
diphosphate
glucuronic acid
Etiocholanolone
glucuronide
Uridine
5'-diphosphate
NADP
NADPH
H+
Adrenosterone
NADH
H+
NAD
Heme
Reduced
flavoprotein
Oxidized
flavoprotein
Reduced
flavoprotein
Oxidized
flavoprotein
Reduced
flavoprotein
Oxidized
flavoprotein
Reduced adrenal
ferredoxin
Oxidized
adrenal
ferredoxin
Heme
Heme
Heme
Endoplasmic Reticulum
Membrane
Cytosol