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Amidophosphoribosyltransferase Phosphoribosylamine- -glycine ligase Formate- dependent phosphoribosylglycinamide formyltransferase Phosphoribosylformylglycinamidine synthase Phosphoribosylformylglycinamidine cyclo-ligase N5- carboxyaminoimidazole ribonucleotide synthase N5- carboxyaminoimidazole ribonucleotide mutase Phosphoribosylaminoimidazole- succinocarboxamide synthase Adenylosuccinate lyase Inosine-5'- monophosphate dehydrogenase Adenylosuccinate synthetase Adenylosuccinate lyase GMP synthase [glutamine- hydrolyzing] Guanylate kinase Nucleoside diphosphate kinase Ribonucleoside- diphosphate reductase subunit beta Nucleoside diphosphate kinase Ribonucleoside- diphosphate reductase Ribonucleoside- diphosphate reductase subunit beta Nucleoside diphosphate kinase Bifunctional purine biosynthesis protein PurH Cob(I)yrinic acid a,c-diamide adenosyltransferase Unknown Unknown Bifunctional purine biosynthesis protein PurH Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase subunit beta Adenylate kinase ATP synthase subunit c ATP synthase subunit b ATP synthase subunit a ATP synthase epsilon chain ATP synthase subunit delta ATP synthase subunit alpha ATP synthase gamma chain ATP synthase subunit beta Anaerobic ribonucleoside- triphosphate reductase Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase subunit beta Guanosine triphosphate Phosphoribosyl pyrophosphate H2O L-Glutamine 5- Phosphoribosylamine L-Glutamic acid PPi Glycine ATP N1-(5- phospho-β-D- ribosyl)glycinamide Pi ADP H+ ATP Formic acid 5'- Phosphoribosyl- N- formylglycinamide ADP Pi H+ H2O L-Glutamine ATP 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid Pi ADP H+ ATP 5- Aminoimidazole ribonucleotide Pi ADP H+ HCO3- ATP N5- Carboxyaminoimidazole ribonucleotide ADP Pi H+ 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate L-Aspartic acid ATP SAICAR Pi ADP H+ AICAR Fumaric acid Inosinic acid NAD H2O NADH H+ Xanthylic acid L-Aspartic acid GTP GDP Pi H+ N(6)-(1,2- dicarboxyethyl)AMP Fumaric acid Adenosine monophosphate ATP L-Glutamine H2O AMP PPi L-Glutamic acid H+ Guanosine monophosphate ATP ADP Guanosine diphosphate ATP ADP H2O dGDP ATP ADP dGTP Adenosine diphosphate H2O dADP ATP ADP dATP 10- Formyltetrahydrofolate FAICAR tetrahydropteroyl mono-L- glutamate Adenosine triphosphate Cobalamin Triphosphate Adenosylcobalamin Itaconic acid CoA ADP Pi Itaconyl-CoA H2O H2O ATP Pi H+ H2O H+ H2O H2O H2O Magnesium Magnesium Potassium Magnesium Magnesium Magnesium Magnesium Magnesium Magnesium Magnesium Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium 4Fe-4S Adenosine triphosphate dGTP Thymidine 5'-triphosphate Potassium Magnesium Zinc (II) ion 4Fe-4S reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein reduced thioredoxin oxidized thioredoxin a reduced flavodoxin an oxidized flavodoxin a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein Folate Biosynthesis PRPP Biosynthesis Anaerobic ribonucleoside- triphosphate reductase Ribonucleoside- diphosphate reductase Zinc (II) ion
