PathBank

Pathway Description

L-Lactaldehyde Degradation (Aerobic)

Pseudomonas aeruginosa

Category:

Metabolite Pathway

Sub-Category:

Metabolic

Created: 2019-08-12

Last Updated: 2019-09-13

(S)-lactaldehyde is derived from degradation of L-fucose and rhamnose. (S)-lactaldehyde is converted to lactic acid by lactaldehyde dehydrogenase with NAD as cofactor. L-lactate dehydrogenase dehydrogenates lactic acid to pyruvic acid for the pathway of glycolysis and pyruvate dehydrogenase.

References

L-Lactaldehyde Degradation (Aerobic) References

Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV: Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature. 2000 Aug 31;406(6799):959-64. doi: 10.1038/35023079.

Pubmed: 10984043

Yamanishi Y, Mihara H, Osaki M, Muramatsu H, Esaki N, Sato T, Hizukuri Y, Goto S, Kanehisa M: Prediction of missing enzyme genes in a bacterial metabolic network. Reconstruction of the lysine-degradation pathway of Pseudomonas aeruginosa. FEBS J. 2007 May;274(9):2262-73. doi: 10.1111/j.1742-4658.2007.05763.x. Epub 2007 Mar 27.

Pubmed: 17388807

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from SMP0002085

Highlighted elements will appear in red.

Highlight Compounds

	(S)-lactaldehyde
	Hydrogen Ion
	L-Lactic acid
	NAD
	NADH
	Pyruvic acid
	Water

Highlight Proteins

	Glutarate-semialdehyde dehydrogenase DavD
	L-lactate dehydrogenase

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