Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
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Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Eluxadoline Eluxadoline PIS4M1 Eluxadoline PIS4M1 Eluxadoline Eluxadoline PIS1M1 Eluxadoline PIS2M1 Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Kidney Bile Ducts Liver Blood Vessel Blood Vessel Many other Cytochrome P450 enzymes are involved in Phase I (PI) Step 1(S1) and Step 2(S2) reactions. Eluxadoline undergoes metabolism to give Eluxadoline PIS1M1, Eluxadoline PIS2M1 and Eluxadoline PIS4M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown CYP3A4 CYP3A4 CYP3A4 Eluxadoline Eluxadoline PIS4M1 Eluxadoline PIS4M1 Eluxadoline Eluxadoline PIS1M1 Eluxadoline PIS2M1 Urinary Excretion and/or Bile duct Excretion