purF purD purT purL purM purK purE purC purB guaB_1 purA purB guaA gmk ndk nrdB_2 ndk nrdE2 nrdB_3 ndk purH cobO Unknown Unknown purH AO964_16150 nrdB_2 adk atpE atpF atpB atpC atpH atpA atpG atpD AO964_16150 AO964_16150 nrdB_3 Guanosine triphosphate Phosphoribosyl pyrophosphate Water L-Glutamine 5- Phosphoribosylamine L-Glutamic acid Pyrophosphate Glycine Adenosine triphosphate N1-(5- phospho-β-D- ribosyl)glycinamide Phosphate Adenosine diphosphate Hydrogen Ion Adenosine triphosphate Formic acid 5'- Phosphoribosyl- N- formylglycinamide Adenosine diphosphate Phosphate Hydrogen Ion Water L-Glutamine Adenosine triphosphate 2- (Formamido)- N1-(5- phospho-D- ribosyl)acetamidine L-Glutamic acid Phosphate Adenosine diphosphate Hydrogen Ion Adenosine triphosphate 5- Aminoimidazole ribonucleotide Phosphate Adenosine diphosphate Hydrogen Ion Hydrogen carbonate Adenosine triphosphate N5- Carboxyaminoimidazole ribonucleotide Adenosine diphosphate Phosphate Hydrogen Ion 5-amino-1-(5- phospho-D- ribosyl)imidazole- 4-carboxylate L-Aspartic acid Adenosine triphosphate SAICAR Phosphate Adenosine diphosphate Hydrogen Ion AICAR Fumaric acid Inosinic acid NAD Water NADH Hydrogen Ion Xanthylic acid L-Aspartic acid Guanosine triphosphate Guanosine diphosphate Phosphate Hydrogen Ion N(6)-(1,2- dicarboxyethyl)AMP Fumaric acid Adenosine monophosphate Adenosine triphosphate L-Glutamine Water Adenosine monophosphate Pyrophosphate L-Glutamic acid Hydrogen Ion Guanosine monophosphate Adenosine triphosphate Adenosine diphosphate Guanosine diphosphate Adenosine triphosphate Adenosine diphosphate Water dGDP Adenosine triphosphate Adenosine diphosphate dGTP Adenosine diphosphate Water dADP Adenosine triphosphate Adenosine diphosphate dATP 10- Formyltetrahydrofolate FAICAR tetrahydropteroyl mono-L- glutamate Adenosine triphosphate Cobalamin Triphosphate Adenosylcobalamin Itaconic acid Coenzyme A Adenosine diphosphate Phosphate Itaconyl-CoA Water Water Adenosine triphosphate Phosphate Hydrogen Ion Water Hydrogen Ion Water Water Water reduced thioredoxin oxidized thioredoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein reduced thioredoxin oxidized thioredoxin a reduced flavodoxin an oxidized flavodoxin a reduced flavodoxin an oxidized flavodoxin a reduced NrdH glutaredoxin- like protein an oxidized NrdH glutaredoxin- like protein Folate Biosynthesis PRPP Biosynthesis AO964_16150 nrdE2
purF purD purT purL purM purK purE purC purB guaB_1 purA purB guaA gmk ndk nrdB_2 ndk nrdE2 nrdB_3 ndk purH cobO purH AO964_16150 nrdB_2 adk atpE atpF atpB atpC atpH atpA atpG atpD AO964_16150 AO964_16150 nrdB_3 GTP PRPP H2O Gln 5-PPRSA Glu PPi Gly ATP N15hg Pi ADP H+ ATP Formate 5PPNFG ADP Pi H+ H2O Gln ATP 2FN5PDR Glu Pi ADP H+ ATP 5-AnRbn Pi ADP H+ HCO3- ATP N5Cr ADP Pi H+ CR Asp ATP SAICAR Pi ADP H+ AICAR Fumarat Imp NAD H2O NADH H+ XntylcA Asp GTP GDP Pi H+ N6AMP Fumarat AMP ATP Gln H2O AMP PPi Glu H+ GSMP ATP ADP GDP ATP ADP H2O dGDP ATP ADP dGTP ADP H2O dADP ATP ADP dATP 10-FTHF FAICAR TaMLGlu ATP Ruvite PPP Adnscbn ItacnAc CoA ADP Pi Itc-CoA H2O H2O ATP Pi H+ H2O H+ H2O H2O H2O Mg2+ Mg2+ K+ Mg2+ Mg2+ Mg2+ Mg2+ Mg2+ Mg2+ Mg2+ ATP dGTP Tm5TP K+ Mg2+ 4Fe-4S ATP dGTP Tm5TP K+ Mg2+ Zinc 4Fe-4S RT OT ARNGLP AONGLP RT OT ARF AOF ARF AOF ARNGLP AONGLP PW000908 PW000909 AO964_16150 nrdE2 Zinc
purF purD purT purL purM purK purE purC purB guaB_1 purA purB guaA gmk ndk nrdB_2 ndk nrdE2 nrdB_3 ndk purH cobO purH AO964_16150 nrdB_2 adk atpE atpF atpB atpC atpH atpA atpG atpD AO964_16150 AO964_16150 nrdB_3 GTP PRPP H2O Gln 5-PPRSA Glu Ppi Gly ATP N15hg Pi ADP H+ ATP Formate 5PPNFG ADP Pi H+ H2O Gln ATP 2FN5PDR Glu Pi ADP H+ ATP 5-AnRbn Pi ADP H+ HCO3 ATP N5Cr ADP Pi H+ CR Asp ATP SAICAR Pi ADP H+ AICAR Fumarat Imp NAD H2O NADH H+ XntylcA Asp GTP GDP Pi H+ N6AMP Fumarat AMP ATP Gln H2O AMP Ppi Glu H+ GSMP ATP ADP GDP ATP ADP H2O dGDP ATP ADP dGTP ADP H2O dADP ATP ADP dATP 10-FTHF FAICAR TaMLGlu ATP Ruvite PPP Adnscbn ItacnAc CoA ADP Pi Itc-CoA H2O H2O ATP Pi H+ H2O H+ H2O H2O H2O RT OT ARNGLP AONGLP RT OT ARF AOF ARF AOF ARNGLP AONGLP PW000908 PW000909 AO964_16150 nrdE2