Oliceridine Opioid Agonist Action Pathway
Calcium (→) Transport: Homo sapiens, Spinal cord, Neuron, Extracellular Space to Homo sapiens, Spinal cord, Neuron, Cytosol
Mu-type opioid receptor (Homo sapiens)_Guanine nucleotide-binding protein G(i) subunit alpha-1 (Homo sapiens)_Gβγ (Homo sapiens)
Voltage-dependent N-type calcium channel subunit alpha-1B
Guanine nucleotide-binding protein G(i) subunit alpha-1
potassium voltage-gated channel subfamily J
Gamma-aminobutyric acid type B receptor subunit 1
Substance P activates Substance P receptor
Gamma-aminobutyric acid receptor subunit alpha-1
G protein-activated inward rectifier potassium channel 2
Voltage-dependent calcium channel subunit alpha-2/delta-2
Gamma-aminobutyric acid receptor subunit beta-2
Gamma-aminobutyric acid type B receptor subunit 2
Gamma-aminobutyric acid receptor subunit gamma-2
G protein-activated inward rectifier potassium channel 3
Voltage-dependent L-type calcium channel subunit beta-1
Voltage-dependent L-type calcium channel subunit beta-4
Adenosine triphosphate → Pyrophosphate + cAMP
G protein-activated inward rectifier potassium channel 4
G protein-activated inward rectifier potassium channel 1
γ-Aminobutyric acid activates GABAA receptor
Oliceridine activates Mu-type opioid receptor (Homo sapiens) + Guanine nucleotide-binding protein G(i) subunit alpha-1 (Homo sapiens) + Gβγ (Homo sapiens)
Oliceridine (→) Transport: Homo sapiens, Blood Vessel to Homo sapiens, Spinal cord, Neuron, Extracellular Space
Mu-type opioid receptor (Homo sapiens) + Guanine nucleotide-binding protein G(i) subunit alpha-1 (Homo sapiens) + Gβγ (Homo sapiens) inhibits N-type calcium channel
Mu-type opioid receptor (Homo sapiens) + Guanine nucleotide-binding protein G(i) subunit alpha-1 (Homo sapiens) + Gβγ (Homo sapiens) activates potassium voltage-gated channel subfamily J
Mu-type opioid receptor (Homo sapiens) + Guanine nucleotide-binding protein G(i) subunit alpha-1 (Homo sapiens) + Gβγ (Homo sapiens) inhibits Adenylate cyclase type 2
γ-Aminobutyric acid activates Gamma-aminobutyric acid type B receptor
γ-Aminobutyric acid (→) Transport: Homo sapiens, Spinal cord, Neuron, Exocytic Vesicle to Homo sapiens, Spinal cord, Neuron, Synapse
Sodium (→) Transport: Homo sapiens, Spinal cord, Neuron, Cytosol to Homo sapiens, Spinal cord, Neuron, Extracellular Space