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Serine palmitoyltransferase 2 Serine palmitoyltransferase 1 Protein dhs-3 Sphingosine kinase 1 Unknown Phospholipid phosphatase homolog 1.2 homolog Sphingosine- 1-phosphate lyase Putative sphingolipid delta(4)- desaturase/C4- monooxygenase Sphingosine- 1-phosphate lyase Sphingosine kinase 1 Unknown Phospholipid phosphatase homolog 1.2 homolog Alkaline ceramidase Ceramide kinase 1 Phospholipid phosphatase homolog 1.2 homolog Unknown Sphingomyelin synthase- related 1 Ectonucleotide pyrophosphatase/phosphodiesterase C27A7.1 Putative UDP- glucuronosyltransferase ugt-58 Putative galactocerebrosidase Putative glucosylceramidase 3 Ceramide glucosyltransferase 3 Unknown Beta-1,4-N- acetylgalactosaminyltransferase bre-4 Unknown SULfatase domain protein Alpha- galactosidase Unknown Unknown Unknown L-Serine Palmityl-CoA 3-Dehydrosphinganine Sphinganine NADPH NADP ATP ADP Sphinganine 1-phosphate ADP ATP Pi O- Phosphoethanolamine Dihydroceramide Ceramide (d18:1/18:0) Sphingosine 1-phosphate Sphingosine ATP ADP ADP ATP Pi ATP CerP(d18:1/12:0) ADP Pi SM(d18:1/18:0) Galactosylceramide (d18:1/16:0) Glucosylceramide Lactosylceramide (d18:1/12:0) Phosphoadenosine phosphosulfate 3-O-Sulfogalactosylceramide (d18:1/24:0) Adenosine 3',5'- diphosphate H2O Sulfate D-Galactose Galabiosylceramide (d18:1/22:0) Phosphoadenosine phosphosulfate Adenosine 3',5'- diphosphate N-acetylneuraminyl- Galactosylceramide Sphinganine Pyridoxal 5'-phosphate Magnesium Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Magnesium Calcium Magnesium Magnesium Zinc Calcium Galabiosylceramide- sulfate Glycine and Serine Metabolism Intracellular space Endoplasmic Reticulum Golgi complex Golgi complex Lysosome Lysosome Endoplasmic Reticulum
sptl-2 sptl-1 dhs-3 sphk-1 Unknown plpp-1.2 spl-1 ttm-5 spl-1 sphk-1 Unknown plpp-1.2 W02F12.2 cerk-1 plpp-1.2 Unknown F53B1.2 C27A7.1 ugt-58 C29E4.10 gba-3 cgt-3 Unknown bre-4 Unknown sul-2 gana-1 Unknown Unknown Unknown L-Serine Palmityl-CoA 3- Dehydrosphinganine Sphinganine NADPH NADP Adenosine triphosphate Adenosine diphosphate Sphinganine 1-phosphate Adenosine diphosphate Adenosine triphosphate Phosphate O- Phosphoethanolamine Dihydroceramide Ceramide (d18:1/18:0) Sphingosine 1-phosphate Sphingosine Adenosine triphosphate Adenosine diphosphate Adenosine diphosphate Adenosine triphosphate Phosphate Adenosine triphosphate CerP(d18:1/12:0) Adenosine diphosphate Phosphate SM(d18:1/18:0) Galactosylceramide (d18:1/16:0) Glucosylceramide Lactosylceramide (d18:1/12:0) Phosphoadenosine phosphosulfate 3-O- Sulfogalactosylceramide (d18:1/24:0) Adenosine 3',5'- diphosphate Water Sulfate D-Galactose Galabiosylceramide (d18:1/22:0) Phosphoadenosine phosphosulfate Adenosine 3',5'- diphosphate N- acetylneuraminyl- Galactosylceramide Sphinganine Galabiosylceramide- sulfate Glycine and Serine Metabolism
sptl-2 sptl-1 dhs-3 sphk-1 plpp- 1.2 spl-1 ttm-5 spl-1 sphk-1 plpp- 1.2 W02F12.2 cerk-1 plpp- 1.2 F53B1.2 C27A7.1 ugt-58 C29E4.10 gba-3 cgt-3 bre-4 sul-2 gana-1 Ser COA16:0 3-DHPG d18:0 NADPH NADP ATP ADP Sphg-1P ADP ATP Pi Ethamp DHCeram Ceram18 S1P Sphingo ATP ADP ADP ATP Pi ATP N-LAURO ADP Pi Sphingo Galcer Glccera Cdh Paps Sulfati A3'5'PP H2O SO4 D-Gal Digalac Paps A3'5'PP NAG d18:0 Pyr-5'P Mg2+ Pyr-5'P Pyr-5'P Mg2+ Ca2+ Mg2+ Mg2+ Zinc Ca2+ GS PW000157 Intracellular space Endoplasmic Reticulum Golgi complex Golgi complex Lysosome Lysosome Endoplasmic Reticulum
sptl-2 sptl-1 dhs-3 sphk-1 plpp- 1.2 spl-1 ttm-5 spl-1 sphk-1 plpp- 1.2 W02F12.2 cerk-1 plpp- 1.2 F53B1.2 C27A7.1 ugt-58 C29E4.10 gba-3 cgt-3 bre-4 sul-2 gana-1 Ser COA16:0 3-DHPG d18:0 NADPH NADP ATP ADP Sphg-1P ADP ATP Pi Ethamp DHCeram Ceram18 S1P Sphingo ATP ADP ADP ATP Pi ATP N-LAURO ADP Pi Sphingo Galcer Glccera Cdh Paps Sulfati A3'5'PP H2O SO4 D-Gal Digalac Paps A3'5'PP NAG d18:0 GS PW000157